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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name BET1P3
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:28601888-28602093  UCSC
Coordinates (T2T) chr6:28473263-28473468  UCSC
Coordinates (hg19) chr6:28569665-28569870  UCSC
Strand +
Parental Sequence NM_005868.6
Parental seq. overlap 172 bp
Parental seq. overlap (%) 11.6%
Genomic Region Intragenic (SCAND3)
Retrocopy Summary BET1P3, located on chr6:28601888-28602093, is a retrocopy of the parental gene BET1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BET1
Full Name Bet1 golgi vesicular membrane trafficking protein
Also known as HBET1
Coordinate chr7:93993245-94004355
Strand -
Gene summary This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus BET1P2
Crab-eating macaque Macaca fascicularis BET1P3
Rhesus Macaca mulatta BET1P3
Baboon Papio anubis BET1P3
Golden snub-nosed monkey Rhinopithecus roxellana BET1P1
Chimpanzee Pan troglodytes Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BET1P3
ACCCTGGTGCTGAAGACATGATCTGGGTAACCCCTAGCTCTTTCCTACCCACCCACCCCTCTATGCCCTCCATTTCCCTCTCTCTTCTGACATAATGAAGCATGCAGGCCTGAGTGAAGGAGTACCTTCTGGCAGCTATGGGAACTATGGCTATGCTGATAGTGCAGATAATGCCTGTGAAGAAGAAAGAAAGACTCACTGAAAGT
>NM_005868.6
ACTGATGTCGTGGCGCTTTAGGGGAAGAAGTTGGTGTTTCGCTGGGCCCTGGTACTGAAGACGCGGTCCGGGTCGCCCCTAGCTGTTTCCTACTCACCCAAAGCCCCGCACCCGCCTTTTCTCTCTCTCCTCTGGCAGGATGAGGCGTGCAGGCCTGGGTGAAGGAGTACCTCCTGGCAACTATGGGAACTATGGCTATGCTAATAGTGGGTATAGTGCCTGTGAAGAAGAAAATGAGAGGCTCACTGAAAGTCTGAGAAGCAAAGTAACTGCTATAAAATCTCTTTCCATTGAAATAGGCCATGAAGTTAAAACCCAGAATAAATTATTAGCTGAAATGGATTCACAATTTGATTCCACAACTGGATTTCTAGGTAAAACTATGGGCAAACTGAAGATTTTATCCAGAGGGAGCCAAACAAAGCTGCTGTGCTATATGATGCTGTTTTCTTTATTTGTCTTTTTTATCATTTATTGGATTATTAAACTGAGGTGATGCATGTAATTGTGAATTTGGAATTTGTTCCAACTTAATGGCTTGCAGTACCACTTTGATAAAAATCAGCATCAAAACATTCCTAGTGTTCAAATACTGTGGCATTTTCCATTGAAAATTGCTGAATTTTGCTTATTTTATAAATCACATTAGTTAATACAGTGGTCTTTGAATACTGTTTCTTAATGACTCATTTTAGCCCCTATTTTCAGGGGTAGTGAGAGGGTGTGGCTCCACTAATTTCCAGTTTGTTTTTCTATTGTTTGCCAACTGTCAGATTAAATAGCATTATAATATTTTGTTGTAATCATAAATGCAGGTTTATGTCCCATGTAAGGAAACTTAGTGGGAGAGTAACAGAATGCCTGGAGAGCCTGACTCTGAGCTCTTGAAGTAGTCAGCCAGTTTGTGGTAAAATGGTAATTGAATTTTCCTAACTGCATCAACTGTAATGATATACTCCCTTCTCCTCCTTTATTTAGTTAAAATTGTAGGCTGATTTCTTTTTACCTACAATCTTCCTAATAATTTTTGATGATAATGACCCCTCATTTCTTTCTGCCCAAAGACCTCATTCTTTAAATAAAACTTGTTATTTTGGCATATTTCTGGTAGGGCCCATTGCACATGTGTATCAGTATAGTTATTATTTCATATTAACTTTATGAATTCTCTTGACTTGGCTTATAATAGTTTTATGATTTTTACTACATAGGTAGCACATTTATCATTTGTGACAGAATAATGTGAAGTTAAGTAATTACTGAACTTTAAATGGAAATAGTATGCAAGAAACTCAGGCATTGAACTTGAAGATAAGAGTATTATTGCTTTAATCCAGTGTATTTGTTTATGGAAAGAAAAACACAAAGGCAGACTGTTGAGTAAAAAATATTAAATATTGTTAAATATTCTGTATTTTGGAATTTATCCATTTATAGGCTTCAAAAGTAAATTTTTAAATAAAATATATTAGTCGACTGTG

Publications

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