| Retrocopy Name | CSNK1A1P4 |
|
| Species | Homo sapiens | |
| Coordinates (hg38) | chr7:18579407-18579598 UCSC | |
| Coordinates (T2T) | chr7:18709248-18709439 UCSC | |
| Coordinates (hg19) | chr7:18619030-18619221 UCSC | |
| Strand | + | |
| Parental Sequence | NM_001271741.2 | |
| Parental seq. overlap | 162 bp | |
| Parental seq. overlap (%) | 3% | |
| Genomic Region |
Intragenic (HDAC9) |
|
| Retrocopy Summary | CSNK1A1P4, located on chr7:18579407-18579598, is a retrocopy of the parental gene CSNK1A1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | CSNK1A1 |
| Full Name | casein kinase 1 alpha 1 |
| Also known as | CK1|CK1a|CKIa|HEL-S-77p|HLCDGP1|PRO2975 |
| Coordinate | chr5:149492982-149551439 |
| Strand | - |
| Gene summary | Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; peptidyl-serine phosphorylation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytosol; and nuclear speck. Part of beta-catenin destruction complex. Colocalizes with keratin filament and mRNA cleavage and polyadenylation specificity factor complex. Biomarker of Alzheimer's disease and inclusion body myositis. [provided by Alliance of Genome Resources, Apr 2022] |
| Species | Scientific Name | Retrocopy | |
 |
Chimpanzee | Pan troglodytes | CSNK1A1P2 |
 |
Bonobo | Pan paniscus | CSNK1A1P2 |
 |
Gorilla | Gorilla gorilla | CSNK1A1P2 |
 |
Gibbon | Nomascus leucogenys | CSNK1A1P4 |
 |
Green monkey | Chlorocebus sabaeus | CSNK1A1P3 |
 |
Crab-eating macaque | Macaca fascicularis | CSNK1A1P1 |
 |
Rhesus | Macaca mulatta | CSNK1A1P1 |
 |
Baboon | Papio anubis | CSNK1A1P1 |
 |
Golden snub-nosed monkey | Rhinopithecus roxellana | CSNK1A1P2 |
 |
Marmoset | Callithrix jacchus | CSNK1A1P2 |
 |
Mouse lemur | Microcebus murinus | CSNK1A1P1 |
 |
Horse | Equus caballus | CSNK1A1P1 |
 |
Greater horseshoe bat | Rhinolophus ferrumequinum | CSNK1A1P1 |
 |
Egyptian rousette | Rousettus aegyptiacus | CSNK1A1P1 |
 |
Sloth | Choloepus didactylus | CSNK1A1P4 |
 |
Orangutan | Pongo abelii | Without Homology |
 |
Mouse | Mus musculus | Without Homology |
 |
Rat | Rattus norvegicus | Without Homology |
 |
Chinese hamster | Cricetulus griseus | Without Homology |
 |
Rabbit | Oryctolagus cuniculus | Without Homology |
 |
Pig | Sus scrofa | Without Homology |
 |
Cow | Bos taurus | Without Homology |
 |
Sheep | Ovis aries | Without Homology |
 |
Dolphin | Tursiops truncatus | Without Homology |
 |
Dog | Canis familiaris | Without Homology |
 |
Panda | Ailuropoda melanoleuca | Without Homology |
 |
Cat | Felis catus | Without Homology |
 |
Pale spear-nosed bat | Phyllostomus discolor | Without Homology |
 |
Velvety free-tailed bat | Molossus molossus | Without Homology |
 |
Greater mouse-eared bat | Myotis myotis | Without Homology |
 |
Kuhl's pipistrelle | Pipistrellus kuhlii | Without Homology |
 |
Tasmanian Devil | Sarcophilus harrisii | Without Homology |
 |
Opossum | Monodelphis domestica | Without Homology |
 |
Platypus | Ornithorhynchus anatinus | Without Homology |
 |
Chicken | Gallus gallus | Without Homology |
 |
Turkey | Meleagris gallopavo | Without Homology |
 |
Zebra Finch | Taeniopygia guttata | Without Homology |
 |
Budgerigar | Melopsittacus undulatus | Without Homology |
 |
Painted Turtle | Chrysemys picta | Without Homology |
 |
Lizard | Anolis Carolinensis | Without Homology |
 |
Frog | Xenopus tropicalis | Without Homology |
 |
Zebrafish | Danio rerio | Without Homology |
 |
Drosophila | Drosophila melanogaster | Without Homology |
| >CSNK1A1P4 |
| TTGTTAAAGCAGAAAACAGTACAGAAGGCAGCCTCTTCCCATGGAGTTAGCATGCCCAAACTCTCACAGGTTTCCATGCATGAAGGGAGGAACAGAAGAAGCAGAATAGATAATCAGAGTAACATTTGTATATCGCCAAATCCAGAATTTTTAGTTCATATGTCGCATTGCCAGTGTTGTGAACAACCATTT |
| >NM_001271741.2 |
| CCCAGAGTGCTCTGCGCCGTGAAGAAGCGGCTCCCGGGGACTGGGGGCATTTTGTGTTGGCTGGAGCTGGAGTAACAAGATGGCGTCGTCCGCGGAGTGACAGGGGTCCCTCTGGGCCGGAGCCGGCGGCAGTGGTGGCAGCGGTATCGCCGCCCTAGCTCACCGCGCCCCTTTTCCAGCCCGCGACGTCGCCGCGCAAGCGAGGCAGCGGCGGCCGCCGAGAAACAAGTGGCCCAGCCTGGTAACCGCCGAGAAGCCCTTCACAAACTGCGGCCTGGCAAAAAGAAACCTGACTGAGCGGCGGTGATCAGGTTCCCCTCTGCTGATTCTGGGCCCCGAACCCCGGTAAAGGCCTCCGTGTTCCGTTTCCTGCCGCCCTCCTCCGTAGCCTTGCCTAGTGTAGGAGCCCCGAGGCCTCCGTCCTCTTCCCAGAGGTGTCGGGGCTTGGCCCCAGCCTCCATCTTCGTCTCTCAGGATGGCGAGTAGCAGCGGCTCCAAGGCTGAATTCATTGTCGGAGGGAAATATAAACTGGTACGGAAGATCGGGTCTGGCTCCTTCGGGGACATCTATTTGGCGATCAACATCACCAACGGCGAGGAAGTGGCAGTGAAGCTAGAATCTCAGAAGGCCAGGCATCCCCAGTTGCTGTACGAGAGCAAGCTCTATAAGATTCTTCAAGGTGGGGTTGGCATCCCCCACATACGGTGGTATGGTCAGGAAAAAGACTACAATGTACTAGTCATGGATCTTCTGGGACCTAGCCTCGAAGACCTCTTCAATTTCTGTTCAAGAAGGTTCACAATGAAAACTGTACTTATGTTAGCTGACCAGATGATCAGTAGAATTGAATATGTGCATACAAAGAATTTTATACACAGAGACATTAAACCAGATAACTTCCTAATGGGTATTGGGCGTCACTGTAATAAGTTATTCCTTATTGATTTTGGTTTGGCCAAAAAGTACAGAGACAACAGGACAAGGCAACACATACCATACAGAGAAGATAAAAACCTCACTGGCACTGCCCGATATGCTAGCATCAATGCACATCTTGGTATTGAGCAGAGTCGCCGAGATGACATGGAATCATTAGGATATGTTTTGATGTATTTTAATAGAACCAGCCTGCCATGGCAAGGGCTAAAGGCTGCAACAAAGAAACAAAAATATGAAAAGATTAGTGAAAAGAAGATGTCCACGCCTGTTGAAGTTTTATGTAAGGGGTTTCCTGCAGAATTTGCGATGTACTTAAACTATTGTCGTGGGCTACGCTTTGAGGAAGCCCCAGATTACATGTATCTGAGGCAGCTATTCCGCATTCTTTTCAGGACCCTGAACCATCAATATGACTACACATTTGATTGGACAATGTTAAAGCAGAAAGCAGCACAGCAGGCAGCCTCTTCCAGTGGGCAGGGTCAGCAGGCCCAAACCCCCACAGGTTTCTAAGCATGAATTGAGGAACAGAAGAAGCAGAGCAGATGATCGGAGCAGCATTTGTTTCTCCCCAAATCTAGAAATTTTAGTTCATATGTACACTAGCCAGTGGTTGTGGACAACCATTTACTTGGTGTAAAGAACTTAATTTCAGTATAAACTGACTCTGGGCAGCATTGGTGATGCTGTATCCTGAGTTGTAGCCTCTGTAATTGTGAATATTAACTGAGATAGTGAAACATGGTGTCCGGTTTTCTATTGCATTTTTTCAAGTGGAAAAGTTAACTAAATGGTTGACACACAAAAATTGGTGGAGAAATTGTGCATATGCCAATTTTTTGTTAAAACCTTTTGTTTTGAACTATACTGCTTTGAGATCTCATTTCAGAAGAACGGCATGAACAGTCTTCAGCCACAGTTGTGATGGTTGTTAAATGCTCACAATTGTGCATTCTTAGGGTTTTTCCATCCCTGGGGTTTGCAAGTTGTTCACTTAAAACATTCTTAAAATGGTTGGCTTCTTGTCTGCAAGCCAGCTGATATGGTAGCAACCAAAGATTCCAGTGTTTGAGCATATGAAAGACTCTGCCTGCTTAATTGTGCTAGAAATAACAGCATCTAAAGTGAAGACTTAAGAAAAACTTAGTGACTACTAGATTATCCTTAGGACTCTGCATTAACTCTATAATGTTCTTGGTATTAAAAAAAAAGCATATTTGTCACAGAAATTTAGTTAACATCTTACAACTGAACATGTATGTATGTTGCTTAGATAAATGTAATCACTGTAAACATCTATATGATCTGGGATTTTGTTTTTATTTTGAAATGGGAGCTTTTTTGTTTACAAGTTCATTAAAAACTAAAAACTGTTTCTGTAAGGAAATGAGATTTTTTTTAAACAACAAAAAATGCCTTGCTGACTCACTATTAAATAAAAATCTCCCCAATTTTTTGATAGACTACTTCAAGCCATTTGTTACATGGTATTCCTTTGCAAGTCAATTTAGGTTTCGTGTTATAACTTTTCCTCTTTTTTTAAGAAAAATGAAAAAAGTAATTCTTTTGTCTGAAGGGGAAAGGCAttctttcatttttttctttttttttttttttttttATGACTTGCAGGCACAATATCTAGTACTGCAACTGCCAGAACTTGGTATTGTAGCTGCTGCCCGCTGACTAGCAGCTGGACTGATTTTGAATAAAAATGAAAGCATTAAAGGGTTTCCCTACAAAACATTTTTCTTTAAAATACTTTTGAAATGGCTATAAGCAGTTGACTTTCACCCTTGGAGAGCATCACACTGTGTGAGGTTCAGTGATTGTTGACCCTCCCCAGCCCCTCCTGCTTCTTTAAGTTATCTGTGTGCGTGCGCTTCCTCTCAATCTTCTTTGCACGCTCATTTCTTTTTCTCTGACCCATGAGAAAGGAAAACTTACTGATGATAATTTTTAAATAGTGTAATTTATTCATTTATAGCATGTCAGGATAAATTAAAAGAACATTTGTCTGGAAATGCTGCCGGGAGCCTATTGTGTAAATGTAGGTATTTTGTAAAATAACCTTGAAATTGTAAATTGACACGTGTTTGGTCAGATTGTGTCAAGTTTAAtttgttttgttttcttttttcttttttttatttGAAAACTACTTTAGCAATAATTAATTCCATGATTATCACATTCTGCCATTAAGGGATATTAGTACCGTAATACTGAAGAAATTTTATTAAGTCTGAACTTCTGGGGTAGGCAGCTTCTTTGTTTCTTTTCTATCCACCCTTGTCGGTTGAGGTATTTGTTTCTTGACTAATAAACCCTTTGATACTTTTAGCCAGAAATCAGTCTCATAAAGCTATTTTTGAGTATAGTTTGTGTAAAATAAAAATGTTTAGCTTTGGTAATAACTTCCAAGCTGAACTCCCTCTAGCAAGATATTTTTCAGTGCTTTTATTTACTATGCACTTAGACTATGCACTTTTTCTGAAATATTTTTGTAACACTTTTTTGTATTTTTGCCATTTGAAAAGGTTGTGGTGTAGTTGGTCTGTAATTAAGTTGCAGATTTAAAACTGCTGTTAGCTTTGTAAATCAAAATATAGGTGTTTTTTGTCCTGGTATATCGTCATTCCATCTGCAGCTGGAGCTGGAATCCCATTGATCTTCTAGCTACCATTCATTTTCTTCACTGTTCACAAAAGAAGAGTGTGAAATTCAGTGAATGCTGTTACTAATCCTGTTACGAGATGAATCTCATTTCACCAAAATTAAATTATGTTTTTCCGCTAAAATGATGATACAAGTTGAAGACACATCACTCTGAAATTGGAAGACCTCACCACTTAAGGCTCCACAGTGGCTTACTCAGCTGAACTCTAGGTTACTACTCTTTACTTTGTTCACCCATTGGGGGGTGCAGTTTTTTTAAAATGTTGGGAGATGGCCATTCTAACTACTGTTGAATGTCTCTGTTTTGGGAAGGTATAACAAGAAATAAAAAAGAATATATATGAAGGGAGAGACTGGTTATCTCCTCCCATATGGTTGTGCTTATCCTCTTATGGCTTACAAATGAATATTTGGAGGTTTGCTTTCACAATGATTTCCCATCAACAAATATTTTTAGTAGGATTTTTCCTGTTTCTGTTAGTCCTTGCAGTACTCATAAATGTTTTAAGCTGAGCATACTGTAATAGTCATAAGTTTAATTTCATTATAATAAAAATAATCAAACAAAAGGACTTTAGAACCCAAGACAATGAGCTAGTTTTCCCTAAAGTTTGCTGAACTATTAAGGAATATGTTCTTATAGCTTTTGACTAGAATGAGTCATGGGAATTCTAAGAAGGGATGGCCTAGACATTTTTAGCTCAGTTAAATTCAGCATTTAATGCAGGTGAGTTCCTGGGTCGTTTTCCAACTAGTCTGGAACAGTCTGGTTCTGACTCAAACTGGTATAAAGCATTATTTTAGGTTTTCTCTTTGCCAGTTTTTAAGCAGTTATAACCATGTAAATCAAGATGTGAGGACATCTATATGAAGTATAGTAAAGAAGTGGTGTCAGCAGATCAATATGTGTGTCCTGGGTGTGCTGCTCTCTTAAGTGAGACTTTGTGAGACTATACTTTAAATGCATTATTACCATTGCTTACATTTTGGGGGATTTTCTTCCTCCTCAAAACTTCCATTTCTATTGTAATATTCTTAATGACAATCTTTTTTTTTTTTTAGCAGTGTATGTTTGAAACAGCCAAAGATGGCGATGAACCAAGTGTAAATTGATCTAAGCAGCCCATGCAGTTTGTGTTGAATCAACAAACAGTGTATTGTTGAAGTGAAATTATTTTCTGAAATGACTTGTTAGACCAGTTTTGAGGACATACTCAAAAGTAGAGTAATAATGGCTCctgggatggagaaatatgagatgaacctggaacattctattatggtgccacaaaggaaatctaaaaaaaaaaaaaaaaaaaaaagtggttggctaggagcagtggcacacgcctgtgattccagcactttgggaggccgaagtgggcaggagttcaagaccagcctggccaacatagtgaaaccctgtctctactaaaaatacaaaaattagccgggtgtggtggcgggcgcctgtaatcccagcttttcaagaggctgaggcagaagaatcgcttgaacccgggagatggaggttgcagtgagctgagatcgtgccactgcactccagcctgggcgttgcagtgagactccgtctcaacaacaacaaaaaggtggatacatgtcaaaagggcacaggagccacttgaaggattatacttgctaaatctgtgtcaattatcaaaataaactggtagcaacgtta 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