Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SNAPC5P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:6346413-6347391  UCSC
Coordinates (T2T) chr6:6215325-6216303  UCSC
Coordinates (hg19) chr6:6346646-6347624  UCSC
Strand -
Parental Sequence NM_001329615.2
Parental seq. overlap 847 bp
Parental seq. overlap (%) 64.3%
Genomic Region Intergenic
Retrocopy Summary SNAPC5P1, located on chr6:6346413-6347391, is a retrocopy of the parental gene SNAPC5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SNAPC5
Full Name small nuclear RNA activating complex polypeptide 5
Also known as SNAP19
Coordinate chr15:66489748-66497762
Strand -
Gene summary This gene encodes a subunit of the small nuclear RNA (snRNA)-activating protein complex that plays a role in the transcription of snRNA genes. This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription. The encoded protein may play a role in stabilizing this complex. A pseudogene of this gene has been identified on chromosome 6. [provided by RefSeq, Jul 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SNAPC5P1
Bonobo Pan paniscus SNAPC5P1
Gorilla Gorilla gorilla SNAPC5P1
Orangutan Pongo abelii SNAPC5P1
Gibbon Nomascus leucogenys SNAPC5P1
Green monkey Chlorocebus sabaeus SNAPC5P1
Crab-eating macaque Macaca fascicularis SNAPC5P1
Rhesus Macaca mulatta SNAPC5P1
Baboon Papio anubis SNAPC5P1
Golden snub-nosed monkey Rhinopithecus roxellana SNAPC5P1
Marmoset Callithrix jacchus SNAPC5P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SNAPC5P1
ACCAGGAAACATGCCGAGCTGGGTCAGGAACTGCGCAAGGAGGAGGAGACACTGCTCCTGTTGAAGGCAGCCCTCGCATGACCTGCTGAATCACATCAAGGTTGAAGCATTGGCCCTCCAATCAATGATTAGTTCTGGGAGAGGGGATGAGGTGCTGTCTTCTCCAACTTCTCCAACTGTGCCTGAACAGTCACACGTCATGTCAGTGCATATAGAGAATGAAGCATCAGTCAACCAAACTACGCTGGAGTGGAGCATAGAGTCCTGTGACAGAAGAGGAGGAGGAAGAGAAAGAAGAATCAGATCCCTAAAGGAGGGAAAAAGCCAGGATTCATTATACAAATTAAATTTCTAAGTCTCAGGCTCTTTCTCCCCAAGGAAATCATCTTGCCATGAGCCCTAGGGCCTGCTTGAATGGAGAGCAAGAACTATAGGAGGATGTGTAGCTGCAAAAATTTCTCATCAATAACTCAATCTTCAGAACGTTATGACATACAGAAAATCAAAGATGCTGTGTCTTAGCATTGAGCAATATGGGTGGTGCTATGTCTGTAGTCTGGTCAAATTCAGTAACTGTGTTCAAAACAAAATTTCCTCTGGAATACTATTGAGAAAATCTGGCATTTGCAAAAAGGGCAGAGTTTAAATATGAGCCAGTCTTTCCAATCAACAATACCTCTTTTAAGAAAACCAACTAACAGCTGTTTGCATGCCGTTGAATCCTTGTGAGCAGTTAGGCCACAGTCTAGGACAGAAAGATGACACGGGGAAGGACTGAGGGCCATCTGAGAACAAAAGTTGTTGCTACTTCTCAGAGGCATTGAGACACACTGCATGCTGTAGACTGCTTTGTGTAACTGTTGTCACATCTTGCTTGAGATGTCATTGGCAGAATGTTCTTAAAAATAAATTATAGATAAATAGCCATCATGGAGTTTGCTGGTTTCTAGATAGCAAAAGAGAAAAGAAGCAGTTCCTg
>NM_001329615.2
AGCCCGGAGGTTGGCTATGTGACCAGGCAACATGCTGAGCCGGCTTCAGGAACTGCGCAAGGAGGAGGAGACGCTGCTGCGGTTGAAGGCAGCCCTGCACGACCAGCTGAACCGCCTCAAGGTTGAAGAATTAGCCCTCCAATCAATGATCAGTTCTAGAAGAGGGGATGAGATGCTGTCTTCTCACACTGTACCTGAACAGTCACATGATATGTTGGTGCATGTAGACAATGAAGCATCAATCAACCAAACAACCCTGGAGCTGAGCACAAAGAGTCATGTGACggaagaggaggaggaggaagaggaagaagaATCAGATTCCTAAAGGAGGGGGAAAGCCAGGCTGGTCAGTTATACAAATTGCATTTCTAAGGCTCAGGCTACTTCTCCTCAAGGAAATCATCTTGCCCTGGGCCCTGTGATCTGCTTGAAAGGAAAGCAAGAACTATAAGGAGGATGTGTAGTTGCAAAAATGGCTCCATCGGTAACTCAAGCTTCAGAATGTTATGACATACAGAAAATCAAAGATGCTGTGTCTTAGCATTGAGTAATATGGGTGGTGCTGTCTGTAATCTGGTCAGATTCAGTTAACTGTTCAGAACAAAATTTCCTCTGAAATACTGTTGAGAAAGTCTGTCATTTGCAAAAAGAGCAGAGTTTAAATACAAGCCAGTCTTTCCAGTCAACAATGCCTCTTTGAAGAAAACCAATTAAAGACTGTTTGCATGCCGCTGAACCCTTGTGAGCAGTTAGGACACAGTCTAGGACAGAAAGATGACAAGGGGAAGGACTGAGGGCCGTCTGAGAGCACAAGCTGTTTCTACCTCTCAGAGGCATTGAAATATTGCATGCTATAAACTGCTTTGTGTATCTGTTACCACCTCTCACTTGAGACATCACTCACTGGTAAAATGTTTTATAAATAAATTTATAAGTAGCCATCATGGAGCCTGCTGGTTTCTAGATAGCGACAGAGAGAAGCAGCAGTTCCTTCTCTGAGGAAAAGATACAACAGGATGGTTTGAAATCCATTTCTGGTCCTTAAGAGAGATGTGCCATGCTTGGAAGACTGGAttttttgttttgttttttgttttgttttgtttgagacggagtttcactcttattgcccaggctggagtgcaatggcgcgattttggctcactgcaacctccccttctcgggttcaagtgattcttctgcctcagcctccagagtagctaggattacaggcatgcaccaccacacccggctaattttgtatttttagtaaagatgggatttttccatgtt

Publications

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