Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CDC26P1
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:129409857-129410550  UCSC
Coordinates (T2T) chr7:130722823-130723517  UCSC
Coordinates (hg19) chr7:129049698-129050391  UCSC
Strand -
Parental Sequence NM_139286.4
Parental seq. overlap 690 bp
Parental seq. overlap (%) 79.2%
Genomic Region Intragenic (AHCYL2)
Retrocopy Summary CDC26P1, located on chr7:129409857-129410550, is a retrocopy of the parental gene CDC26. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CDC26
Full Name cell division cycle 26
Also known as ANAPC12|APC12|C9orf17
Coordinate chr9:113266992-113275579
Strand -
Gene summary The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiquitin-protein ligase. APC thus is responsible for the cell cycle regulated proteolysis of various proteins. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CDC26P1
GGGAAGGGGCTAGGTCGGCTTGAAAAGAGATTATGACTGTACCTTTTAACTCTGTAGCTGGAACACAAGAAGTGTTTGTTTAATGAATGACGTACACATTTAAGATCTGTTTGGACGCTGAGGATAATCCTGTGAATTGCTAATAGTTCACTGGGTTTGGCCCTTAGTGTTGACTTCAGTATGCTGAGACGGAAACCAACACGCCTAGAGCTAAAGCTTGATGACATTGAAGAGTTTGAGAACATTCGAAAGGACCTGGAGACCCGTAAGAAACAGAAGGAAGATGTGGAAGTTGTAGGAGGCAGTGATGGAGAAGGAGCCATTGGGCTTAGCAGTGATCCCAAGAGCCGGGAACAAATGATCAATGATCGGATTGGTTATAAACCCCAACCCAAGCCCAATAATCGTTCATCTCAATTTGGAAGTCTTGAATTTTAGAGATGGATTATCTTGCATGCCAGAGCGCTGGAATGGAATAAAATGATGGCAGAAGTACAAACCAGATTTAGAGAATTGAGTGCTTGCAGTCAAGCAGAATGTACCTCCTGCAGAGACAAATCTTCTGCATGAGATTACTGATGCTTCACTTGCACTCTAAGCTGGAATCCAAACTCTGGTTTGTCTCTTGAAAATTTGACTCTATAAAACTGATCTGATTTTCTGTTTTTAAAAATAAATATATTTTTGGAAAAAA
>NM_139286.4
GTAGTAGGAAATGGCGTCGTGGCATTGAGGGGCATCCCTCCTAGAACCTCCAGGAAAAGCTCGCGGAAGACGAGGTTCTGCGGAGAGAGAGGCTCCAAGCAGTCTGGGAAGTGTAGTCCAGTTGGCTTAGCAGTAGTTTCGTTGGGGGGGAGCCGAGGTTCCGGGAAGGGGCTAGGCCGGCTTGAAAAGAGATTATGACTGTACCTTTTAACTTTGTAGCTGGAACACAAGAAGTGTTTGTTTAATGAATGACGTACACATTTAAGATCTGTTTGGACGCGGAGGATAATCCTGTGAATTGCTAATAGTTCACTGGGTTTGGCCCTTAGTGTTGACTTCAGTATGCTGAGACGGAAACCAACACGCCTAGAGCTAAAGCTTGATGACATTGAAGAGTTTGAGAACATTCGAAAGGACCTGGAGACCCGTAAGAAACAGAAGGAAGATGTGGAAGTTGTAGGAGGCAGTGATGGAGAAGGAGCCATTGGGCTTAGCAGTGATCCCAAGAGCCGGGAACAAATGATCAATGATCGGATTGGTTATAAACCCCAACCCAAGCCCAATAATCGTTCATCTCAATTTGGAAGTCTTGAATTTTAGAGATGGATTATCTTGCATGCCAGAGCGCTGGAATGGAATAAAATGATGGCAGAAGTACAAACCAGATTTAGAGAATTGAGTGCTTGCAGTCAAGCAGAATGTACCTCCTGCAGAGACAAATCTTCTGCATGAGATTACTGATGCTTCACTTGCACTCTAAGCTGGAATCCAAACTCTGGTTTGTCTCTTGAAAATTTGACTCTATAAAACTGATCTGATTTTCTGTTTTTAAAAATAAATATATTTTTGGAAAAATGTGAGGCATCCTTAA

Publications

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