Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CMPK1P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:35765897-35768052  UCSC
Coordinates (T2T) chr6:35586283-35588436  UCSC
Coordinates (hg19) chr6:35733674-35735829  UCSC
Strand +
Parental Sequence NM_016308.3
Parental seq. overlap 1618 bp
Parental seq. overlap (%) 54.4%
Genomic Region Intergenic
Retrocopy Summary CMPK1P1, located on chr6:35765897-35768052, is a retrocopy of the parental gene CMPK1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CMPK1
Full Name cytidine/uridine monophosphate kinase 1
Also known as CK|CMK|CMPK|UMK|UMP-CMPK|UMPK
Coordinate chr1:47333790-47378839
Strand +
Gene summary This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CMPK1P1
Bonobo Pan paniscus CMPK1P1
Gorilla Gorilla gorilla CMPK1P1
Orangutan Pongo abelii CMPK1P1
Gibbon Nomascus leucogenys CMPK1P3
Green monkey Chlorocebus sabaeus CMPK1P2
Crab-eating macaque Macaca fascicularis CMPK1P1
Rhesus Macaca mulatta CMPK1P1
Golden snub-nosed monkey Rhinopithecus roxellana CMPK1P1
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CMPK1P1
TCCGAGGTGCGGTGCAGGCTGAGCCACTGCCTGAGCCGCTGCTCCACGTCCTGGGCCTTAGCTTCCCGCTGCAGACCTGCCGGCCGATTCTTCGCTGCCCTCCCGGTCTCATGAAGCCGCTGGTCGTGTTTGTCCACGGCGGTCCCGGCGCGCTGGCATCCTTGAGAAAGATGGCTACACACACCTTTCTGCAGGAGAGTTACTTCATGATGAAAGGAAGAGCCCAGATTCACAGTATGGTGAACTCACTGAAAATTACATTAAAGAAGGAAACATGGGACCAGTGGAGATAACCATCAGTTTATTAAAGAGGGAAATGGATCAGACAATGGCTGTCAGTGCTCAAAAGAGTACATCTTTGATCGATGGATGGGTTTCCAAGAAATCAAGACAACCTTCAAGGTTGGAACAACGagGTTGAATGGGAAGGCAGATAGATGTATCTTTCATTCTGTGTGTGTGTGGTTTTTTAACTGTAATAATAAGATCTGTATTGAATGATGTCCTGAGAGAGGAAAGAGTAGCGGTAGGAGTGATGACAACAGAGAGAGCTTGAGAAAGAGAATTGAGACCCATCTTCAGTCAACAAAGCCAATTATTGACTTATATAAAGAAATGGGGGAAAGTCAAGAAAATAAATGTTTCCCAATCTGTTGATTAAGTTTTTGAAGTTGTGAAGATTTTTGACAGGAAAACTAATTCGAAACCTGAAAGCATCCTTGAAATCTTGCTTGAATACTGCTTTGATAGCTGCTATCGCGACCCCTTTTTAAGGCAATTTTAATCTTTCAAACTACATCTCACCTAGTGGCTGGAAAGTATAGGTAAGACAAATTAAGTTTTTTATGTACTTTTTTTTCGTCACAGAAGAGAGTTAATTAAGAGACATAACTTCATCTTAGTTATGGTGCTCACTAAACAAAGAAGCGTATCAAGCTATTTTTTTTTATTCAAAAAGACTATTCCTTTCATAGTTTGTGCCTTCTATGAGCAAAACTTTTTCGTATGTGTGTATGTCCCTTTAGTAATTACAACATGTTAGGATTTAGGGATACCCACTTCCTCCTTTTCTTGCAAGTTTTAAATTTCCAACCTTAAGTGAATTTGTGGACCAGATTTCAAAGGAACTTTTTGTGGAGTCAGTTCTTGCACAATGTGTTTAGTAAACAAACTCAAAGTGGATTCTTAGCAGTGTTTTAATATATATCAAATAACTAACAATTTCCTATAGAAAAGTAAGAAAACATAGGCTTTGTTTTACTACAACTTGAACAATGTTGTATGACAGGGCATATTCTTTGCTTCCAAGGTTTGGGTTGGAAGCACTAGAGGTTCAGAGCCTGGCAGAACTGTCAGCTTTATTCTGACATAATCTAAGGGTATGGGGCAAGGATCACATCTAATACTTGTGTTCCTCATCCTCTATTATATGGTGTTATTCATGATTCAACTGATCTTAACAAAATTCCTAGCAGTGGAACCTTGAAATGCATGTGACTAGATTTATGCTAAAATGATTCAGTTAGCATTTTAGTAACACTTCAAATGATTTTTTGTTCATTTTCTAGACCAAATACAAGGTTAGGATTAATTAGAAGAAGCAATCTAGTTAAATTTCCCATTTGTATTTTATTTTCTTGAATACTTTTTTTTATAGTTGTTTAAAAAAATTTTTAAATCATTGCACTTTGGTCAGAAAAATAATAAATATATTTTATAAATGTTTGATTCCTTTCCTTGCTATTTGTATTCAGTAAATTATTGTTTTGGCATCATGTTGAAGCACTGAAAGACGAATAATCTTTAAAAGGCT
>NM_016308.3
CCCTTCCGACAGGGCCGCGGACGCCCGGGCAGCCACGGCGGCGGGGCCGCGGCGGGCGCCGGCTCAGCCCGCCCCTTTCTcccgccgcctccccgccccgccccgcgccgcgccggccGCTGTCAGCTCCCTCAGCGTCCGGCCGAGGCGCGGTGTATGCTGAGCCGCTGCCGCAGCGGGCTGCTCCACGTCCTGGGCCTTAGCTTCCTGCTGCAGACCCGCCGGCCGATTCTCCTCTGCTCTCCACGTCTCATGAAGCCGCTGGTCGTGTTCGTCCTCGGCGGCCCCGGCGCCGGCAAGGGGACCCAGTGCGCCCGCATCGTCGAGAAATATGGCTACACACACCTTTCTGCAGGAGAGCTGCTTCGTGATGAAAGGAAGAACCCAGATTCACAGTATGGTGAACTTATTGAAAAGTACATTAAAGAAGGAAAGATTGTACCAGTTGAGATAACCATCAGTTTATTAAAGAGGGAAATGGATCAGACAATGGCTGCCAATGCTCAGAAGAATAAATTCTTGATTGATGGGTTTCCAAGAAATCAAGACAACCTTCAAGGATGGAACAAGACCATGGATGGGAAGGCAGATGTATCTTTCGTTCTCTTTTTTGACTGTAATAATGAGATTTGTATTGAACGATGTCTTGAGAGGGGAAAGAGTAGTGGTAGGAGTGATGACAACAGAGAGAGCTTGGAAAAGAGAATTCAGACCTACCTTCAGTCAACAAAGCCAATTATTGACTTATATGAAGAAATGGGGAAAGTCAAGAAAATAGATGCTTCTAAATCTGTTGATGAAGTTTTTGATGAAGTTGTGCAGATTTTTGACAAGGAAGGCTAATTCTAAACCTGAAGGCATCCTTGAAATCATGCTTGAATATTGCTTTGATAGCTGCTATCATGACCCCTTTTTAAGGCAATTCTAATCTTTCATAACTACATCTCAATTAGTGGCTGGAAAGTACATGGTAAAACAAAGTAAATTTTTTTATGTTCTTTTTTTTGGTCACAGGAGTAGACAGTGAATTCAGGTTTAACTTCACCTTAGTTATGGTGCTCACCAAACGAAGGGTATCAGCTATTTTTTTTAAAATTCAAAAAGAATATCCCTTTTATAGTTTGTGCCTTCTGTGAGCAAAACTTTTTAGTACGCGTATATATCCCTCTAGTAATCACAACATTTTAGGATTTAGGGATACCCGCTTCCTCTTTTTCTTGCAAGTTTTAAATTTCCAACCTTAAGTGAATTTGTGGACCAAATTTCAAAGGAACTTTTTGTGTAGTCAGTTCTTGCACAATGTGTTTGGTAAACAAACTCAAAATGGATTCTTAGGAGCATTTTAGTGTTTATTAAATAACTGACCATTTGCTGTAGAAAGATGAGAAAACTTAAGCTTTGTTTTACTACAACTTGTACAAAGTTGTATGACAGGGCATATTCTTTGCTTCCAAGATTTGGGTTGGGGGCACTAGGGGTTCAGAGCCTGGCAGAATTGTCAGCTTTAGTCTGACATAATCTAAGGGTATGGGGCAAGGATCACATCTAATGCTTGTGTTCCTTATACTCTATTATATAGTGTTATTCATGATTCAGCTGATCTTAACAAAATTCGTAGCAGTGGAACCTTGAAATGCATGTGGCTAGATTTATGCTAAAATGATTCTCAGTTAGCATTTTAGTAACACTTCAAAGGTTTTTTTTTGTTTGTTTTCTAGACTTAATAAAAGCTTAGGATTAATTAGAAGAAGCAATCTAGTTAAATTTCCCATTTGTATTTTATTTTCTTGAATACTTTTTTCATAGTTATTTGTTTAAAAAGATTTAAAAATCATTGCACTTTGGTCAGAAAAATAATAAATATATCTTATAAATGTTTGATTCCCTTCCTTGCTATTTTTATTCAGTAGATTTTTGTTTGGCATCATGTTGAAGCACCGAAAGATAAATGATTTTTAAAAGGCTATAGAGTCCAAAGGAATATTCTTTTACACCAATTCTTCCTTTAAAAATCTCTGAGGAATTTGTTTTCGCCTTACTTTTTTTTCTTCTGTCACAATGCTAAGTGGTATCCGAGGTTCTTAATATGAGATTTAAAATCTTAAAATGTTTCTTATTTTCAGCACTTACATCATTTGGTACACAGGGTCAAATAGGGCAAATAATTTTGTCTTTGTATAATAGATTTGATATTTAAAGTCACTGGAAATAGGACAAGTTAATGGATGTTTTTATATTTTAATAGAATCATTTATTTCTATGTGTTATGAAATTCACTTAATGATAAATTTTTCAACATACTTGCCATTAGAAAACAAAGTATTGCTAAGTACTATAACATATTGGCCACTAAAATTCATATTGAGATTATCTTGGTTTCTTGGAAGAGATAGGAATGAGTTCTTATCTAGTGTTGCAGGCCAGCAAATACAGAGGTGGTTTAATCAAACAGCTCTAGTATGAAGCAAGAGTAAAGACTAAGGTTTCGAGAGCATTCCTACTCACATAAGTGAAGAAATCTGTCAGATAGGAATCTAAATATTTATAGTGAGATTGTGAAAGCAACCTTAAAGTTTTGAAGAAGACTGATGAGACTAGGTGCTTTGCTTCCTTTCATCAGGTATCTTTCTGTGGCATTTGAGAACAGAAACCAAGAAACATGGTAATTACTAAATTATGAGGCTTTGCTTTTTGTTTGCTTTTAAGTAGAAAAACATGTTGGCAACATTGAGTTTTGGAGTTGATTGAGATAATATGACTTAACTAGTTTTGTCATTCCATTTGTTAAAGATACAGTCACCAAGAATGTTTTGAGTTTTTTGAAAGACCCCAATTTAAGCCTTGCTTATTTTTAAATTATTTCCATTCAGTGATGTTGGATGTATATCAGTTATTTAGTAAATAATCTCAATAAATTTTGTGCTGTGGCCTTTGCTA

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