Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name COX11P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:28446923-28449328  UCSC
Coordinates (T2T) chr6:28318364-28320768  UCSC
Coordinates (hg19) chr6:28414700-28417105  UCSC
Strand +
Parental Sequence XM_011524342.3
Parental seq. overlap 2228 bp
Parental seq. overlap (%) 26.8%
Genomic Region Intergenic
Retrocopy Summary COX11P1, located on chr6:28446923-28449328, is a retrocopy of the parental gene COX11. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name COX11
Full Name cytochrome c oxidase copper chaperone COX11
Also known as COX11P
Coordinate chr17:54951898-54968785
Strand -
Gene summary Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq, Jun 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes COX11P1
Bonobo Pan paniscus LOC100976343P1
Gorilla Gorilla gorilla LOC101154556P1
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>COX11P1
CATTTGACCTCTCGTCCCTGAGAGGCGGGTGGTTGTTAGTTCAGGGGGTTATGGGAGGGCTCTGGCATCCGGGATGGAGGCGCGTCGCTTTCTGTGGCTGGCGCTGGATCCACCCTGGGTCTCCAGCCACGGCTGCAGAGAGGGTAGCGCGGTTTCTTAGGCCAGAGTGGAGTGGGACAGGAGGTGCCCAGAGACGACTGTGGTGGCTTGAGACATGGAAGCGCTGCAGCCTTTGAGCCCAGTATCCAGCATTGCAGCCGCCGCGGCGGTCTAAGAGCTCAAACCCTTTCAGGCGCGCGCAGGAGGAGGAGCGGCGGGGGCGGCGGAACAAGACGACCCTCACTTAACGTGGCCGCTGTCGCCGTGGGCATGCTGGGGGCGTCCTACGCTGCCGTTCCCCTTTATCGGCTCTATTGCCAGACTACTGGACTTGGAGGATCAGCAGTTTCAGGTCATGCCTCAGACCAGATTGAAAACATGGTGCCTGTTAAGGATCGAATCATTAAAATTAACTTTGATGCAGATGTGCATGCAAGTCTTCAGTGGAACTTTAGACTTCAGCAAACAGAAATATATGTGGTGCCAGGAGACACTGCACTGGGGTTTTACAGAGCTAAGAATCCTGCTGACAAACCACTAATTGGAATTTCTACATACAATGTTGTTCCATTTGAAGCTGGACAGTATTTCAATAAAATACAGTGCTTCTGTTTTGAAGAACAATGAATTTGCTAAAGACCCAAGAATGATTAATGTTGATCTTATCACTCTTTCTTACACTTTTTTTGAAGCAAAGGAAGGGCACAATTTGCCAGTTCCAGGATATAACTGAAGTCAGCAACTAAGTCTTCCTTCAAAGTTGTGATTTTTGGGAAAATCATGTATCCTATCTTCTCAAAGGAGAAATATTGTACAATAATATGAAGACTTATATTTTAAATAATTATTTTTTCTCAACTAATTTATTTCACTTAAAATTGAGAGAACAAGTTCAGCTTTTATCATAACAAACCCACATGCCTAGCTAGAATATATGAGTGACTATTCAATACCATACTGAAGAGTTTGATAGCATTAAAATAAGCCGCTTTGTTTTTTAAATATGCAGGCATGGGTTCAGCTTAATTCTATAATTCCCTTCCAGATTATTAACTCTTCATACTTATAGCAAAGAATCTGACAATGTTTTTCAAAAATGAATGCTCAGGGTTATTTGTTTCAAGTCATAGGCCAGAACTTCTGACCATGTTTATTATGTCTAAAAGAGTTGGTTGCTATTTTCCTTCATTATAAACAGTCAGTATTTTAAAAGCTCAAAGTAGAAGAGGAGTCACCAAGCCCTAACAGCTTGTCCAAAGATTTAAATTCTTATTTCAAATTTGATTTGTCCTTTAAGATTTAGGGCTATTTTATATTCAGAGTTCTGAATAATTACTTTGAAATTGTAGTATCATGAAATTGAAATAAAATACATCTACTAGGCTGCTAGCCAAAGCATCATCATTACAAGTCCATGAATGCTAAAATGTACAAGTGGGATTGTGAAGATTTACTGACATCAAAAGTTCTTCTGGAAACAAACCTTTGTAAAAAAAAAAGTGTAAATTATTTTAATAGTGATTTATTTGTCATCAAATGTACAACTTATTCTGAATATTTTCATTTTCTGTGTTCCAAACAGAAATGTTAAGTTGCAGTAAAAAGAGAAAAAAAGACTATTTAGAATTACAAAGAATCATATTTAAAGGCTGCCCAATGTAGAGTCTAGTGACCTGTTCAGGACACCTGAAATATAATTAAATGACAACATCAAGGTTTTAACAATTTATAATTCCAAACCAGAGGATTATAAAGAAGTGCAAATTGACTTTTACATTCAACTTTAGTTAAATGAAGGCACTCAATATTCTTCCTGAATAATACATTCAGTTTCTCACATTTTATGTTTTCATCTGTTCCAATTATTTTGTAGTAAAATAATCTACTCTTATCACAGCTGTGTGACGATTTCTAAATGTAGGAAGGCCTGTGAAACATATGACACTGCAGTTAAATTTGTTGGCCTAAGGACTAAGTAATTTTTCTTCTGCTGAAGTTTTAAGTGAGTATTTGTTCCAAACAAGTTCTGTTGAAATCTCACGCTGTTGTCAGGAATCAATGTTATCCTGGAACTGTTATTCTTCTATTTAATCTTCATCATAGCAGAAATGCTCCACTGTGGCTTTGACATGTTGGTAGGTATTGTCTTCCAGGCTTCAAAGCTGCACAGAGTCTACCCTTTAGAGAATTGGCACCTTTGATGTGGCTAGTGAGCTGATCATCTACTTTCTTCT
>XM_011524342.3
AGATTTGACCTCTCGTCCCTGAGAGGCGGGTGGGTGTTAGTTCAGAGGGTTATGGGAGGGCTCTGGCGTCCTGGATGGAGGTGCGTTCCTTTCTGTGGCTGGCGCTGGATCCACCCTGGGTCTCCAACCAGGGCTGCAGAGAGGGTAGAGCCGTTTCTTAGGCCAGAGTGGAGTGGGACAGGAGGTGCCGAGAGAGGACTGAGGTGGCTTGGGACATGGAAGCGCTGCAGCCTTCGAGCCCGGCATCCAGCATTGCAGCCGCCGCGGCGGCCTAAGAGCTCGAACCCTTTCACACGCGCGCAGGAGGAGGAGCGGCGGCGGCAGAACAAGACGACCCTCACTTACGTGGCCGCTGTCGCCGTGGGCATGCTGGGGGCGTCCTACGCTGCCGTACCCCTTTATCGGCTCTATTGCCAGACTACTGGACTTGGAGGATCAGCAGTTGCAGGTCATGCCTCAGACAAGATTGAAAACATGGTGCCTGTTAAAGATCGAATCATTAAAATTAGCTTTAATGCAGATGTGCATGCAAGTCTCCAGTGGAACTTTAGACCTCAGCAAACAGAAATATATGTGGTGCCAGGAGAGACTGCACTGGCGTTTTACAGAGCTAAGAATCCTACTGACAAACCAGTAATTGGAATTTCTACATACAATATTGTTCCATTTGAAGCTGGACAGTATTTCAATAAAATACAGTGCTTCTGTTTTGAAGAACAAaggcttaatccccaagaggaagtagatatgccagtgtttttctacattgatccTGAATTTGCTGAAGATCCAAGAATGATTAAAGTTGATCTTATCACTCTTTCTTACACTTTTTTTGAAGCAAAGGAAGGGCACAAGTTGCCAGTTCCAGGATATAATTGAAGTCAGCAACTAAGTCTTCCTTCAAAGTTGTGATTTTTGGGAAAATCATATATCCTATCTTCTCAAAGGAGAAATATTGTACAATAATATGAAGGCTTATATTTTAAATAATTATTTTTTCTCAACTAATTTTTTTCACTTAAACTTGAGAGAACAAGTTCAGCTTTTATCATAAGAAACTCATATGCCTAGCTAGAATATATGACTGACTATTCAATACCATACTGAAGAGTTTGATACTATTAAAATAAGCCGCTTTGTTTTTTAAATATGCAGGCATGGGTTCAGCTTAATTCCATAATTCCCTTCCAGATTATTAACTCTTCATACTTACAGCAATGAATCTGACAATGTTTTTCAAAAATGTATGCTCAGGGTTATTTGTTTCAAGTCATAGGCCAGAACTTCTAACCATGTTTATTGTGTCTAAAAGAGTTGGTTGCTATTTTCCTTCATTATGAATAGTCAGTATTTTAAAAGCTCAAAGTAGAAGAGGAGTCACTAAGCCCTAACAGCTTGTCCAAAGATTTAAATTCTTATTTCAAATTTGATTTGTCCTTTAAGGTTTAGGGCTATTTTATATTCAGAGTTCTGAATAATTACTTTGAAACTGTAGTATCATAAAATTGAAATAAAATACATCTACTAGGCTGTTAGCCAAAGCATCACCATTACAAGTCCATGAATGTTAAAATGTACAGGTGGGATTGTGAAGATTTACTGACATCAAAAGTTCTTCTGGAAACAAACCTTTGTTAAAAAAAAAAAGTATTAAATTGTTTTAATAGTGATTTATTTGTCATCAAATGTACAACTTATTCTAAATATTTTCATTTTCTGTGTTCTAAATAGAAATATTAAGTTGCAGTAAAAAGAGAAAAAAAGGCTATTTAGCATTACAAAGAATCATATTTAAAGGCTGCCCAATGTAGAGTCTAGTGACCTGTTCAGGACACCTGAAATATAATTAAATGACAATTATCAAGGTTTTAACAATTTATAATTCTAAACCAGAGGATTATAAAGAAGTGCAAATTGACTTTTACATTCAACTTTAGTTAAATGAAGGCACTCAGTATTCTTCCTGAATAATACATTCAGTTTCTCACATTTTATGCTTTCATCTATTCAGAATTATTTCATAGTAAAATAATCTACTCTTATCACAGCTGTGTGACGATTTCTAAATGTAGGAAGGCCTGTGAAACATGACACTGCAGTTAAATTGGTTGGCCTAAGGACTAAGTAATTTTTCTTCTGCTGAAGTTTTAAGTGAGTATTTGTTCCAAACAAGTTCTGTTGAAATCTCACGCTGTTGTCAGGAATCAGTGTTATCCTGGAACTGTTATTCTATTTAATCTTCATTATAGCAGAAATGTGCCACCATGGCTTTGACATGTTGGTAGGTATTGTCTTCCAGGCTTCAAAGCTGCACAGAGTCTACGTTTTAGAGAGTTGGCACCTTTGATGTGGTAGTGAGCTGATCATCCACTTTCTTCTAAAATAAAGAGAAGAAAATGGCCAGTATTCATCCTGTCCTTCTCTTTCCCCATTCCTTGATAACTCTCTTGTCTTTACTGGGAAGCTGGAGAGTCACAGTCTAGTAGAAGAAAGggtcactgtcacccaggctggagtgcagtggtgcaatcatggcttattgcagcttcgacctcccaggttcaagtgatccttccacttcagcctctcaaaatgttgggattagaggcataagccaccatgccaggcCCATTCAATTCTTTATATGCGTCTTACATATGTCTGTAGCTGGAAAATATACCTGAAAGCACAACATTCATATATACAgtatagcaaaacatggctgaggaaaaatctcaaaaatcacagcgctatgaaaccatgatcaccaagttcataaggccccagaatggtgctacaattttaatgtttccctaaaaagtttggtctcatctccctcaaaacgatttcagtcttcttcactctcctcaaacctctaaactctctggtagaaactgcattcttaatacattaaatgtcttgatatggaaacttcctcattttcccatcactaaatcttcaagtttatcttcatttgtattgtccattatttctgtgatcctgtctattcctggcttctgaagcacttgacccattcagttattcttcccttcctgagtcttcaacctctccttctatgccagatcctattcttcaacattcacagattctccagcatctcccatgtctcccattttatacaaagtacagcctttaattccatctcttcttgtagtaaatgccttagtatcctctagctaccaacaaccccttttttttttttttttttgagatggagtttcactcttgttgcccacgctagagtgcaatagtgggatctcagctcactgcagcctctacctcctgggttcaaacgattctcctattcatcctcccgaatagttggaattacagacacccgctaccacgcctggctaatttttgtatttttagtagagacagggttttgccatgttggccaggctggtctcaaactcctgacttcaggcgatccgcctgccttggcctctcaaagtgctgggattataggcgtgagccaccgtgcccggccccaaacctgttttcatcactgcttcatatttaagttctaagaagttatctgtacttactgtctctacttaatctctcatgtgcttttcaaatgcactgaaatttgggttctgtcttcatcagtccatcaaagtagcttttactaaaatcatcaatgatctccaatccattatctagttttcagttcttatcttacttgtctgcccctggcactgttcttcacagttgtactcgctcctttttgcttccaaattacattttcctcatctggtactgagctccctgttaactttctttactcttggttttagcatttccatttccttgaatgtgccagagctctgtcctctgggtctttgtacaggttgttccttgggcctacaatactcatttccaaacttttcacttaactaagaattgcaggcctcagcattaatgctacctgaagctttctctaatcctcatttaaattagttctgttacaaactttcaagttgccatattctttcataacattaacacaaattttgtaaacatgtatttggtggtttgtctaatttctgtatccatactacgtttaacctctgtgaggacaagggagcatgtttcttgttcagaattataaattagtccagtcatagtccctggcacataataTTGAAATTAGTGAATCGTGTGTATCTTCATAAACATACTGTTTGTCCTGGTAGAGCAAAAATTGTCAACCTGGGATTCATGGACAACCAATGATGTGAAAAAAACCCAGTAATTTCCTGCAAGATTCTGTGCTTTTCCTTGGAGGGAAGTCCCTGAATTTCATGGGACTTTCAAAAGAACTGAGACATTCTGACCCCCAGAAAGAAAGACCCACCACAGTGATAAAAGAGTTCCAAAGCTTCACCTCCAGCTTTTTACTGTCTCTCCCACCGCCAGTATCTGTGACACTGCCGTATCAACATACAGCAATCTCCTAATTTGAATATAATCAAGAACTTTTCCACTACCTGTTTGGATGGAGAAACTGATTAAAAAAACGTTTCTAGAAAGCATACCTAGTTAAGTGCCAGTGTCTTAAACCACTAATATGATCAGTGATATATCTACTCTATCAGGCAGAATGACTTAGAGAAATTTCTCAAACCTGAGTTAGGAAAAAATACATAGTGGACTCCTAAGTCCCTTAACATCTGCTCATAAATTAAGTCAACCATTACATTGAGGGATTAAACCAGGGACCAGAATATCAAATGTCTACACATGTCAGCCAAAGAAGAGATGCAGAGGGTTGGGTGGGGCtggaagcagataggaggggtctccagggactataggagtacaatcaacttgagtaatcacctgcttttttccccaaaccctgtgtggaatgcagccagctagctggtttaaaccagttcatgacagacctcagcaatttacagatggatcccagtgtactttcctcattaccatgctagtatcttcaccctgggagatgctatagcttcattaccataacatgtgacctgtgtgctgaaataacgactcactgcatctgcacaactgcaacccctttccatgcaacgacataccctcttccctctctatcaccccataaaaccctcctgtcactttcctgctttggagactatgcccggtgctttatttgtgacaagtaataaaactattgctcaaagcctgcattcttggttggttatagtggctcatgcctataatcccagcactttggaaggctgaggcaggaggattgcttgagcccaggagttcaaaactagcctgggcaacacagacccccttctctataaaaaagaaaaaaattaaaaggctaggcacggtggcttacacctgtaatcccagcactttgggaggctgaggtgggtagatgaacttgagaccaagagttcgagaccagcctgggcaacgtggcaaaaccctgtctctactaaatatacaaaaaaattagccaggcgtggtggcacatgcttgtagtccccagctactcaggaggctgaggcatgagaattgcctgagcctgggaggcagaagttgcagtgagccgagatcacccccactatactccagcctaatgacagagtgacactctgtctcaaaaaattaaattagccaggcatggtagcacaccccaatagtctcagctactcatgaggctgagtagggaggactgcttcaacctgggaagtcaaggttgcagtaagccgtgatcatgccactttattctagtttgagtgacacagtgagaccctgtcaagaaaaaataataataacctgtgttctcatggagagttgtctattaccagatgaatgaatctcaggtttttttaggggtaacaAGTCTGGTACCCCAGATGAGACCCAGGGTTGAGCCCTGACTTGACCTCCCTTATAGGCTCCTGGCAGGCAAAGCAGTGGGATGTGGAAGCATGCGTGGGCCAACTCACCTCAGTTGCCAAGAAGGAGACTAGAGAAGGGCCTTGGGACCCCTGACCTGGTGTCTAGTGTAGTCCACTGACCAGCACCACAAGACCTCTCTGGGAGAGTAGAAGCGGCTGCCTAGAGCCCAGACCTTTTGCTCGGTGCTGCTTTGAAGCAGCAGCTCCATGAACTACTAAAAGAGTGGTCTGGGTTTTGATCATTAGGATTCTGGGTTGTCAGGATTAGGACCTAGGTCAAGGGATCCAGGATTGTTGAGAAAAAGAAGTTCCTTCTTTCAGGTCTGGGAGACTGAGAGACATCGCCATCGTTTTAACAAGGGGAATCCCCAACAAAAAGACAAGGATGCTTGTCTTCAGGCTTTGTTCCCTACGTGGTATAACTGTAGGGCTCAATATTCTTACTTGTCTGTGGCCTGAATGAATATGAAGTCTGGATTCTTCTACCCTTAGTCTGTGGCAACCCCTAAAATATCAGGCTTTGTTTTGCAGCAGTCACAGAAGGACTGCTGTTAGTTTGATGAGGAGACCCAAGTTTCAAAGGGGGCAGTTTTGGTGGGATCATGATCCCTGGAACCAGAATGCAGTGATACAAAGGTTACATGAACAGTGTGTGTGCTTTCTCTGAGGAAACACCTCACTCACTTGATTGATTTACCTACCTCCCCACCACCTGAGCTGGATCCAGAACTACTTCATTGTCTCCATGAGATCTCCTGGGAGGCTGCCCGGACCGAACATGATCCAGGGAAAGGAAATCCCTGTTATCCTCTCAGCTTCCCAGGACCTCTGGATGGCTTTGCATGGTGGCCAGCAAAGAGGACCAGAAGTATTCAAGCTGAGTTGTGGGATTTGTGTCATCATTAATCTCCAGAGTTTGGAAGCCCCTCAGACTGTGTGCAGAGACCGTAGAATGTCGTGAACTAGGTCTTGGAAGGAGAGCTTGTTAGGGTGCCtcctctggcaatggaaactgcatatccacccatgaccaaaaagcaaatgatatattactgtaatacagcctggctccagtattccctagatcagaagagatggtctgaatatgggtcacttactgcaactctccaattggactttttttgcaagaaacatggtaaatgggaagaaatgccctatatgcaatgttttatggccctctatcaaaaccctgccttgcagatgaaatgcagaatatgtAAATTGGCCAAAGGGAACTATATTGCCAATTCTAGAAGCCTCTGGAGAGGAAGCATCAGTCATGTGGGGGCCTATAGGGAAGGGAACAAGTAAGAAGAGTCCCTTTACTACCCCCTCCAAGAGAAGTGAGGCCCTCTAACTCTACTCGGGGACTGGAACCTTGGCCAATACAGGGGCATAGTCCACCTTCTTGGAAATGGTACCCTCTGCACCTCCAGGGAAAAGCAAGGGCCCGTTCTGTATTTGCCAGGCCCTCCAAACTCTGCAGAGCCAGCTGTGGCTCCTGCTATGGCAATAGCAGGCCCCTGTTGCACTCTTCTTTGCCAGGGAGCACCACTCATAGTGGGAACGCATATAACCCTGGAGGGTGACTGTTGCCACTCAGAGCATGCCTGTTGGAGAAAGAGGTTTTGCTCGGGTCTATGTGTTTTTTAAAACTGTTGACTTGTATAACTGGAAATCCCATAGTAAGGGCTTATGGGTGAGCCCACGAGAGTTCGTAACTCTCATATGGAGAATATTCTCCACACATAACCCTACCTGGCCAGGTGTGCAGACCGTAACAGCAACCCTGCTCACAGCAGAAGATAAATCTGCCACCATGGCCAAAACTAAGGAGGAGGCAGACAATATGTGTGCTGATAACCTGGTGACCTGGCCCGTTGAGGTGTCAGTCCCAATAGCCAACCCAAACTGGGACCCCAGTGATAACAAGAATCAAGAGTGGCTTCATCATTATAGGAATATGCTTCTCAGAGGTATGAGGGAAGCAAGCCAGTCCCTGGTCAATTGGGGAAATCTCAGAGAAATAGAACAAGGCCCTAATGAAAATCCATCAGCATTCCTAAATTGATAATAAGAATGCCTCCAGAATTACACCCCTTGGGACCCAGATGACCCAAAAGCTGAGTAGTACTTTAATCTCACTTCATCTCTCAGCCCCAGATATTCAGAGAAAACTCTAAAAAGTGGCAATAAATCCACATACTCCCCCTTTCCAACTGGTAGACATCTCCTTTAAGGTCTATAGTAAAGAGATGTGGCATCTGATGAAAAGGAAGACAAGAAGATGCGGCAGCCCTACAGACTACTTCAGGAAGCCCAGGAAGAAGATGGCATGGGTGAG

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