Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TMEM98P1
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Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:64733306-64733828  UCSC
Coordinates (T2T) chr6:65886887-65887409  UCSC
Coordinates (hg19) chr6:65443199-65443721  UCSC
Strand -
Parental Sequence NM_001301746.2
Parental seq. overlap 449 bp
Parental seq. overlap (%) 10.5%
Genomic Region Intragenic (EYS)
Retrocopy Summary TMEM98P1, located on chr6:64733306-64733828, is a retrocopy of the parental gene TMEM98. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TMEM98
Full Name transmembrane protein 98
Also known as TADA1
Coordinate chr17:32928153-32944315
Strand +
Gene summary This gene encodes a transmembrane protein. A missense mutation in this gene result in Nanophthalmos 4 (NNO4). Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TMEM98P1
Gorilla Gorilla gorilla TMEM98P1
Orangutan Pongo abelii TMEM98P1
Gibbon Nomascus leucogenys TMEM98P2
Green monkey Chlorocebus sabaeus TMEM98P1
Crab-eating macaque Macaca fascicularis TMEM98P1
Rhesus Macaca mulatta TMEM98P1
Baboon Papio anubis TMEM98P1
Golden snub-nosed monkey Rhinopithecus roxellana TMEM98P1
Marmoset Callithrix jacchus TMEM98P1
Bonobo Pan paniscus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Related Sequence

>TMEM98P1
GTGATTGTTGCCATAAGCGTGCTGGCTACCATCTTTCTGGCTTTGTTTGCAGTCTTGGTGGTGGTTTGAGTGCAGCGCTACTGCTGGCCAGGAGACCTGCTGCAGCGCTATGATTCTAAGCCCATTATGAGTCTCTTGGGTGCCATGGAGACCCAATCTGAGCTCTCTGAGTTAGAACTAGATGATGTCATCATCGCCCACTCTGGCATAGAGCCCATTCTGGAGAATGAAGACTGGATCTAGGATGCCTTGGGTCTCATGTCCCACTGCATTGTCATCTTGAAGATTTGTCACACTTTGAGAGAAAAACTTGTTGCCATGACAATGGGCTCAGAGGCTGAAAAGAAGACTTCAACCACTGTCAGCAGCATCATTGTGGTGGCCAAGTGGATCATCCCCAGAGTAGATGATGTTGTGAAATCAGTGTACCATCTGTTAAGCACCAAGCTCCTGGATGTGAGTATGACTGCCCTGCTCCTGTCAGTCATCAGGTGCTGGTAACCAGAAATGCCTGCCATCTGAA
>NM_001301746.2
ATGCTCCGCTGCAGGCCCGCGCCCGCGCCCGGACTTTGCCATCGGCGGGGCAGTCGCGGGATGCGCCCGGGAGCCACAGCCTGAGGGTTTAAAAAGCTATTTTAAggccgggctcggtgtctcacgcgtgtaatcccagcactttgggaggcccgagGCCCTCAGGTCTCTGCAGGTGTCGTGGAGGAACCTAGCACCTGCCATCCTCTTCCCCAATTTGCCACTTCCAGCAGCTTTAGCCCATGAGGAGGATGTGACCGGGACTGAGTCAGGAGCCCTCTGGAAGCATGGAGACTGTGGTGATTGTTGCCATAGGTGTGCTGGCCACCATCTTTCTGGCTTCGTTTGCAGCCTTGGTGCTGGTTTGCAGGCAGCGCTACTGCCGGCCGCGAGACCTGCTGCAGCGCTATGATTCTAAGCCCATTGTGGACCTCATTGGTGCCATGGAGACCCAGTCTGAGCCCTCTGAGTTAGAACTGGACGATGTCGTTATCACCAACCCCCACATTGAGGCCATTCTGGAGAATGAAGACTGGATCGAAGATGCCTCGGGTCTCATGTCCCACTGCATTGCCATCTTGAAGATTTGTCACACTCTGACAGAGAAGCTTGTTGCCATGACAATGGGCTCTGGGGCCAAGATGAAGACTTCAGCCAGTGTCAGCGACATCATTGTGGTGGCCAAGCGGATCAGCCCCAGGGTGGATGATGTTGTGAAGTCGATGTACCCTCCGTTGGACCCCAAACTCCTGGACGCACGGACGACTGCCCTGCTCCTGTCTGTCAGTCACCTGGTGCTGGTGACAAGGAATGCCTGCCATCTGACGGGAGGCCTGGACTGGATTGACCAGTCTCTGTCGGCTGCTGAGGAGCATTTGGAAGTCCTTCGAGAAGCAGCCCTAGCTTCTGAGCCAGATAAAGGCCTCCCAGGCCCTGAAGGCTTCCTGCAGGAGCAGTCTGCAATTTAGTGCCTACAGGCCAGCAGCTAGCCATGAAGGCCCCTGCCGCCATCCCTGGATGGCTCAGCTTAGCCTTCTACTTTTTCCTATAGAGTTAGTTGTTCTCCACGGCTGGAGAGTTCAGCTGTGTGTGCATAGTAAAGCAGGAGATCCCCGTCAGTTTATGCCTCTTTTGCAGTTGCAAACTGTGGCTGGTGAGTGGCAGTCTAATACTACAGTTAGGGGAGATGCCATTCACTCTCTGCAAGAGGAGTATTGAAAACTGGTGGACTGTCAgctttatttagctcacctagtgttttcaagaaaattgagccaccgtctaagaaatcaagaggtttcacattaaaattagaatttctggcctctctcgatcggtcagaatgtgtggcaattctgatctgcattttcagaagaggacaatcaattgaaactaagtaggggtttcttcttttggcaagacttgtactctctcacctggcctgtttcatttatttgtattatctgcctggtccctgaggcgtctgggtctCTCCTCTCCCTTGCAGGTTTGGGTTTGAAGCTGAGGAACTACAAAGTTGATGATTTCTTTTTTATCTTTATGCCTGCAATTTTACCTAGCTACCACTAGGTGGATAGTAAATTTATACTTATGTTTCCCTCAAGTGTGTAGTTATTGAGTCAAATTCATATGCATGGTGTATTGTGGGACATACTTAGATGGAAGGAGAGAGCCTAAGAATCCTGAGGATGATTTCTGTGTATGCCTCAAAATGAGATATTTAggctgggcgcggtggctcacacctgtaatcctcgcactttgggaggctaaggtgggtggattgcttgagcccaggagtttgagaccagcctgggcaacatggtgaaacctcatctctacacaaactacaaaaattagctgggcatggtgacacgtgcggctgcttggtaggctgaggtgggaggatcgcttgagcccaggaggtgaaggttgcagtgagccctgattgtgccactgcattccagcctgggcgacagagtgagaccatgtctccaaaaCATACATATATATAAAATATATTTAAAGACCTCTTGGAGTTCAGGCAGAAGTGAAGATAGCACTATGAAGTAGTTTCCACATTAACAATAGCAATGACTTGAACGATGTGTTCCCCCTTTCTTCTGATATTAATATCTGTTCATTTTGCAAACATTGAAAGATTATGAAAGCTATGACCCAGAATCACAATTATATAATTTGGATACATACCCAAATGGCATAATTTCTGTCATAAGCCTGTAGGAAAAGCTTGAATTCTTCACTTCTCAGATTCTCAGAGCCAGCTTGCTCTTGGGAGAGGGGCCTGGTATAGGGGCTGCCCAGGTTCGTAGCCTATGCTGTCAAGCATGTTTGGAGTTGCACATCTGTTCCCATGTCATTTTCTCTGTCTAACTGAAGTCAGAAAATTCCTCAGCTGGATTCTGGGGAACCAGGAACCCATATTCCCAAATCCAAGATTGGGACCTGGTTTGTCTTTCCATTTGGGCACATTTCATTCTTTCCAGGAAAACAGGCCACTTCCAACCTGCACAATGTACACCAAACCACAGAACCACAGCTGGGATATGGAGTCAGGAGAGGGAAGCTGGAGCTCAACTCTCATGGACTAAAGGATGGATTCTGGATGGGCTCCAGGGGACACCTTATTGGATTGGTGGCTTCCATCAACTCTTAAAAACGTTAAGTGGTGAACTTTCCCGTCCTGTCAAGCTGTGAATGGGGAATGTATACAAAGTCACTTTGACTTTTCTATTTGAGGCCTCCACAGTAAACATCCAGAGTCATCCTATTTTTGTCTTTTTACCTCCCTTTCAGAACCTGTTTTCGTAATTAGACTGGAAAGCAATTCATGCTAAGTTTGCAATGGCTGCCACAGTTGTAAGTGTCCCCTGCATTTTAACCTGCACTAGAGCCCTAAGCCACAGAGAAGCAGTTCTGAATTGGTATCTCAAATACCATCCACCTGGTGTGGGTCTGCAGGGTGGAGAGCTTTCCCAGCACCCCTGAAGCAATGCCCAATGTCGATTACCTTCTCTGAGTCCTGGCAAGTCCTGGCACATTGGCTTTCTGGATCCCTTAGATGCTGCCCTTTCTGTTGTGAGGAGAGGTTGCCGAAGATATTGGAGGTGTCTGCTGGACTGTAGGATTTCTGATCCCACTGCTGTGTAGTTTTTTTTTCTAGTGCTGGACAAGTAAGAAGCCTCTGGATAAATTTGGTGTTGGTGGCTGATGGTTGAAGTGGAAGCAGTCTTTGGGGTAGGAGGCAATGCCACTCCTCTAGGCCCTTCGGGAGTTGGCTGAAGTTACTTCCTCCCTTGGAAGGGGCTGGTTAGTGAGTGCCAGGGATCTCAGGACTGTCTCTGTGCCAGGTGTGGTTTCCCAGGCAACAGACACATTCCTAAGTGCCTAGTTCTCTAGCGTCTGTATACATGGTAGTAGAGCCTTCCTTCCATGTCTCTCTTCCCTCTGGCCTGGAATAGGAGCATTAGACTCAAATTCTGATGAAAAAGAAATTACTTGGAGATAGAGATTCAATgtgaagagaacaagatatttgaagtcagaattaggtttgaatttgggctcagtgacttacagtgtgagcttggtcaagttcttaacattctggtccttagcattctcatctgtaTGGTCAAGGCTATTGTCATTGGGTTGGTATGTCAACAAGCAAAACGGTATGTGTGAGCTGCCCAATTGTGGGCCTGGTTCTGATTAGCCAATGTTAACACCCTTCTCTCCACAGCTTCCCATTCTCTGATGCCGCTGACCCAGATGGCGTCACCTCAGTTACCATGGCTTGGTCCAAGCAGTGACTTCTGTTCATGGGCTCTGGAATTGAGTGGCCAAAAATCTGGAATCCCTACAGTAGGGAGAGTAGCCTTGTCCCTGCCCCACTACAAGTCTGTTCATATGAAGACATACAAAGCCGTCGCCTCTAATCAGTGTTCAAAGGGTCGATTGTGCAACTCACATTCCTCCAGAGAAATTCCCCCAGCTTGTGAGATCTCCAAGAGGGAACACGTATTCCTGGCATCCAACTTCCCCTGGTGCTCCCCCTGACCTGCCTCATTCCAGGAGTTCCCTCTCCAGAGACCCTGTGTGCCCACACGAGCAGACTTTTAGAAAATGGCCTACAGTTCAAAGGCCCTGCATTGCTTTATGGCCTTGGAAATGTGGGGAAAGTGTCAGATGAAGAATTTCTATCCTCCTCACCTCCTCCCTGTCtccaataaatgcataccaaga

Publications

PMID - Link Title
No publications available for this retrocopy