RCPedia: Rtcs

Summary

Retrocopy Name	KPNA4P65	Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr6:85286246-85293027 UCSC
Coordinates (hg19)	chr6:85995964-86002745 UCSC
Strand	+
Parental Sequence	NM_002268.5
Parental seq. overlap	3030 bp
Parental seq. overlap (%)	33.1%
Genomic Region	Intergenic
Retrocopy Summary	KPNA4P65, located on chr6:85286246-85293027, is a retrocopy of the parental gene KPNA4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	KPNA4
Full Name	karyopherin subunit alpha 4
Also known as	IPOA3\|QIP1\|SRP3
Coordinate	chr3:160495007-160565571
Strand	-
Gene summary	The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	KPNA4P1
Bonobo	Pan paniscus	KPNA4P1
Gorilla	Gorilla gorilla	KPNA4P1
Orangutan	Pongo abelii	KPNA4P1
Gibbon	Nomascus leucogenys	KPNA4P1
Baboon	Papio anubis	KPNA4P1
Golden snub-nosed monkey	Rhinopithecus roxellana	KPNA4P1
Green monkey	Chlorocebus sabaeus	Without Homology
Crab-eating macaque	Macaca fascicularis	Without Homology
Rhesus	Macaca mulatta	Without Homology
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>KPNA4P65
GAGTTAAATTAAGGAAGAATAAAAGAGATGAACATCTCTTAAAGAGAAGGAATGTACCACATGAAGATATCTGTGAAGAGTCTGATATTGATGGTGATTATAGAGTGCAAAGTAACTCTCTAGAAGCTATTGTTCAAAATGTTTCAAGTGATAATCAACGAATTTAATTAAGTGCAGTTCAAGCTGCCAGGAAGCTTTTATCCAGTGATCGAAATCCACCAATTGATGACTTAATAAAATCTGGAATATTGGCCATTTTAGTCCATTGTCTTGAAAGAGATGACAATCCTTGTTTACAGTTTGAAGCTGCATGGGCTTTGACAAATATTGCATTTGGAACTTCTGAACAAACTCAAGCAGTAGCTCAGTCCAGTCCAATGCTGTGCCACTTTTCCTGAGGCTTCTCCATTCACCCCATCAGAATGTCTGTGAGCAAGCAGTGTGGGCATTGGGAAATAGCATAGGTGATGGGCCCCAGTGTAGAGATTATGTCATAAGTCTGGGAGTTGTGAAACCTTTACTTTCCTTCATAAGTCCAACTATTCCTATAACAAACATTCTTAAGAAATGTTACTTGGGTTATGGTCAACTTATGTCGCCACAAAGACCCACCACCACCAATGGAAACCATTCAGGAGATTCTTCCAGCCCTTTGTGTTTTAATTCATCACATAGACGGAAGTTAAAGTTCAGACTGCTGCACTTCGAGCTGTGGGCAACATTATTATGGGAACTGATGAGCAAACACAAGTAGTGTTGAACTGTGATGCCCTTTTACACTTCCCAGCACTCCTGACACATCCCAAAGAGAAAATCAATAAAGAAGCAGTGTGGTTCCTCTCTAATATCACTGCAGGAAGTCAGCAGCAGGTACAGGCAGTAATTGATGCCAATCTTGTACCAGTGACAATACATCTTTTGGATAAGGGGATTTTGGCACTCAGAAAGAAGCTGCTTGGGCCATAAGTAACTTAAAAGTTAGTGGAAGGAAAGATCAAGTGGCTTACCTTATCCAGCAGAATGTTATCCCACCTTTTTGCAACTTGCTGACTGTAAAAGATGCACAAGTGGTCGTCCGCAAAGCCTGAGTCCTGTCCTCTCACTCTCCTCCCCAGACAGCATGAGCTTCAACACTTGctccaccttctccacctgctccaccttctccaccAACTACCAGTCCCTGGGGCGCCTGGACATGCAGAGGCAAAAAAAAAAAAAGATGCACAAGTTGTGCAGGCAGTACTCAATGGACTAAGTAATATACTAAAAATGGCCAAAGATAAGGCATAAACCATGGACAATCCAGCCAGGCAATCTTATAGAAGAAGATGGAGGGCTGGAGAAAATTAAACAACTTCAAAATCATGAAAATGAAGACATCTACAAATTGGCCTATGAGATCATTGATCAGTTCGTCTGTTCAGATGATAATTGATGAAGACCCTAGCCTTGTTCCAGAGGCAATTCAAGGCGGAACATTTGGTTTCAATTCATCTGCCAATGTACCAACAGAAGAGTTCTAGTTTTAGAAAGACGTCATGGAAGTTAGGTACAATGCAGCACTGAGCAAAGTTTTGATCCATCAAGCTTGGCTCGTGGGATCTGCTGCTGCATTAAATATAAATAGGGAAATAAAATGTGAAGATTTCATTTGAAATCACAGAAAATGCCCAAATGAGGTCAAGATGGAGAATGGGTGCAAGTGAGAATGAGTGGCAAAATGTAATGGAAACTTCACATGAATGCTTATTTACGTTGTTCAAAGTAAAAAGGGCTACAGGTCACAGATCATCAGTGCCTGAGAAAGAACACTGACTTGCTTTATATCAATTGAGGGGAAAGTGCAGTACTGTGATCTTCAACCTTGTAAGCATAAAAGAGAATAGGCTGCCTGTATAAGTCAAAGGAAAATAGGCCAAGGCCTTGTTATGAAGCAATGTGTGAATGGACAATGTTGAATGAATGTCTGGGTCAGTGATGGAGAGCCAGGTTCGTCTTTAAAATCTAGGGCTCGTCACTTATGAAGCAGACTCCTAGTACTGGAGTGACTCTATATGAGAGTGTGGTTGTGGTGCTGTATGTGAACTCATGTAAGCTTGATTCACCTTCAGGGGCTGATAACAAACCTAGTAAATCATCAAAATGAGATAATAAGTGCTAATGTACACTGGACATGAAAACAAAGACTGGTTTAGCAGCAGACATTGGTTTACTCTACAGCTTGTGTTTTCTATTTCCCCCTTTCCCACCTCCTTCCCCCTACCCAACTCCtACCTAGTGTGCCTTTTTTTAGTTGCTTCTCAAGTCAGGAAACTTTACAGGAAGGATTCCCTGTGCATTTGCACCAGATGAATGTTTGATGCTATGAAAAACTTTCCATAGCATCAAAACTAATTTGTGTAGATTTTTGCATAAAAAAATCATAAATTTCCCTCAAAGTAGACTGTGTTGCAGTACACAAGTTGCCATAATAGTAAAAAACAGTAAAATGTGCTTAAAAGGCCATCTTTTTCATTTTCAGAGATATCATAAAGATGTTTGCATGAGGTAAATCTATAGCATAGTTCATTTTTAGGTTTTGTTGAGTCCTGTAAAGAAGAAGAAAAAAAAGTTTCAGCTGTGGTAGAATACCATGCTGTGTTTAAATGTTACTTGTTTTCAAACTTTCTTTTCTATGAAAATGACATGGAAACTTCTAAAATGGAATTTGGTGTATATGTACTGCTGAATAAAGACCAATGAAGAGGTTTGAGTAGATGTACAAATCAAGTAATGGTTTGAACACCTTTAATAATATGCCTAATCTGTTCCATTGTTTCAGAATCTTTTTATCTTAGATGTAGGCAACCATGAACAATCTATTTTGAGCCCCTTTAGGGAGAAAACTTTGTATTTTTAAAACTTGCATAAAAGTTATGCAAGTGGTTTTTATAAATCAGAATAATACCTCAGTTTTGATGTTATGCACACTAAATTAAATGTGACATAAATTAATTTGTACAAAAAGAACTAGGTGGCTCATTGTAAGAAATCCTGTGCCTTCCCCTTTGAGCACAAGTGTTGCATGAACAACAGTTTGCTATAAGAAACATACCAGATTAGCCACCATTAGCATCTATATCTACTTTGTGTTTAAAAATCAACTGGTAATTCTGAAACACTGTAGAATAGATAAAAATTATTTTGTGATCATAACTCTTTGTTGAACTAGAGTATTTTTGCAACATTCCTTGTCATCAGAATAATGGTTAAAGTTTAAAACTAGAAGCAGCAGAAAACTAGCTTGTAAAATGTATCCAAGTAAAGTGCAGGCTAGGCTGTCTTGGGGAAATAAACATTAAAACTTAAAGCAATGTT

>NM_002268.5
AGATCGAGGCTGCCTCCCCCTCTCAGCCGGCAGCACATTCCGTCGCCTTGCCGCCGCCCGGCCCCACAGTTGTCTTTGCCGGAGCTGCAGTCGCGCTGGGGTTAGGGCGGGGGGGCGGGCGGGGAGAGGAGAAGGCCGCGGCGGAGGCAGGTGAGAGGAGGAAGGAAGCGGCGGCGCGGCGGGCACAGCAGCTCAGGCGGCGGCCCGGTTCCTGGGAGTGTCGGTGCGGCGCGTTGGTTGGGGCGGATCCCGCGGGGCCCGGGCGGGGGAAGGAGTCACCGGCCCGGCCATGGCGGACAACGAGAAACTGGACAACCAACGGCTCAAGAATTTCAAGAACAAAGGCCGCGACTTGGAGACTATGAGAAGACAACGAAATGAAGTTGTAGTTGAATTAAGGAAGAATAAAAGAGATGAACATCTCTTAAAGAGAAGGAATGTACCACATGAAGATATCTGTGAAGACTCTGATATAGATGGTGATTATAGAGTGCAAAATACCTCTCTAGAAGCTATTGTTCAAAATGCTTCAAGTGATAACCAAGGAATTCAATTAAGTGCAGTTCAAGCTGCTAGGAAGCTTTTGTCCAGTGATCGAAATCCACCAATTGATGACTTAATAAAATCTGGAATATTGCCCATTTTAGTCCATTGTCTTGAAAGAGATGACAATCCTTCTTTACAGTTTGAAGCTGCATGGGCTTTGACAAACATTGCATCTGGAACTTCTGAACAAACTCAAGCAGTAGTTCAGTCCAATGCTGTGCCACTTTTCCTGAGGCTTCTCCATTCACCCCATCAGAATGTCTGTGAGCAAGCAGTGTGGGCATTGGGAAATATCATAGGTGATGGGCCCCAGTGTAGAGATTATGTCATAAGTCTTGGAGTTGTGAAACCTTTACTTTCCTTCATAAGTCCATCTATTCCTATAACATTCTTAAGAAATGTTACTTGGGTTATGGTCAACTTATGTCGCCACAAAGACCCACCACCACCAATGGAAACCATTCAGGAGATTCTTCCAGCCCTTTGTGTTTTAATTCATCACACAGATGTAAATATACTGGTAGACACAGTCTGGGCCCTCTCTTACCTTACTGATGCTGGCAATGAACAAATACAGATGGTAATAGACTCTGGAATAGTTCCTCATTTGGTTCCTCTGCTCAGCCACCAGGAAGTTAAAGTTCAGACTGCTGCACTTAGAGCTGTGGGCAACATTGTTACTGGAACTGATGAGCAAACACAAGTAGTTTTGAACTGTGATGCTCTTTCACACTTCCCAGCACTCCTGACACATCCCAAAGAGAAAATTAATAAAGAAGCAGTGTGGTTCCTCTCCAACATCACTGCAGGAAATCAGCAGCAGGTACAGGCAGTAATTGATGCCAATCTTGTACCAATGATAATACACCTTTTGGATAAGGGGGATTTTGGCACTCAAAAAGAAGCTGCTTGGGCCATAAGTAACTTAACAATTAGTGGAAGGAAAGATCAAGTGGCTTACCTTATCCAACAAAATGTTATCCCACCTTTTTGCAACTTGCTGACTGTAAAAGATGCACAAGTTGTGCAAGTAGTACTCGATGGACTAAGTAATATATTAAAAATGGCTGAAGATGAGGCAGAAACCATAGGCAATCTTATAGAAGAATGTGGAGGGCTGGAGAAAATTGAACAACTTCAAAATCATGAAAATGAAGACATCTACAAATTGGCCTATGAGATCATTGATCAGTTCTTCTCTTCAGATGATATTGATGAAGACCCTAGCCTTGTTCCAGAGGCAATTCAAGGCGGAACATTTGGTTTCAATTCATCTGCCAATGTACCAACAGAAGGGTTCCAGTTTTAGAAAGATGTTGTGGAAGTTAGGTACAATGCAGCACTGAGatatatatatatatatgtgtgtgtgtatatatatatatatatacatatatataAAAAGGTTTGATCCATCAAGCTTGGCTCATGGGATCTGCTGCTGCATTAAATCGGGAAAGAAAATGTGAAGATTTCATTTGGAATCACAGAAAATGCCCAAATGAGGTCAAGATGGCGAGTGGGTGCGAGTGAGAATGAGTGGCAAAATGTAATGAAAACTTTACATGAATGCTTATTTAGGTTGTTCAAAGTAAAAAGGGCTACAGGTCACAGATCGTCAGTGCCTGAGAAAGAACATTGACTTACTCTATATCAATTGAGGGGAAAGTGCAGTACCGTCATCTTCAAGCCTTGTAAGCATAAAAGAGAATAGGCTGCCCATATAAGTCAAAGGAAAATGAGCCCAGGCCTTGCTATGAAGCAGTGTGTGAATGGACAATGTTGAATGAATGTCTGGCTCAGTGATGGAGAGCCAGGTTCATCTTTGAAATCTAGGGCTCTTCACTCATGAAGCAGACTCCTAGTCCTGGAGTGACTGTGTACGAGAGCGTGGTTGTGGTGCTGTATGTGAACGCATGCAAGCTTGATTCACCTTCAGGGGGCTGATAACCTAGTAAATCATCAAAATGAGATCATAAGTGTTAATGTACACTGGACATGAAAACAAAGACTGGTTTAGCAGCAGACATTGGTTTACTCTGCAGCCTGTGTTTTCTGTTTCCCCCTTTCCCACCTCCTTCCCCCCACCCAATCCttttttttttcttttttgcttttcttttctttttttttagtttttatttACTTTACCTAGTATGCCTTTTTTTAGTTGCTTCTCAAGTCAGAAAACTTTTCAGGAAGGTTTCCCTGTGCATTTGCACCAGATGAATGTTTGATGCTATGAAAAGCTTTCCATATCATCAAAACTAATTTGTGTAGATTTTTGCATGAAAAAAATCATAAATTTCCCTCAAAATAGACTGTGTTGCAGTACACAAGTTGCCATAATAGTATAAAACAGTAAAATGTGCTTAAAAGGCCATCCTTTTCATTTTCAGAGATAACATAAAGATCTTTGCATGAGGTAAATCTACAGCATAGTTCATTTTTAGATTTTGTTGAGTCCTGTAAAGAAGAAGAAGAAAAAAGTTTCAGTTGTGGTAGAATACCGTGCTGTGTTTAAATGTTACTTGTTTTCAAACTTTGTTTTCTATGAAAATGATATGGAAACTTCTAAAATGGAATTTGGTGCATATGTACTGCTGAATAAAGACCGATGAAGAGGTTTGAGTAGATGTACAAATCAAGTAATGGTTTGAACACCTTTAATAATATGCCTAATCTGTTCAATTGTTTTAGAATCTTTTTATCTTAGATGTAGGCAGCCATGAACAATCTATTTTGAGCCACTTTAGGGAGAAAACTTTGTATTTTTAAAACTTGCATAAAAGTTATGCAAGTGGTTTTTATAAATTGGAATAATACCTCAGTTTTGAGGTTATGCACACTAAATTAAATGTGACATAAATTAATTTGTACAAAAAGAACTCTTTATAAGGTGGCTCATTGTAGGAAATCCTGTGCCTTCCCCTTTGAGCACAAGTGTTGCATGAACAACAGTTTGCTATAAGAAACATACCAGATTAGCCACCATTAGCATCTATATCTACTTTGTGTTTAAAAATCAACTGGTAATTCTGAAACACTGTAGAATGGATAAAAATTATTTTGTGATCATAACTCTTTGTTGAACTAGAGTATTTTTGCAGCATTCCTTGTCATCAGAAACATGGTTAAAGTTTAAAACTAGAAGCAGCAGAAAACTAGCTTGTAAAATTTATCCAAGTAGAGTGCAGGCTAGGCTGTCTTGGGGAAATAAACATTAAAACTTAAAGCAATGTTTTACATGGGgtgtgtgtgtgtggtgtgtgGATTTTTTTTTTTTTATAAAGTTAGAGTATAATTCAATGGCTTACATTAGCTTCCTGTCTTTTTACCTAGAACCAGCATAATAAGAAATTTCTTTGGTTCTGTCATTTCAGTATGGACATATTAATATTTTAGCCCACTGAGTTTGTCCAGTTGACACCATCAGTGCTTCAGTTTTCTCTCTATCCAAAGCAAGGTTTTAACTTTCCTTCATTCTCCAGTAAAACAGACCGAGACAACTTGAACTATATTTTGAGTATTGCTATATCTTCAACATATAGCTCCAAATGATGGATTGTATACAAAGCATAGTACAGAAGGTTTCAGTAATTGGAAGGTGAACACAGCAATGCTTTACATAATTTGTGTTTTTTAGTAAAAAATATTGGATTCAAAGTAAGCCAATGAGCTTGTATACAAATTTTATATACAAATTATTGTATAGAACAGTGATATGGAAAATAGGTAAGGGTGATATTAATATCTCTGGGTATAAGGACTACCTTATCGTTTAAATATTTTATTTCCATCTATAGCCTAATATAGAACATTGATTTTCTAGTAGAAATTCTGGGAAGGGCTTTTCTGTCTCTGAAATTGATTCAGTACAGTTGACAGTTCATCACGGTTACCTGGTTAAACACTTTTTTTTTTTTTTTAATTCTCCAGTGATCTAGGAAATTGTTTCATTTTTAACACAGGCTTATTTCTGATGGGGATGGGGGCATAGAATAATATGCCTAATAAGCTAAACGTTCTTAACGTTTCATGTCTTAAACTGTCTTTTTGAACATTGAGACCACCTCAAGTGCTGTAAAAATAAGAATGTTATATTAGGGGTGTGTGAGACGCCCTAGTCTAAAATCTATCTTTAAATATATTTCCTTTGTAATTTTCAAAGACTTCAGTAATTGTGTGTTATGGTGGAAATAATACTTTCCATTGGTCCACATTGCTCTGGACCAAACCTGGAGCATTTCTATAATTAGAGCTATCTATGAATCATTAAAAATGGATCTAGAATAATTTTGGGGAGAGGGAGTGTATCATTTAGTTTAGGCTTACCTCAGCAGCACTTCATAGGGTGAGGAGTTGTTTGTTTCTTTAAAGGTATAACTGCATTGTAAAATGACTGGGTTTATTGTAACAGTAATTTATGGGGGCACCCTTTTTGGATTCTCCATTGCCTCAGTTTCCTCAAGGAAAAAGTTACAGAGATTAAGCTAAATTTTGAATTTAGAGAATAACTGCTGTGTAATTTTGGTATaattaccataaatttagtgtcttaaaacacaacatacattatttcacaatttctgtaggtcaagagtgtagttaggttttctgctcagggtctcacaaggctgcaataaaggtgtcagccagagctgcagtcttatctgaagctagggggtcctcttttatgcacatatggcaaaatccattgcctagcaactgaagaaATCATGGGAActtcttcaaggccagcaagagaatctctgatctcagggaaggccttaagcgcttttttaaaggtctcacctgattagatcaggccacctacccaccagggtgatctcccttttgattaacccaaagccaaactgatgaggtaccttcattacccctgcaaaatcccttcacctttgccctgcattgtagtccaatcacaggggtgatacgcatcatattcaaagatcctgttcacagtcaagggagggggttatatggagtatgtataccagggaatcttgggagccatcttaagagttcttcctatgacaAGGACTCAACTATTTAGAACTGGAACAATTTACAAGTGATAGCCTTATATAGTTATCATAGCaagcttatttggggatcaaggttgcctctgagaacctaatgaaaactggaccagcttccccaaaaagtgtatataCATGGTAGTTTTTCATACAGTTTTAGGGGATTCATAAGAGTCCATGAATTACAGTCTGTCCCAACCCTTCCCTTTAGATGATGAGTTGTtgaggtgacttgcccaaggtcacacagctactaagggccaaataaagcccacatctcaactcccatactgcccagggcttctaattactaTTCTAAAGGTAATCTAAATTCATTTAAATTTGTGAACCAATGCAAAAAAATGTGAATGTAGCTTTTTGGATATTTTTTTTGTTTACTAAGGAATGGGTAACATTGTTATAGAAGCTTGCCTAAGAGTTTTGAAATTAGTTGACCTTTTTGAGTTTCCAAAATTGAATCTTCCATTGTAGCTATTAAAGTGAACTATAAATAGGCCAACTTTAATTGTTAACTCCTCGGGTTTGGTGGATTATCTACCATTTATATATAAAATTTCAGTTAGAATCCACCATTGGCGTTTTGAAGGCCAAGATAGCTGAGTATCTTATCCTTTTTGTAACTTCTTGATTATTTTACTTATTGGCAAAATTCATTAACTGTCAGCCAATAATTTAATATTATGGGAGGAAAAAATTTTGCCCAGATATCTGAGGCAATACTCCCAAACACTAACAAACTGATGCCTAACAAACTTGACATTTTGAACACTTAAAGTTTTCCCTAAACTTTTTAATAAGCACATTAATAAAGTATGCTTTTAAATATATATGTACAATAATTTTTAAAAGTTGCTGCAAGATGCCTTCAAATCAATATGCACGTTGGTGGCATTAGTGCAGTCTTCTAtttttatttttttgagacacagtctcgctctgtggcccaggctggagtgtagtggcgcaatctcggctcactgcaacctctgcctcaagggttcaagcaattctgcctcagcctcctgagtagctgggattacaggagtacgctaccacgcctggctaatttttgtatttttagtagaaatggggtttcaccgtattggccaggctggtattggaatcctgaccgcaaatgatctgcccacctcggcttcccaaagtgctgggattacaggcgtgagccactgcgcccaaccAGCCTTAATTCTTAATAAAGGAAGTTGAAAAATAATGAACATTGGTAAAACTATTCTAGTGTGATCAGAAGCAAATTTGGACTGTAGTGTCAAATTGATAAAAAACTAAGCACACCAATCATGTATAAGAAAAGTAGATTTAACATTTTTTTCCCTAAACACTTAACCCAGAAGTTAACAATAATCTTGAAAATTCCTTTTAAATCCAGGCCCTTTAGGTGATGGCAGTTTGACTCAGGATGTCCAAGTCCAGTGTATTTTCAATAAAATTGACTTGACAGCTACTGCTCTGGGTGTAAGAGCAGTTGACTGTGAGGAAAAGTAAATGGTTCTACAGATTCTTTATGATCTACCTCCCACCAGAGGACTGCAGTACTCCCTTGTTATTTATATTTTCTGCCCCAATTTTTGCCTTCTCCACAAATTTTATACCTTTTGTAGCTGCCTACTCCAGATTACTTCACCTTTCCAGACTATCAGTTCTTCCACTTTTATTCTTCATAAAGAAAATTCCAATAACCTGTTTCACTTAGGTTTTTCTATTACTCTTCAAGCATGAATCCTAATTTCCCTGACTATATCTTACCTCTGATCTCCATAACTGATGGATTCCTATCCTAGACTATGTTACTCTAATATTACCCAAGATTTTCTCCAGCCTGTTTTTACTCTTACTTTGAAACAGCTGTTTAAAATGACTCGTAATCTGCTTAAATCTACATGCTTTTTGTGGTTCTCAATCCAGTTACCTACCTTCCAGATAATTCCCTCACTGTCCTGTCCTCTCCATTCCTCTGATGTTTAAGCCCTGTGAGCCACCTTTCCCCCATCCTTTGTGCATAGTTACCATTTTACTCTTTCTtgttgcccaggcaggaatgcagtggtgccatcttggctcactgcaacctccacctcctaggttcaagcgattctcctgcctcagcctcctgagtagctgggaccacaagcgtgcaccaccacgcccggctaatttttgtatttttagtagagatggggtttcaccacgttggccaggctggtctcgaactcctgacctcagatgatccaccctccttggcctcccaaagtgctgggattgcaggcgtgagccaccgcctggccACCATTTTACTCTTTTTAGGTACAGTAATCTAATATCCAAAGTCTTGGACTCAGCTAAAGAGGGTATTTACCTTaaaaaaaaaaaaaaaaaGACTCCATCTTTTGATTCATAATTGTGGTGGGGGCGGGGAATCAAGACAACCTTAGTCACTTTGGTATTACCATAATTCTTGTCTTTTCAGGGTTGTCCTGTTCAGCTGCATAAAACATCATGTATTCTAGGTATTTCCTACCTTCACTTACATTTTTACTTGCCGATGTGCTGCCTTCATAAATGGGTATATTCCGCCACACATCTAGTAAGCCCCCAATGCAGTACACAATGTGTATCACTGATAAAACTCGCACTTCTGCCATGTCAGTATTATATTCAGTTGAGTGGTCTTTAGCATAGTGGCAGTCCTAGTCATCCTAACCTTTTAGTTAAGGTAAAATTACATATGTTTATAGAACTCATATAGACAAGCTAGTTTTTAAAATCTTCCTTTTAACCAGTTTAGGATGATCTAGGATAGCTAAGTTACCTACATGGTGACTGTTCGGTCTAATTCAGAAACAGAAGTACTAAAAGAATACTAAAAAGTTTTTACCCATTATCTCTATCCCTGTTTTCTTTTTGCAATTCTCAGCTGCAGGGAGCAAGAAAATACACAGCAGATAGGAAATGTTTGTTTGCATCCTGGCTTTCTCAACCGCACTTTACGTCCTTGAATATTCTAGATATTTACTCCTTCAAGAAGTCAGGAGTATATCCAGGCCTACCTATCATCCTTGCCATCCCCATTAACCCTCATTTTTCAGTATGTGTTTTACATTTATGGTTATTTTTCAGTCTATAGTATCTGTTCACTCATTGCTCTATCACATCTGAgtttctccgtctttctttccactagattgtaagctccttaagggcaaggTCGGCATATAAGCAAAGTTCTGTAAACACCGTGAAGGTACCATGAGTTCTATGGGTACTCAATAAATGCTTGTGATAATGA

>NM_002268.5 

AGATCGAGGCTGCCTCCCCCTCTCAGCCGGCAGCACATTCCGTCGCCTTGCCGCCGCCCGGCCCCACAGTTGTCTTTGCCGGAGCTGCAGTCGCGCTGGGGTTAGGGCGGGGGGGCGGGCGGGGAGAGGAGAAGGCCGCGGCGGAGGCAGGTGAGAGGAGGAAGGAAGCGGCGGCGCGGCGGGCACAGCAGCTCAGGCGGCGGCCCGGTTCCTGGGAGTGTCGGTGCGGCGCGTTGGTTGGGGCGGATCCCGCGGGGCCCGGGCGGGGGAAGGAGTCACCGGCCCGGCCATGGCGGACAACGAGAAACTGGACAACCAACGGCTCAAGAATTTCAAGAACAAAGGCCGCGACTTGGAGACTATGAGAAGACAACGAAATGAAGTTGTAGTTGAATTAAGGAAGAATAAAAGAGATGAACATCTCTTAAAGAGAAGGAATGTACCACATGAAGATATCTGTGAAGACTCTGATATAGATGGTGATTATAGAGTGCAAAATACCTCTCTAGAAGCTATTGTTCAAAATGCTTCAAGTGATAACCAAGGAATTCAATTAAGTGCAGTTCAAGCTGCTAGGAAGCTTTTGTCCAGTGATCGAAATCCACCAATTGATGACTTAATAAAATCTGGAATATTGCCCATTTTAGTCCATTGTCTTGAAAGAGATGACAATCCTTCTTTACAGTTTGAAGCTGCATGGGCTTTGACAAACATTGCATCTGGAACTTCTGAACAAACTCAAGCAGTAGTTCAGTCCAATGCTGTGCCACTTTTCCTGAGGCTTCTCCATTCACCCCATCAGAATGTCTGTGAGCAAGCAGTGTGGGCATTGGGAAATATCATAGGTGATGGGCCCCAGTGTAGAGATTATGTCATAAGTCTTGGAGTTGTGAAACCTTTACTTTCCTTCATAAGTCCATCTATTCCTATAACATTCTTAAGAAATGTTACTTGGGTTATGGTCAACTTATGTCGCCACAAAGACCCACCACCACCAATGGAAACCATTCAGGAGATTCTTCCAGCCCTTTGTGTTTTAATTCATCACACAGATGTAAATATACTGGTAGACACAGTCTGGGCCCTCTCTTACCTTACTGATGCTGGCAATGAACAAATACAGATGGTAATAGACTCTGGAATAGTTCCTCATTTGGTTCCTCTGCTCAGCCACCAGGAAGTTAAAGTTCAGACTGCTGCACTTAGAGCTGTGGGCAACATTGTTACTGGAACTGATGAGCAAACACAAGTAGTTTTGAACTGTGATGCTCTTTCACACTTCCCAGCACTCCTGACACATCCCAAAGAGAAAATTAATAAAGAAGCAGTGTGGTTCCTCTCCAACATCACTGCAGGAAATCAGCAGCAGGTACAGGCAGTAATTGATGCCAATCTTGTACCAATGATAATACACCTTTTGGATAAGGGGGATTTTGGCACTCAAAAAGAAGCTGCTTGGGCCATAAGTAACTTAACAATTAGTGGAAGGAAAGATCAAGTGGCTTACCTTATCCAACAAAATGTTATCCCACCTTTTTGCAACTTGCTGACTGTAAAAGATGCACAAGTTGTGCAAGTAGTACTCGATGGACTAAGTAATATATTAAAAATGGCTGAAGATGAGGCAGAAACCATAGGCAATCTTATAGAAGAATGTGGAGGGCTGGAGAAAATTGAACAACTTCAAAATCATGAAAATGAAGACATCTACAAATTGGCCTATGAGATCATTGATCAGTTCTTCTCTTCAGATGATATTGATGAAGACCCTAGCCTTGTTCCAGAGGCAATTCAAGGCGGAACATTTGGTTTCAATTCATCTGCCAATGTACCAACAGAAGGGTTCCAGTTTTAGAAAGATGTTGTGGAAGTTAGGTACAATGCAGCACTGAGatatatatatatatatgtgtgtgtgtatatatatatatatatacatatatataAAAAGGTTTGATCCATCAAGCTTGGCTCATGGGATCTGCTGCTGCATTAAATCGGGAAAGAAAATGTGAAGATTTCATTTGGAATCACAGAAAATGCCCAAATGAGGTCAAGATGGCGAGTGGGTGCGAGTGAGAATGAGTGGCAAAATGTAATGAAAACTTTACATGAATGCTTATTTAGGTTGTTCAAAGTAAAAAGGGCTACAGGTCACAGATCGTCAGTGCCTGAGAAAGAACATTGACTTACTCTATATCAATTGAGGGGAAAGTGCAGTACCGTCATCTTCAAGCCTTGTAAGCATAAAAGAGAATAGGCTGCCCATATAAGTCAAAGGAAAATGAGCCCAGGCCTTGCTATGAAGCAGTGTGTGAATGGACAATGTTGAATGAATGTCTGGCTCAGTGATGGAGAGCCAGGTTCATCTTTGAAATCTAGGGCTCTTCACTCATGAAGCAGACTCCTAGTCCTGGAGTGACTGTGTACGAGAGCGTGGTTGTGGTGCTGTATGTGAACGCATGCAAGCTTGATTCACCTTCAGGGGGCTGATAACCTAGTAAATCATCAAAATGAGATCATAAGTGTTAATGTACACTGGACATGAAAACAAAGACTGGTTTAGCAGCAGACATTGGTTTACTCTGCAGCCTGTGTTTTCTGTTTCCCCCTTTCCCACCTCCTTCCCCCCACCCAATCCttttttttttcttttttgcttttcttttctttttttttagtttttatttACTTTACCTAGTATGCCTTTTTTTAGTTGCTTCTCAAGTCAGAAAACTTTTCAGGAAGGTTTCCCTGTGCATTTGCACCAGATGAATGTTTGATGCTATGAAAAGCTTTCCATATCATCAAAACTAATTTGTGTAGATTTTTGCATGAAAAAAATCATAAATTTCCCTCAAAATAGACTGTGTTGCAGTACACAAGTTGCCATAATAGTATAAAACAGTAAAATGTGCTTAAAAGGCCATCCTTTTCATTTTCAGAGATAACATAAAGATCTTTGCATGAGGTAAATCTACAGCATAGTTCATTTTTAGATTTTGTTGAGTCCTGTAAAGAAGAAGAAGAAAAAAGTTTCAGTTGTGGTAGAATACCGTGCTGTGTTTAAATGTTACTTGTTTTCAAACTTTGTTTTCTATGAAAATGATATGGAAACTTCTAAAATGGAATTTGGTGCATATGTACTGCTGAATAAAGACCGATGAAGAGGTTTGAGTAGATGTACAAATCAAGTAATGGTTTGAACACCTTTAATAATATGCCTAATCTGTTCAATTGTTTTAGAATCTTTTTATCTTAGATGTAGGCAGCCATGAACAATCTATTTTGAGCCACTTTAGGGAGAAAACTTTGTATTTTTAAAACTTGCATAAAAGTTATGCAAGTGGTTTTTATAAATTGGAATAATACCTCAGTTTTGAGGTTATGCACACTAAATTAAATGTGACATAAATTAATTTGTACAAAAAGAACTCTTTATAAGGTGGCTCATTGTAGGAAATCCTGTGCCTTCCCCTTTGAGCACAAGTGTTGCATGAACAACAGTTTGCTATAAGAAACATACCAGATTAGCCACCATTAGCATCTATATCTACTTTGTGTTTAAAAATCAACTGGTAATTCTGAAACACTGTAGAATGGATAAAAATTATTTTGTGATCATAACTCTTTGTTGAACTAGAGTATTTTTGCAGCATTCCTTGTCATCAGAAACATGGTTAAAGTTTAAAACTAGAAGCAGCAGAAAACTAGCTTGTAAAATTTATCCAAGTAGAGTGCAGGCTAGGCTGTCTTGGGGAAATAAACATTAAAACTTAAAGCAATGTTTTACATGGGgtgtgtgtgtgtggtgtgtgGATTTTTTTTTTTTTATAAAGTTAGAGTATAATTCAATGGCTTACATTAGCTTCCTGTCTTTTTACCTAGAACCAGCATAATAAGAAATTTCTTTGGTTCTGTCATTTCAGTATGGACATATTAATATTTTAGCCCACTGAGTTTGTCCAGTTGACACCATCAGTGCTTCAGTTTTCTCTCTATCCAAAGCAAGGTTTTAACTTTCCTTCATTCTCCAGTAAAACAGACCGAGACAACTTGAACTATATTTTGAGTATTGCTATATCTTCAACATATAGCTCCAAATGATGGATTGTATACAAAGCATAGTACAGAAGGTTTCAGTAATTGGAAGGTGAACACAGCAATGCTTTACATAATTTGTGTTTTTTAGTAAAAAATATTGGATTCAAAGTAAGCCAATGAGCTTGTATACAAATTTTATATACAAATTATTGTATAGAACAGTGATATGGAAAATAGGTAAGGGTGATATTAATATCTCTGGGTATAAGGACTACCTTATCGTTTAAATATTTTATTTCCATCTATAGCCTAATATAGAACATTGATTTTCTAGTAGAAATTCTGGGAAGGGCTTTTCTGTCTCTGAAATTGATTCAGTACAGTTGACAGTTCATCACGGTTACCTGGTTAAACACTTTTTTTTTTTTTTTAATTCTCCAGTGATCTAGGAAATTGTTTCATTTTTAACACAGGCTTATTTCTGATGGGGATGGGGGCATAGAATAATATGCCTAATAAGCTAAACGTTCTTAACGTTTCATGTCTTAAACTGTCTTTTTGAACATTGAGACCACCTCAAGTGCTGTAAAAATAAGAATGTTATATTAGGGGTGTGTGAGACGCCCTAGTCTAAAATCTATCTTTAAATATATTTCCTTTGTAATTTTCAAAGACTTCAGTAATTGTGTGTTATGGTGGAAATAATACTTTCCATTGGTCCACATTGCTCTGGACCAAACCTGGAGCATTTCTATAATTAGAGCTATCTATGAATCATTAAAAATGGATCTAGAATAATTTTGGGGAGAGGGAGTGTATCATTTAGTTTAGGCTTACCTCAGCAGCACTTCATAGGGTGAGGAGTTGTTTGTTTCTTTAAAGGTATAACTGCATTGTAAAATGACTGGGTTTATTGTAACAGTAATTTATGGGGGCACCCTTTTTGGATTCTCCATTGCCTCAGTTTCCTCAAGGAAAAAGTTACAGAGATTAAGCTAAATTTTGAATTTAGAGAATAACTGCTGTGTAATTTTGGTATaattaccataaatttagtgtcttaaaacacaacatacattatttcacaatttctgtaggtcaagagtgtagttaggttttctgctcagggtctcacaaggctgcaataaaggtgtcagccagagctgcagtcttatctgaagctagggggtcctcttttatgcacatatggcaaaatccattgcctagcaactgaagaaATCATGGGAActtcttcaaggccagcaagagaatctctgatctcagggaaggccttaagcgcttttttaaaggtctcacctgattagatcaggccacctacccaccagggtgatctcccttttgattaacccaaagccaaactgatgaggtaccttcattacccctgcaaaatcccttcacctttgccctgcattgtagtccaatcacaggggtgatacgcatcatattcaaagatcctgttcacagtcaagggagggggttatatggagtatgtataccagggaatcttgggagccatcttaagagttcttcctatgacaAGGACTCAACTATTTAGAACTGGAACAATTTACAAGTGATAGCCTTATATAGTTATCATAGCaagcttatttggggatcaaggttgcctctgagaacctaatgaaaactggaccagcttccccaaaaagtgtatataCATGGTAGTTTTTCATACAGTTTTAGGGGATTCATAAGAGTCCATGAATTACAGTCTGTCCCAACCCTTCCCTTTAGATGATGAGTTGTtgaggtgacttgcccaaggtcacacagctactaagggccaaataaagcccacatctcaactcccatactgcccagggcttctaattactaTTCTAAAGGTAATCTAAATTCATTTAAATTTGTGAACCAATGCAAAAAAATGTGAATGTAGCTTTTTGGATATTTTTTTTGTTTACTAAGGAATGGGTAACATTGTTATAGAAGCTTGCCTAAGAGTTTTGAAATTAGTTGACCTTTTTGAGTTTCCAAAATTGAATCTTCCATTGTAGCTATTAAAGTGAACTATAAATAGGCCAACTTTAATTGTTAACTCCTCGGGTTTGGTGGATTATCTACCATTTATATATAAAATTTCAGTTAGAATCCACCATTGGCGTTTTGAAGGCCAAGATAGCTGAGTATCTTATCCTTTTTGTAACTTCTTGATTATTTTACTTATTGGCAAAATTCATTAACTGTCAGCCAATAATTTAATATTATGGGAGGAAAAAATTTTGCCCAGATATCTGAGGCAATACTCCCAAACACTAACAAACTGATGCCTAACAAACTTGACATTTTGAACACTTAAAGTTTTCCCTAAACTTTTTAATAAGCACATTAATAAAGTATGCTTTTAAATATATATGTACAATAATTTTTAAAAGTTGCTGCAAGATGCCTTCAAATCAATATGCACGTTGGTGGCATTAGTGCAGTCTTCTAtttttatttttttgagacacagtctcgctctgtggcccaggctggagtgtagtggcgcaatctcggctcactgcaacctctgcctcaagggttcaagcaattctgcctcagcctcctgagtagctgggattacaggagtacgctaccacgcctggctaatttttgtatttttagtagaaatggggtttcaccgtattggccaggctggtattggaatcctgaccgcaaatgatctgcccacctcggcttcccaaagtgctgggattacaggcgtgagccactgcgcccaaccAGCCTTAATTCTTAATAAAGGAAGTTGAAAAATAATGAACATTGGTAAAACTATTCTAGTGTGATCAGAAGCAAATTTGGACTGTAGTGTCAAATTGATAAAAAACTAAGCACACCAATCATGTATAAGAAAAGTAGATTTAACATTTTTTTCCCTAAACACTTAACCCAGAAGTTAACAATAATCTTGAAAATTCCTTTTAAATCCAGGCCCTTTAGGTGATGGCAGTTTGACTCAGGATGTCCAAGTCCAGTGTATTTTCAATAAAATTGACTTGACAGCTACTGCTCTGGGTGTAAGAGCAGTTGACTGTGAGGAAAAGTAAATGGTTCTACAGATTCTTTATGATCTACCTCCCACCAGAGGACTGCAGTACTCCCTTGTTATTTATATTTTCTGCCCCAATTTTTGCCTTCTCCACAAATTTTATACCTTTTGTAGCTGCCTACTCCAGATTACTTCACCTTTCCAGACTATCAGTTCTTCCACTTTTATTCTTCATAAAGAAAATTCCAATAACCTGTTTCACTTAGGTTTTTCTATTACTCTTCAAGCATGAATCCTAATTTCCCTGACTATATCTTACCTCTGATCTCCATAACTGATGGATTCCTATCCTAGACTATGTTACTCTAATATTACCCAAGATTTTCTCCAGCCTGTTTTTACTCTTACTTTGAAACAGCTGTTTAAAATGACTCGTAATCTGCTTAAATCTACATGCTTTTTGTGGTTCTCAATCCAGTTACCTACCTTCCAGATAATTCCCTCACTGTCCTGTCCTCTCCATTCCTCTGATGTTTAAGCCCTGTGAGCCACCTTTCCCCCATCCTTTGTGCATAGTTACCATTTTACTCTTTCTtgttgcccaggcaggaatgcagtggtgccatcttggctcactgcaacctccacctcctaggttcaagcgattctcctgcctcagcctcctgagtagctgggaccacaagcgtgcaccaccacgcccggctaatttttgtatttttagtagagatggggtttcaccacgttggccaggctggtctcgaactcctgacctcagatgatccaccctccttggcctcccaaagtgctgggattgcaggcgtgagccaccgcctggccACCATTTTACTCTTTTTAGGTACAGTAATCTAATATCCAAAGTCTTGGACTCAGCTAAAGAGGGTATTTACCTTaaaaaaaaaaaaaaaaaGACTCCATCTTTTGATTCATAATTGTGGTGGGGGCGGGGAATCAAGACAACCTTAGTCACTTTGGTATTACCATAATTCTTGTCTTTTCAGGGTTGTCCTGTTCAGCTGCATAAAACATCATGTATTCTAGGTATTTCCTACCTTCACTTACATTTTTACTTGCCGATGTGCTGCCTTCATAAATGGGTATATTCCGCCACACATCTAGTAAGCCCCCAATGCAGTACACAATGTGTATCACTGATAAAACTCGCACTTCTGCCATGTCAGTATTATATTCAGTTGAGTGGTCTTTAGCATAGTGGCAGTCCTAGTCATCCTAACCTTTTAGTTAAGGTAAAATTACATATGTTTATAGAACTCATATAGACAAGCTAGTTTTTAAAATCTTCCTTTTAACCAGTTTAGGATGATCTAGGATAGCTAAGTTACCTACATGGTGACTGTTCGGTCTAATTCAGAAACAGAAGTACTAAAAGAATACTAAAAAGTTTTTACCCATTATCTCTATCCCTGTTTTCTTTTTGCAATTCTCAGCTGCAGGGAGCAAGAAAATACACAGCAGATAGGAAATGTTTGTTTGCATCCTGGCTTTCTCAACCGCACTTTACGTCCTTGAATATTCTAGATATTTACTCCTTCAAGAAGTCAGGAGTATATCCAGGCCTACCTATCATCCTTGCCATCCCCATTAACCCTCATTTTTCAGTATGTGTTTTACATTTATGGTTATTTTTCAGTCTATAGTATCTGTTCACTCATTGCTCTATCACATCTGAgtttctccgtctttctttccactagattgtaagctccttaagggcaaggTCGGCATATAAGCAAAGTTCTGTAAACACCGTGAAGGTACCATGAGTTCTATGGGTACTCAATAAATGCTTGTGATAATGA

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