Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RBM22P4
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:45097958-45099349  UCSC
Coordinates (T2T) chr6:44932731-44934122  UCSC
Coordinates (hg19) chr6:45065695-45067086  UCSC
Strand +
Parental Sequence NM_018047.3
Parental seq. overlap 1161 bp
Parental seq. overlap (%) 50%
Genomic Region Intragenic (SUPT3H)
Retrocopy Summary RBM22P4, located on chr6:45097958-45099349, is a retrocopy of the parental gene RBM22. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RBM22
Full Name RNA binding motif protein 22
Also known as Cwc2|ZC3H16|fSAP47
Coordinate chr5:150690792-150701062
Strand -
Gene summary This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RBM22P1
Bonobo Pan paniscus RBM22P1
Gorilla Gorilla gorilla RBM22P1
Orangutan Pongo abelii RBM22P1
Gibbon Nomascus leucogenys RBM22P5
Green monkey Chlorocebus sabaeus RBM22P4
Crab-eating macaque Macaca fascicularis RBM22P1
Rhesus Macaca mulatta RBM22P1
Baboon Papio anubis RBM22P1
Golden snub-nosed monkey Rhinopithecus roxellana RBM22P1
Marmoset Callithrix jacchus RBM22P2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RBM22P4
AGGATTGTGGCGGTCCTCTCTCCCACCTCAACAGCTACCACTGCCTCCAGATGCTCTAAAGATGGCGAGCTCTCTGGGTTCCCAAGCTTACAACACCCAGAACTGGGAGGGGGTGGACTTTCCTGTTCTGTGCCAGGAATGTCTTGCAGAAATCTATATATATTAAATAGCCAAAGAAAAAAGCAGGAAGGAACGCAAAATTTGTGCCAGGCCATTCAGTGTTTTGCTTGTGCCCTGGGGTCCACATGCATTTCAAGAAGACAGAAGTGTGCCAACCCTGCAGTAAATTGAAGCATGTCTGTTAGGCCTAAATCTTAAGACCTAAAGCATGGTCTGCCCATCCAGGTTAATAATGCAGAACTGTCTTCTGAAGGTGACCTGCCAAAGTCTGATGTCAAAAAAAGAGTACTGCATGTAGAATATGAGAGACAGGGATTTCTAGCTCTGATGGAACGTGGCCAGTTTGCCTGCTGGGGAAAAAGCCACACTGACCAGAGACATGCTACTCAGTCCAGCTTGGACCACACCCTCCTACCAAAGGAGTAAGCCCCACATTTGCTCCTCCTGGGTGAAAGGAGAGTATAAGAGAGGAGAGGAACATCCATGCAGACATGAGAAGCCTATAGATCCAGATGATCCCCTTGCCAATCAGAATATTATGGAATCAATGATCCAGAAACAGATAAGCATCTAAAGTGGGCTTCAATCATGCCCCATCTGGACCCATCAGAGGACAAGGTTATCCTCCCCATATGTTGGTAGTCTGGATAATACCCTTTCTGAGACAGATCTAAGACATCATCACTACCAGTTTGGAGAGATGCAGATTGATTACTGTTGTTCAGAGAGAGCAGTGTGCTTTCATCCAGGTTTCCACAGGGCAGGCTGCAGAAGTGGCTGCTGAGAAGTCCTTTGATAAGTTGATTGTCAATGGCTGTAGACTCAACATAAAATGGGGAAGATCCCAAGCATCCAGAGGAAAAGAAAAAGAGAAGAACAGATCACAGACTCTGGGATCCAGCTACAGCCTATTCCAGCACTGCCATGAGCTCTTCCTCCTCCTACAGCAGCAGAAGATGCATGTGCCAGCTACTTCAACCTGCCCCAACATGGTCCTCCAGCTGTGGTGAACATTGCCCAGCCACCAGCCCCTAGTCTTCCACACCCCCAACCCCAGGATTTAGGCCACACATATTCACCTCAATGGGACCACCCTTTCCTTTCATGACAACTCCAGGATTAATCCACTATCTTTCTCATGACCCTCAGAGGATGGGAGCTCATGCCAGAAAACATAGGAAACCCTAGCACACTATCAACACTCTGGGGCTCTATGGAAGAAAGAACACTTAAAAATCCGAATCAATGAATCTTGGAATAAATGTGTTTTTC
>NM_018047.3
AGCCTCGGGGCTTGACGGGATTGTGGCGGTCCTCTCTCCCAATTCGGAAGCTACAGCTACCTCCGGACGCTCTCAAGATGGCGACCTCTCTGGGTTCCAACACCTACAACAGGCAGAACTGGGAGGATGCGGACTTCCCCATTCTGTGCCAGACATGTCTTGGAGAAAACCCATATATCCGAATGACCAAAGAAAAGTATGGGAAGGAATGCAAAATCTGTGCCAGGCCATTCACAGTGTTTCGCTGGTGCCCTGGAGTCCGCATGCGTTTCAAGAAGACTGAAGTGTGCCAAACCTGCAGTAAATTGAAGAATGTCTGTCAGACCTGCCTCTTAGACCTAGAGTATGGCCTGCCCATCCAGGTTCGTGACGCAGGATTGTCTTTTAAAGATGACATGCCAAAGTCAGATGTCAACAAAGAGTACTATACACAGAATATGGAGAGAGAGATTTCTAACTCTGATGGAACACGGCCAGTTGGCATGCTGGGGAAAGCCACATCTACCAGTGACATGCTGCTCAAACTGGCCCGGACCACACCCTACTACAAAAGGAATCGACCCCACATTTGCTCCTTCTGGGTGAAAGGAGAGTGTAAGAGAGGAGAGGAATGTCCATACAGACATGAGAAGCCTACAGATCCAGATGACCCCCTTGCTGATCAGAATATTAAAGACCGTTATTACGGAATCAATGATCCTGTAGCTGACAAGCTTCTAAAGCGGGCTTCAACAATGCCTCGGCTGGACCCACCAGAGGATAAAACTATCACCACACTATATGTTGGTGGTCTAGGTGATACCATTACTGAGACAGATTTAAGAAATCATTTCTACCAGTTCGGAGAGATCCGGACGATCACTGTTGTGCAGAGACAGCAGTGTGCTTTCATCCAGTTTGCCACACGGCAGGCTGCAGAAGTGGCTGCTGAGAAGTCCTTTAATAAGTTGATTGTAAATGGCCGCAGACTGAATGTGAAATGGGGAAGATCCCAGGCAGCCAGAGGAAAAGAAAAAGAGAAAGATGGAACTACAGACTCTGGGATCAAACTAGAACCTGTTCCAGGATTGCCAGGAGctcttcctcctcctcctGCAGCAGAAGAAGAAGCCTCTGCCAACTACTTCAACTTGCCCCCAAGTGGTCCTCCAGCTGTGGTGAACATTGCTCTGCCACCGCCCCCTGGCATTGCTCCACCCCCACCCCCAGGTTTTGGGCCACACATGTTCCACCCAATGGGACCACCCCCTCCTTTCATGCGGGCTCCAGGACCAATCCACTATCCTTCTCAGGACCCTCAGAGGATGGGAGCTCATGCTGGAAAACACAGCAGCCCCTAGCACCTTGTCACCACTCTGGGGCTCTGTGGAAGAAAGGGCACTTAAAACTCCCAGTAAATCTTGGAATAAATATATTTTTCCTTCCCTTGTAGTTTCCATGGTAGCTGAATGTGCTCAGATGTGAGCAGTCAGAGACTGACAGCCATGCTTTCCTATACTTGTTCAAAGGATCGATGGACCGTAAATAAGCTGCCATTAACACATCTGGTTACTGCTGTAACATGACTAATAAAACCGAACGCCTGTTCCCCTTACCCGTGTGGGGGACACGCAGATGAGTGAATTGGAATGTCCAGCAGAGTTACCCTCCCAATTATATGTTCATTTTGTATATTTTTTGGTCGGGGGAAAAATTGACCTGCAGTAAAAAAACCTTTGACCATTTTTATGTCCATTGGATACTTTCCTTTTTATCATCTTAAAAAAAGATAACTAGTACTAATCATTGTAGTGGCCTAAGTGTGATTTAACTCTTGAAGTCACACCCTCCGAAAGATGAGTAGAAACCAGCACCAGCACAGCCCAGATCTTCTCTTTCCTCTCCTTTTCCTCATTTATTCCTAAAGGAATCTGACCATTTTACGTCTCTACGGCCCAAAAAAAGACAAAAATAAAAATTCCTTTTTATTCCTGTCAACTGGATGGAAACACAAATTTCATGGAGCTGTGTACCATCGAAGAAACCTGGTGTCTGGCATGAAATTACTGTAAAGAACTTCCTGTAAAACACGTTCTTTAACAAACTGAAATGAAAAGCATTGGAGCGTCTGAATGAAAGACGTGACCTCCTGCTGGGACTCTGATGGTCTTCAGCATTCACCTTCGTGTGTCTTCAGTGTCTCATTGTCATCCCTGCTTCTGTTTGGTCTTAGAGTGTTTGGATATAACTGAATTGTAGATGGTAAAGGAAATTTGATGTGTTTTTTGTTTTTAAATAATTAAAACGGGTCAATTTTTCA

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