Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name TNPO3P2
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:50897304-50898240  UCSC
Coordinates (T2T) chr6:50740068-50741004  UCSC
Coordinates (hg19) chr6:50865017-50865953  UCSC
Strand -
Parental Sequence NM_001382221.1
Parental seq. overlap 827 bp
Parental seq. overlap (%) 19.6%
Genomic Region Intergenic
Retrocopy Summary TNPO3P2, located on chr6:50897304-50898240, is a retrocopy of the parental gene TNPO3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TNPO3
Full Name transportin 3
Also known as IPO12|LGMD1F|LGMDD2|MTR10A|TRN-SR|TRN-SR2|TRNSR
Coordinate chr7:128954185-129055111
Strand -
Gene summary The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Several protein-coding and non-coding transcript variants have been found for this gene. [provided by RefSeq, Apr 2020]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TNPO3P1
Bonobo Pan paniscus TNPO3P1
Gorilla Gorilla gorilla TNPO3P1
Orangutan Pongo abelii TNPO3P1
Green monkey Chlorocebus sabaeus TNPO3P1
Crab-eating macaque Macaca fascicularis TNPO3P1
Rhesus Macaca mulatta TNPO3P1
Baboon Papio anubis TNPO3P1
Golden snub-nosed monkey Rhinopithecus roxellana TNPO3P1
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TNPO3P2
CAGGAACTACTAGACATGTCCAGGCACTATGCATCCCCACCTTTCAGCTCCTAGAACAGCAGAATGGTCTCCAGAGTCACCCTGACACTGTAGATGACATGTTCAGCCTGGATAGCTACCAGGTTTATTTAGTGTAGCCCTGTCATCTTGCTGAAGAGCCAAGTAATCATCCTTATATCACAGTGGGCCATTGCCTCTACTACCCTGGACCACTGGGATGCCAACTGTAGTGTCATGAGTTTCCCACCAGACCTCATCCATACAGGGGTAGCCAATGACCATGGGGAAGACTTTGATTTACAGAAAGAACTGATTGGGCAGGTGATGAACCAGCTTAGACAGTAACTTGTCAGCCAGTTGCTCCACACATGCTGCTTTTGTCTCCTCCCCAACATACCCTACCCAATGTGGCTAAAGTGCTCTAGGAGGTCATGCAGGTTGAAAGTCCAATTTTTTTTTGTCAATGGTTAGAGAATTCCTTGAAAGGACTGCCAAAGGAGACAACCATGGGAGCCCAGCACAGTGACACACAAACAACTTACAGACTTCCACATGCAAGTAACTGGTGCTGAGGAACGTAAGCAATTTGCTGGACCTTGCAAGACTTCACCAGGTTCTTTCAACAGCTCACACTCCTGCACTGTACCTGTCACCCAGGGATGTCTTTTAAATTAGAAGACAGGAAGAAAACAAAAAACCAGACTGTGTCCCACAATCAGAAACCTCCAATGTGGCAGAGAGGCCTTCACCACCAGCAGGCTGTATGGCCAGGCATGGAGAGACTCCAGCTTTCTGAGACCATCCTGAGGAGATCCTGTTTGGGGTGTGAGGGAAAATCAGAGCAGTTTAAAGAAAGATGACTGCAGCCTGCCCAGTGTGGTGGGAGGGGAGCTGGTTTCTTGGTAAACTTGTTTCTAAAAGGAAAAATAATTTTAAT
>NM_001382221.1
AAACGAACCTTAGGTACACTGGTGTGTGGCCTCCCAAGATAGGCTTCTGAGGGCAAGTCAGCGACTGAAGACGGGAGCGCCAGAATCTGTGGACTCAAGAGTCTAGAATCAAGTGGAAAAACCGGAAAAAAGGCCAGGAACCTGAATACGACCTAATAGCTGTTTCCGAGGGGGCAACTTCCACGGAGAGCCTTCTGCCCTGGTAACGGCCAAAGAGGAGGAGATGGCGCCAGTCAGGGAGCGGCCGTGGCCCAGACAGTGAGGAAGCGCGAAGGCGGAGCAACCGAGGAATCCTCCGGAGAAGAATCAGAGCCGTCGCTACCGCCACTACCGCCACCACCATGGAAGGAGCAAAGCCGACATTGCAGCTCGTGTACCAGGCAGTGCAGGCGCTTTACCACGACCCAGATCCCAGCGGAAAGGAGCGCGCCTCTTTTTGGCTTGGGGAGCTGCAGCGTTCGGTTCATGCATGGGAGATCTCAGACCAGTTGTTACAGATCCGGCAGGATGTGGAGTCATGCTATTTTGCTGCACAGACCATGAAAATGAAGATTCAGACCTCATTTTATGAGCTCCCCACAGACTCTCATGCCTCTTTACGGGACTCATTGCTAACCCATATCCAGAACTTGAAAGACTTGTCACCTGTTATTGTAACGCAGCTGGCTTTAGCAATAGCAGATCTTGCCCTACAGATGCCTTCCTGGAAGGGATGTGTGCAAACACTGGTGGAAAAATACAGCAATGATGTGACTTCTTTGCCTTTTTTGCTGGAGATCCTTACAGTGTTACCTGAAGAAGTACATAGTCGTTCCTTACGAATTGGAGCTAATCGGCGCACAGAAATTATAGAAGATTTGGCCTTCTACTCTAGTACAGTAGTATCTCTATTGCAACAGGATAAGACCTCGTCTAACCTACATGAAGCTGCTTCGGACTGTGTATGCTCAGCTCTCTATGCCATTGAGAATGTGGAGACTAACTTGCCATTAGCCATGCAACTTTTTCAGGGAGTGCTGACATTGGAGACTGCCTATCATATGGCCGTGGCACGTGAAGATTTAGACAAAGTTCTGAATTACTGCCGTATTTTCACTGAACTATGTGAAACTTTTCTTGAAAAAATTGTTTGTACTCCAGGCCAAGGTCTTGGGGACCTTCGAACTCTGGAGCTGCTGCTTATCTGTGCAGGCCATCCTCAATATGAGGTAGTAGAAATTTCATTTAACTTTTGGTACCGACTGGGGGAACATTTGTACAAAACTAACGATGAAGTTATTCATGGCATCTTCAAAGCTTACATTCAGAGGCTGCTTCACGCCTTGGCTCGACACTGCCAGCTGGAACCAGACCATGAGGGGGTTCCTGAGGAGACTGATGACTTTGGGGAGTTTCGCATGAGGGTATCAGACCTGGTAAAGGACTTGATTTTCTTGATAGGGTCTATGGAGTGTTTTGCTCAGTTATATTCTACTCTGAAAGAAGGCAACCCACCCTGGGAGGTGACAGAAGCGGTTCTCTTTATCATGGCTGCTATAGCAAAGAGTGTTGATCCGGAAAACAATCCAACACTTGTGGAAGTCCTAGAAGGAGTTGTCCGCCTCCCGGAGACCGTACATACGGCTGTGCGATACACCAGCATTGAATTGGTTGGAGAGATGAGTGAAGTCGTTGATCGAAATCCTCAGTTCCTTGACCCTGTGTTGGGCTATTTGATGAAAGGCCTGTGTGAAAAGCCCCTGGCTTCTGCTGCAGCCAAAGCCATTCATAACATTTGCTCTGTCTGCCGAGATCACATGGCTCAGCACTTTAATGGACTCCTGGAGATTGCCCGCTCCCTCGATTCCTTCCTGTTGTCTCCAGAAGCTGCTGTGGGCTTGCTAAAAGGGACAGCACTTGTCCTAGCCCGATTACCTTTGGATAAGATTACCGAATGTCTTAGTGAACTATGTTCTGTTCAGGTTATGGCATTGAAAAAGCTGTTGTCTCAAGAGCCCAGCAATGGCATATCCTCAGATCCCACAGTGTTCTTAGATCGCCTTGCAGTGATATTTAGGCATACCAATCCCATTGTGGAAAATGGACAGACTCATCCGTGTCAGAAAGTCATACAGGAAATATGGCCAGTTTTATCCGAGACTCTAAATAAGCACCGAGCTGATAATCGGATTGTAGAGCGTTGTTGCAGGTGCCTGCGCTTTGCTGTTCGCTGTGTAGGCAAAGGATCTGCAGCACTGCTGCAGCCACTAGTCACACAGATGGTGAATGTGTACCACGTACATCAGCATTCCTGCTTCCTGTACCTTGGCAGTATCCTTGTGGATGAATATGGCATGGAAGAAGGCTGTCGGCAGGGACTGCTAGACATGCTCCAGGCACTGTGCATCCCCACCTTTCAGCTCCTAGAACAGCAGAATGGTCTCCAGAATCACCCTGACACTGTAGATGACCTGTTCCGGCTAGCCACCAGGTTTATTCAGCGTAGCCCTGTCACCTTGCTGCGGAGCCAAGTGGTCATCCCTATCTTACAGTGGGCCATTGCCTCTACTACCCTGGACCACCGGGATGCCAATTGTAGTGTCATGAGGTTTCTACGAGACCTCATTCATACAGGGGTAGCCAATGATCATGAAGAAGACTTTGAATTACGGAAAGAACTGATTGGACAGGTGATGAACCAGCTTGGACAGCAGCTTGTCAGCCAGCTGCTGCACACCTGCTGCTTTTGCCTCCCCCCCTATACCCTACCAGATGTGGCTGAAGTGCTCTGGGAGATCATGCAGGTTGACAGACCGACTTTTTGTCGATGGTTAGAAAATTCCTTAAAAGGTTTGCCAAAGGAAACAACCGTGGGAGCCGTCACAGTGACACACAAACAACTTACAGACTTCCACAAGCAAGTCACTAGTGCTGAGGAATGTAAACAAGTTTGCTGGGCCTTGCGAGACTTCACCAGGTTGTTTCGATAGCTCACACTCCTGCACTGTGCCTGTCACCCAGGAATGTCTTTTTTAATTAGAAGACAGGAAGAAAACAAAAACCAGACTGTGTCCCACAATCAGAAACCTCCGTTGTGGCAGAGGGGCCTTCACCGCCACCAGGGTGTCCCGCCAGACAGGGAGAGACTCCAGCCTTCTGAGGCCATCCTGAGGAGTTCCTGTTTGGGGGTGTGAGGGAAAATCAGCGCGGATTTTAAAAAGATGGCTGTGGCCTGCCCGGCGTGGTGGGAGGGGAGCTGGTTTCCTGGTGAACTTTCTAAAAGGAAAAATAATTTTAAGTaaagaaaaaagaaaaaaaaggaagactaaacagaaaccagaaCTGAAACATTCACCTGGTAGCAAATGacacatgcacgcacacacacatacacgcacaAGCGCCAGTGCGCACGTGTACACAGAAAAACAAAAGGACAAGCTTTCTGTGAAACAAAATATTTACTTAGGGATAATGTGGGGATTCACATGAATTAAATAGCTGCAATTGGAAGAAGAGGGTCAGGGTCATTTGTTCAGGTTttctattgttttgtcctctctttcctctcctacccttccttctctttctctctcccctccttttAAATGCAAATGAGTAGAAATTTCTTCTACCTTCCCCAGCTGTTTCTTCCCACCTTTAGAGTTGTTTAGACAAGGAGGAGTAAGCAAGGAACTTGTTCTGCTTTCTATCGTGGTCACATTGGTGATGCTCGGGACCTGCCAGGGTCAGAATTTATGGATATCTGAACCCTGACCCCGTTCATTCTCTCAGTCCACTTCCAATCCACATCAGTTTGTTGTCTGCCTTGGAGAGAAGAGCCAAAACTGGGGTGGGCGGGTGGGTGGGGAGTGCAGGATATAAATGTGTAAGTTTTTGTTTTTTAAGGTTTTTTTCTTAGTGAATTATTCACCCACAGACATGAGAGAAAAAAAGAGGGAGGGTGTGTGGAGAAAAAATGTTTACAGGGCTAACAAGGGATGATGTGTCATTTAGTATGTTACTAAAAAGTGTGGAAATGACTTGATTTTAAGGGGAGGGTGAGGCCGAAGAGGGAAGCCCAAAGCAGATCTTAATGTTTCAAAGGAGTGCAGCCCTTCACAGCCATCAGATATGAGGGCACTGTTCTGTCTGGTGTTGTAGCCATCTCAAGAACAAATCAACAGCAACAAAAGAGAAAGAATAAATTTTTAAAATTTAA

Publications

PMID - Link Title