Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RBBP4P3
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:60872728-60874688  UCSC
Coordinates (T2T) chr6:62040641-62042601  UCSC
Coordinates (hg19) chr6:57840475-57842435  UCSC
Strand -
Parental Sequence NM_005610.3
Parental seq. overlap 1838 bp
Parental seq. overlap (%) 23.3%
Genomic Region Intergenic
Retrocopy Summary RBBP4P3, located on chr6:60872728-60874688, is a retrocopy of the parental gene RBBP4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RBBP4
Full Name RB binding protein 4, chromatin remodeling factor
Also known as NURF55|RBAP48|lin-53
Coordinate chr1:32651208-32686211
Strand +
Gene summary This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RBBP4P3
CCCGCAACACTCGACCCCAGGATTCCCCCAGCTTGCCTGCCTGCCATGGCCGACAAGGAAGCAGCCTTTGACGACACAGTGGAAGAACGAGTGATCAACGAGGAGTACAAAAAATGGAAAAAGAACACCCCTTTTCTTTATGATTTGGTGTTGACCCATGCTGTGGAGTGGCCCAGCCTAACTGCCCAGTGGCTTCCAGATGTAATCAGACCAGAAGGGAAAGATTTCAGCATTCATCAGCTTGTCCTGGGGACATACACATTGGATGAACAAAACCATCTCGTTATAACCAGTGTGCAACTCCCTAATGATGACACTCAGTTTGATGCGTCACACTACAACACTGAGAAAGGAGAATTTGGAGGTTTTTATTCAGTTAGAGGAAAAATTGAAATAGAAATCAAGATCAACCATGAAGGAGAAGTAAACAAGGTCCGTTATATGCCCCAGAACTCTTGTATCATCTCAACTAAGACTCCTTCCAGTGATGTTCTTGTCTTTGACTATACAAAACACCCTTCTAAACAAGATCCTTCTGGAGAGTGTGATCCAGACTTGTGTCTCCGTGGACATCAGAAGGAAGGCTATGGGCTTTCTTGGAACCCAAATCTCTGTGGGCACTTACTTAGTGCTCAGATGACCACACCAGCTGCCTGTGGGACATCAGTGCTGTTCCAAAGGAGGGAAAAGTGGTGGATGTGAAGACCATGTTTACAGGGCATACAGCAGTAGTAGATGTTTCCTGGCATCTGCTCCATGAGTCTCTGTTTGGGTCAGTTGCTGGTGATCAGAAACTTATGATTTGGGGTACTTGTTCACACAGTGCTTCCAAACCAAGCCATTCAGTTGACGCTCACACTGCTGAAGTGACGCTCACACTGCTGCCTCTCTTTCAATCCTTATAGTGAGTTCATTCTTGCCACAGGATCTGCTGACAAGACTGTTGCCTTGCGGGATCTGAGAAATCTGAAACTTAAGTTGCATTCCTTTGAATTACATAAGGATAAAATATTCCAGTTTCAGTGGTCACCTCACAATGAGACTATTTTGGCTTCCAGTGGTACCAATCACAGACTGAATGTCTGGGATTTAAGTAAAATTGGAGAGAAACAATCCCCAGAAGATAAAGAAGACGGGCCACCAGAGTTGTTGTTTATTCATGGTGGTCACACTGCCAAGATACCTGATTTCTCCTGGAATCCCAATGAACCTTGGGTGATTTGTTCTGTACCAGAAGACAATATCATGCAAGTGTGGCAAATGGCAGAGAACATTTACAACGATGAATACCCTGAAGGAAGCGTGGATCCAGAAGGACAAGAGTCCTAGATATGTCTTTACTTCTTGTGATTTTACACTCCCCTTTTTTCTTCTCAACCCTGAGAGTGATTCAACACTGGTTTCAAGACACAGACTTTGTTCAGCTATCCCTCTATATAATAGGTACCACCAATAATGCTATTAGCCCAAACAGTGGGTGTTTTTTAAATATTAATGGTGGGGGGGCTTGATTCAGCAAAGCCACAGACTTACATTGAAATTTTCTTCAGGAATTTTCTAGTAACAACCCAGGTCTAAAGTAGCTACAGAAAAGGGAATATTACGTGTGATTATTTTTCTTCTTATGCTATATCCCCAAGTTTTTCAGACTCATTTAAGTAAAGGCTAGAGTGAGTAAGGAATAGAACGAAATGAGGTAGGTGTCTGAGCCAAGAAGTATAAATACTGAAAGATGTCACTTTTATTCAGGAAATAGGGGAGATTCGAGTCATATAGATGCCTACTCGGAAATCTTGACACCTGACTTTCAGGATGCACATTTTCATACGTAGACCAGTTTCCTCTTGGTTTCTTCAGTTAAGTCACAACTACACGTTCCTCTTTCCCCATATATTTTTGCTCGTTACTGTATTTCTTGAGCTGTTTTCATGTTGTTTCTTTCCTTTCTGTGAAATGg
>NM_005610.3
GGAAACAATAGAGGCCGCGCGCACAGAGCGAGCTCTTGCAGCCTCCCCGCCCCTCCCGCAACGCTCGACCCCAGGATTCCCCCGGCTCGCCTGCCCGCCATGGCCGACAAGGAAGCAGCCTTCGACGACGCAGTGGAAGAACGAGTGATCAACGAGGAATACAAAATATGGAAAAAGAACACCCCTTTTCTTTATGATTTGGTGATGACCCATGCTCTGGAGTGGCCCAGCCTAACTGCCCAGTGGCTTCCAGATGTAACCAGACCAGAAGGGAAAGATTTCAGCATTCATCGACTTGTCCTGGGGACACACACATCGGATGAACAAAACCATCTTGTTATAGCCAGTGTGCAGCTCCCTAATGATGATGCTCAGTTTGATGCGTCACACTACGACAGTGAGAAAGGAGAATTTGGAGGTTTTGGTTCAGTTAGTGGAAAAATTGAAATAGAAATCAAGATCAACCATGAAGGAGAAGTAAACAGGGCCCGTTATATGCCCCAGAACCCTTGTATCATCGCAACAAAGACTCCTTCCAGTGATGTTCTTGTTTTTGACTATACAAAACATCCTTCTAAACCAGATCCTTCTGGAGAGTGCAACCCAGACTTGCGTCTCCGTGGACATCAGAAGGAAGGCTATGGGCTTTCTTGGAACCCAAATCTCAGTGGGCACTTACTTAGTGCTTCAGATGACCATACCATCTGCCTGTGGGACATCAGTGCCGTTCCAAAGGAGGGAAAAGTGGTAGATGCGAAGACCATCTTTACAGGGCATACGGCAGTAGTAGAAGATGTTTCCTGGCATCTACTCCATGAGTCTCTGTTTGGGTCAGTTGCTGATGATCAGAAACTTATGATTTGGGATACTCGTTCAAACAATACTTCCAAACCAAGCCACTCAGTTGATGCTCACACTGCTGAAGTGAACTGCCTTTCTTTCAATCCTTATAGTGAGTTCATTCTTGCCACAGGATCAGCTGACAAGACTGTTGCCTTGTGGGATCTGAGAAATCTGAAACTTAAGTTGCATTCCTTTGAGTCACATAAGGATGAAATATTCCAGGTTCAGTGGTCACCTCACAATGAGACTATTTTAGCTTCCAGTGGTACTGATCGCAGACTGAATGTCTGGGATTTAAGTAAAATTGGAGAGGAACAATCCCCAGAAGATGCAGAAGACGGGCCACCAGAGTTGTTGTTTATTCATGGTGGTCATACTGCCAAGATATCTGATTTCTCCTGGAATCCCAATGAACCTTGGGTGATTTGTTCTGTATCAGAAGACAATATCATGCAAGTGTGGCAAATGGCAGAGAACATTTATAATGATGAAGACCCTGAAGGAAGCGTGGATCCAGAAGGACAAGGGTCCTAGATATGTCTTTACTTGTTGTGATTTTAGACTCCCCTTTTTTCTTCTCAACCCTGAGAGTGATTTAACACTGGTTTTGAGACAGACTTTATTCAGCTATCCCTCTATATAATAGGTACCACCGATAATGCTATTAGCCCAAACCGTGGGTGTTTTCTAAATATTAATAGGGGGGCTTGATTCAACAAAGCCACAGACTTAACGTTGAAATTTTCTTCAGGAATTTTCTAGTAACCCAGGTCTAAAGTAGCTACAGAAAGGGGAATATTATGTGTGATTATTTTTCTTCTTATGCTATATCCCCAAGTTTTTCAGACTCATTTAAGTAAAGGCTAGAGTGAGTAAGGAATAGAGCCAAATGAGGTAGGTGTCTGAGCCATGAAGTATAAATACTGAAAGATGTCACTTTTATTCAGGAAATAGGGGGAGATTCAAGTCATATAGATTCCTACTCGAAAATCTTGACACCTGACTTTCCAGGATGCACATTTTCATACGTAGACCAGTTTCCTCTTGGTTTCTTCAGTTAAGTCAAAACAACACGTTCCTCTTTCCCCATATATTCATATATTTTTGCTCGTTAGTGTATTTCTTGAGCTGTTTTCATGTTGTTTATTTCCTGTCTGTGAAATGGTGtttttttttttgttgttggtttttttttttttttttttAACTTGGGACCACCAAGTTGTAAAGATGTATGTTTTTACCTGACAGTTATACCACAGGTAGACTGTCAAGTTGAGAAGAGTGAATCAATAACTTGTATTTGTTTTAAAAATTAAATTAATCCTTGATAAGAGTTGCTTTTTTTTTTTAGGAGTTAGTCCTTGACCACTAGTTTGATGCCATCTCCATTTTGGGTGACCTGTTTCACCAGCAGGCCTGTTACTCTCCATGACTAACTGTGTAAGTGCTTAAAATGGAATAAATTGCTTTTCTACATAACCCCATGCTGATGGGTTTTATTTAGTATAAAACATCCATCAAACACCAGTCTCTGGCTTCTAGAAGAGTCCTTCAGATGACAGTTGTTGTCCATGGTCTTTGACTATCAAGAGCAGAATTAAATGTAATAGTCCCAGAGCTGTAGAAAAGAACTTTACTCCTTCCCAGGGAAAGTGAAAGACATAAAACACTGAATCAGAGGTGGCACAGATTAGTCTTTGATAAGGTAACGTTTCTTTGAAGTCTATCTGTAGAGAACTACATGGACTTCCAAGAGTGTCAAAGGCAGTGTGGTAGAGAGAATTTAAGGCAAGATTTAAATTTGGAAAAGGTGCTTGAACCTTTTCTCAGAGGTTTTATTTCCCCAGTATGTTTTTCACTGGGGCCTTTACTTAGGTTAGAAATAATAGGCTTTGAAGGCCTCTATCACCAGATGCAATAACCAGATAAAATTCCTGTTTTTTCCCAATCGCTTAGTTTTTTGTTGTTGTTGTTTTTTAACTGAGTAGATCATTCTGACCCAGAACTACTTTCATGAGGTAAGATCTTTGGGAAAATCTGAATAGCGTTAACCATTAGATTCAAATCTCAAATGGTTTCTTTTCAAGTCTAGTTGTTTTAGAGTATAGTGAGAAATACCTTGACACAATTTTAAGAGTAAACTATATGGGTCAGCATATCCTTGAACAAAAAGTAGACTTTGTAAAAGTATTCATTTAAATTCTAACACTCGTGGCACAAAAGAATGGAAATTGTAAACCCATGTAATGGAAATTGGCTATCTTTTTGACCCCACATGTGCCCCTCAAAAATGTTTTTGGTTTGGGTCAACACAAGGCAAGATACATTCTTTAAAATACTCCCAGATGTGTCCATACATTCATCCTTCACTCAGTGCATATGTGAGGGTTGTTGCTGGAAGACAGGAGGCTCATCTTTCCTTTCCTTGGTGCATTGAGATCAGTATCAACAGCAGATGAAATAGAATCCAGCAAAGAGTTGACATGTTCTGCCTCCGGCCAACTCTAGAATCTTTTTAAGCAGGTCAGCCAGTATTTGCAACTTCCACAGGATGAATTGCTTGCCAAGTTTCTGGCACTCTTGTCTGGTTGGAAGAGTACATCCAAAGGGTACTTAGTGATCCTTTGCTAAGAAGTTTTTTGCTGTTTCCGGGTTACAGATTTGGCCATATATTTCTAAACAGCCCCTGTAAAGTTGAAAGAAAAAGTTTATAACAGTGAACTTCTGAGGTTTAGTTACTGCAGGCTTTGTTGAGAAGAGATTGTTACAGTGTGATTTATGGATGATCAGGGATGACTTTCCCCTAGCAAATATTTGGATGCCTCCTGTTTGTCAAATAGAATGAATGGTGATGGTGATGGGAGGGATAGTTAAACGTTTTCTCTGCTAGGTTAACTTCTTACAGGTATAATTACAATGCCTGAAATTCTGTAGTTTCATTTCTTTGGATTAGTCGTTGTCTTTTCCAGATTGTACACAATCTGATCAACACAAAGGTAGTTAGTAGATCATTAACCTCAATTGCAAGGTTATAATTTCTCAAACATTAAGCATATTATCAGTCATGTGGATTCAAACACAGTATAAGAAAATCCTCAAGgctgggtgtgatggcttatgcctgtaatcccagctacttagcaggctgaggcaggagtattgtttgaacccaggaggcagagttgcagtgagccaagatcgtgccactactccagcctgggcaaaatagcaagacccgaccccccatctctactaaaaagaaatttaaaaaaataaaaTCCTAGAAAATTAGAAAAAGCAACAATAGTTACTTGTGggccaggcgcggtggttcacgcctgtaatcccagcactttgagaggctgaggcacgtggatcacaaggtcaggagttcaagaccagcctggccaagatggtgaaaccccgtttctactaaaaatacaaaaactagctggccgtggtggcatgctcctgtagtcccagctactcaggaggctgaggcaggaaaatcacttgaacccaggaggtggaggttgcagtgaactgagaccgtgccactgcactccagcctgggtggcagagcgagactgtctcaaaaaaaaaagaaaGTTGTGAATTTGATGTAAGCTTAGGAAATGAATAAAATTTATAGGCATCTGTATAATGTACAACTTGACACGGACTTTCTTTTATCCTTAGTTTCTTTCACGGACTCTAGAACTTTTATCAGAATATACTGGTAAAACATTGGGGGAGGGATCCTGAGTAGGTGATTGGTCAGAAAGATGCCTTCAGTTTTGTCAGTGTCTAAAAGTTAAGTCTGTTTAggccaagcatggtggctcacacctgaaatcccagcactctgggaggccgaggcaagtggatcacaaggtcaggagatgagaccatcttagccaacatggtgaaaccccgtctctactaaaatacaaaaaaattagccaggcgtggtggtgcgtgcctataatcccagctacttgggaggctgaggcaggggaatcgcttgaacccgggaggcagaggtcacgccactgcactccagcctggcaacagagcaagactccgtctcaaaaaaaaaaaaaaaaaaaaaGAGTAAGTCTGTGTAACATGAACATCTCTGCTTCCACCCAAAACCACAGCCTTTGAATATTATATAAGGAACTTAATGGATAGATATGTTTATTATTTTTGATAGCACAACTGCTTTCTCTGCTATTATAAGGAAAACTGAGAATAGCAGGTGGGTAGGGTAGGATGAGGAAACAAGATGCCCAAAGCCTAGATGCCACAGAATTCATGGTGATAATCAGGGCATATTTTGAGTCCTACTAGAAACAAACATTCCAAATGAACTCTGAATGCCTGACTCAGGCGTTTTGGAGGTTTGGGTTATCCCCTTGTCATTAGGCACACAAGGGTTTTTTGttgtttttgttttttgggtttttgttttgttttgaggcagtctcactctgttgtacaagctggagtgctgtattgtgatcttgactcactgcaacctctgcctcctggttcaagcgattctcctgccttggcctcctgagtagctgggattataagtgcctgccactatgcccggctaatttttgtatttttagtggagatggagttttgccatgttggccaggctggtcttgaactcctgactccaggtgatccaccctcctcagcctcccaaagtgctaggattacaggcgtgagccaccccgtccggccTGTTTTTAAGGCATTAATTAGTATTGTTAGGAAAGCAGTAACAATGCAAACACCACTCTTCTCTTCACAAAGATCACCTTGAGACTGTGTCTCCATTCCACCTGCCTGAGAAGTGGGAGCATCAGCCTGTTCCAGGCTCTTGGGTAGTAGCATAGCCCTTTAAAAAGAGAGAGCCATTTTCCATGTGTTTTTGGATAAGCACAATTTGAAAATCATTTCCCAAATCCTCTTTTTGTTTTTGATTCTAAGGTAAAATTTTCCCTAAGCCCTCCCACCATCCCCTCAGCCAGTATTAGATGAGATTTGTATAGCAGCAGAAACTGACTTATAAGTAGAGAGCTCTTCAGCAAGACTGAGCCTTAGCTGTTCCATCTCTTTGTTCTTCTGTTGCTGGAGTTGCACCCCATTTCTTAACTGCCTCTGGCGTTCTTCCATTTCCTCCAGCTGTTCCTGCATGAGATGGCCAAGAACATTTCTAATGAGCCAAACAATAAAAACTCACATTGTCCACTCTTACTTATAAAACACTTTTTTGTTCATTGTTTAATCTTGATAGCAGTATTGAGGCTGGTATTTATATGATAGGTTATGAAACAGGTTCAAAGAAGTTGTGTCTTGGAAAAAAAGTGACAATGCTTTTGAAAATGATGACGAAAAAGGCATCTTGTCTGTTAACCACAGCTTGCTTTAATAGAATCCTGGGAGGGTGATTGGGACTTTTTAGTATTACAACCTTAGTGTCATTGAGGAGGATTTTGGTCTAGTTAGTGGGCTGAGTTTCATATACCTCTCCCTCCATGTGCAGGTTTGTTAAGATAATTGGTAGTTTTTAATAATATAAAATACTTAAGTTGAAATACAAAAGTGTGGCAACAATTATTAAATATTGGCTAGAATTCTAGGAGAGTTACACAACTAGTGGAAGTCCATGTTTAGAAAATAAATGGCTTGTTTAAGGAAAAGTTTTTGTGTCCAAAGCTCCTTAAAGTCAGAGAGATTTCTACCTGGTACTTAACATCATATGGAAATTGATGCTTTAGTGAGGGTGTTGGCTATCCTATTGCTAATTTCCTGCATCCTTTTTTCttctttatttttgtatagagacagggtctcgctatgttgcccaggctggtcttgttcctgggctcaagcagtcctcccgcctcggtctcccaaagtgctgggattacaggtgtgagccactgtgcccagcTTATCCTTTTTTCATTACACAAAAAGACTGAATTTGGTTAGTTCTAAGTTGGAAGATAAAGATGGTATGCACAGGAGGCCCTTGGGAGCCCTCAGATAACTTTCTCATTCTTCCAGAATCAGGCTGGGATGCATTCTGTAAATTTTCCCTGCCTAGGATGTATACCTGAGGAATAAGGTAAGGAAGATGTCAGCAAGTCAGTCTCTGGTTTACCTGCTAGCTGGCATGGATCCTTAAGGAAGCAGGAGGGAGTTGGGAAGAGAGGAAGGGGTGAAGTTGGTATCTTTTAAAGCGAGAGTGATTTTACCTCAGATTTTGAAGAATACTAAGGAATCCAGTTGTTGGGGTACATGCTATTATTAGAAGGATCTAGATAATTTGTCCTCTGAGTCATACTTGACATTGTACCTGTGGCACATCAATCCGCACTGTTTGATACTCTGGCTGAATCTCAGCTTTCACCAACATTGTCAAAGGACCTTTTTTAGTGCCCAGCCATGCCTAAGAGTGTGTCATCTGAAGAGGGAAGCATCTGCATACTGCTGTCCTGATTGCTCAGTCCTCACTACCTACCAGACCCGTTGGTAAGGTACAAAAGTACATGCTTGGAAAAGCAGTCTGCACCACCAGTGATAAGCTGTGACAGAGTGGAACAGCCTCAATGAAATGAAGGAAGGATTGCTACAGTGGCATTAAGGATGGTCTCTTAATCCTGTGTTAACCACTAGATTAACTTTACAATCAACTCAAAATCCTTCAAAGGCTTTCCACTTTCTTTAGTGGCATTCAGACCCCCTCTAGTTTGACCCCTACCTCCAACTTGAACCTCTGTTACTCTTCCGTATGAACATTTTCCTCTAGCCCTGGACTActagtaccgaagtcactagtcacataggactcatttgaaatatgactagtctcaattgagatgtaatgtaagtgtaaaatacacagcagatttctaagacagcacacaaaatgtaaaatatgtcaaaaatatttgatactgattacatgttgaaatatatgtgttgggttaaataaaatgcattaaagttaa

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