Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SAPCD2P4
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:63112453-63114873  UCSC
Coordinates (T2T) chr7:64311291-64313711  UCSC
Coordinates (hg19) chr7:62572831-62575251  UCSC
Strand -
Parental Sequence XM_011519180.3
Parental seq. overlap 1999 bp
Parental seq. overlap (%) 50.4%
Genomic Region Intergenic
Retrocopy Summary SAPCD2P4, located on chr7:63112453-63114873, is a retrocopy of the parental gene SAPCD2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SAPCD2
Full Name suppressor APC domain containing 2
Also known as C9orf140|p42.3
Coordinate chr9:137062127-137070559
Strand -
Gene summary Involved in negative regulation of protein localization to cell cortex and positive regulation of cell population proliferation. Located in several cellular components, including apical cortex; apical junction complex; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SAPCD2P2
Bonobo Pan paniscus SAPCD2P1
Gorilla Gorilla gorilla SAPCD2P2
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SAPCD2P4
GGCAGCGCCTGGTGTTAGCGCCCGCTGAAGAGCCGCGGACGGTCCTGGAGAGGAAGCCCCAGCCCCTGGGCGTGCGCGGCCATCTGGCCGTCCCAGCGGCGCGGCCCGCAGCCCGGAGCAGCTGTGCTCCCGGGCCGAGGCGGCGCCCTGCCCCGTGGAGCCGGAGCTGTCCCAGAGCACCGCGCTGGAACCGAGCCGGAGTGCAGACGCAGGTGCAGTGGCCTGCAGGGCCCAGGGCCAGGGAGGCGGACTCAGGGGATGCCTGGCGGGCCTCCAGTGCCCCAGGGGAACGTCGGAGTCACACCATCACCAGCGGTATGGACTGCGGCCTGCTGAAGCAGATAAAGAAGCTGGAGCAGAGAAGGCTGTGCAGTTGCAGGCTTTGGAGATGACGGCGCGGGGCCGCGGCTGGTACCAGCAGCAGCTGCAATGAGTGCAGGAGCACCAGCACCGACTATGGGGCTGCGGGAGCCCCCGCCCACTGGGGCGGCTACTGCCCAAGGTACAGGAGGTGGCCTGGTGCCTGAGGGAGCTGCTGGCTGCGGCCTGTGCCAGCCAGGCCCTGTCCAAGTCCTCCTCCGCCCCCCACCCGGTCCTGCCCGCACGTCCACTTCGTCCCTGGGCCGGCAGCAGCAGACCATCCTCATGCTGAATGAGCAGAACCGACTCCTCACCCAGGAGGTGACAGAGAAGAGTGAGCGCATCACGCAGCTGGAGCAGGAGAAGTCAGCACTCATTAAGCAGCTGTTTGAGGCCCGCGCCCTGAGCCAGTGGGACGTGGGCGCCTCTGGACTTCATCTAGTCCGTGTGGGCAGCGCGGGCCCCCAGGGCCGGCCTGGCACTCAGCCCTTCGAGGTTGGGCGCCCCATCACACCCACCTTCTCTGGCTGGAGACCCCCGGCAGGCCCAGACAGTCCCAGAGTGGGCGCCTTCCTGCCCGCATTGCCAAATGGGCTCCCCAGGCCTGCCCCCGGCTGGTCCCCACACCAAACCCTTGACTCCGTTTTAGCTCCTGGTGCTGACATGGGCTGGGGCTGTCTTGAGTCTGCATAGTCCGCAGCTACTACTGCCGCTGTCAGTGGACAGTGGGGATCACCTCCACAAGTTACCATCCCCCATTTCCAGCTGTGCTGCCCTGGGTCCCATCTACAGGGAAAGGCACTGCTCACGCCAGGCTGCACTTCCAACAACTGCCAACAGAAGGCGCTGCGCGGCTCCGATGCGGGTCCAAGGGCAGCTTCCCCCCTCAACCAGGGCACCAGGACAAGGTAGCTGTCACTCTAACGGAAGCAGATGGAGGGGGTGGGGATGACCTGTAAGCGGGGGGTGCCCGCCTGGCCGGGTAGACCCAGGGATGGCGCTCGGACTTCAGGTCCTGGCCAAGGCTGAGGGACTCTGGCTGCAGTGGATCGGGGAGCCGGGTGGGCGAGATCTTAGCCTGCATGTATCTCCCGCAAACCCCGGGGTGATGGCTTTCCTCATCCTGGCCAGGACACTGCCCCACGTTGAGTCCCACACAACAGTGTGTGAGCCTGGCTCCCCAGGAGGGCCCCCAGACAGCTCCCAGGCACATCATAGGCCTGCCCCCCAACCCCCCCAAACACACACTCAGGATTCCCAAGGTTTGGGGTCCTGCTCACCCCCGTTTCCTCTCACACCCAGCCCGACCCCAAGTTTCAGCAGGGAGAGGCCACTTCCCTCAGCCAAGGAAAACGAGAACCCCTACAGTACAGGAGGAGGCTGGGGCAGGTCCCCTTGGGTGTCAATCCCTGCCCCCCAATCCAGGTCCACTCCCGCTGGAACACACTGGTGGGGGGGCCCTGCTCAGCCCAGCCTGGAGGGTCCCAATGCCACCAGAGCCAGGGGCACAGAAACATCATGGATGGGTTCTGCAGCCCAGGGTCCCCGATCCAGGGTCAGTGTGTGTGGGGCGCAGGGACCCTGATGCGGGGTCATTGTGTGTGGGGCGCAGGGAAGCACTGAGGGGCTGCCGCGCGCCTTGCTGCAGAGCCTGCACACCCTGTTCCACATCTGGACAACAGGCGGTGCGGCTGCAGGCACCTGCACGAGATCCAGTCTCGCTGGCAGGGCGCCAACACGTGGGAGCAGCCACGCGGGGTGCTGGAGGGCTTGTGCCAGGTGGCCCAGGCCAGCGGCTACTTGACCTTCGAGCGCTTCGTGGCCGGCTTGCGCACCACGCTGCTGAGCCCGATGGCGGCCCCTGGGACCCCACATGCGCCCTGGCCGGGACCAGGGACCAGGGCCGGCCCCTCCATGGGGCCGCCCGGGAACACACGCGGGTGGAGGAGGGGAc
>XM_011519180.3
TCGCTATTGTCGCCGTGGGCTGAGCTCGCCGGGCCGGCCCCTCCGTGGGGCCGCGCTGGGACGCACGCGGGTGGACGAGGGGACCGATCCCGGGCGCCCATGGCCGGGGCCGCCATGGCCGAGCGGGGCCGCGTGCCTCCCCCCGCACCCGCGCCCAGCACGGAGGGGCTGCCGCGCGCCTTCCTGCAGAGCCTGCGCACCCTGTTCGACATCCTGGACGACCGGCGGCGCGGCTGCGTGCACCTGCGCGAGATCGAGTCCCGCTGGCAGGGCACCGACGCGCGGGAGCTGCCCCGCGGGGTGCTGGAGGGCTTGCGCCAGGTGGCCCCGGCCAGCGGCTACCTGACCTTCGAGCGCTTCGTGGCCGGCCTGCGCACCTCCCTGCTGAGCGCCGACGGCGGCCCCCGGGACCCCACGCGCGCCCCGGCCCGGCCCGGGGATCAgccgccgccgccgccgcagcgccTGGTGTTCGCTCCGGCCGACGAGCCGCGGACGGTCCTGGAGAGGAAGCCCCTGCCCCTGGGCGTGCGCGCCCCTCTGGCCGGTCCCAGCGCCGCCGCCCGCAGCCCGGAGCAGCTGTGCGCCCCGGCTGAGGCGGCGCCCTGCCCCGCGGAGCCCGAGCGGTCCCAGAGCGCGGCGCTGGAACCGAGCTCCAGCGCGGACGCAGGGACGGGACCGGGGAGCGGCTCTTCGTGGACTCCGGATCCTGGAGGGCGCCTCGGCGGGTCTGGAGGGAAAGGGCTTCATGCTTGTCGCGGTGCAGTGGCGTGCAGGGCCCTGGAGGCGGACTCAGGGGATGCCCGGCGGGCTCCCCGTGCCCGAGGGGAACGTCGGAGGCACACCATCGCCAGCGGCGTGGACTGCGGCCTGctgaagcagatgaaggagctggagcaggagaaggagGTGCTGCTGCAGGGTTTGGAGATGATGGCGCGGGGCCGCGACTGGTACCAGCAGCAGCTGCAACGAGTGCAGGagcgccagcgccgcctgggccagagcagagccagcgccGACTTTGGGGCTGCAGGGAGCCCCCGCCCACTGGGGCGGCTACTGCCCAAGGTACAAGAGGTGGCCCGGTGCCTGGGGGAGCTGCTGGCTGCAGCCTGTGCCAGCCGGGCCCTGCCCCCGTCCTCCTCCGGGCCCCCCTGCCCTGCCCTGACGTCCACCTCACCCCCGGTCTGGCAGCAGCAGACCATCCTCATGCTGAAGGAGCAGAACCGACTCCTCACCCAGGAGGTGACCGAGAAGAGTGAGCGCATCACGCAGCTGGAGCAGGAGAAGTCGGCGCTCATTAAGCAGCTGTTTGAGGCCCGCGCCCTGAGCCAGCAGGACGGGGGACCTCTGGATTCCACCTTCATCTAGTCCTTGTGGGCCGCGTGGGCCCCCAGGGCCAGCCTGGCACTCAGCCCTTCGAGGGTGGGCGCCCCATCGCACCCACCCTCTCTGGCTGGAGACCCCCGGCAGGCCCAGGCACAGTCCCGGAGTGGGCGCCTTCCTGCCGCCCTTGCCAGATGGGCTCCCCAGGCCTGCCCCCGGCTGGTCCCCGCACCGAGCGCTTGACTCCGTTTTGGCTCCTGGTGCTGACATGGGCTGGGGCTCTCTTGAGTCCGCATAGTCCGCAGCTACTACTGCCGCTGTCAGTGGACAGTGGGGTACCCCTCCATGAGTTAGCGTCCCCCCGTTTCCAGCGGTGCCGCCCTGGGTCCCATCTTCAGGGAAAGGCACTGCCCACGCCAGGCTGCACTTCCAACAACGGGCAGCAGAGGGCGCGGGGCGGCTCCGACGCGGGTCCAAGGGCAGCTTCCCGCTCAACCAGGGCACCAGGACGAGGTGGCTGTAGCTCGGACGGACGGAAGTAGATGGAGGGGGTGGGGACGGCCTGTAAGCGGGGGGTGCCTGCCTGGCTGGGGAGCCCCAGGGATAGCGGTCGGACTTCAGGTTCTGGCCAAGGCTGAGGGACCCTGGCTGCAGCGGATCGGCACGCCGGGTGGGCGAGAGCTTGGCCTGCATGTGCCTCCCACAGACCCTGGGGTGATGGCCTTCCCCCTCTTGGCCGGGACGTTGCCCCACGTTGAGTCCCACACAACATCCTGTGAGCCTGGCTCCCCAGGAGGGCCCCCAGACAGCTCCCAGGCACGTCATAGGCAAAGCCTGTTCCCCCGACTCAGGATTTCCAAGGCCTGGGGTCCTGCTCACCCCCCTTTGCTCTCACGCCCAGCCTGTCCCCAGGTTTCAGCTGGGAGAGGCCACCTCCCTCAGCCAAGGAAAACGAGAACCCCCAGGGTACAGGAGGAGGCTGGGGCAGGTCCCCTTGGGTGTCACTCCCTCAGCCCCTGCCCAGGCCCACTCCCGCTGGTGCTGGAGTACGCACTGGTGGGGGGGCCCTGCTCAGCCCAACCTGGAGGGTCCCAGTGTCACCAGAACCAGGGGCACGGCAACAGCATCGATGGGTTCTGCAGCCCAGGGCCCCCGATGCGGGGTCAGTGCGTGGGGGGCGCAGGGCCCCCGATGCCGATGCGGGGTCAGTGTGTGTGGGGCGCAGGGCCTCCGATGCGGGGTCAGTGCGTGGGGGGCGCAGGGCCCCCTCGTGTCCAGGGCACTTTGGTACACTGTCCCACAAGGCACCTGTCTCAGAGGAGGGGCCCTGGCAGGCAGCGTGGCAACTCCCTTCCGGAGCCCAGCTCCATGCTAACCTGCCCACAGCAACCCCACAGAGCCACATTCCCTGCTGCACCTGGTCTGCAGGGGTGTCCCAGGACAGGCCCAAGTCAGCCCAGCATGCAGCTGCCCTCCTACCCTGAAGATGGGAGTGGGCTTTCCAGGGGACATAAGGATGTCAGGCCTGGACCTCCTGGGCAGGAAAGGGTGCAGGTCCTGAGGGCCTGTGCCCCACAGCCCCAGCACCAGGTGGACTGCAGCGCAGTGGGTGGGCCAGTGGCAGCCAGGGAGAAGCCCCCCGTCAGCAGGCTGGGGTCTGCCCACCAGGGCCTCCCCACGTCTGCCTTTGAGGGTGCCTGCCATGCCCTGGGGGATCCTGGCATCTTTACTGGACTGGAAGCAGGAGACAGAACAGTGTCTGTCCCGGGGTGACTTCATCAGGAGACCGCCCACATAGAGCTGGACCCCGCAGCTGAAGCGGAAATGTGAGACAGGCTGGCACCTCCGGAAAAACTGCCTTTCAGCCTTGGTGTTCCGTGCAAGGTGAAAAGAAATAGGTCCTCCCAGTTTACAGCTTGAAATCAGGCTAGTGAGTGGCCCTGGAGACCACGAGGGGAGAATTTAAAGGCCCCGGCTGGCAGGGTCTAGGTGGCTGGCAGAGGCACATGCAGACCCTGCCTGGAGCCTGCCCTAGGACGCTGGGCGGGTCAGTCTCCGtgcaggatgtgagcagcgtccctgggctctatccgcgaggtgccagtagcgtgtgcaggtacatacacgtgcgtgcacactgtgatgacacccggaaatgtctcaggatgttgaaatgtgtccttgggggcagaagtgtccccagttgagaatcTGCCCCAGAGGAACACACCCACACCAGGCCTCAGGATTTTGTGTTGATCAAGTTCCAAGGAAAAGGAACATCTCAgccgggcgtggtggttcacgcctggaatcccagcacttgaggccaggagttccagagcagcctgggcaacgcagtgagagaccccatctctacaaaaaaaaaaaAGAAAGAAAGAAAATGAGAGATCCAGGTTTAaaaattcataaacaccacaaggaaacaatacactatgagacccagcagaagcaacagattgactctagacccagatactagaattatcagagagaatataaagtaacagtgttttatatatctaaagaaataaaagagatttctggaaacatgaa

Publications

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