Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name EIF3IP2
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:118950366-118951258  UCSC
Coordinates (T2T) chr7:120265738-120266630  UCSC
Coordinates (hg19) chr7:118590420-118591312  UCSC
Strand -
Parental Sequence XM_024450518.1
Parental seq. overlap 529 bp
Parental seq. overlap (%) 34%
Genomic Region Intergenic
Retrocopy Summary EIF3IP2, located on chr7:118950366-118951258, is a retrocopy of the parental gene EIF3I. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name EIF3I
Full Name eukaryotic translation initiation factor 3 subunit I
Also known as EIF3S2|PRO2242|TRIP-1|TRIP1|eIF3-beta|eIF3-p36
Coordinate chr1:32221584-32231604
Strand +
Gene summary Contributes to translation initiation factor activity. Involved in translational initiation. Located in extracellular exosome. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes EIF3IP2
Bonobo Pan paniscus EIF3IP2
Gorilla Gorilla gorilla EIF3IP2
Orangutan Pongo abelii EIF3IP1
Gibbon Nomascus leucogenys EIF3IP2
Green monkey Chlorocebus sabaeus EIF3IP2
Rhesus Macaca mulatta EIF3IP2
Baboon Papio anubis EIF3IP1
Golden snub-nosed monkey Rhinopithecus roxellana EIF3IP1
Crab-eating macaque Macaca fascicularis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>EIF3IP2
ATCGTCAATGTGTGGTACTCTGTGAACGGTGAGAGGCTGGGCACCCACGTGGACCATACAGCAGCTGTGTGCTGCATGGACAGTGACTGGGACACCAAGCATGTCCTCCCTGGCTCAGCTGACAACAGCTGTCGTCTCTGGGACAGGGAAGCAGTTGGCCCTACTCAAAACTGATTTAGCTGTCCAGACCTGTGGCAAGGACTTTGGGAACAATATCACTATATTCTCTACAGACAAGTAGATGGGCTACCAGTGCTTTGTGAGCTTCTTTTATCTGCAGGACCTAAGGCAGATTGACAGCAATGAGACATACATGAAAATCCTTTACAATGACTATAATATCACTAGTGCTTTTTGAGGACCCCCCAGGGGAGTGCATCATCACAGACCATAAGAGTGGAGTGTCCAACCAGTATAATGCCACATCTGGAGAGGTATTGGTGAGTGTTAAATAGCACTCCCAGAAGATCAGTAACATCAAGTTATCCAAGGACATAATCATGTTTGTCACTGCAACCAAGGACAACACAGCCAAGTTCTTTGATTCTACAACTCTTGAACATCAAGAGACTTTCTGGACAGAACATCTCATCAACTCAGACGCCCTTTCCCCAGTTATAATGACCATGTGATACTGGGTGACAGAGAGAAAGCCATGGATGTAACCACAACCTCCAACAGGACTGGCAGGTTTGAGCCCAGGTTCTTCCATTTGGCCTTTGAAAAATAGTTTGGAAGAGTCAAGAGTTACTTCACAACTGTCAACAGGGTTGCCTTCCCTTCAAATGGCAAGAGTTACAGCAGCGGCGGTGAAGATGGTTATGTCCATATTCACTGTTTAGGCCCACAGTACTTGGAATTTGAGCTTGAGGATTAAGAAGCTGGATCTCCTC
>XM_024450518.1
CGGCGGAGGCCCGCTTCAGCAGCGGCTGCGTGCCACCCCACAGAGCGGCCACCAGCACCAGAGCCAACACCTGCCCTGAATGCAGACGAGGGCGGAGACCCATAATCCGGAAGTGACCTCGAAACCTTTTCCGGTCTTACTCACGTTGCGGCCTTCCTCGCGTCACAGCCGGGATGAAGCCGATCCTACTGCAGGGCCATGAGCGGTCCATTACGCAGATTAAGTATAACCGCGAAGGAGACCTCCTCTTTACTGTGGCCAAGGACCCTATCGTCAATGTATGGTACTCTGTGAATGGTGAGAGGCTGGGCACCTACATGGGCCATACCGGAGCTGTGTGGTGTGTGGACGCTGACTGGGACACCAAGCATGTCCTCACTGGCTCAGCTGACAACAGCTGTCGTCTCTGGGACTGTGAAACAGTCTGGAGAGGTGTTGGTGAATGTTAAGGAGCACTCCCGGCAGATCAACGACATCCAGTTATCCAGGGACATGACCATGTTTGTGACCGCGTCCAAGGACAACACAGCCAAGCTTTTTGACTCCACAACTCTTGAACATCAGAAGACTTTCCGGACAGAACGTCCTGTCAACTCAGCTGCCCTCTCCCCCAACTATGACCATGTGGTCCTGGGCGGTGGTCAGGAAGCCATGGATGTAACCACAACCTCCACCAGGATTGGCAAGTTTGAGGCCAGGTTCTTCCATTTGGCCTTTGAAGAAGAGTTTGGAAGAGTCAAGGGTCACTTTGGACCTATCAACAGTGTTGCCTTCCATCCTGATGGCAAGAGCTACAGCAGCGGCGGCGAAGATGGTTACGTCCGTATCCATTACTTCGACCCACAGTACTTCGAATTTGAGTTTGAGGCTTAAGAAGCTGGATCTCCTgccgggcgtggtggctcatgcctgtaatcccaccactttttttttaaggcaggcggatcacctgaggtcaggagtttaagaccagcctgaccaacatggagaaacctcgtctctactaaaaatacaaaaattagccaggcatggtggcacacgcctatagtcccagctactcaggaggctgaggcaggagaatcacttgaacccaggaggcagaggttgcagtgagctgagatcacgtcattgcactccatcctgagccacaagagcaaaactccgtctcaaaaaaaaaaaagaagaaGGTGGATCTCCAACCAGGCCAGAGAAGATTCTCACAGAAGGTTTTGAACTCTAAGAAATAAATTGGTTTGGTAATAAATGGCTTCTGGTCAGATA

Publications

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