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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TXNP7
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:74004457-74004804  UCSC
Coordinates (T2T) chr6:75182753-75183100  UCSC
Coordinates (hg19) chr6:74714173-74714520  UCSC
Strand -
Parental Sequence NM_003329.4
Parental seq. overlap 298 bp
Parental seq. overlap (%) 40.3%
Genomic Region Intergenic
Retrocopy Summary TXNP7, located on chr6:74004457-74004804, is a retrocopy of the parental gene TXN. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TXN
Full Name thioredoxin
Also known as TRDX|TRX|TRX1|Trx80
Coordinate chr9:110243810-110256507
Strand -
Gene summary The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TXNP6
Bonobo Pan paniscus TXNP6
Gorilla Gorilla gorilla TXNP6
Orangutan Pongo abelii LOC100459927P1
Gibbon Nomascus leucogenys TXNP2
Green monkey Chlorocebus sabaeus TXNP8
Rhesus Macaca mulatta TXNP6
Baboon Papio anubis TXNP6
Golden snub-nosed monkey Rhinopithecus roxellana TXNP3
Mouse lemur Microcebus murinus TXNP1
Crab-eating macaque Macaca fascicularis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TXNP7
TGCTTCTCAGGAAGCCTGGACAGCGCAGGAGATAAACTCATAGTAGTTGCCTCTTTAGACTCGTGGTGCAGGCCTTGCAAAATGATCAAGCCTTTCTTGCATTCTCTCTCTGAAAAGTATACCAGAGTGGTGTTCCTTGAGGTAGATATAGATGGCTGTCAGGATGTTACTTCAGAGTGGAAGTCTAATGCATGCCAACTTTCCACTTTTTAAAAACGGAATAAAAGGTGAGTGAATTTTCTGGAGCTAACAAAGGAAAATTTGAAGGCACCATTAATGAATTAATCTAACCATGTATTCTGAAAACATAACCAGCCAATGGATGTTTAAAACACATAATTTTTTTAC
>NM_003329.4
GAAGCTCTGTTTGGTGCTTTGGATCCATTTCCATCGGTCCTTACAGCCGCTCGTCAGACTCCAGCAGCCAAGATGGTGAAGCAGATCGAGAGCAAGACTGCTTTTCAGGAAGCCTTGGACGCTGCAGGTGATAAACTTGTAGTAGTTGACTTCTCAGCCACGTGGTGTGGGCCTTGCAAAATGATCAAGCCTTTCTTTCATTCCCTCTCTGAAAAGTATTCCAACGTGATATTCCTTGAAGTAGATGTGGATGACTGTCAGGATGTTGCTTCAGAGTGTGAAGTCAAATGCATGCCAACATTCCAGTTTTTTAAGAAGGGACAAAAGGTGGGTGAATTTTCTGGAGCCAATAAGGAAAAGCTTGAAGCCACCATTAATGAATTAGTCTAATCATGTTTTCTGAAAATATAACCAGCCATTGGCTATTTAAAACTTGTAATTTTTTTAATTTACAAAAATATAAAATATGAAGACATAAACCCAGTTGCCATCTGCGTGACAATAAAACATTAATGCTAACACTTTTTAAAACCGTCTCATGTCTGAATAGCTTTCAAAATAAATGTGAAATGGTCATTTAATGTATTTTCCTATATTCTCAATCACTTTTTAGTAACCTTGTAGGCCACTGATTATTTTAAGATTTTAAAAATTATTATTGCTACCTTAATGTATTGCTACAAAAATCTCTTGTTGGGGGCAATGCAGGTAATAAAGTAGTATGTTGTTATTTGTTA

Publications

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