Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name SLC25A20P1
Wait
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:52246388-52248094  UCSC
Coordinates (T2T) chr6:52085141-52086846  UCSC
Coordinates (hg19) chr6:52111186-52112892  UCSC
Strand +
Parental Sequence NM_000387.6
Parental seq. overlap 1502 bp
Parental seq. overlap (%) 84.1%
Genomic Region Intergenic
Retrocopy Summary SLC25A20P1, located on chr6:52246388-52248094, is a retrocopy of the parental gene SLC25A20. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SLC25A20
Full Name solute carrier family 25 member 20
Also known as CAC|CACT
Coordinate chr3:48856926-48898882
Strand -
Gene summary This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SLC25A20P1
Bonobo Pan paniscus SLC25A20P1
Gorilla Gorilla gorilla SLC25A20P1
Orangutan Pongo abelii SLC25A20P1
Gibbon Nomascus leucogenys SLC25A20P1
Green monkey Chlorocebus sabaeus SLC25A20P1
Crab-eating macaque Macaca fascicularis SLC25A20P1
Rhesus Macaca mulatta SLC25A20P1
Baboon Papio anubis SLC25A20P1
Golden snub-nosed monkey Rhinopithecus roxellana SLC25A20P1
Marmoset Callithrix jacchus SLC25A20P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.050.10.15
log10(TPM+1)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>SLC25A20P1
TGGCACTGCAGCTGGGGCAGCAGAGCCAGGACGGCCCAGGAACTGACAGACTGAGGGATAGGCAGACTGACCATAGCCGACCAGCCAAAGCCCATCAGCCTGCTCAAGAACCTGCTGGCCAGTGGCTTTGGTGGCATGTGCCTGGTGTTCATGGGGCACCCTCTGGACACTGTCAAGGTCCGACTGCAGACACAGCCACCGAGTTTGCCTAGACAGCCTCCCATGTACTCTGGGACCTTTGACTCTCTCCCAAAGACTCTTAGAAGGGACATCACAGGGCTATATAAGGGAATGGCTGCCCCTATCATCGGTGTCACCCCCATCTTTGCTGTGTGCTTCTTTGGGTTTGGTTTGAGGAAGAAACTATGACAGAAACACCCAGAAGATGTGCTCAGCTATCCCCAGCTGTTTGCAGCTGGGATGTTATCTGGTACATTCACCACAGGCATCGCGACCCCTGGAGAACCCATCAAGTCCTTGTTACACTTTCAGCCTTCTTCAGGGGAAACCAAGTACACTGGAACCTTGGACTGTGCAAAGAAGTTGTACCAGGAGTTTCAGATCCGAGGCATCTACAAAGGGACCGTGCTTACCCTTATGTGAGACGTTCCAGCTAGCGGAACGTATTTCATGACAAATGAATGGCTAAAAAATATCTTCACTCCGGAAGGAAAGAGGGTCTGTGAGCTCAGTGTGCCTTGAATCCTGGTGGCTGGGTGCATTGCAGGGATCTTCAACTGGGCAATGGCAGTCCCGCAAGATGTGCTCAAGTATCCCTTCCAGACGCACCTCCTGGGAAATATCCTAACAGTTTTGGAGATGTGCTGAGGGAGCTGATCTGGGATGAAGGAATCACATCCTTGTCTAAAGGGTCTGATGCAGTGATGACCCGAGCCTTCCCAGCCAATGCAGCCTGTTTCCTTGGCCTTGAAGTTGCCATGAAGTTTCTTAATTGGGCCACCCCCAACTTGTGAGGCAGAAGGCTGCTCAAGACTTCTGGATGCTGGAACTGTTGCTGAGAAGGAAGAGTAGTGGGCAGAACTAAGCAGACTTGGAGAATGAGGGGAGGAGACGGTGGGATCAGAGCTCTGCGCATGGACTTGGTGAGACTGTTGCCTTAATGACATCCTCTACCTTGTATAAGTTGGTGTGTCATTTCGCAACTTGAATTCATTCTTGTCAATGTAAGGGACCTTAAGAGGATTTGGAGATCTAGTAGTTTCTAGACCAGATACTACCTGTGGCAAGAATACTGCCTACCAGTTGACGGTTGGCCCTACCACACCCAAAGTGTTTCTCATTAAAGAGGTAATCTCAGCTTCTCACTGGAGGCACTTTGGATGCTTTCAACCAGCTGACCAGGGGCTGAGATCATCTTCAATCCCTAGCCAGGAACACCCACTTGATTTCCAGGGTACCACCTAATCCTGGGCTGCACATGGGGATTTGGACTTGAGCCCCACATCTGTGTCCAACTGGACTGGGCATATATGCTTAGGAAGAGATAACCTATTAGCTATTGATTTTTGCTTTTTTTTTTTTACACAAGTAATCAAAAGTAAAACTAGAGTAGAGTAGCCTAATTTCCCAAGAATGGGTGAAAAACTTTCCTTTCTACACAGTGAGGACAGTCCCAGCCTGCTGGGATAAGTGAGAAAACCCAGGGTGAAGGAAGGCTCTTTCTGCACAATCTTTTCTCATGAGAGC
>NM_000387.6
GAAAGGTCGGCGGCGCCGGCACTGCAGCTGGGGCTGAGAAGCCAGGACGGCCCGAGAactgacagacggagtgacagacggactgacCATGGCCGACCAGCCAAAACCCATCAGCCCGCTCAAGAACCTGCTGGCCGGCGGCTTTGGCGGCGTGTGCCTGGTGTTCGTCGGTCACCCTCTGGACACGGTCAAGGTCCGACTGCAGACACAGCCACCGAGTTTGCCTGGACAACCTCCCATGTACTCTGGGACCTTTGACTGTTTCCGGAAGACTCTTTTTAGAGAGGGCATCACGGGGCTATATCGGGGAATGGCTGCCCCTATCATCGGGGTCACTCCCATGTTTGCCGTGTGCTTCTTTGGGTTTGGTTTGGGGAAGAAACTACAACAGAAACACCCAGAAGATGTGCTCAGCTATCCCCAGCTTTTTGCAGCTGGGATGTTATCTGGCGTATTCACCACAGGAATCATGACTCCTGGAGAACGGATCAAGTGCTTATTACAGATTCAGGCTTCTTCAGGAGAAAGCAAGTACACTGGTACCTTGGACTGTGCAAAGAAGCTGTACCAGGAGTTTGGGATCCGAGGCATCTACAAAGGGACTGTGCTTACCCTTATGCGAGATGTCCCAGCTAGTGGAATGTATTTCATGACATATGAATGGCTGAAAAATATCTTCACTCCGGAGGGAAAGAGGGTCAGTGAGCTCAGTGCCCCTCGGATCTTGGTGGCTGGGGGCATTGCAGGGATCTTCAACTGGGCTGTGGCAATCCCCCCAGATGTGCTCAAGTCTCGATTCCAGACTGCACCTCCTGGGAAATATCCTAATGGTTTCAGAGATGTGCTGAGGGAGCTGATCCGGGATGAAGGAGTCACATCCTTGTACAAAGGGTTCAATGCAGTGATGATCCGAGCCTTCCCAGCCAATGCGGCCTGTTTCCTTGGCTTTGAAGTTGCCATGAAGTTCCTTAATTGGGCCACCCCCAACTTGTGAGGCTGAAGGCTGCTCAAGTTCACTTCTGGATGCTGGAAGCTGTCGTTGAGGAGAAGGAGTAGTAAGCAGAACTAAGCAGTCTTGGAGGGCAAGGGGAGGGGAATGGTGAGATCCGAGCCCTGTGCATGGACTTGGTGAGACTGTTGCCTTAATGACATCCTGCACCGTGTATAACTTAGTGTGTCATTTTGAAACTTGAATTCATTCTTATCAATTTAAGGGATCTTAAAAGGATTTGGAAATGGAACAAGTAGCTTCCAGACCAGATACTACCTGTGGCAAGAATGCTGCCTACCAGTTAACTGCTGGTCCTACCACAGTCAAAGTATTCCTCATTAAAGAGAGAATCTCAGGTTCTCACTGGAGGCACTGTGCATATTTTCAACCAGATCACCAGGAGCTGAGATCTTCTTCAGTCCCTAGCCAGGAATACCCATTTGATTTCCAGGGTGCCATCTAATCCTGGGCTGTACATGTGGATATGGACTTGAGGCCCACCTCTGTGTCCAAGTGGATTGAGCATATATGCCTAGGAGGAGATAGACTGTTAATCGTTGGATTTTGATTTTTTTTTTTTATGCCTGCAAATAATCAAAAGTAAAACTGGAGTAGCCTAATTTTCTGGGAGCAGGTGGAGAACTTTCCCTCCTACACAGTGAGGACAGTCCCAGTCTGCTGGGATAAGTGAGAAAGCCCAGGGTGTAGGAAGGCCCTTTTTACATACTCTTTTCTCATGAGAGCTCACTATTTTAACAATAAACAATAAACGTTGTTTCTAATTTTT

Publications

PMID - Link Title
No publications available for this retrocopy