Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DIAPH2P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:99082445-99082855  UCSC
Coordinates (T2T) chr6:100256798-100257208  UCSC
Coordinates (hg19) chr6:99530321-99530731  UCSC
Strand +
Parental Sequence NM_007309.4
Parental seq. overlap 380 bp
Parental seq. overlap (%) 10.6%
Genomic Region Intergenic
Retrocopy Summary DIAPH2P1, located on chr6:99082445-99082855, is a retrocopy of the parental gene DIAPH2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DIAPH2
Full Name diaphanous related formin 2
Also known as DIA|DIA2|DRF2|POF|POF2|POF2A
Coordinate chrX:96684842-97604997
Strand +
Gene summary The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DIAPH2P1
Bonobo Pan paniscus DIAPH2P1
Gorilla Gorilla gorilla LOC109024764P2
Orangutan Pongo abelii DIAPH2P1
Gibbon Nomascus leucogenys DIAPH2P1
Green monkey Chlorocebus sabaeus DIAPH2P1
Crab-eating macaque Macaca fascicularis DIAPH2P1
Rhesus Macaca mulatta DIAPH2P1
Baboon Papio anubis DIAPH2P1
Golden snub-nosed monkey Rhinopithecus roxellana DIAPH2P1
Marmoset Callithrix jacchus DIAPH2P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DIAPH2P1
CTTGGTGATCTCAGTAACTTCTGAACTTTGTTTTTAGAAGCAGTGAAAGAAAACAGTAAGAGAAGAGAAATGGAAGAGAAGACTAGGAAGGCAAAGCTTGGAAAAGAGAAAGCCGAACAAGAAAAGTTAGAATACCAGAAGAAAAAGAAACAATTCATTGATATAAACAGAGGGGGTGATGAGACTGGTCTGATGGATAATCTTCTAGAAGCCCTACAATCAGTTGCAGAATTCTGAGACTGACGAAAGTGGATTCCAAGGAATCCAGTGGTAAATCAACCCTGTGCAACAAGGGCTAATCCAAGATCATCTACATAACCAGCCTGAGTGCTGTTTTAAACAGGATTGGGTGATTGTACAACATGACTTTTTAAGATAATCAAGCAGCAAAAGTTTCTAGTGGAAACATGA
>NM_007309.4
GCCCCAGCGCCGAGTAGTGGCAACGGCGTGGTTGCGTCGGGGGTGCCTGGGAGCCTGGAGTCCCGGGGGCCTGAAATCGGCAGCTTCCCGGGCAGACACTCTCTCCCTCAGGAAGAGGTGCCGCCGAGTCAGCGCGGGGCAGTGTGAGCGCCCCGAGGTGCTTTCTCAGTTGAGGAGAGGTGGGGTTACAGGGCACAGGTGACAGGGCCGGAGAAAGATGGAGCAGCCcggggcggcggcgtcgggagcgggaggcggcagcgAGGAACCCGGTGGGGGCCGGAGCAACAAGCGGAGCGCGGGGAACCGGGCCGCCAATGAAGAGGAAACGAAAAACAAACCCAAATTGAACATTCAAATAAAAACTTTGGCAGATGATGTGCGTGACCGAATTACAAGTTTTAGAAAATCTACTGTCAAAAAAGAAAAACCTCTTATTCAACATCCTATTGATTCTCAAGTCGCGATGAGTGAGTTTCCTGCAGCTCAGCCATTATATGATGAACGATCTTTGAATTTGTCAGAAAAGGAAGTATTGGATCTCTTTGAAAAAATGATGGAGGACATGAACCTTAACGAAGAGAAAAAAGCTCCTTTACGAAACAAAGACTTTACCACCAAACGTGAGATGGTTGTCCAGTATATTTCTGCCACTGCCAAATCTGGTGGGCTGAAAAACAGCAAACATGAATGCACCCTGTCTTCACAAGAATATGTTCATGAATTACGATCGGGTATATCAGATGAGAAACTTCTTAATTGCCTAGAATCCCTCAGGGTTTCTTTAACCAGCAATCCGGTCAGCTGGGTTAACAACTTTGGCCATGAAGGTCTTGGACTCTTATTGGATGAGCTGGAAAAGCTTCTGGACAAAAAACAGCAAGAAAATATTGACAAGAAGAATCAGTATAAACTTATTCAATGCCTCAAAGCATTTATGAATAATAAGTTTGGATTACAAAGGATTCTAGGAGATGAAAGAAGTCTTTTACTATTGGCAAGAGCAATTGACCCCAAACAACCCAACATGATGACTGAAATAGTAAAAATACTTTCTGCTATTTGCATTGTTGGAGAAGAGAACATTCTAGATAAACTTTTAGGGGCTATAACAACAGCAGCAGAAAGAAATAACAGGGAACGATTTTCACCAATTGTGGAAGGTTTAGAAAATCAGGAAGCCTTGCAATTACAGGTGGCCTGCATGCAGTTTATAAATGCCCTTGTCACTTCTCCTTATGAGCTTGATTTTCGAATACATTTAAGGAATGAATTCCTCCGTTCAGGACTAAAAACAATGTTACCAGATCTAAAAGAAAAAGAGAATGATGAGCTTGATATTCAGTTGAAAGTATTTGATGAAAACAAAGAAGATGACCTAACTGAATTATCACACCGTCTCAATGACATTCGAGCAGAAATGGATGATATGAATGAAGTCTACCATCTTCTATATAATATGCTGAAGGACACTGCTGCTGAAAATTACTTCTTATCTATTCTACAACATTTTTTGCTTATCAGAAATGATTATTATATCAGGCCACAATATTATAAAATAATTGAGGAATGTGTTTCACAGATAGTGCTACACTGCAGTGGTATGGATCCAGACTTCAAATACAGGCAAAGATTAGACATCGATTTAACTCATCTGATAGATTCTTGTGTGAACAAGGCGAAAGTTGAAGAAAGTGAACAAAAAGCTGCAGAGTTTTCAAAGAAGTTCGATGAAGAATTCACAGCTCGACAGGAAGCTCAAGCAGAGCTTCAAAAAAGAGATGAGAAAATCAAAGAACTTGAAGCAGAAATCCAGCAACTTCGAACCCAGGCACAAGTACTCTCAAGTTCATCAGGAATTCCAGGTCCTCCTGCAGCACCTCCATTGCCAGGTGTAGGGCCGCCTCCACCACCACCCGCGCCACCTCTACCCGGAGGAGctcctcttcctcctccaccacctcctTTACCTGGAATGATGGGGATaccaccaccacccccaccaccacTTTTATTTGGGGGACCTCCTCCACCACCACCCCTTGGAGGAGTTCCTCCTCCCCCAGGAATATCACTTAATCTACCTTATGGAATGAAGCAGAAAAAAATGTATAAACCTGAAGTGTCCATGAAGAGAATCAATTGGTCAAAGATTGAACCCACAGAATTATCTGAGAACTGTTTCTGGTTAAGAGTCAAAGAAGACAAGTTTGAGAATCCAGATCTCTTTGCCAAATTGGCATTGAATTTTGCTACTCAGATAAAAGTTCAAAAGAACGCAGAAGCATTAGAAGAAAAGAAGACTGGGCCTACAAAGAAGAAAGTGAAAGAACTGAGAATTTTGGATCCCAAAACAGCTCAGAATCTGTCCATCTTTCTGGGATCATATCGCATGCCATATGAAGACATAAGAAACGTTATTCTGGAGGTTAATGAAGACATGCTGAGTGAGGCTTTAATTCAGAACCTTGTGAAACATCTTCCTGAGCAGAAGATACTCAACGAATTAGCAGAGCTTAAGAATGAATATGATGACCTCTGTGAGCCTGAACAATTTGGAGTTGTGATGAGCTCTGTGAAAATGTTACAGCCTCGTCTCAGTAGTATCCTGTTCAAGCTCACATTTGAAGAACACATAAACAACATCAAACCAAGCATCATAGCAGTAACTCTTGCCTGTGAAGAACTGAAGAAAAGTGAAAGCTTTAACAGACTTTTAGAGTTAGTTCTTCTTGTTGGAAACTACATGAACTCAGGCTCAAGAAATGCCCAGTCTTTGGGATTTAAGATCAACTTCCTTTGTAAGATCAGAGATACTAAATCAGCGGATCAAAAAACAACCCTTTTGCATTTTATTGCCGACATTTGTGAGGAAAAATATCGAGATATCCTAAAATTTCCTGAAGAACTGGAACACGTAGAAAGTGCAAGCAAAGTTTCAGCTCAAATTCTCAAGAGCAACCTTGCATCAATGGAACAACAAATTGTTCATCTGGAACGTGACATCAAGAAATTCCCCCAAGCAGAAAATCAACACGATAAGTTTGTGGAAAAGATGACCAGCTTTACAAAGACTGCCCGAGAACAGTATGAAAAACTCTCCACCATGCACAACAACATGATGAAGCTCTATGAGAATCTTGGAGAATACTTCATTTTTGACTCAAAGACAGTGAGCATAGAAGAGTTCTTTGGTGATCTCAACAACTTCCGAACTTTGTTTTTGGAAGCAGTGAGAGAAAACAATAAGAGAAGAGAAATGGAAGAGAAGACCAGGAGGGCAAAACTTGCAAAAGAGAAAGCTGAACAAGAAAAGTTAGAACGCCAGAAGAAAAAGAAACAACTCATTGATATAAACAAAGAGGGTGATGAGACTGGTGTGATGGATAATCTTCTAGAAGCCCTACAATCAGGTGCAGCATTCAGAGACCGTCGAAAGCGGATTCCAAGGAATCCAGTGGTAAATCATCCCTGTGCAACAAGGGCTAATCCAAGATCAGCTACATAAACGGCCTGAGTGCTGTTTTAAACAGGATTGGGTGATGGTACAACATGACTTTTTAAGATAATCAAGTAGTAAAAGTTTCTAGTGGAAACATGA

Publications

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