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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CENPSP1
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Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:12685814-12686316  UCSC
Coordinates (T2T) chr7:12816887-12817389  UCSC
Coordinates (hg19) chr7:12725439-12725941  UCSC
Strand +
Parental Sequence NM_199294.3
Parental seq. overlap 439 bp
Parental seq. overlap (%) 48.2%
Genomic Region Intergenic
Retrocopy Summary CENPSP1, located on chr7:12685814-12686316, is a retrocopy of the parental gene CENPS-CORT. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CENPS-CORT
Full Name CENPS-CORT readthrough
Also known as APITD1|APITD1-CORT|CENP-S|CENPS|FAAP16|MHF1
Coordinate chr1:10430433-10452153
Strand +
Gene summary This locus represents naturally occurring read-through transcription between the neighboring APITD1 (apoptosis-inducing, TAF9-like domain 1) and CORT (cortistatin) genes. Alternative splicing results in multiple transcript variants, two of which encode fusion proteins that share sequence identity with the products of each individual gene. [provided by RefSeq, Aug 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CENPSP1
Bonobo Pan paniscus CENPSP1
Gorilla Gorilla gorilla LOC101154356P1
Orangutan Pongo abelii APITD1P1
Gibbon Nomascus leucogenys CENPSP1
Green monkey Chlorocebus sabaeus LOC103225627P1
Crab-eating macaque Macaca fascicularis LOC102136402P1
Rhesus Macaca mulatta LOC107000378P1
Baboon Papio anubis CENPSP2
Golden snub-nosed monkey Rhinopithecus roxellana CENPSP1
Marmoset Callithrix jacchus APITD1P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.20.40.60.8
log10(TPM+1)

Related Sequence

>CENPSP1
AGAAATGTGTGCAAGACATGCGAAAACCACCACCATTAACACTGAAGATGTGAAGCTCTTAGCCAGAAGGAGTAATTCACCGCTAAAATACATTCAGACAAAAGTGAAGAGCTTGCGCAGATTAACCTAGAACGAAAGGCACAGAAGACAAAGAAGAGGATGGAAACAAAAATGCAAGGGAGCCAGCAGAGGCTGGAGTACAGGAAAGTTAAGAATTAAACTCTCCCGCTGCTTGGAAAATGCAGCTTTCTGCAGGTAGAGCCACCTAGTATGTATATGGCCACAAAGGGAATTTTGAAGGGATAAATAGAGATTAAAAAAAAAAAAAAGGCTAGATGGCTTTTTGTGTTGTATTTTCCAAGTCGTTAACTGCAAACGCTAGTTTTAAAGAGAACTGGACACTCAATCAAAATACTCCTGTCTCACTCCAGCACATACAAATGGTGTAGTTGAATGGTATATTGGAAATTATATCTATTGCAATTAAAATTGTGTGAGCAATT
>NM_199294.3
GCGCCGCGGCGGGAAAATCCGACCTGGCCGCGCACCACCGCCCCTTCTCGGCCCTCCTGCGTTTGCCCAGGGTCGGCCCGCAGTGATGGAGGAGGAGGCGGAGACCGAGGAGCAGCAGCGATTCTCTTACCAACAGAGGCTAAAGGCAGCAGTTCACTATACTGTGGGTTGTCTTTGCGAGGAAGTTGCATTGGACAAAGAGATGCAGTTCAGCAAACAGACCATTGCGGCCATTTCGGAGCTGACTTTCCGACAGTGTGAAAATTTTGCCAAAGACCTTGAAATGTTTGCAAGACATGCGAAAAGAACCACAATTAACACTGAAGATGTGAAGCTCTTAGCCAGGAGGAGTAATTCACTGCTAAAATACATCACAGACAAAAGTGAAGAGATTGCTCAGATTAACCTAGAACGAAAAGCACAGAAGAAAAAGAAGTCAGAGGATGGAAGCAAAAATTCAAGGCAGCCAGCAGAGGCTGGAGTGGTGGAAAGTGAGAATTAAAGTCCCTCGCCGCTTGGAAAGTGCAGCCTTCTACAGGTAGAGCCACCTAGAAATGCATATGGCTGCAAAGGAAACTTTGAAGGGTTAAATAGAGATTTAAAAAAATAAAATAAAAAGGCTGGGCTAGGGTGCTTTTTGTGCTGAATTCTCCACATTGTTAACTGCCAAAGCTAGTTTTAGAGAATGAGAAAGTCTTAAGCAAAATACTCCCAGGTCTCACTCCAGAACATAAAAATGGTGTGTGATCAAATGGTATATATTAGAAATTACATCTGTTGTAATTAAAATTGTGTGAGCAATTAAACATGGTTGACTTTTTCAAGCAAAAATCAGTTCATCTTTTGATGTAATTTTCTAGGCTAAATGGCAATCTCTGAAAGATGAATAAAGCTATATTTATTTA

Publications

PMID - Link Title
No publications available for this retrocopy