Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name LRRC59P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:63440641-63443913  UCSC
Coordinates (T2T) chr6:64586580-64589852  UCSC
Coordinates (hg19) chr6:64150546-64153818  UCSC
Strand +
Parental Sequence NM_018509.4
Parental seq. overlap 1179 bp
Parental seq. overlap (%) 40.6%
Genomic Region Intragenic (LGSN)
Retrocopy Summary LRRC59P1, located on chr6:63440641-63443913, is a retrocopy of the parental gene LRRC59. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name LRRC59
Full Name leucine rich repeat containing 59
Also known as PRO1855|p34
Coordinate chr17:50381238-50397523
Strand -
Gene summary Enables RNA binding activity and cadherin binding activity. Predicted to be involved in positive regulation of Ras protein signal transduction and signal transduction. Located in endoplasmic reticulum and mitochondrial nucleoid. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LRRC59P1
Bonobo Pan paniscus LRRC59P1
Gorilla Gorilla gorilla LRRC59P1
Orangutan Pongo abelii LRRC59P2
Gibbon Nomascus leucogenys LRRC59P2
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>LRRC59P1
AGGCGACAGAGGGCTCAGGTGTGGTGGGTTGGGTGGGGGCCCGCTGAACTGACCAGCGGCATTTCAGCTCATTTACCCCCACCCATCAAAACCCTGGAGCCAGGTCCGTTCAGCCGACCGTCACCATGACCAACGCAGATAGCGAGGGCGGAAACCTCCGCCACCAGCTGGACAGCAACAAACAGGACCTGAGCCTCAGCAACCTGGATGAAGACCCGGTCAAGGAGCTGGCTGCCCTTCCAAAGACTACCACACTGGATCTGTCTTGTAATAAATGACTATTGTTAATGACTATTCTCCCGTCGGATTTCTGTGGCCTCACACACCTGGCGAAGCTAGACCTTAGAAAGAACAAGCCGCAGCACCCACCAGCAGACTTGGGCCGTTTGGTCAACCTCCAGCACCTGGCTCTCCTCAACAACAGGCTGGTCACCTTGTCGTCAGCTTTGCTCAGCTGAAGAACCTGAAGTGGCTGGACCTGAAGAATAACCTCTGGATCCCGGCCTGGCCAAGGTGGCAGGTGATTGCTTGGGTGAGAAGCCATGGAAACAGCATGCAAACAAGGCATCACAACACATGAAGGCTGTACAGACAGACCACAAGTGGGAGAGGCAGCAGGGTTGGAAGTAGAACGAGAGGCAGAGAAGTATGAGGCAAAGCAGCGAGCTAAGGAAGCTCAGGAGAGGAAATGCGGAAGCGGGAGAAGGCAGAGGAGAAAGAGTGCCAGAGAAAGGAGTATGATGCCCTCAAAGCAGCCAAGCGGGAGCAGATCATACCTACCAAGGAAACAAATTAGGCCCCCAAATCTAAGTCCGAATCCTGCCCCTGCAAGCCACTCCCCCGGAAGCACACTCGTTTCTGGTTGTGCAGCGGGGGCGCTGGTTGCTTGTCAGGTGACACAGCTACAGCAGCTGCCCCTTcCTTTGCACCAGCGTGAACACCATCTGTGACAATGTGGTCCAGGGTCTGCACCACCATGAGATCCTCCAGACCGACTCTCAGCAGTGAGCTTGTCCCCAGCACCTGCTGCCTCCCAGCCTTGGAGCTTGGATTCCTATGGAATTGGGCTCTGCTGGACACAAACTCTTTTTAGCATCAGACCTACCTGCCATCATCAAATGGCTGCTGATTGGTACTTGAGACCTCCTCTTTGTAGGACTTCTTCATTCCTTAGTCAGGGTTTCCTGGTGGAATGAGGAGAAATGGGAGGTGGTGGGGGACAGTTACCTGCATGCCTAAAGGAATAGGCTTGGGGGTGGGGAGAAAGAAAACATAGCCATTTCTAGTTGTTACACAAAGCTGTGTAAAGGCTCATTTCTACTAAATGGTCAGCTGTCAC
>NM_018509.4
ACGGAAGTGGTCGTCGTCGCGGCACCGGTGGGAGCTAGGCGCGAGGCTCGGAGTGCGGCCAGCGGGCGGAGGCGGTCTCGCATCGGCGGCGACGGAGGGCTCAGGCGTCGTCGTTTGGGTGGGGGGCCGCTGAACTGACAAGCGACATTTCAGCTCCTTTCACCCGCCGGAACCCCGGAGCCGGGGCCCGCTCAGCCGGCGTTACCATGACCAAGGCCGGTAGCAAGGGCGGGAACCTCCGCGACAAGCTGGACGGCAACGAACTGGACCTGAGCCTCAGCGACCTGAATGAGGTCCCGGTGAAGGAGCTGGCTGCCCTTCCAAAGGCCACCATCCTGGATCTGTCTTGTAATAAACTGACTACTCTACCGTCGGATTTCTGTGGCCTCACACACCTGGTGAAGCTAGACCTGAGTAAGAACAAGCTGCAGCAGCTGCCAGCAGACTTTGGCCGTCTGGTCAACCTCCAGCACCTGGATCTCCTCAACAACAAGCTGGTCACCTTGCCTGTCAGCTTTGCTCAGCTCAAGAACCTGAAGTGGTTGGACCTGAAGGATAACCCCCTGGATCCTGTCCTGGCCAAGGTGGCAGGTGACTGCTTGGATGAGAAGCAGTGTAAGCAGTGTGCAAACAAGGTGTTACAGCACATGAAGGCCGTGCAGGCAGATCAGGAGCGGGAGAGGCAGCGGCGGCTGGAAGTAGAACGTGAGGCAGAGAAGAAGCGTGAGGCTAAGCAGCGAGCTAAGGAAGCTCAGGAGCGGGAACTGCGGAAGCGGGAGAAGGCGGAAGAGAAGGAGCGCCGGAGAAAGGAGTATGATGCCCTCAAAGCAGCCAAGCGGGAGCAGGAGAAGAAACCTAAGAAGGAAGCAAATCAGGCCCCGAAATCTAAGTCTGGCTCCCGTCCCCGCAAGCCACCACCCCGGAAGCACACTCGTTCCTGGgctgtgctgaagctgctgctgctgctgctgctATTTGGTGTGGCGGGAGGGCTGGTTGCTTGTCGGGTGACAGAGCTGCAGCAGCAGCCCCTCTGCACCAGCGTGAACACCATCTATGACAATGCGGTCCAGGGTCTACGCCGCCATGAGATCCTCCAGTGGGTCCTCCAGACCGACTCTCAGCAGTGAGCTTGTCCCCAGCACCTGCTGCCTCCCAGCCTTGGAGTTTGGATTCCTATGGAATTGGGTTCTGCTGGACACAACCTCTTTTTAGCATCAGACCTACCTGCCATCATCAAATGGCTGCAGATTGGTACATGAGACCTCCTCTTTGTAGGACTTCTTCATTCCTTAGTCAGGGTTCCCTGAAGGAATGAGGAGAAATGGGAGGTGGCGGGGGGGCGTGGGGGGCAGTTACCTGCATGCCTAAAGGAGTAGGCTTGGGGGTGGGGAGAGAGAAAACATAGCCTTTTCTAGTTGTTATATAAAGCTGTGTAAAGGCAAGGCTCGTTTCTACTAAATGGTCAGCTGTCACTACATTTATACTTTTGTATGCCACAAACCCTTTCATTCCTCCCTGGGAATCAGGGTAGATCAGGAGGAACTGGGGGGGACTAGAACACCACGCTCAGTAAATCCAGTCTAAACTGGGAGGTAGGGGTATTCCTGTTTTCTTTAGGACCTCAGAGATGTAAGCATTTTAGCAGCCAcacaaaatctctggctatgaaagggacttcatgaccatccagtccaatataacacttgcagacagagaaactgaggtcttccatgacttgcctagtctcccagctagtttgaggcaaaactggattcccactctggtattctttcttccCTTTACATCATTTTCCCTCCTTTATAATGTCCTGAGAGACCAGAACTCACACCAGAATCGATTATTCCTCAGGTGAAGCATAGACTCTTTCATGGTAGACAGATTTCACGACTCAGAGATAGAAATCTCTTGCTATCATCAGGTCACGGGCAGCTCCTGTGGAGTCCTGCCCAACTTATGTGGCTTCCATAAAATGGCAACAGTCCAGGCTCCTTGCCTAATTTTAGAGCATTAACTCCCTAATTGCCAGTAAGCAAGGAGGTGGATCTCTGCAAACCTACACTGTCTATGACAGCTCTAGTTGTACTTGGTGTGACTAAATACCTCAAAGGCAACCTGCTTCTGCAGGTTTTGAAGTGTCAGCTTCATAAGACACTGAGGTTTAGAATTGTTTGATTCTAGACCATAACTGAAGGGCATAAATGGAAACAGGATATGAAGGGAAACAAGTAGCATCATGGAGCTGAAAAGTGGTGCATCACCCAATGGCTAGCACAAACAAGGATCACACTGTCCATTCTCTTGTCTGCTAAATTAAGCATTTTCTTGCCTCCTTTGCTTCATCTTTTCACAACAGCTGGATAGAGGGATCAGAAATGACTGTGTCATGGTGCTCATTCACTGCAAACTCCCAGTTGCAAGCTCCTTGGCTCCCCCGGAGGGAGCAAGAATCTCATAGTTCAGAGACACAGAGGGCCTTTTAGCCCTAATGACCTTTTGGATGGGACTGCAACTCATGACTATCCTGATATTGGAAGAAAGGACTTTGTTAATCTTCTCCCCCATAGCTCTGCTGCGTAGGTCTACATCTTACTCAGAATCACTACACATTCCTTTAGTCTTCCTCCAAGCTCCAGAGCCATTGGTACAAATGCTTTATTGAAACTAAATACATAATACACACAATGAGATGAAGACAATATAGAAGTCCGCATAGTCATCATAATCCCGTTCCTTGGCCGGTTGAGGCAGCTCAGTGGCTGAGCCCAGTCAAGCCAACCCGCAGCTTCACTCACGACTTCAAGATTTGATGCTAATTCTTTTGGATTTCTACAGTTATTAAATAAGTGTCTGAGTGGA

Publications

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