Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TUBG1P
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:43918653-43920252  UCSC
Coordinates (T2T) chr7:44076954-44078553  UCSC
Coordinates (hg19) chr7:43958252-43959851  UCSC
Strand +
Parental Sequence NM_001070.5
Parental seq. overlap 1450 bp
Parental seq. overlap (%) 89.7%
Genomic Region Intragenic (URGCP)
Retrocopy Summary TUBG1P, located on chr7:43918653-43920252, is a retrocopy of the parental gene TUBG1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TUBG1
Full Name tubulin gamma 1
Also known as CDCBM4|GCP-1|TUBG|TUBGCP1
Coordinate chr17:42609390-42615238
Strand +
Gene summary This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TUBG1P1
Bonobo Pan paniscus TUBG1P1
Gorilla Gorilla gorilla TUBG1P1
Orangutan Pongo abelii TUBG1P1
Gibbon Nomascus leucogenys LOC100602375P1
Green monkey Chlorocebus sabaeus TUBG1P1
Crab-eating macaque Macaca fascicularis TUBG1P1
Rhesus Macaca mulatta TUBG1P1
Baboon Papio anubis TUBG1P1
Golden snub-nosed monkey Rhinopithecus roxellana TUBG1P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TUBG1P
GCGTTGCGGGTGGGAGCGGCTGCAACTCTGGTGCCTGAGGAGCGATACCAAGAGAAATCATCACCCACAATTGGGCCAGTGCAGCAATCAGATTGGGTTCGAGTTCTGGAAACAGCTGTGCACTGAGCATGGTATCAGCCCCAAGGGCACCATGGAGGAGTTCGCTACTGAGGGCACTGACCACAAGGACATCTTTTTCTACCAGGCAGACGATGAGCACTACATCCCCCGGGCTGTGCTGCTGGACCTGGAGCCCCAGGTGATCCACTCCATCCTCAACTCCCCCTGTGCCAAGCTCTACAACCCAGAGAACATCTACCTGTCGGAGCATGGGGGAAGAGCTGGCAACAACTGGGCCAGCAGATTCTCCCAGAGGGAGAAGATCCATGAGGACATTTTTAACATCACAGACCAGGAGGCAGATGGTAGTGACAATCTAGATGGCTTTGTGCTGTGTCAGTTCATTGCTGGGGGGACAGGCTCTGGCCTGGGCTCCTACCTCTTAGAATGGCTGAATGACAGGTATCCTAAGAAGCTGGTGCAGACATACTCAGTGTTTCCCAACCAGGACAAGATGAGCAACGTGGTGGTCCAGCTTTATAATTCACTCCTCACACTCAAGAGGCTGATGCAGAACGCAGACTGTGTGGTGGTGCTGCACAACACAGCCCTGAACCAGATTGCCACAGACCAGATCCTGCACATCCAGAACCCATCCTTCTCTCAGACCAACCAGCTGGTGTCCACCATCATCTCGGCCAGCACCATCACCCTGCGCTACCCCAGCTACATGGACAATGACCTCATAGGCCTCATCGCCTCACTCATTCCCACCCCATGGCTCCACTTTCTCATGACTGGCTACACCCAGCTGACTATGGACCAATCAGTGGCCAGCGTGAGGAAGACCATGGTCCTGGATGTCATGAGGTGGCTGCTGCAGCCCAAGAACGTGATGGTATCCACAGGCCGAGACCGCCAGACCAACCACTCCTACATCACCATCCTCAACACCATCCAGGGAGAGGTGGACCCCACCCAGGTCCACAAGAGCCTGCAGAGGATCCGGGAATGGAAGTTGGCCAACTTCATCCTGTTGGGCCCCACCAGCATCCAGGTGGCCCTGTCGAGGAAGTCTCCTTACCTGCCCTTGGCCCACCGGGTCAGTGGGCGCATGATGGCCAACCACACCAGCATCTCCTCACTCTTCTAGAGAACCTGTCGCCAATATGACAAGCTGCGGAAGTGGGAGGCCTTCCTGGAGCCGTTCCGCAAGGAGGACATGTTCAAGGACAACTTTGATGAGATGGACACAACACATCTAGGGAGATTGTGCAGCAGCTCATGGATGAGTACCACATGGCCACATGGCCAGACTACATCTCCTGGGGCACCCAGGAGCAGTGAGTCCCCTAGGACAGGGACCCTCATCTGCCTTACTGGTTGACCAAGGCCCTGCCTGACTGACCACTCACTTAGAGCACAGATCAGGGACCTCACACATCTCTTTCTCATATACATGCATTTTCTGTTAGTCTGCGAACACATTACTTCTCCTCTTATGAGACT
>NM_001070.5
ggcgtgcggcgccgttgcgggcgggAGCGGCTGCAACGCCGGTGCCTGAGGAGCGATGCCGAGGGAAATCATCACCCTACAGTTGGGCCAGTGCGGCAATCAGATTGGGTTCGAGTTCTGGAAACAGCTGTGCGCCGAGCATGGTATCAGCCCCGAGGGCATCGTGGAGGAGTTCGCCACCGAGGGCACTGACCGCAAGGACGTCTTTTTCTACCAGGCAGACGATGAGCACTACATCCCCCGGGCCGTGCTGCTGGACTTGGAACCCCGGGTGATCCACTCCATCCTCAACTCCCCCTATGCCAAGCTCTACAACCCAGAGAACATCTACCTGTCGGAACATGGAGGAGGAGCTGGCAACAACTGGGCCAGCGGATTCTCCCAGGGAGAAAAGATCCATGAGGACATTTTTGACATCATAGACCGGGAGGCAGATGGTAGTGACAGTCTAGAGGGCTTTGTGCTGTGTCACTCCATTGCTGGGGGGACAGGCTCTGGACTGGGTTCCTACCTCTTAGAACGGCTGAATGACAGGTATCCTAAGAAGCTGGTGCAGACATACTCAGTGTTTCCCAACCAGGACGAGATGAGCGATGTGGTGGTCCAGCCTTACAATTCACTCCTCACACTCAAGAGGCTGACGCAGAATGCAGACTGTGTGGTGGTGCTGGACAACACAGCCCTGAACCGGATTGCCACAGACCGCCTGCACATCCAGAACCCATCCTTCTCCCAGATCAACCAGCTGGTGTCTACCATCATGTCAGCCAGCACCACCACCCTGCGCTACCCTGGCTACATGAACAATGACCTCATCGGCCTCATCGCCTCGCTCATTCCCACCCCACGGCTCCACTTCCTCATGACCGGCTACACCCCTCTCACTACGGACCAGTCAGTGGCCAGCGTGAGGAAGACCACGGTCCTGGATGTCATGAGGCGGCTGCTGCAGCCCAAGAACGTGATGGTGTCCACAGGCCGAGACCGCCAGACCAACCACTGCTACATCGCCATCCTCAACATCATCCAGGGAGAGGTGGACCCCACCCAGGTCCACAAGAGCTTGCAGAGGATCCGGGAACGCAAGTTGGCCAACTTCATCCCGTGGGGCCCCGCCAGCATCCAGGTGGCCCTGTCGAGGAAGTCTCCCTACCTGCCCTCGGCCCACCGGGTCAGCGGGCTCATGATGGCCAACCACACCAGCATCTCCTCGCTCTTCGAGAGAACCTGTCGCCAGTATGACAAGCTGCGTAAGCGGGAGGCCTTCCTGGAGCAGTTCCGCAAGGAGGACATGTTCAAGGACAACTTTGATGAGATGGACACATCCAGGGAGATTGTGCAGCAGCTCATCGATGAGTACCATGCGGCCACACGGCCAGACTACATCTCCTGGGGCACCCAGGAGCAGTGAGTCCCCCAGGACAGGGACCCTCATCTGCCTTACTGGTTGGCCCAAGCCCTGCCTGACTGACCACCCCCTCAGAGCACAGATCAGGGACCTCACGCATCTCTTTCTCATATACATGGACTCTCTGTTGGCCTGCAAACACATTTACTTCTCCTCTTATGAGACTATTTATCTTTAATAAAGCACTGGATATAAATCAA

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