Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RAB1AP2
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:86169842-86171062  UCSC
Coordinates (T2T) chr6:87378663-87379883  UCSC
Coordinates (hg19) chr6:86879560-86880780  UCSC
Strand -
Parental Sequence NM_004161.5
Parental seq. overlap 972 bp
Parental seq. overlap (%) 38.9%
Genomic Region Intergenic
Retrocopy Summary RAB1AP2, located on chr6:86169842-86171062, is a retrocopy of the parental gene RAB1A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RAB1A
Full Name RAB1A, member RAS oncogene family
Also known as RAB1|YPT1
Coordinate chr2:65086854-65130132
Strand -
Gene summary This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RAB1AP2
Bonobo Pan paniscus RAB1AP2
Gorilla Gorilla gorilla RAB1AP2
Orangutan Pongo abelii RAB1AP2
Gibbon Nomascus leucogenys RAB1AP1
Green monkey Chlorocebus sabaeus RAB1AP2
Crab-eating macaque Macaca fascicularis RAB1AP1
Rhesus Macaca mulatta RAB1AP1
Baboon Papio anubis RAB1AP1
Golden snub-nosed monkey Rhinopithecus roxellana RAB1AP1
Marmoset Callithrix jacchus RAB1AP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RAB1AP2
GATGTTATGATTTGTTGCATACTACATACAAAACAACTAAAGATATGTTTAACAAATAATGTACTTACGCAGCTGCAATGACATTACCAGCAGAAATCTCTAATATGTTTAATTACTCAAGTTACTTCTTATTGGCAACTCTGGGGCTAGAAAGTCTTGCTTCCTTCTTAGGTTTGCAGGTGAAACATGTAATACATATACAGAAAACTACATCAGCACAATAAGTGGGAATTTCAAAATAAGAACTGTAATATTATATGGCAAAATAATCAAGCTTCAACTAGGGGACACAACAGGCCAGGAAAGATTTTCATCACCTCCAGTTATTACACAGGAGCCTAAGGCTGTATGATATGACAGATCAGGAGTCCTTCGATAATGTCAAATAGTGGTTGCAGGAAATTGATCACTAGGCCAGTGAAAATGTCAACAAATTGTTGGTAGGAAACAAATGTGATTGCCCACAAAGAAAGTAGACTACACAACAACAAAGGAATTTGCTGATTCCCTTGGAATTCCATTTTTGGAAACTGGTGCTAAGAACACAGCAAATGTAGAACAGACTTTCATGAAAATGGCATCTGAGATTAAAAAGCAAATGGGACTAGAGCAACAGCTGGTGATGCAGAGAAGTCTAATTTTAAAATTTAGACCACTTTGGTCAAGCAGTCAGGTGAAGGTTGATGCTAAAATTTGCTTCCATCCTTTTCTCACACAATAAATTTGCAATCTAAACCCAAATGAAAAAACAAAATTGCCTGAATTTTACTGTATGTAGCTGCACTATAACAGATTCTTACCATCTCCACAAACGTCAGAGGTTGCAAATAGTCAATACTGACATTTTTTTATTACCTTGACTCAAGATAGCTAATTTCAGTTTCAGAAAACTTTGAAACTTTTGTGTGCTGCTTTACAAAATACTGCATGTAATCCTTGCCACTTTCCTGGTACCAGATTACGTCCCATGATTTCTTTTGTAAAGTTAGAATATATATTTTTGATGTTTACATTGGCATGTTTAGATGTCAGGTTTAATCTTCTGAAGATGAAGTTCAGCCACTTTTGTATCAAACAGCAAAAGCAGTCTGTCACTTCCATGTATACAGCTGTTACATGTAAGATCTGATTTGCTAGTTCTTCCTTTa
>NM_004161.5
ATTTTGGGTGGAAGCGATAGCTGAGTGGCGGCGGCTGCTGATTGTGTTCTAGGGGACGGAGTAGGGGAAGACGTTTGCTCTCCCGGAACAGCCTATCTCATTCCTTTCTTTCGATTACCCGTGGCGCGGAGAGTCAGggcggcggctgcggcagcaagggcggcggtggcggcggcggcagctgcAGTGACATGTCCAGCATGAATCCCGAATATGATTATTTATTCAAGTTACTTCTGATTGGCGACTCAGGGGTTGGAAAGTCTTGCCTTCTTCTTAGGTTTGCAGATGATACATATACAGAAAGCTACATCAGCACAATTGGTGTGGATTTCAAAATAAGAACTATAGAGTTAGACGGGAAAACAATCAAGCTTCAAATATGGGACACAGCAGGCCAGGAAAGATTTCGAACAATCACCTCCAGTTATTACAGAGGAGCCCATGGCATCATAGTTGTGTATGATGTGACAGATCAGGAGTCCTTCAATAATGTTAAACAGTGGCTGCAGGAAATAGATCGTTATGCCAGTGAAAATGTCAACAAATTGTTGGTAGGGAACAAATGTGATCTGACCACAAAGAAAGTAGTAGACTACACAACAGCGAAGGAATTTGCTGATTCCCTTGGAATTCCGTTTTTGGAAACCAGTGCTAAGAATGCAACGAATGTAGAACAGTCTTTCATGACGATGGCAGCTGAGATTAAAAAGCGAATGGGTCCCGGAGCAACAGCTGGTGGTGCTGAGAAGTCCAATGTTAAAATTCAGAGCACTCCAGTCAAGCAGTCAGGTGGAGgttgctgctaaaatttgcctccatccttttctcacagcaatgaatttgcaatctgaacccaagtgaaaaaACAAAATTGCCTGAATTGTACTGTATGTAGCTGCACTACAACAGATTCTTACCGTCTCCACAAAGGTCAGAGATTGTAAATGGTCAATACTGACTTTTTTTTTATTCCCTTGACTCAAGACAGCTAACTTCATTTTCAGAACTGTTTTAAACCTTTGTGTGCTGGTTTATAAAATAATGTGTGTAATCCTTGTTGCTTTCCTGATACCAGACTGTTTCCCGTGGTTGGTTAGAATATATTTTGTTTTGATGTTTATATTGGCATGTTTAGATGTCAGGTTTAGTCTTCTGAAGATGAAGTTCAGCCATTTTGTATCAAACAGCACAAGCAGTGTCTGTCACTTTCCATGCATAAAGTTTAGTGAGATGTTATATGTAAGATCTGATTTGCTAGTTCTTCCTTGTAGAGTTATAAATGGAAAGATTACACTATCTGATTAATAGTTTCTTCATACTCTGCATATAATTTGTGGCTGCAGAATATTGTAATTTGTTGCACACTATGTAACAAAACAACTGAAGATATGTTTAATAAATATTGTACTTATTGGAAGTAATATCAAACTGTATGGTGATAAGTATTGTTTTGATTCTTATGGTTAAAGGGAAATAGAGCCTTGCATTATATTCAACACAGCCATTTGTGTGTGCACAATGCAAACTAAGGTATTCTAGACCTATCTTAGAGCAGCATCCAGTATTTGCTTTCTAGATAATATGCCCAATAACATGACCTAGAGGGGCTTCTGTGCTGTGTAGGGATTTAACCAACTTCAGTGGTTCAGGGAGCTCAAACTATATGTAAAACAAGTTTAGAATGTATGCTATCTAGCCCGTTATCTCTGATCCTTCTCTAAAACCATTTGAAATAGCTTCATTGATCAACATTTCATAAATGCATCTGTGGTAGAGGTAGAAAGCAGCACCTTTCCTAATTGGCAAATGATCAGACTAATGTGTGCTAATGTTTTTCTTCCATGCTTTCAGTCAGATTCAACTATTTTATCCTCCACAGTTGCTTAACTTGGTGTTGGAGGAGGGTTTAAGCATTAAGATAGGAAGCAGGAAATTTGATTGCTCTAAATTTAGAAATTATATCCCTAAAAATTAAAACATGAATACTGGGTGGTAATGATAATTGAGGCAAATGTATTTATTTTGGTGACATTTTGCATATATGAAGATTTTCTGAAATAGGACCTTCAAGATCCTAGGGGGTTTTGTTTGGTTTTTAATTGTGAGGAATAAAAAATCTTCTGCCCACACTGGCATTTTAAGGTGACTGAGGTCAAACGTTGTTTCCTTAGGTTGAAATAGCAGCCAAAACATTCTTCACGCAGGGGCTTGGGATATGGCTGCTGGCAACACATTTTGTTGTGGGCTCCTTAATTTAATGATAAAATTTAAGCTAAACACAAGCCAAAAATGAATAGGTTTTTTTAATTTTTATTTTTCACTAAACAGGCAATTGAAATACATGGTACAAAAATAAGTGGTAAGATAATTGTAAAATGAAATGGACAGAATATTCAATTTTCCATCTATGAAAATTTCACAATAAAAATCATAGTTTACTTTGTA

Publications

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