Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RBPMS2P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:73156721-73158158  UCSC
Coordinates (T2T) chr6:74333348-74334785  UCSC
Coordinates (hg19) chr6:73866444-73867881  UCSC
Strand -
Parental Sequence NM_194272.3
Parental seq. overlap 1271 bp
Parental seq. overlap (%) 62.2%
Genomic Region Intragenic (KCNQ5)
Retrocopy Summary RBPMS2P1, located on chr6:73156721-73158158, is a retrocopy of the parental gene RBPMS2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RBPMS2
Full Name RNA binding protein, mRNA processing factor 2
Also known as -
Coordinate chr15:64739891-64775589
Strand -
Gene summary The protein encoded by this gene is a member of the RNA recognition motif (RRM)-containing protein family and is involved in the development and dedifferentiation of digestive smooth muscle cells. The encoded protein functions as a homodimer and indirectly inhibits the bone morphogenetic protein pathway. [provided by RefSeq, Aug 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RBPMS2P1
Bonobo Pan paniscus RBPMS2P1
Gorilla Gorilla gorilla RBPMS2P1
Orangutan Pongo abelii RBPMS2P1
Gibbon Nomascus leucogenys RBPMS2P1
Green monkey Chlorocebus sabaeus RBPMS2P1
Crab-eating macaque Macaca fascicularis RBPMS2P1
Rhesus Macaca mulatta RBPMS2P1
Baboon Papio anubis RBPMS2P1
Golden snub-nosed monkey Rhinopithecus roxellana RBPMS2P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RBPMS2P1
ACCAGGAGCAACCTGTAGCGGGAGGGCGAGCGCGGCGGCAGCACCTGTACTGGCTCCAGCGCGGGTTCCGGCGGCGTCCTGGAAGAGGAGGTCCGGACACTATCAGCGGCCTCCCCATGGACATTAAACCCAGAGAACCCTACTTGATCTTCCGGCCGTTCAAGGGGTATGAAGAGTCCCTACTCAAGCTCACCGCGAGACAGCCTGTTTTGTGATCTTTGACAGCGGGGCAGGAGCAGAAGCGGCCAAAAATGCGCTGAACGATATTCGCTTAGATCCCGAAAACCCACAGATCATGAGGCTAGAGTTTGCCAAAGCCAACACCAAGATGGCCAAGAGCAAGCTAATGGCAACTCCAAATCCCACCAACATGCACCCCACCTAGGAGCACACTTACTTCATCGCTCGGGACCCCTATGACCTGATGGGGGCTGCTCTGATGCCTGCATGCCCAGAGGCCTGGGCCCTTATCCTTTGTACACCACAGAGCTGACCCCAGCCATCACCCATGCTGCGTTCACCTACCCAGCTGCCACTACCGTTGCCGCCGCCCTCCATGCCAGGTGCGCTGGTTCCCTTCCTCTGACACCACCCAGCAAGGATGGAAGTATCGTCAGTTCTGTTAGTTCTTCAGTCTGGTCACCGGGGAGTTGGTTCTGGGAATCTGTGGTGGTGCCGGGACAGGCGCCCTGAGCTCCCACCGCCCCCGCCCCCGGGCGGCCTGTGCAGAGCTGCCGCTGCCCCCCAGAAATTGTGAATCCTAAGCCTGACACAGTGGACTCCTTCCTGTTTCCCCTTCCTCCTCTTCCTCAGCCCTTTTCTGCACACTCAAGCCTTTCTCCAACGCCTCCCAGGAGGATTTGGGGACCTTCTCGCTGAGGCGCTCAGATCCAGCTCGGAGGATCACTTGGACCCTGCAAGGCCTGACCTCCCACCCAACTTTGCTTCGGTAGCTCCCGCTCGAGGAAACGAGGCGTTTAATTTTGCATGTTTCCTGGCACGAATGAAGACGCTTACGCTTGTGTATATGTGAGTGTACAGTTTGTTTTCACGCTGTCACCATAGCAACAGGTCCTGGCCCCCGGTGGTTCATCCTGCCTGGCCTCTCTCTGCTCGCCTCGCCCCTGCACCCACCACGCTTCAGGGAGGCCCGAGCCCCCAGCCCCGTGGCCCCACACGCTTCCAGACTCAGCGCCTGCCTCCACCCAACAGATAGATGGCATTTGCCTTTTCCTTTCAAATTGGGCTTCTCTGCTCCTATCTCCTCGGATGCGCCAACAGTCATAGGAATGCCCTCTCTGCCGTACTGTTCACCTCTCCACAGTCACTCTGCCTGCCGCTGCTCCTCATTCTTTCCAAACCTTGAATCAACCAAAACGTGAAAAGTATTTTTGTACTCTGTAACAAAATATTTATGCATCG
>NM_194272.3
gcactcgccgGTCGCAGTGAAAAGGCGGAGGCGGCGGcccctccggctcccactgcctcccccgccgcaccccctccccACCTTCCGCACCCGCCAAACTTGATGTGACCCTGGCCCGACGCGGAGGCTGCCCCTCTCACTGCCCCGTGGGTCCCCCGCCACCCGCTCCGCACCCGCGAGCGCACCGCTCCCCGCGCCCCTTCCCACTTCCCGCGGGGCCGGCGCCGCGCTCGCCCTCGCGTTCCTTCCCGCCGCCCCCTCCCCCGCACCATGAGCAACCTGAAGCCGGACGGCGAGCAcggcggcagcaccggcaccggctccggcgcgggctccggcGGCGCCCTGGAGGAGGAGGTCCGGACACTGTTTGTCAGCGGCCTCCCTGTGGACATTAAACCCAGAGAACTCTACTTGCTCTTCCGGCCGTTCAAGGGGTATGAAGGGTCCCTGATCAAGCTCACTGCAAGACAGCCTGTTGGTTTTGTGATCTTTGACAGCCGTGCAGGAGCAGAAGCGGCCAAGAATGCGCTGAACGGTATTCGCTTTGATCCCGAAAATCCACAGACTCTGAGGCTAGAGTTTGCCAAAGCCAACACCAAGATGGCCAAGAGCAAGCTAATGGCAACTCCAAATCCCAGCAACGTGCACCCCGCCCTAGGAGCACACTTCATCGCACGGGACCCCTATGACCTGATGGGGGCTGCTCTGATCCCTGCATCCCCAGAGGCCTGGGCCCCCTACCCTTTGTACACCACAGAGCTGACCCCAGCCATCTCCCATGCTGCGTTCACCTACCCAActgccactgccgctgccgccgccctccacgctCAGGTGCGCTGGTACCCTTCCTCTGACACCACCCAGCAAGGATGGAAGTACCGTCAGTTCTGTTAGTTTTTCAGTCTGGTCACCGGGGAGGTGGTTCTGGTAATCTGTGGTGGTGCCGGGACAGGCGCCCCGAGTTCCCACTGCCCCCGGGCGGCCTGCACAGAGCTGCTGCCCTCCAGAGACTGTGAATCCCAAGCCTGACTCAGTGGACTGCTTCCTGTTCCCCTCCCTCCTCTTCCTCACCTTGTTCTGCACCCTCAAGCCTTTCTCCAATGCCTCCCAGGAGGATTTGGGGACTTTCTCCCTGGGGCGCCCAGATCCAGCTCGGAGGCCTCACTGGGACCTGGCAAGGCCTGACCTCCCGCCCAAACTTGCTTCTGTAGCTCCCCCTCGAGGAAGTGAGGTGTTTAATTTTGCATGTTTTCTGGCATGAATTAAGACACTTATACTTGTATATATGAGTGTACAGTTTGTTCTCACACTGTCACCATAGCGACAGGTCCTGGCTCCCAGTGGTTCATCCTGcctgcccctctctcctcgccccgcccctgcacccaccccgcTTCAGGGAGGCCCAAGTTCCGTGGCCCCACACGCTTCCAGGCTCAGCTCCCACCTCCACCCAACAGATAGATGGGGTTTGCTTTTTCATTTCACATGGGGCTCCTCCGCTCCTGCCTTCTCGGATGGGCCAACAGTCGTAAGAAAGCCCTCTCTGCCCGTTCTGTTCACCTCTCCACAGCGCACCCCGCCCGCCGCTGCTCCTCATTCTTTCCAAACCTCGAAACCAACCAAAACGTGAGAAGTATTTTTGTACCCTGTGTAACAAAATATTTATGCATCATAAAGGATTTTTCATGTGCGTACCATTAATTATTAAAGCGACCTCGTTCGCCCTGTCAGATAAGTTTAATGTTTAGTTTGAGGCATGAAGAAGAAAAGGGTTTCCATTCTTCAGCAGTACGCCTTTGTGTCTGGCATTTGTTTAAGAAAATGAAATGAAGGAAACACTGTGCAATGTTTTTTGTTTTGAGCATATCAGTGCTTTACTGTCAGCCGCAGCTGTGACCGTCTGGCCATTTCAGACTTGGGAGATGAGGCGGCTGTTGTCATTGCTGATCCTGTGAGAATGTGAAACTGGATAATATATGAAATGCAAAATAAAACAAAACCAAAATGA

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