Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NUP35P2
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:79543966-79544816  UCSC
Coordinates (T2T) chr7:80795741-80796591  UCSC
Coordinates (hg19) chr7:79173282-79174132  UCSC
Strand -
Parental Sequence XM_017003308.1
Parental seq. overlap 727 bp
Parental seq. overlap (%) 40.3%
Genomic Region Intergenic
Retrocopy Summary NUP35P2, located on chr7:79543966-79544816, is a retrocopy of the parental gene NUP35. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NUP35
Full Name nucleoporin 35
Also known as MP-44|MP44|NP44|NUP53
Coordinate chr2:183117480-183161680
Strand +
Gene summary This gene encodes a member of the nucleoporin family. The encoded protein contains two membrane binding regions, is localized to the nuclear rim, and is part of the nuclear pore complex. All molecules entering or leaving the nucleus either diffuse through or are actively transported by the nuclear pore complex. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 7 and 10. [provided by RefSeq, Dec 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NUP35P2
Bonobo Pan paniscus NUP35P2
Gorilla Gorilla gorilla NUP35P1
Orangutan Pongo abelii NUP35P1
Gibbon Nomascus leucogenys NUP35P1
Green monkey Chlorocebus sabaeus NUP35P2
Crab-eating macaque Macaca fascicularis NUP35P1
Rhesus Macaca mulatta NUP35P1
Baboon Papio anubis NUP35P1
Golden snub-nosed monkey Rhinopithecus roxellana NUP35P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NUP35P2
TGGGATCTGAACCAGTGACGGTGAGTTCATCCATCCACATCTCCAAAGCCAGGAGATAATGTCCACTTCTTACCTGTCTTTTTAATGATGGATTTTCCAGTGAGTCTATAAGTTCAATCAATTAGTGGTCCTAGTACGAGTAATGGAAATGAGATCATGTTTACTTGCAGGTGGCTCATCACGGCCATAGTCAGTTACACCAGCTTATAAAGATAAAAGTGGAGCTCCACCAGTTAGAAGTATATATAAAATGACATTTTTAGACCAGGGCTTGGATCAACACTTTTAGTTTCAAGAAGAGAGTCAAACATTTTATTAATGCAGAGTCCTCTTGTTGGAGTTAAGACAACTACTCCTGCAACTTGGCAAAGTATGTTTAGTCTAGCACATATCAGTCAGCCATGAAAGACAGCATTATCTCCCGCCCACTTGGAACCTTTTATACTCAAGGATATCCTCTGACTTCAGAATATCACCTCAATGACACTTGAGTGATTGTGTTTGGGTTTCCTCAAGCACCTGCTTTTTACATATTATAATTTGCATACTATGGGAATATCTTAAAATACGTTATGTCTAACACACAGGAAATTGCATATTTGTTATTAATCTAAACTGTAGGCCTAGAAAGCCTTAAGCAAAGACAGGAGAATTTTTAGAGAATTCATCATGATTGGTGTACAACCATGTTTTGATGCAAGTGTTACAGAAAACAGTGACAGATGTGCTTTATCATCCCCATCTTCAGCCTTTACATCACCAATCAAAACCTTAGATAAACCAATACAACCTGGAAATACTTCTAGAATTTCTACCCTGAGACCTCTTGCTACAGCATACAGAGCTTCTAT
>XM_017003308.1
CATTTGAGATTTTAGGAAGTCCTAGAAGAAATAGCTGAGCATGGGTGGATATTTTGGAAATAATCCTCATGGTATGGAGCAGAGAACGTCCCCAGTTATACATATGTAGCACATTATTTTATAAAGTTAGTATTTGAGCAAAACTAAACAATATATTTTTACACACACATATGCAGAATATGTGTATGTGATTTACGTATGACTATGCCCTAAAGAAAAGCAGCAAAGTGAGGGGACGTGGACGGCAGGGATGGCACATGCAGAAGCACGCAAGATTCCGCGGTGTGGAGGGTTCGTGGGATCTGAACCAATGATGCTGGGTTCACCCACATCTCCAAAGCCAGGAGTTAATGCCCAGTTCTTACCTGGATTTTTAATGGGGGATTTGCCAGCTCCGGTGACTCCACAACCTCGATCAATTAGTGGCCCTTCAGTAGGAGTAATGGAAATGAGATCACCTTTACTTGCAGGTGGGTCACCACCACAACCAGTTGTACCAGCTCATAAAGATAAAAGTGGCGCTCCACCAGTTAGAAGTATATATGATGACATTTCTAGCCCAGGACTTGGATCAACACCTTTAACTTCAAGAAGACAGCCAAACATTTCAGTAATGCAGAGTCCTCTTGTTGGAGTTACATCTACTCCTGGAACAGGGCAAAGTATGTTTAGTCCAGCAAGTATCGGTCAGCCACGAAAGACGACATTATCTCCTGCCCAGTTGGATCCTTTTTATACTCAAGGAGATTCTTTGACTTCAGAAGATCACCTCGATGACTCTTGGGTGACTGTATTTGGGTTTCCTCAAGCATCTGCTTCCTACATATTACTACAATTTGCACAGTATGGGAATATCTTAAAACATGTGATGTCTAATACAGGAAATTGGATGCATATTCGTTATCAATCTAAACTGCAGGCTCGGAAAGCCTTAAGCAAAGATGGGAGGATTTTTGGAGAATCCATCATGATTGGTGTAAAACCATGTATTGACAAAAGTGTTATGGAAAGCAGTGACAGATGTGCTTTATCATCTCCATCTTTAGCCTTTACACCACCAATCAAAACTCTAGGTACACCAACACAACCTGGAAGTACTCCTAGGATTTCTACCATGAGACCTCTTGCTACAGCATACAAAGCCTCTACTAGTGATTATCAGGTTATTTCTGACAGACAAACGCCAAAAAAAGATGAAAGTCTTGTATCCAAAGCAATGGAGTACATGTTTGGCTGGTAGTAGAACACCAAGAAGGAGGTTGCTACACTAAAACAGAGTTAGCAGAGTGCTGCTGGTTCCTTCGGTTAGTTATATAACTGTTCCTGCAGTATTGGATAGCTATCTCATACTTCTTTTAGAAAGAAGCCTTTTTCATTAAGGATACAACCTATTTGTAGCTCGCACTTTAAAAGATGCTTGAGATACATTTTAAAGAAAACTAAAAATCCCTGTAAATAGGATTTTGTGCTTTCTGTAACAGTGCATGCTTCAGCACAGAAAACTCAGCATTGATTATTGTAAATTAAATAACTGAAATTGTGGTGAGACGTCATAGTCTTCATGAGAACGTGGGGGTGAATTTCATGAAGGGGAACTATAGTTATTTCTACCGACACAAATATTATAATTAGCAATTTGAATTATGGTCTTTTAATTTAGATAGTATTTAATATTTTAATTATCCTTGTTTGTATATGTCCTGTCACAGAGTGTCCTCTTGGTGTATTCTAAAACGAGCATTCTTTTAAAAAACCTAAAGTTTCTTGATAATAAACATTGTCAATGATA

Publications

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