Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name EMG1P1
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Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:128668828-128669170  UCSC
Coordinates (hg19) chr7:128308882-128309224  UCSC
Strand -
Parental Sequence NM_006331.8
Parental seq. overlap 295 bp
Parental seq. overlap (%) 6%
Genomic Region Intergenic
Retrocopy Summary EMG1P1, located on chr7:128668828-128669170, is a retrocopy of the parental gene EMG1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name EMG1
Full Name EMG1 N1-specific pseudouridine methyltransferase
Also known as C2F|Grcc2f|NEP1
Coordinate chr12:6970913-6979936
Strand +
Gene summary This gene encodes an essential, conserved eukaryotic protein that methylates pseudouridine in 18S rRNA. The related protein in yeast is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes EMG1P2
Bonobo Pan paniscus EMG1P2
Gorilla Gorilla gorilla EMG1P2
Orangutan Pongo abelii EMG1P2
Golden snub-nosed monkey Rhinopithecus roxellana EMG1P2
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>EMG1P1
GAGCTGGTGTTCAACAGTGACCCTATTGTTTTTGTGGTGGGGGCCTTTGCCTAGAGCAAGGTCAGTGTGGAATATACAGAGAAGGATGGTGTCTAGCAGCAACTACCTCCTTTCTGCTGCCCTCATCTGTGCAAAACTTATCACAGCCTTTGAAGAAATGGTGGGGGGTGCCACTTGACAGTAATAGGACATTATTCTGAAGCCAGAAGCTGTAGACATCATGTCCCTTGAGGCTATTCTGAGCTGACTGCTGAAGATGACCTTCCTGCACTGAGATTGTAGGATTTGGGGAAACCAAGGCTGTATATTTGCTATTGTTTATCCCATACTGTTCTTGCAAACA
>NM_006331.8
ATTGTTGCAAGATGGCCGCGCCCAGTGATGGATTCAAGCCTCGTGAACGAAGCGGTGGGGAGCAGGCACAGGACTGGGATGCTCTGCCACCCAAGCGGCCCCGACTAGGGGCAGGAAACAAGATCGGAGGCCGTAGGCTTATTGTGGTGCTGGAAGGGGCCAGTCTGGAGACAGTCAAGGTAGGGAAGACATATGAGCTACTCAACTGTGACAAGCACAAGTCTATATTGTTGAAGAATGGACGGGACCCTGGGGAAGCGCGGCCAGATATCACCCACCAGAGTTTGCTGATGCTGATGGATAGTCCCCTGAACCGAGCTGGCTTGCTACAGGTTTATATCCATACACAGAAGAATGTTCTGATTGAAGTGAATCCCCAGACCCGAATTCCCAGAACCTTTGACCGCTTTTGTGGCCTCATGGTTCAACTTTTACACAAGCTCAGTGTTCGAGCAGCTGATGGCCCCCAGAAGCTTTTGAAGGTAATTAAGAATCCAGTATCAGATCACTTTCCAGTTGGATGTATGAAAGTTGGCACTTCTTTTTCCATCCCGGTTGTCAGTGATGTGCGTGAGCTGGTGCCCAGCAGTGATCCTATTGTTTTTGTGGTAGGGGCCTTTGCCCATGGCAAGGTCAGTGTGGAGTATACAGAGAAGATGGTGTCCATCAGTAACTACCCCCTTTCTGCTGCCCTCACCTGTGCAAAACTTACCACAGCCTTTGAGGAAGTATGGGGGGTCATTTGACAGTAGTAGAACCTGTTCTGAAACCAGAAACTGTTGATGTCACATCCTTTGACCCTGGTCTGAGCTGACTGCTGGAAGATGATCTTTCTGCACTGAGACTGTGGAGTTTGGGGAAGCCAAGGCTGTACATTTGCTATTTGTTTATCCTATGAATACTGTTCTTGCAAACCTGGTTGTTTTGGGGTTCCTAAAGTATCCAGTGGTGTAAAACTGTTTGTTCCCCGGGACTTCAGGGACAGATAGGAGGTTACAGAGTTTGCAGTTTGGTTCCATGCTTTGAAGGCAGGCTTTAGCTCCCAGATTCCCATGTGCTAAAGGAGAGAACCCTGATGATGGAGAAGAACTGTGAAAGAGAGCAGTCAGGAATGCTAGTGGTGAAAAACTGAACAAACAGAAGTGATTTTATCTAATACAGTTCCAAGGTAGAAAAAGTGGAGCAGGCAGGGCCTTGCACCCCTCTCCACCCCCCCATGGGGGGGGTGGTGGTAGCGGCACATACACAATCATAGTAAATTGGCAGAAGAAAAACACAATAGATTCCTGGCTAGATGGGGAGAGATAAGGCAATGTGCATGGGGGAATCAGAGGGGAGATGTGAGCCCCTCTGCTCCTCCCACAAGAGTTTCCCCTTTGggccgggcacggtggctcacgcctgtaatcccagcactttgggaggcggaggcgggtggatcacttgcggtcaggagttcgagaccagcctggccaacgtggtgaaatcccgtttctactgaaaatacaaaaattagctgggcatggtggcgtgcctgtattcccagctacttgggaggctgaggcaggaaaatcacttgaacccaggaggtggaggttgcggtgagctgagatcccgccactgcattccagcgtgggtgacaaagcaagacgccttctccaaaaaaaaGTTTCCCCTTTGGCCCCAAATGAAGACTTGGCTGGCAGCAGAGGCACAGCTGGAAGCATCGATCTTCCACCTCCCTGGCTTTTCCATTCTCTGCTCTGGGGCAAAGGAGTGCTGTGAAAAGGGAGACGAGTAGTTTCTGCACCAGTCCCGCACAGGCCACCTGCAAGACAAGAGGAGTTTGGAAGGCTGGTTAGTTACTCCTGTAATTCCTGGTCTATAGCCCTTCCAGATGTTTCCTAGCATGCCTCAATAAGTCACAGTAGTCATTGCCCATACTGTGTTCCTTAGTAGCCAGGCTAATCCTTGGAATTCACCCCAGATTTCTAATACTATTGTTTTTTTCCAGTCTGTTGCTCTATTCTGTAACCTGGTGGTAGTTTTAGTTTAGCTGTATTAACTTACCAGGGAAATGGATTATTCCATCTTCTTTAACTTCTCTTTCCTTGGCACCATTGCTTTGTGAATATAAGGCAATATGAATAGTAGGCTCAGGAAGAAGATGTGGCCAAGGAAATAGATGGATTTATACACCTGTGGAGAGAGAGGCCACTAAGGTAGACAGGCCTGGAGTGTCCTTTGCAACCTTTGAGGTTGCAGTGAGTCCCTCCCAGTCTCACAAGCAGGCCTTCACTTGCCTTAAGCCATTTGTCCCACGTGAAGAGGCAGAAGGCAGTCATGGAGTAACCCATGAAGAGCCAGTGGATGGTCTGTTGCACCAAATAGTAGAAGGGCTGGAGGACAGTAATGGCGGCCAGCTTGCTCAGGGTGGGGCTCTCTTGAATGAGCCTGGCAGCCTGGGGAGGGAGGAGGAGCTCATCAGCATCTTGTCCCTTATATTCCCCTTCACCCCCACCCTGGAGGCCTACCTGTCTTTCCACAATAACAATGAGGAATTCCATCTGGAAGCAGACCAGGTATCCTGAGTGCAGGCCGTGCCAGAGGGCCAGGAATAGCAACGAGAGACCCTGAGAGAGTTCTTTATTTCCAAGGAACTTGAGTCGTTTGAAGATGTAGCTGGAGAAAAGGGTGGGTGGGGCGACCCTCAAACTGACTGGTCCTTGCATCCCGCCACCTGCCTCTGGGTCCTCACCCTGAGGATTGGATTGGAGTGCTGGTGGGTTCCCACGTGTAGCCCCCAGAGGGTACAGGAGGCAGTGCTGACTGATTACTTTTAGAGATGGAAAGCAGACCCAAGGCGGAGCTGGAGACCGTGTGCGCACGAGCCACTTGGTTCAGCAGCAGTGACTGAGGCTgatgctgagatcagtggtgaaccagacactctactcaagctgcccacactctagtggtggggacaaacaagtaaagctgttgataaacagggcagtggaggacATAAGTCCATTGGCAGAGCTGGAGTAACACCCAGGTCTTAACGCACTTTTATATCTTGCCTTTTTTTCAAATATGACAGTAATGGTTTTTTTGGGAGGGGGGTATAGGTGGGGGTCAAAGTCAGTGTGAGCGACAGGGGGTTCTGCCCAGATGGGAAAGACGCATAGGGGTGACATGGTACACCCCTGCCCTCCAATCTGGGAAGACAGTGGAAGGAAGGAACCAGGGTCCAGGCTCCCCACCAGCAGCTCACCGGGCCACCCAGGCGTTGGTGTTGATGTTGAATGAGGCAATGGTGCCAGTGAAGCGGGGGTTTGTTTCAAAGAGCCACACCTTCATGTTGGCACAGGCATCCCACTTTGCCTTGCCCTTTTCTTCAAAGCCATTGAAGCCCAGGCCCGTCAAAATGCATACTCCTTCCTGAGAGGGAATAGCTCAGTTAGGGCTCTTGCCACTCCCCATACTGGCCCCCATGGCTTGTCTAAATAGGACCTTGTTTCAACTTTTCTACTTACTGTGACCAGCCAACAGGTGACATATTTGTACAGCACAAACTTGCCCCAGATCAGCATGTACATGCAGCGGAACCAGAAGGGGTGGTTCTTGAGGGAAGAAAGCACAGTGCATTAGGGATATCACATGACTAGGCAGTTTCTCTCAGCACTCTTCCTTTTCACACTTGTGGCTGGCTACTTCATACCTGCCTGAGTCCTGCTGCCAGATGCCCTCAATAGTCTGGCCTGATTGCCTTCACAATAGGCAGAGAGGAATAAGCAGAGGGCCTGGAGAATATTCATTCGCCTTTCCCTTGGAGAGCCTCAAGGGCAGCACTGTATTTAACTTCTCTACTGTTTGCCTTCGTTGGCAAAGTGTTTGGAATGAGCATTTGGAATGTTAAGTACAGAGGGGCCCATATTGGATTTTAATTTAAGGAGAGAAACCTGCCCAGAATTACTGAACTGTTTTCAAGCCTTTCAGCTGGGCAGGAGCAAAAGCCAGCACTTCCCCCCTTCCCTTGGTTTCTGAATTCCCTAGAAGTGCCCAAATGTATCAGTCAAGAGAAGAAAATAGGATGGAGAATCAGAAGCTGCTGTGCTCTGAGGGGTCACGTGGATGTGATAAGGCAAGCTAGGAGCGGCTCCTAGAGAAGGCAACGGGTGCTAAATGTGCACCTGGCACAGCCCTGTGCCCGCGAAGGTTGTTCAGTGCTGGCTGATGAACATGTCCCAGCACGGCTGGCATTGACAACTCACAGATCTAGAGCAAAACCAACATGCACTTGTAGATGATATTTCCTACTTCTCTGCTATCTGTAGGGATCCTTGCCTGTCCATTTTCTAGCTCTGGTGCAGTCATGCTGCTGCTGCTTTAGTAGACACTCACGTCATAGTCTTCAGTGAGGAGATAGTCTTCTGTGATGTGGGGGCTGAGCAGTGTGTAGCCCACTAGGTAGAAAAGGCCCAGACTCAGGCGCTTGAGAGCAGGAATGATGCTGGAAAGGAACGAGTGAAGTTCCTGGTCACAGAGAGCAGAGACTATTCCCTTCACCCTCTGACCTTCAGTTATGGAGAGGAGTGTTTAGGGGTGTGGTTGTCTACCTGGAATGGGATGAGAAGCTCTGCTGCCCAAAGTGTTTCCTGTTTCAGGGAAAGATTTCTATGGCTGGCTATGAGGAATGGGGACTGCAAACCTCTTAAGAGTTGTAGGAAAGTCAGGGCAGCAGACAGTGGACCAGTCTTGTGTTTACCCCTCAGGGATGCTACTGATCTCAAGGTCTTGCCAGGTCTCACAATCTCCATTGGGACTGAAAACCCAGTGGAGGTAAGATAATAAAAATAACCACTTTGAA

Publications

PMID - Link Title
No publications available for this retrocopy