Retrocopy Name | RPLP2P1 |
|
Species | Homo sapiens | |
Coordinates (hg38) | chr6:27965214-27965471 UCSC | |
Coordinates (T2T) | chr6:27834871-27835128 UCSC | |
Coordinates (hg19) | chr6:27932992-27933249 UCSC | |
Strand | + | |
Parental Sequence | NM_001004.4 | |
Parental seq. overlap | 225 bp | |
Parental seq. overlap (%) | 48.6% | |
Genomic Region |
Intergenic |
|
Retrocopy Summary | RPLP2P1, located on chr6:27965214-27965471, is a retrocopy of the parental gene RPLP2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
Gene Name | RPLP2 |
Full Name | ribosomal protein lateral stalk subunit P2 |
Also known as | D11S2243E|LP2|P2|RPP2 |
Coordinate | chr11:809967-812876 |
Strand | + |
Gene summary | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
Species | Scientific Name | Retrocopy | |
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Chimpanzee | Pan troglodytes | RPLP2P2 |
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Bonobo | Pan paniscus | RPLP2P2 |
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Gorilla | Gorilla gorilla | RPLP2P3 |
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Orangutan | Pongo abelii | RPLP2P2 |
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Gibbon | Nomascus leucogenys | RPLP2P4 |
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Marmoset | Callithrix jacchus | RPLP2P1 |
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Green monkey | Chlorocebus sabaeus | Without Homology |
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Crab-eating macaque | Macaca fascicularis | Without Homology |
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Rhesus | Macaca mulatta | Without Homology |
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Baboon | Papio anubis | Without Homology |
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Golden snub-nosed monkey | Rhinopithecus roxellana | Without Homology |
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Mouse lemur | Microcebus murinus | Without Homology |
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Mouse | Mus musculus | Without Homology |
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Rat | Rattus norvegicus | Without Homology |
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Chinese hamster | Cricetulus griseus | Without Homology |
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Rabbit | Oryctolagus cuniculus | Without Homology |
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Pig | Sus scrofa | Without Homology |
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Cow | Bos taurus | Without Homology |
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Sheep | Ovis aries | Without Homology |
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Dolphin | Tursiops truncatus | Without Homology |
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Horse | Equus caballus | Without Homology |
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Dog | Canis familiaris | Without Homology |
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Panda | Ailuropoda melanoleuca | Without Homology |
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Cat | Felis catus | Without Homology |
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Pale spear-nosed bat | Phyllostomus discolor | Without Homology |
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Velvety free-tailed bat | Molossus molossus | Without Homology |
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Greater mouse-eared bat | Myotis myotis | Without Homology |
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Kuhl's pipistrelle | Pipistrellus kuhlii | Without Homology |
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Greater horseshoe bat | Rhinolophus ferrumequinum | Without Homology |
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Egyptian rousette | Rousettus aegyptiacus | Without Homology |
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Sloth | Choloepus didactylus | Without Homology |
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Tasmanian Devil | Sarcophilus harrisii | Without Homology |
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Opossum | Monodelphis domestica | Without Homology |
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Platypus | Ornithorhynchus anatinus | Without Homology |
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Chicken | Gallus gallus | Without Homology |
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Turkey | Meleagris gallopavo | Without Homology |
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Zebra Finch | Taeniopygia guttata | Without Homology |
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Budgerigar | Melopsittacus undulatus | Without Homology |
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Painted Turtle | Chrysemys picta | Without Homology |
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Lizard | Anolis Carolinensis | Without Homology |
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Frog | Xenopus tropicalis | Without Homology |
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Zebrafish | Danio rerio | Without Homology |
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Drosophila | Drosophila melanogaster | Without Homology |
>RPLP2P1 |
AGCAACACCTCCCTTAGTGCCAAGGACATTAAGAAGATCCTGGACAGAGTAGGCATGGAGGCAACTGATGACTGGCTAAACAAGGTTATCAGTGAGCTGAATGGAAAAAATATTGAAGATATCATTGCCCAAGGTATTGGTGAGCTTGCCAGTGTGCCTGCTGGTGGGGCTGTGGCCCTCTCTGCTTCTCTGGGCTCTGCAGGTCCTGCTGCTGGTTCTACCCCTGCTGCAGAAGAAAGATGACAAGAAGGAGGAGTC |
>NM_001004.4 |
CCTTTTCCTCCCTGTCGCCACCGAGGTCGCACGCGTGAGACTTCTccgccgcctccgccgcagacgccgccgcGATGCGCTACGTCGCCTCCTACCTGCTGGCTGCCCTAGGGGGCAACTCCTCCCCCAGCGCCAAGGACATCAAGAAGATCTTGGACAGCGTGGGTATCGAGGCGGACGACGACCGGCTCAACAAGGTTATCAGTGAGCTGAATGGAAAAAACATTGAAGACGTCATTGCCCAGGGTATTGGCAAGCTTGCCAGTGTACctgctggtggggctgtagccgtctctgctgccccaggctctgcagcccctgctgctggttctgcccctgctgcAGCAGAGGAGAAGAAAGATGAGAAGAAGGAGGAGTCTGAAGAGTCAGATGATGACATGGGATTTGGCCTTTTTGATTAAATTCCTGCTCCCCTGCAAATAAAGCCTTTTTACACATCTC |
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