Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SNRPBP1
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:80377412-80377831  UCSC
Coordinates (T2T) chr7:81628743-81629162  UCSC
Coordinates (hg19) chr7:80006728-80007147  UCSC
Strand -
Parental Sequence NM_003091.4
Parental seq. overlap 364 bp
Parental seq. overlap (%) 33.6%
Genomic Region Intergenic
Retrocopy Summary SNRPBP1, located on chr7:80377412-80377831, is a retrocopy of the parental gene SNRPB. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SNRPB
Full Name small nuclear ribonucleoprotein polypeptides B and B1
Also known as CCMS|COD|SNRPB1|Sm-B/B'|SmB/B'|SmB/SmB'|snRNP-B
Coordinate chr20:2461642-2470789
Strand -
Gene summary The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SNRPBP1
Bonobo Pan paniscus SNRPBP1
Gorilla Gorilla gorilla SNRPBP1
Orangutan Pongo abelii SNRPBP2
Gibbon Nomascus leucogenys SNRPBP1
Green monkey Chlorocebus sabaeus SNRPBP1
Crab-eating macaque Macaca fascicularis SNRPBP1
Rhesus Macaca mulatta SNRPBP1
Baboon Papio anubis SNRPBP1
Golden snub-nosed monkey Rhinopithecus roxellana SNRPBP1
Marmoset Callithrix jacchus SNRPBP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SNRPBP1
TGATGGGCCTACCTCCTGGTGTCAGGCCTCCTATGGTCCCCCAGTGGGGATCTCCCCTGGGAGACAGACTCCAGTGGGCATATCCCCTCTGGGAATGCAGCCTCCTCCCCATGGGATGCGAGGCCGTCTTTGACCCTTGGCCACAGAGTATGGAAGTAGCTCCACAGAGACATGGGCTCAACTCCTCAGGGCCACATTACCACAGACCTATTTGTTTGTTATGCTGCTGTTCACGGAGTCTCTCCAGATTGTCTGGTTTTCCTTACAGAGCCCCATCCCCTGAGAATGTGCCCATCAAGACCCTAGACTCATCTTGGCCCTCCTAGCTCCCTGCCTCTTTCCTGAAAGGCTGTACATAGTCCTTTTATTTCCTTGTGGCCCATGAAACTGGTTTATAATAAACTCTTa
>NM_003091.4
GCATTTCCGGTAGCGGCGGCGGGAAATCGGCTGTGGGAGAGAGGCTAGGCCTCTGAGGAGGCGAATCCGGCGGGTATCAGAGCCATCAGAACCGCCACCATGACGGTGGGCAAGAGCAGCAAGATGCTGCAGCATATTGATTACAGGATGAGGTGCATCCTGCAGGACGGCCGGATCTTCATTGGCACCTTCAAGGCTTTTGACAAGCACATGAATTTGATCCTCTGTGACTGTGATGAGTTCAGAAAGATCAAGCCAAAGAACTCCAAACAAGCAGAAAGGGAAGAGAAGCGAGTCCTCGGTCTGGTGCTGCTGCGAGGGGAGAATCTGGTCTCAATGACAGTAGAGGGACCTCCTCCCAAAGATACTGGTATTGCTCGAGTTCCACTTGCTGGAGCTGCCGGGGGCCCAGGGATCGGCAGGGCTGCTGGCAGAGGAATCCCAGCTGGGGTTCCCATGCCCCAGGCTCCTGCAGGACTTGCTGGGCCAGTCCGTGGGGTTGGCGGGCCATCCCAACAGGTGATGACCCCACAAGGAAGAGGTACTGTTGCAGCCGCTGCAGCTGCTGCCACAGCCAGTATTGCCGGGGCTCCAACCCAGTACCCACCTGGCCGTGGGGGTCCTCCCCCACCTATGGGCCGAGGAGCACCCCCTCCAGGCATGATGGGCCCACCTCCTGGTATGAGACCTCCTATGGGTCCCCCAATGGGGATCCCCCCTGGAAGAGGGACTCCAATGGGCATGCCCCCTCCGGGAATGCGGCCTCCTCCCCCTGGGATGCGAGGCCTTCTTTGACCCTTGGCCACAGAGTATGGAAGTAGCTCCGCAGAGGCGTGGGCTCGATTCCTCAGGGCCACGTTACCACAGACCTGTTTGTTTCTTATGCTGTTGTTCGTGGAGTCTCATGGGATTGTCTGGTTTCCCTTACAGGGCCCCCTCCCCCGGGAATGCGCCCACCAAGGCCCTAGACTCATCTTGGCCCTCCTCAGCTCCCTGCCTGTTTCCCGTAAGGCTGTACATAGTCCTTTTATCTCCTTGTGGCCTATGAAACTGGTTTATAATAAACTCTTAAGAGAACATTA

Publications

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