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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CHCHD4P6
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:92442067-92442526  UCSC
Coordinates (T2T) chr7:93683381-93683840  UCSC
Coordinates (hg19) chr7:92071381-92071840  UCSC
Strand +
Parental Sequence NM_001098502.2
Parental seq. overlap 360 bp
Parental seq. overlap (%) 25.1%
Genomic Region Intergenic
Retrocopy Summary CHCHD4P6, located on chr7:92442067-92442526, is a retrocopy of the parental gene CHCHD4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CHCHD4
Full Name coiled-coil-helix-coiled-coil-helix domain containing 4
Also known as MIA40|TIMM40
Coordinate chr3:14112077-14124870
Strand -
Gene summary CHCHD4, a component of human mitochondria, belongs to a protein family whose members share 6 highly conserved cysteine residues constituting a -CXC-CX(9)C-CX(9)C- motif in the C terminus (Hofmann et al., 2005 [PubMed 16185709]).[supplied by OMIM, Mar 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CHCHD4P3
Bonobo Pan paniscus CHCHD4P3
Gorilla Gorilla gorilla CHCHD4P3
Orangutan Pongo abelii CHCHD4P3
Gibbon Nomascus leucogenys CHCHD4P3
Green monkey Chlorocebus sabaeus CHCHD4P3
Rhesus Macaca mulatta CHCHD4P3
Baboon Papio anubis CHCHD4P2
Golden snub-nosed monkey Rhinopithecus roxellana CHCHD4P2
Marmoset Callithrix jacchus CHCHD4P7
Crab-eating macaque Macaca fascicularis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CHCHD4P6
TGCTGCAGCCATGTCCTACTGCCAGCAGGAAGGGAAGGATGGAATCATATTTGTGACCAAAGATGACCACAAAACTCCAAGCAATGTAGAGCTGGTGGCTGATGACCCCAACAATCCATACACAGCATGGATTGATGCTGCCAAATGAAGACATTAACTGGAACTGCTCGTGCCCTGGGGGAATGGCCAGTGGCCCCTGTGGGGAACAGTTCAAGTTGGCCTTTTTCTGCTTCCACTATAGTGCAGAGGATCTCAAGGGGAAAGACTGTGTAGATGAATTCCGGGTCATGCAGGAATGCATGTAGAAACACCTGGACCTCTATCCCCaACTGCTCCCACTGAGGCCACTGCAACCAAAGAAGAGGTGCGGACAAGTTAATGAAGTCCACAAGGCACCGGGCTCCAGTCCTT
>NM_001098502.2
AGTTTCCGGCTGAGGTTGGCCTGGCCGCGGTTGCGAGGGCGCCGAGGCAGGCGCGCGGCGGGCAGGCCTGGGAGGGGGCGGGTCCGCGCGGGCTTCGGAGGAGCCCGCCCTGCCAGAGGAGAGGGAGGTCACGGCGTAAAGGTGCAGCTGCCGCCACCGCCGCTTCTGCAAGGTCTCAGGGACGGGCTGCAGCCATGTCCTATTGCCGGCAGGAAGGGAAGGATCGAATCATATTTGTAACCAAAGAAGATCATGAAACTCCAAGCAGTGCAGAATTGGTGGCTGATGACCCCAACGATCCATACGAGGAGCATGGATTGATACTGCCAAATGGAAACATTAACTGGAACTGCCCATGCCTTGGGGGAATGGCCAGCGGTCCCTGTGGAGAACAGTTTAAGTCAGCCTTTTCCTGCTTCCACTATAGCACGGAGGAGATCAAGGGGTCAGACTGTGTAGACCAGTTCCGGGCCATGCAGGAATGCATGCAGAAATACCCAGACCTCTATCCCCaagaggatgaggatgaggaagaggaaagagagaagaagccagcagaacaagcagaagaaACAGCTCCCATTGAGGCCACTGCAACCAAAGAAGAGGAGGGATCAAGTTAATGAAGGCCACAAGGCACTGGGCACCAGTCCTTTTGGAGTGGACCTTTTGCAAAAGGCCTTGTCATCACCTTCCAAGAAAGTTTCCTTCTGTTGTCCTGTGCATTATAATATACAAAATAACTTATTTTGATGATCAGAGGTCTTGAGGTCTTGACATCTTGACATATACACTGAAAAAAATGGGGGTTGTATGTATGTGTGTCCTACCCAAACCTGTGGCCGCCACTTTTGAATTCTCAGATTGCCCTGAATTTTGCCACTTTTAAATAATGTGCTGAATAAGCTCAGCAACTAAAAACCATTACCCAAGAACGTTTCTTGTGAGTGAGCTGATTTATTCTGATTCATTATATTCCTTTTGGTAGATTTTATACCCCTTGGGGAAATAATACAACAAAAACATCTCTTAAAAATGCTGGGATGGGGCCATATCTACTAGCAGAGGCCAGATGGTCAGATATGATTTCTGCAAACCCATCTTGACCTTGAGTATGTGAAGGGGTACTGTACTTTATTCCTGATACATTTTGGTTTCCATGTAGGTGTTGAGCTCCTGGTTTTCTGTGTTTGGATGATGAAGATTTGGACCCTTCCATTCATAATCCCTTTCTAAGTGAAGGGAGAGGCTGGCTTGGCTGTTCCTTGTTATTCCGAAAGCCCTGGTTTGGGGCCCATGTTCACACTGGCTCTCAGTCTAGTCAGGTGCAATGTTCTTGAGAGGTGGGGACCTAATTATTACCAGAGTAGCAGCAAGAGAGGAAACGTTGTGAATTAAGTATTCAATTAAAAGGAAACATGATTTCTACCTGA

Publications

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