Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name TTC4P1
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:45998839-46000821  UCSC
Coordinates (T2T) chr7:46160536-46162518  UCSC
Coordinates (hg19) chr7:46038438-46040420  UCSC
Strand -
Parental Sequence NM_004623.5
Parental seq. overlap 1848 bp
Parental seq. overlap (%) 78.2%
Genomic Region Intergenic
Retrocopy Summary TTC4P1, located on chr7:45998839-46000821, is a retrocopy of the parental gene TTC4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TTC4
Full Name tetratricopeptide repeat domain 4
Also known as CNS1
Coordinate chr1:54715861-54742657
Strand +
Gene summary This gene encodes a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. The encoded protein interacts with heat shock proteins 70 and 90. Alternative splicing results in multiple transcript variants. Naturally-occuring readthrough transcription occurs from upstream gene MROH (maestro heat-like repeat family member 7) to this gene. [provided by RefSeq, Apr 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TTC4P1
Bonobo Pan paniscus TTC4P1
Gorilla Gorilla gorilla TTC4P1
Orangutan Pongo abelii TTC4P1
Gibbon Nomascus leucogenys TTC4P1
Green monkey Chlorocebus sabaeus TTC4P1
Crab-eating macaque Macaca fascicularis TTC4P1
Rhesus Macaca mulatta TTC4P1
Baboon Papio anubis TTC4P1
Golden snub-nosed monkey Rhinopithecus roxellana TTC4P1
Marmoset Callithrix jacchus TTC4P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TTC4P1
CTTCACGGTGCCGGGACCTGGGCTGGAGGGCAGGGCATCAGTTATGGAGTAACCTGAGCAGGACCCCACCTCAGACGATGCCACGGACTTGTTCCTGGAAAAGTTCCAGAGCCAGCCTTACCGTGGCGGCTTTCATGAGGACCAGTGGGAAGAGGAATTTGAAAAGGTCCCCCTGTTTATGAAGAAAGCGCCATCAGAAATTGATCCCAGGGAGAATCCTGACTTGGCTTGTCTCCAGTCAATTATTTTTGATGGGGAGCATTCTCCAGAACAGGCCAAGACCTATAAAGATGAGGGCAATGATTATTTTAAAGAAAAAGACTACAAGAAAGCTGTAATTTCCTACACTGAGGGATTAAAGAAGAAATGTGCAAATCCTGATTTGAGTGCTGTCCTTTATACCAACCGGGCAGCAGCACAATACTATCTGGGCAATTTTCATTCTGCTCTCCGTGATGTGACAGCTGCCAAAAAGTTAAAACCGTGCTACCTCAAAGCAATAATAAGAGGTGCCTTATGCCATCTGGAACTGAAACACTTTGCCAAGGCTGTGAACTGATGTGATGAGGGACTGCAGATAGATGCCAAAGAGAAGAAGCTTCTGGAAATGAGGGCTAAAGTAGACAAGCTGAAGCTAATTGAACAGAGGGATGTGAGGAAAGCCAACTTGAAAGAAAAGGAGAGGAATCAGAATGAAGTTTTACTCCAGGATACCAAGGCTAGGAATATCAGGCTCTCTGAAGCTGCCTGTGAGGATGAAGTTTCAGCCTCAGAAGGTCTAGGTGAGCTTTTCCTGGATGGACTCAGCTCTGAGAACCCCCATGGAGCCAGACTGAGTCTAGATGACCAGGGCAGGCTGAGCTGGCCTGTGCTCTTTCTGTACCCAGAGTATGCCCAATCGGATTTCATCTCTGCTTTTCATGAGGACTCCAGATTTATTGATCATCTAATGGTGATGTTTGGTGAAACACCCTCTTGGGACCTAGAGCAAAAATATTGCCCTGATAATTTGGAGGTCTATATTGAGGATGAGGACAGGGCAGAACTGTACTGGGTGCCTGCCAAGAGCACCTTGCTGCAGGATCTACAGCACCACAGGCACTTTGTAAAAGCCCTGACACCAGCATTTTTGGTCTGTGTAGGATCCAAACTTTTTTGAAAGAATTATCTCTGGGGGAGAAAGGTGCACCAGGTAAGATGACTGAGCCAGGCCCCCTGGATCTCCTCCCTCACCCTCCTCTGCTGGGAACCTAGCATGCCTGAATCAGTCCAGTGCCTTATTTCTGTCACCCTGGGGATAGACCTTCCTAGTATCATGGTGGGGGAGGAGCCTCTGGATTCCCTGAACTGCAGCCTCTCTGGCTGGTCTTCACTTTCTTCAGTTGATATAAAACTCTGTGCCTTGGCCATGACATCCCTGGACTCCATCTCTAAAGGGACCATCTGCTGCAGTTACCACAGCAACTGACCTGACTGGCACCCTGGTCTGTGGAGACGGACTAGGGATCCAGTGACATGATTCTGAACTTTCGTGGAGTTCAACACCTTGTTACAGAAGCTACCCTTCAAACTGCATATCTACACACAAACAAACTATGCGTAGGATTCCAAGGCTTTAAAGCTGAGAGACCCTGACCTCAAGTTATTTCATGAGCACAGAGGGGAGCCATGTGGGGTTGCTGTAGATGCCTTGAGGTGAAATTGGGGCAGGAAAGCCACATCCTGCTCTGCATTTATAAAGACCATACAAACGGAGATCCTTGGTACCCCTAAAAAGATTGCCAGTTTTCTTCATCTTTGCCATATGGAGGACTGTGACAGACTTGGACAGTGGCCTCTGAGTTCCTCTGCAGTTTCACATTTTAGGATTCTGTGTCTTTTAAACTGGAAAATCTTCTAGTATGTTGGGTTGTTGTTATAAGGTATACTTTTGTCTGCAGCTGTTTGTTGCCTGCTTCCTAAGAGGGGTTTATCCATCCTGAA
>NM_004623.5
GCTCGCTTCACGGCGCTGGGACCCGGGCTGGAAGGCAGGGCATCAGCTATGGAACAACCTGGGCAGGATCCCACCTCAGACGACGTCATGGACTCGTTCCTGGAAAAGTTCCAGAGCCAGCCTTACCGTGGCGGCTTTCATGAGGACCAGTGGGAGAAGGAATTTGAAAAGGTCCCCCTATTTATGTCGAGAGCGCCATCAGAAATTGATCCCAGGGAGAATCCTGACTTGGCTTGTCTCCAGTCAATTATTTTTGATGAGGAGCGTTCTCCAGAAGAACAGGCCAAGACCTATAAAGATGAGGGCAATGATTACTTTAAAGAAAAAGACTACAAGAAAGCTGTAATTTCATACACTGAAGGCTTAAAGAAGAAATGTGCAGATCCTGATTTGAATGCTGTCCTTTATACCAACCGGGCAGCAGCACAGTACTATCTGGGCAATTTTCGTTCTGCTCTCAATGATGTGACAGCTGCCAGAAAGCTAAAACCCTGCCACCTCAAAGCAATAATAAGAGGTGCCTTATGCCATCTGGAACTGAAACACTTTGCCGAGGCCGTGAACTGGTGTGATGAGGGACTGCAAATAGATGCCAAAGAGAAGAAGCTTCTGGAAATGAGGGCTAAAGCAGACAAGCTGAAGCGAATTGAACAGAGGGATGTGAGGAAAGCCAACTTGAAAGAAAAGAAGGAGAGGAATCAGAATGAGGCTTTACTCCAGGCCATCAAGGCTAGGAATATCAGGCTCTCAGAAGCTGCCTGTGAGGATGAAGATTCAGCCTCAGAAGGTCTAGGTGAGCTTTTCCTGGATGGACTCAGCACTGAGAACCCCCATGGAGCCAGGCTGAGTCTAGATGGCCAGGGCAGGCTGAGCTGGCCTGTGCTCTTTCTGTACCCAGAGTATGCCCAGTCGGACTTCATCTCTGCTTTTCATGAGGACTCCAGGTTTATTGATCATCTAATGGTGATGTTTGGTGAAACACCCTCTTGGGACCTAGAGCAAAAATATTGCCCTGATAATTTGGAGGTCTACTTTGAGGATGAGGACAGGGCAGAACTATACCGGGTGCCTGCCAAGAGCACCTTGCTACAGGTTCTACAGCACCAGAGGTACTTTGTAAAAGCCCTGACACCAGCATTTTTGGTCTGTGTAGGATCCTCTCCTTTTTGCAAGAATTTTCTCCGGGGGAGAAAGGTGTACCAGATACGATGACTAAGCCAGGGCCCCTGGATCTCCTCCCTTACCCTCCTCTGCTGGGAACCTAGCACACCTGAATCAGCTGGACATACTGCTGGAGTCCAGTGCTTTCTTTCCGTCACCCTGGGGATAGTCCTTCCTGGCATCGTGGTGGGGGAGGAGCCTCTGGCTTCCCTAAACTGCAGCCTCTCTGGCTGGTCTTCACTTTCCTCAGTTGATATAAAACTCTGGGTCTTGGCCATGATGTCCTTGGACTCCATCGCTAAAGGGACCATCTGCTGCAGTTACCACAGCAACTGACCTGAGCGGCACCCTGGTCTGTGGAGATGGACTCAGGATCCAGTGACATGATTCTGAACTTTTGTGGAGTTTGACACCTTAGAGAAGCTACCCCTCAAACTGCACATCTACACACAAACAAACAATGCATAGGATTCCAAGGCTTTAAAGCTGAGAGACCCTGGCCTCAAGTTATTTCATGCGCACAGAGGGAAGCCATGTGGGGTTGCTGAAGATGCCTTGAGGTGAAATGGGGGCAGGAAAGCCACATCTTGCTCTGCATTTATAAAGACCGTACAAACTCAGATCCTTGGTACCCCTAAAAAGATTGCCAATTTTCTTCATCTTTGCCATATGGAGGACTGTGACAGACTTTGGACAGTGGCCTCTTGAGTTCCTCTGCAGTTTTGACATTTAGGATTTTGTGTCTTTTAAACTGGAAAATCTTCTAGCATGTTGGGTTGTTACAGAGTATATTTTTGTCTGCAGCTGTTTGTTGCCCCATTCCTAAGAGGAGTTTATCCATCCTGACTTGTAGCTGTGTGACTTCTTGCAGTGCCCCCACCCCATCCCCCCGGGAGAGTGTACTTCCCTGCTCCCAATGCAGAGGGATATGCACAGGCATGAGCTGTCCTGCGTCTGACAGAAGCCTGAAGAGTCATGTGTGGTTGGCCTGTGCTCTTCCCTCTGCTGTGAGAACACATTTCCCACAGAGGAGCCGTTCcatggagccgagctacagcagctggcctgcagccactgagtgtcacagcaatgagagagcaatgtttgctgtagtaagcagtgagatttaggggttggttgttactatagcaGAGCTAATACATGAGTAAACTGAAGCCAGCTGCTGTCCTTAAAA

Publications

PMID - Link Title