Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TFB2MP1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:5065320-5067009  UCSC
Coordinates (T2T) chr6:4934535-4936224  UCSC
Coordinates (hg19) chr6:5065554-5067243  UCSC
Strand -
Parental Sequence NM_022366.3
Parental seq. overlap 1501 bp
Parental seq. overlap (%) 83.7%
Genomic Region Intragenic (LYRM4)
Retrocopy Summary TFB2MP1, located on chr6:5065320-5067009, is a retrocopy of the parental gene TFB2M. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TFB2M
Full Name transcription factor B2, mitochondrial
Also known as Hkp1|mtTFB2
Coordinate chr1:246540561-246566261
Strand -
Gene summary Enables mitochondrial transcription factor activity. Involved in transcription initiation from mitochondrial promoter. Located in mitochondrial nucleoid. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TFB2MP1
Bonobo Pan paniscus TFB2MP1
Gorilla Gorilla gorilla TFB2MP1
Orangutan Pongo abelii TFB2MP1
Gibbon Nomascus leucogenys TFB2MP1
Green monkey Chlorocebus sabaeus TFB2MP1
Crab-eating macaque Macaca fascicularis TFB2MP1
Rhesus Macaca mulatta TFB2MP1
Baboon Papio anubis TFB2MP1
Golden snub-nosed monkey Rhinopithecus roxellana TFB2MP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TFB2MP1
AAACTTGGAGCGGGCCTGAGAGACAAAGACATGTGGATCCCAGTGGCCGGATTTCCTCCTCGGCTGAGGCTCTCCGCCTTGGGGGGCGCTGGTCGCTTTTGCATTTTAGGGTCTGGAGCGGCGATGCGAAAGCACTTGCCGGCGAGGAACCGCCGTGGCCTGTCTGACTCCTCTCCGCAGCTGTGGCCGGATCCGGATTTCAGGAACTCACCAAGGAGGGTGTTAAACTCCATCTTAGACTTTAAGCGTTACGTAACCAATCGGAGATTGGCTGAGACCCTGGCGCAAATCGTATGGAGAAAACAAAATAGACCTCCACACCTATTGCTGCAGTGCAGTCCAGGTCCTGGAATCCTGACTCAGGCATTACTTGAAATTGGTGCCAAAGTGGTTGCCCTTGAAAGTGACAAAACTTTTATTCCACATTTGGAGTCCTTAGGAAAAAATCTGGATGGAAAACTACAAGTGATTCACTGTGACTTCTTTAAAATAGATCCTAGAAGTGGTGGAGTAATAAAACCACCCGCTATGGCTTCTCAAGGGCTCTTTCAGAATTTGGGAATAGAAGCAGTTCCTTGGACAGCAGGCAGCCCTTTAAAAGTAACTAGAATGTTCTCAAGTAGAGGTGAAAAAAGGGCCACTTTGGAAACCTGCATATGACGTATTCCTGTACTTCTAGATATAAATTTGGACGAATAGAACTAAATATGTTTATTGGTAAAAAAGAATTCCAGAAACTAACGGCAGATCCCCGAAATCCAGACTTGTATCATGTATGAAGTGTTATCTGGCAAGTAGCTTGTGAGATTAAGGTTCTGCACATGGAGGCTTGGTCGTCATTTGATGTATACACCCAAAATGGGCGGCTGGAAAACCCAAAGTGTAGGGAATTATTGGAGCTATTACAACAAAATCTGTATCTTACTCGAATGACTCCTCATGGAAATTTATTTACCGAGAACTTAACACCTATTAACTGTAATATATTTTTTCACATGTGAAAGCACTGTTTTGGGAGGTGCAGTGCCAATCTAATAGACCACTTAAGTTCACTGACTCCACTTGGTGCAATGGATATATTGATGCAAATAGGAAAAAAGGAAGAAGAGAAAATAACTAACATGTACCCTCAAGACTTCAAAAAACTTTTTGAAACTATAGTGTTCCAAAGATTGTGCTTATAAATGGCTATATGATGAAACCCTGGTAAATATGTAGCAACTAGACTGTCGTTTTTGGTGGAGCAGTTTATTTATTTGGAAACCATGACATGAAAACCAAATTTGAAAGCTCACATCCTTTCAGCAGAAGATAACTGTTCTTGTTTTGCACATGACACGTAGATCATTTCTCCTGAAGTTGATATCATTGGCATATTGGATGAAACAGTGGCTGCTATTTTATTCACAATTGAATAAAGTGAAAACTTCAATTAATTGTGGATTTGATCAGATTGAATTCCTTTTGTTTCAGATTCCTATTTAAATATTTCACTTTCACTGTTGCTGATTTTTGCATCTTCTTGAGGAGCAAGAGTCTGTACATTATTAAGCTTAGAAAGTAAACAAAACTGATTTACTGATTTGTTTTGCATTTCAGTTTGTTGAAATGTATTGTCAAGTACTACAGAATGAAATTGt
>NM_022366.3
AGTGTTTACTTCCGCTTGACCTGGCCCGGACGCCAGAAAATGTTCCACGTGGGATACCCTGCGTGGGGTTCACTGTAGTAGCTGCACTAGGTGATTCTTGGAGCGGGCCTGAGAGACAAGGACATGTGGATCCCAGTGGTCGGGCTTCCTCGGCGGCTGAGGCTCTCCGCCTTGGCGGGCGCTGGTCGCTTTTGCATTTTAGGGTCTGAAGCGGCGACGCGAAAGCATTTGCCGGCGAGGAACCACTGTGGGCTCTCTGACTCCTCTCCGCAGCTGTGGCCCGAACCGGATTTCAGGAATCCGCCAAGGAAGGCGTCTAAGGCCAGCTTAGACTTTAAGCGTTACGTAACCGATCGGAGATTGGCTGAGACCCTGGCGCAAATCTATTTGGGAAAACCAAGTAGACCTCCACACCTACTGCTGGAGTGCAATCCAGGTCCTGGAATCCTGACTCAGGCATTACTTGAAGCTGGTGCCAAAGTGGTTGCGCTCGAAAGTGACAAAACTTTTATTCCACATTTGGAGTCCTTAGGAAAAAATCTGGATGGAAAACTACGAGTGATTCACTGTGACTTCTTTAAACTAGATCCTAGAAGTGGTGGAGTAATAAAACCACCTGCTATGTCTTCTCGAGGGCTCTTTAAGAATTTGGGAATAGAAGCAGTTCCTTGGACAGCAGACATCCCTTTAAAAGTAGTTGGAATGTTCCCAAGTAGAGGTGAGAAAAGGGCACTTTGGAAACTCGCATATGACTTGTATTCCTGTACTTCTATATATAAATTTGGACGAATAGAAGTAAATATGTTTATTGGTGAAAAAGAATTCCAGAAACTAATGGCAGATCCCGGAAATCCAGACTTGTATCATGTATTAAGTGTTATCTGGCAATTAGCTTGTGAGATTAAGGTTCTGCACATGGAGCCTTGGTCATCATTTGATATATACACCCGGAAAGGGCCGCTGGAAAACCCAAAGCGTAGGGAATTATTAGACCAATTACAACAAAAGCTGTATCTTATTCAAATGATTCCTCGTCAAAATTTATTTACCAAGAACTTAACACCTATGAACTATAATATATTTTTTCACTTGTTAAAGCACTGTTTTGGGAGGCGCAGCGCCACTGTAATAGACCACTTACGTTCATTGACTCCACTTGATGCGAGAGATATATTGATGCAAATAGGAAAACAGGAGGATGAGAAAGTAGTTAACATGCACCCTCAAGACTTCAAAACACTTTTTGAAACTATAGAGCGTTCCAAAGATTGTGCTTATAAATGGCTGTATGATGAAACCCTGGAAGATAGGTAGCAACTAGACTGTCGTTTTTGGTGGAGCGGTTCATTTATTTGGAAACTATGACATGAAAACCAAATTTGAAAACTCACATCCTTTCAGCAGAAGGTAACTGTTCTTGTCTTGCACAAGCCAGGCAGATCATTTCTCCTAAGCTGATATCATTGGCTTATTGGATGAAACAGTGTCTGCTATTTTATTCACAATTGAATAAAATGAAAACTTCAATTAATTGTGGATTTGATCAGATTGAATTCGTTTTGTTTCAGATTCCTATTTAAATATTTCACTTGTACTGTTGCTGATTTTTGCATCTTCTTGAAGAGCAAGAGTCTGTACATTATTAAGCTTAGAAAGTAAGCAAAACTGATTTACTGGTTTGCCTTTCAGTTTGTTGAAATGTATTGTCAAGTACTGTACAATGAAATTGTTTAAATTTTAATATGATTTAAGCTTTTTAGAAATTAAAATATTTTAAATAAGAA

Publications

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