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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CMTM7P1
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:121419072-121419266  UCSC
Coordinates (T2T) chr7:122734362-122734556  UCSC
Coordinates (hg19) chr7:121059126-121059320  UCSC
Strand +
Parental Sequence NM_138410.4
Parental seq. overlap 170 bp
Parental seq. overlap (%) 9.2%
Genomic Region Intergenic
Retrocopy Summary CMTM7P1, located on chr7:121419072-121419266, is a retrocopy of the parental gene CMTM7. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CMTM7
Full Name CKLF like MARVEL transmembrane domain containing 7
Also known as CKLFSF7
Coordinate chr3:32391825-32455528
Strand +
Gene summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CMTM7P1
Bonobo Pan paniscus CMTM7P1
Gorilla Gorilla gorilla CMTM7P1
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CMTM7P1
AGGTCATCCTGTTGATTGCCTTCATCTGTGTTCAGAGCTCTCTGTAGACTGACTACAGCACTTACAGCTACTTTGAAGTGGTCACCATTTTCAACTTGATAATGATCCTCACCATTTTTTCTGATCCACCTCTTCTGCCTGCTCACCTGTATCTGTTGGCCCTTGTCAGAACTTCTGCACTATTTAATCAGTACC
>NM_138410.4
ATCTGGCCCCTGGGCAGCTGCCCGGGGAGGCGGCCAGCGAGCTGGGGCCGCGCAATGTCGCACGGAGCCGGGCTCGTCCGCACCACGTGCAGCAGCGGCAGCGCgctcggacccggggccggcgcggcccagcccagcgcgagcccCTTGGAGGGGCTGCTGGACCTCAGCTACCCCCGCACCCACGCGGCCCTGCTGAAAGTGGCGCAAATGGTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTCCCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGCGACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCTCTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGGAACTTCTGCACTATTTAATCGGTACCCTGCTCCTCCTCATCGCCTCCATTGTGGCAGCTTCCAAGAGTTACAACCAGAGCGGACTGGTAGCCGGAGCGATCTTTGGTTTCATGGCCACCTTCCTCTGCATGGCAAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGATGAGGCCACAACCCCTAGGCCCCTCAGGAGCTTTGCAGAGAGGAGGACGTGTACTCCAGGCGAGGCCTCTGGACCTGTGTTCCTGTGCCAAAGTCCTGTCAGGCTGGTGGGCACCAGGAAAGGCCTGCACCCTCTTCCTGCTCTCCCAGGAAGCCAGCTCCCTGAGCTCCTGAGCCAGCCGGAAACTCTTCCTCCAGCCTTCCGGGGAGAACATCCCTCCCATTCTGGGAAAGGAAAGCAGCCTCCAGGGAAATGTTTTCTGCCTTCCTGCTTCTAGAACCACCTCAGGTACTGATGAACCCCACTTAGCACAGCTGAAGGGGTTTGTGAATACTCCCGCCTAAATCCCTTCTACTTCACTCCTCAGGGGAGTGAAGTGCCTTAAGAAACAAAGCCCTGTCCTAATTTATCTAGCTTGTCAGTCCGGTCTTAGAGATACCCTCTTTCCTGAAGTGAGGCGTGCCTGTAGAAACACTATGTGGTCAGCCTGTCCCCAAGGAGATCTTGTGTCTCCTCTCCATCTCTGCCTTTGTTACCAGTGTGCATGTGTTTGTGTGTTTTTTAATAAAATATTGACTCGGCCAGTTGCACAAGGATTTCTTATTGAACCAGATGAAGGCTGTAAAACCTGGCCTGAAACAGTTTCCATTCGAGCTTGTGTCTGGCCCATGGCCCTCCACCCGTGCTCTGTGTGTGCCCCTTGCTGAACTGCTGGACTTCAGGTTTTCTCTCCATCTTGGGGGATAGTATAGCAGGGCAGAGTTTTAGGTAAACATGTGCAGGTTCTCAATTATATTCACGTCCTCCTTCTCCTGCAATACCAATCTTCTCATTTTGGAAAGAGCTTTAGAGCAAGCTAAGGGTTGTGTTTACACTATGATGATTAATGATCTCGGCCTAAATGTGCTGTTTCGCTGATCTTGAGCTGCTCAGTTGGCTAGAAAAAGGAGGGATGGAACAATGTTTGAGCAACCCCGTGTGCAAGGACCTACATTCACAACCACATCTAATAGCGATGGTAGTGACTGCAAGGGGGCAGGTTATAGGACCACATTTTTAGAAATGAAATCGGGGCTCCATccccaggcacagggcaagccagtgaggagctgggctcaggatctaggtctgcctgactcccagccccatccttgcctctgctgagTGTTGCCGGAAATGGAAGCAGCCCCTGTGGGCTTTGAGCTGGAGCTCTGGGGCTACTCTTGTGGCTGCTGGCCAGCTCGGGGCATCGGGTTCTGTCTGGGATGATCTAA

Publications

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