Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HORMAD1P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:72598241-72599690  UCSC
Coordinates (T2T) chr6:73774910-73776359  UCSC
Coordinates (hg19) chr6:73307969-73309418  UCSC
Strand -
Parental Sequence NM_032132.5
Parental seq. overlap 1352 bp
Parental seq. overlap (%) 70.8%
Genomic Region Intergenic
Retrocopy Summary HORMAD1P1, located on chr6:72598241-72599690, is a retrocopy of the parental gene HORMAD1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HORMAD1
Full Name HORMA domain containing 1
Also known as CT46|NOHMA
Coordinate chr1:150698060-150720910
Strand -
Gene summary This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HORMAD1P1
Bonobo Pan paniscus HORMAD1P1
Gorilla Gorilla gorilla HORMAD1P1
Orangutan Pongo abelii HORMAD1P1
Gibbon Nomascus leucogenys HORMAD1P1
Golden snub-nosed monkey Rhinopithecus roxellana HORMAD1P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HORMAD1P1
TCCGGCGCCTGCCCCTCAGACATAATTTTGAATTAAAGAAAATATTTTATCAGAAGATGGCCACTGCCCAGTTGCAGAGGACTTCCATGACTGCACTGGTATTTCTCAATAAGATACCACCTGAACACCAGTCTTTGGTGTTAGTGAAGAGTTTCCTCACAGTTTCAGTATCCTGTATCATGTATTTGAGAGGAATATTTCCAGCATGTGCTTATGGAACCAGATATCTAGATGATCTTTGTGTCAAAATACTGAGAGAAGATAAAAATTGCCCAGGATCTACACAGTTAGTGAAATGGATACTAGGATGTTACGATGCTTTACAGAAAAAAATATCTAAGCATGGCTGTTCTAGCTATATACACAAACCCAGAAGATCCTCAGACAATTTCAGAATGTTACCAATTCAAATTCAAATACACCAATAATGGACCACTTATGGACTTCATAAGTGAAAGCCAAAGCAATGAGTCTAGCATGTTATGTACTGACACCGAGAAAGCAAGCACTCTCCTAATTCGCAAGATTTATACCCTAATGCAAAATCTGGGGCCTTTACCTAATGTTTGTTTGAGCATGAAACGTTTTTACTATGATGAAGTTACACCCCCAGATTACCAGCCTCCTGGTTTTAAGGATGGTGATTGTGAAGGAGTTATATTTGAAGGGGAACTTATGTATTTAAATGTGGGCGAAGTCTCAACACCTTTTCCCACCTTCAAAGTAAAAGTGACCACTGAGAGAGAACGAATGGAAAATATTTATTCAACTATACTATCACTAAAACAAATAAAAACACAACTTCACAAAATCCTGAGGGACAAAGATGCAGAAGATGACCAGGCGCATTATACAAGTGATGATTTGGACATTGAAACTAAAATGGAAGAGCAGGAAAAAAAAAACCCCTCGATTTTCTGAACTCGGAGAACCAAGTTTAGTTTGGGAGGATGATGAAATTGTGAGGTATAAAAAAAGTTCAGATCTTTCCATTTCTCATTCTCAGGTTGAGCAGTTAGTCAATAAAACATCGGAACTTGATATGTCTGAAAGCAAAACAAGAAGTGGAAAGTCTTTCAGAATAATGGCAAATGGAAATCAACCAGTAACATCTTCCAAAGAAATTCGGAAGAGAAGTCAACATGAATCTGGGAGAATAGTGCTCCATCACTCGCATTCTTCTAGTCAAGAGTCAGTACCAAAAAGGAGAAAGTTTAGTGAACCAAAGGAACATATATAAAAATTATTTTTCTTCTGTATGTTTGCAAAGTTTTTCTCAACATTTAAACTGAAGGACACTATATTATATTTCCCTAACTCTGAAAACGTATATGTAGTTTAAAGCAGTTTGTACACTAAAATTAAGTTCTTGGCTGACTGTCATACTGTGTTCCTTAATCTTGAAATGAATCCAGCAGAACTTTTGAATAAAAGCAAAAGTACACATGTT
>NM_032132.5
GACCGTTGAAGGAAAGCGCATGCGCGTCGGGCACAGCGCGTGCAGCCTCGTGCAGCTCTTCTGGTCTCCGGCGCCCGCCCCTCAGACGTAATGTTGAATTAAAGAAAATACTTTATCAGAAGAAGATGGCCACTGCCCAGTTGCAGAGGACTCCCATGAGTGCACTGGTATTTCCCAATAAGATATCAACTGAACACCAGTCTTTGGTGTTAGTGAAGAGGCTTCTAGCAGTTTCAGTATCCTGTATCACGTATTTGAGGGGAATATTCCCAGAATGCGCTTATGGAACAAGATATCTAGATGATCTTTGTGTCAAAATActgagagaagataaaaattgcccaggatctacacagttagtgaaatgGATGCTAGGATGTTATGATGCTTTACAGAAAAAATATCTAAGGATGGTTGTTCTAGCTGTATACACAAACCCAGAAGATCCTCAGACAATTTCAGAATGTTACCAATTCAAATTCAAATACACCAATAATGGACCACTCATGGACTTCATAAGTAAAAACCAAAGCAACGAATCTAGCATGTTGTCTACTGACACCAAGAAAGCAAGCATTCTCCTCATTCGCAAGATTTATATCCTAATGCAAAATCTGGGGCCTTTACCTAATGATGTTTGTTTGACCATGAAACTTTTTTACTATGATGAAGTTACACCCCCAGATTACCAGCCTCCCGGTTTTAAGGATGGTGATTGTGAAGGAGTTATATTTGAAGGGGAACCTATGTATTTAAATGTGGGAGAAGTCTCAACACCTTTTCACATCTTCAAAGTAAAAGTGACCACTGAGAGAGAACGAATGGAAAATATTGACTCAACTATACTATCACCAAAACAAATAAAAACACCATTTCAAAAAATCCTGAGGGACAAAGATGTAGAAGATGAACAGGAGCATTATACAAGTGATGATTTGGACATTGAAACTAAAATGGAAGAACAGGAAAAAAACCCTGCATCTTCTGAACTTGAAGAACCAAGTTTAGTTTGTGAGGAAGATGAAATTATGAGGTCTAAAGAAAGTCCAGATCTTTCTATTTCTCATTCTCAGGTTGAGCAGTTAGTCAATAAAACATCTGAACTTGATATGTCTGAAAGCAAAACAAGAAGTGGAAAAGTCTTTCAGAATAAAATGGCAAATGGAAATCAACCAGTAAAATCTTCCAAAGAAAATCGGAAGAGAAGTCAACATGAATCTGGGAGAATAGTCCTCCATCACTTTGATTCTTCTAGTCAAGAGTCAGTGCCAAAAAGGAGAAAGTTTAGTGAACCAAAGGAACATATATAAAAATTATTTTTGTTCTGCAGGCTTGCAGAGTTCTTCTCACCATTTAAACTGAAGGACCCTATATTATATTTCCCTAACTCTGAAGATGTATATGTAGTTTAAAGCAGTTTGTACACTAAAACTAAGTTTTTGGCTGACTGTCATATTGTGGTCCTTAATCTTGAGATAAATCCAATAGAACTTTTGAATAAAAGCAAAAGTACAAATGTCATAATTGATTCGGTAATAAGTAAAATTTCAAAATTGATTTTGTTCATTACCTACTTAATATTTCCTTTAAATATATACTAACTGTTAAGGCCCTCTAATGCCATTTTTCTAAACAGTAATGTTTACTTTGGTATTAAAATTTGGTATGGATTCACTTTTTACTTATGTTAAAATTATACCATTTAACTGGCTCTTTTGTCATTGTGCTGTTATTAAAACAATGTTCTTCAATATTTTGACATAATGTATTAACATTTTAATATATAATGTACAATTTAAGAATTGGTGCTTTACCTTTACTATGCTTTTTTTTACAGGACAAAAAGACTGATTTTTAAAGTATGGCATTTTTTGCAGCATAAATAAAATATTGTTCAGTACGTA

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