Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PAXBP1P1
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr21). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:153449548-153449696  UCSC
Coordinates (T2T) chr7:154622749-154622897  UCSC
Coordinates (hg19) chr7:153146633-153146781  UCSC
Strand +
Parental Sequence NM_016631.4_2
Parental seq. overlap 129 bp
Parental seq. overlap (%) 3.3%
Genomic Region Intergenic
Retrocopy Summary PAXBP1P1, located on chr7:153449548-153449696, is a retrocopy of the parental gene PAXBP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PAXBP1
Full Name PAX3 and PAX7 binding protein 1
Also known as BM020|C21orf66|FSAP105|GCFC|GCFC1
Coordinate chr21:32733899-32771835
Strand -
Gene summary This gene encodes a protein that may bind to GC-rich DNA sequences, which suggests its involvement in the regulation of transcription. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PAXBP1P1
Bonobo Pan paniscus PAXBP1P1
Gorilla Gorilla gorilla PAXBP1P1
Orangutan Pongo abelii PAXBP1P1
Gibbon Nomascus leucogenys PAXBP1P1
Green monkey Chlorocebus sabaeus PAXBP1P1
Crab-eating macaque Macaca fascicularis PAXBP1P1
Rhesus Macaca mulatta PAXBP1P1
Baboon Papio anubis PAXBP1P1
Marmoset Callithrix jacchus PAXBP1P1
Pig Sus scrofa PAXBP1P1
Dolphin Tursiops truncatus PAXBP1P1
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PAXBP1P1
CCAGTGGAATGGCATTTTCTCAAATAAAACTCTTCTAGAATTACCAATAAATGATTTACTAGATACATTCCTATGACTTTTTAGAATTCAGGATATGGAAATGACAGCATCAACAAAGCCCAAAATGTAACCAATTGCTTTCCCAAACA
>NM_016631.4_2
GGAGAGCGCGCGTGCGCCGTCACGAGCTCGGCGCTGCCGGGGCCGCGGTGTGGAAGCGAGTATTCGACCGCCGTGCGGGCCGCGGGGATGTTCCGAAAGGCCCGGCGGGTGAACGTGCGCAAGCGGAACGACTCCGAAGAGGAAGAGCGGGAACGCGATGAGGAGCAGGAGCCGCCGCCGTTGTTGCCGCCGCCGGGCACGGGCGAAGAGGCGGGCCCCGGTGGCGGCGACAGGGCCCCTGGCGGGGAGTCGCTGCTGGGCCCGGGGCCGTCGCCGCCTTCCGCGCTGACCCCGGGCCTCGGGGCTGAGGCCGGGGGCGGCTTCCCCGGCGGCGCGGAGCCCGGCAACGGGCTGAAGCCGCGCAAGAGGCCTCGCGAGAACAAAGAGGTGCCCCGGGCCAGCCTGCTCAGCTTCCAGGACGAGGAGGAAGAAAATGAAGAAGTTTTCAAAGTGAAGAAATCAAGTTATAGCAAAAAGATAGTAAAATTGCTCAAGAAGGAATATAAAGAAGATCTTGAAAAATCGAAGATTAAGACAGAACTCAACTCATCAGCTGAAAGTGAACAACCTTTGGACAAAACAGGACATGTTAAGGATACAAATCAAGAAGATGGAGTTATCATCAGTGAACATGGTGAAGATGAAATGGATATGGAAAGTGAAAAAGAGGAAGAAAAGCCAAAGACTGGTGGAGCTTTTTCAAATGCTTTATCTTCATTGAATGTTCTTCGTCCAGGAGAAATTCCAGATGCAGCTTTTATACATGCTGCAAGGAAAAAGCGCCAAATGGCCCGAGAATTGGGAGATTTCACTCCTCATGATAATGAGCCTGGTAAAGGCCGCCTTGTTagagaagatgagaatgatgccagtgatgatgaagatgacgatgaGAAACGCCGGATAGTTTTTTCTGTGAAAGAAAAGTCACAAAGACAAAAAATTGCTGAGGAAATAGGAATTGAGGGGAGTGATGATGATGCTTTAGTAACTGGAGAACAGGATGAAGAGCTCAGCCGATGGGAACAGGAGCAGATAAGGAAAGGAATTAATATCCCTCAGGTTCAAGCCAGTCAACCCGCAGAAGTGAATATGTACTACCAGAACACTTACCAGACAATGCCTTACGGCTCATCCTATGGCATTCCTTATAGTTATACGGCCTATGGATCATCAGATGCCAAATCTCAAAAAACAGATAATACAGTCCCTTTCAAAACTCCCAGTAATGAGATGACTCCCGTTACTATTGATTTGGTAAAGAAACAGCTTAAAGACAGGTTGGACTCCATGAAAGAATTGCACAAAACAAATCGACAGCAGCATGAGAAACATCTGCAAAGCCGAGTGGACTCTACCAGGGCTATTGAAAGATTAGAAGGGTCTTCTGGGGGTATTGGTGAACGGTATAAATTTTTGCAAGAAATGCGAGGGTATGTCCAAGACTTGCTTGAGTGTTTCAGTGAAAAGGTGCCACTGATTAATGAACTTGAATCAGCAATACATCAGCTGTACAAACAGCGAGCTTCCCGCCTTGTCCAAAGACGACAAGATGATATTAAAGATGAATCTTCGGAGTTTTCAAGCCATTCAAACAAAGCTCTGATGGCACCAAATCTTGACTCCTTTGGACGCGATCGGGCACTGTATCAAGAGCATGCAAAACGTCGCATTGCAGAGCGGGAGGCCAGGAGGACTCGTCGTAGACAAGCCAGAGAACAAACCGGTAAGATGGCAGATCACCTTGAAGGCCTTTCCAGTGATGATGAAGAAACTTCTACAGATATTACTAATTTCAATCTGGAAAAAGATCGAATTTCAAAAGAATCCGGCAAAGTTTTTGAAGATGTCCTTGAAAGTTTCTATTCAATTGACTGTATTAAATCACAGTTTGAAGCATGGCGTTCAAAATACTACACATCCTACAAAGATGCTTACATTGGCCTTTGTTTGCCAAAATTATTCAACCCCCTCATACGACTTCAGCTCCTCACTTGGACTCCTCTTGAGGCAAAATGTCGTGACTTTGAGAATATGCTGTGGTTTGAATCTTTGCTGTTTTATGGTTGTGAAGAACGAGAGCAAGAAAAAGATGATGTAGATGTTGCCCTACTACCTACCATTGTGGAAAAGGTGATTCTTCCTAAACTAACAGTGATAGCTGAAAATATGTGGGACCCTTTTTCTACAACACAGACTTCAAGAATGGTGGGAATTACACTAAAATTAATCAATGGATATCCTTCAGTAGTGAATGCAGAAAATAAAAATACACAGGTATACCTAAAGGCACTTTTATTGAGAATGAGAAGAACTTTAGATGATGATGTATTTATGCCCTTATATCCCAAAAATGTCTTAGAAAATAAAAATTCTGGGCCTTACTTGTTTTTTCAACGACAGTTTTGGTCTTCAGTTAAGCTGTTAGGCAATTTTCTTCAGTGGTATGGCATTTTCTCAAATAAAACTCTGCAAGAGTTATCAATAGATGGTTTATTAAATCGATATATTCTCATGGCTTTTCAGAATTCAGAATATGGAGATGACAGCATCAAAAAAGCCCAAAATGTAATCAATTGTTTCCCCAAAcaatggttcatgaatctgaaaggagaaaggactatttctcagttagaaaacttttgccgataccttgtacacttagcggatacaatttatAGAAATAGTATCGGGTGTTCTGATGTGGAAAAAAGAAATGCAAGGGAAAACATAAAACAGATAGTAAAACTCCTTGCAAGTGTTCGAGCTTTGGATCATGCTATGTCTGTTGCAAGTGACCACAATGTGAAAGAATTTAAGTCTTTGATCGAAGGAAAATAGATCTATGAGACTGAAAAACCTATTTGCTTGATTACCATTCCCAATGTGTAAATTTTGTATATATGTAAAGTTTCTTAAACTGTAAAATAGCAATTCTTGTTTTAATACAAAAAACATTATATTCAATACTGTGTCCTTAAATGATATTTCTTCAGAATGAAAGGAATTCAGATTATTTCTAGGAGTCTATGAATGTTTTCTTTACTGCCTGTCATACTTTGTTTACTGAAGTATTTTGTATGGTCATTTAAATTAACCCTCTCAGTTAATTGTCCCCTGTAAACGATGTGTGCAGTGTAAATTGTGTAATTATGCATATATATATTTATACCACCATGGACTTACTTTCACACTGGAAATTTGTGGTGTTTTTCCACAGAGGAAGCCTTTTAACAGCAGAAAATTATCCGGTAGCAAATTGTCTTAGGGAAATTACTACACTGTTGTAACAAAAGGGCTGGCAAGTGACTAAATGTTCATTACCTTTTGGTTAGCGTTGCTATCACTGTAGCTGTGCTGCCTTAACATTGAGAGTTGAGTTGTGGACTTAGTCATTGAGTGAATGTTGAACTTTCTTCCTTGAATCAGCGTTAGAGTCAAATGTGGGTTTAATGTGAATGCTAAATGAATATGCAACATAGTTTCAAATGGAACATAGAAATTTCACTTTTGAAAATAATAAACCCACAACCTAATTGCATGGTTTTGGGCTGACCGTCCTGTCTCATTCATGATTTTACTCCCTGCCCAGCTTGCAGATACATGCATTTGAATTTTAGTAGTCTGTCATATTTAAAATCCCACATATGTGAGTTAAATATGCAATAAAGAATACGCCTTGCTGATTAGCCACACCCAGGCAATTTAATATCCATGGTCTTCTATAATGTTTATACCACATTGTAAATATTCAGAGAACTTGTTTTAAAGTTTATGCTTTCTGATTCTGTGATTTTCAAAAGAGGAATTTTTTTGGAAATTAAGGACTATCGTTTGATAATTATATATGTAATTAAGATTTAGCCAAGCATTAAATTAATTTTTAAATATA

Publications

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