Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GRPEL2P3
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:94782845-94783954  UCSC
Coordinates (T2T) chr7:96018730-96019839  UCSC
Coordinates (hg19) chr7:94412157-94413266  UCSC
Strand +
Parental Sequence NM_152407.4
Parental seq. overlap 1016 bp
Parental seq. overlap (%) 25.3%
Genomic Region Intergenic
Retrocopy Summary GRPEL2P3, located on chr7:94782845-94783954, is a retrocopy of the parental gene GRPEL2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name GRPEL2
Full Name GrpE like 2, mitochondrial
Also known as Mt-GrpE#2
Coordinate chr5:149345499-149354583
Strand +
Gene summary Predicted to enable adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes GRPEL2P1
Bonobo Pan paniscus GRPEL2P1
Gorilla Gorilla gorilla GRPEL2P1
Orangutan Pongo abelii GRPEL2P1
Gibbon Nomascus leucogenys GRPEL2P2
Green monkey Chlorocebus sabaeus GRPEL2P3
Crab-eating macaque Macaca fascicularis GRPEL2P1
Rhesus Macaca mulatta GRPEL2P1
Baboon Papio anubis GRPEL2P1
Golden snub-nosed monkey Rhinopithecus roxellana GRPEL2P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GRPEL2P3
GGCAAGTGCGCATGCACTGCCTCCATCAACCCAAGTCAGGAACATGGCCGTGTGGTCGCTGTGGGTGGGCAGGCACCAGGTGCAGCACCTACTGGCCTCGAGTGCCTTGTAGGAGAGCAAGGGATGGCCGCTTCCATTCTGCACGGCCACCCTGATAACTGCTGGTGTGGACTGCTGTTCTGAGGACGCTCCTGATGAGCTTGGGCCCTCTCTTGCCCAACAAGCCTTAAGGGTAAAGCTGTTAAACTGGAGAAGGAAGTCCAGGATTTAACCATGAGATAGCACAGAGCTGTAGCTGATTGTGAAAACATAAGGAGGCAAACCGAGAGATGTGTGGAAGATGCCAAGATAGGTGGCTGACATTTTGGAGACGACTACACAGTAAATTTCTGAAGAATCAGAGCCTGGGAACCAGAAGCTCACTCTGGAGAAGGTCTTCCGAGGGTTGTCACTTTTAGAAGCAAAGCTGAAAAATGTGTTTGCCAAGCATGGCCTGGAGAAGCTATCACCCATTGGTGACAAATATGACCCCCAAGAGCATGAACTCATCTGTCATGTGACAGCTGCTGTTGGGGTGCAGCCTAGCACCGTGACATTAGTAAGACCAGATGGCTACAAACTTCATGGCTGCACCATTAGACTTGCCCGGGTGGAAGTTGCTGTGGAGTCTCAGAGAAGACTGTGAAGAGGCCATCAGGAACTGGATGTTCTCCCAGAGTCCAGTCACCTATGCTTCTTTTATTTATTAAACTAGGTTTGTATTGTACATGAGGTACTTCATGTGATATGTTTTGGATTTAGTCATATTGGCTTTATTTCTAAGATATTCTATTGATTTAATGTGACCTGTTTGGTCTCATCAGAAGTCTTACCATTCGGCATTTGAACAGTGTGACAAGTGTCCCAATGGCCTTTATCAAAACCTGCTTAGGAAAATTAGTACTCTGATGAATTTGAATCCAAAATCCTTTTAACTATATGTTTTCAGCTACATGTTCCTTCCTAGTGGTCCCTATAACAGAGAGTGTATAATATCTTGTATTTTGTGGAAAAAGGAGATGGCACGGATTGGTTCAACATTTGGATACTTAGAGGATAAAGCTTCATGGT
>NM_152407.4
AGCAAGTGCGCGTGCGCTGCCTCTCAGCCCAAATTGGAAACATGGCCGTACGGTCGCTGTGGGCGGGCCGGCTGCGGGTGCAGCGCCTACTGGCCTGGAGTGCCGCGTGGGAGAGCAAGGGATGGCCGCTTCCATTCAGCACTGCCACCCAGAGAACTGCTGGTGAGGACTGCCGTTCTGAGGACCCTCCTGATGAGCTTGGGCCCCCTCTTGCTGAACGAGCCTTAAGGGTAAAAGCTGTTAAACTGGAGAAAGAAGTCCAAGATTTAACAGTGAGATACCAGAGAGCTATAGCTGATTGTGAAAACATAAGGAGGCGAACCCAGAGATGTGTGGAAGACGCCAAGATATTTGGAATCCAGAGTTTCTGTAAGGACTTGGTGGAGGTGGCTGACATTTTGGAGAAGACTACAGAGTGCATTTCTGAAGAATCGGAGCCTGAGGACCAAAAGCTCACTCTGGAGAAGGTCTTCCGAGGGTTGTTGCTTTTAGAAGCAAAGCTGAAAAGTGTGTTTGCCAAGCATGGCCTGGAGAAACTGACACCCATTGGTGACAAATATGACCCCCATGAGCATGAACTCATCTGTCATGTGCCAGCTGGTGTTGGGGTGCAGCCTGGCACCGTGGCATTAGTAAGACAAGATGGCTACAAACTTCATGGCCGCACCATTAGGCTTGCCCGAGTGGAAGTGGCAGTGGAGTCTCAGAGAAGACTGTGAAGAGGCCATCAGGAACTGGATGTTCTCCCAGAGCGCAGTCACCTATGTTTCTTTTATTTATTAAACTAGGTTTGTATTGTACATGAGGTACTTCATGTGATATGTTTTGGATTTAGTCATATTGGCTTTATTTCTAAGATATTCTATTGATTTAATGTGACCTGTTTGGTCTCATCAGAAGTCTTACCATTGGGCATTTGAACAGTGTGACAGGTGTTCCAATGGCCTTTATCAAAACATGTTTAGGAAAATTGGTACTGTGATAAATTTGAATCCAAAATCCTTTTAACTATGGGTTTTCAACTACATGTTTCTTCCTAGCGGTCTCTATAACAGGAATTGTGTAGTATCTTGTATTTTGTGGAAAAAGGAGATGGTAGGGATTGGTTCAACATTTGGGTACTTAGAGGATAAAGCTTCGTGGTCGTATAAATTTAGATCATTTGGATTGATTTTTATACACATAGATTTTCAGGACTTTACCttttgttttgtttttttccttttagccatcttttgttcttgtAATCCCAACTAGATAGGCTTTATGCTCACATCATTGTCCCATACCCACCCCTTTCTCATCCCCATTTGCAGGGGCTAAAGGTCTAGATGAGACTTGGAAGGCAAGGAGCATCGAAATTTGAGATACCCAGGACCCTTTCAAGCAAGAATGGCCAAAAAGCCTTGTGCTGTCTTTGCTCTTCAAATTATTTTCAGCCTCCTTGTCATATAATCATTTCAGGCAAACTGAGGCAACACTAACAGCTAATGACCCAGATGGCTCTATTTGGGTAATTTACCTACAACTTATTCCACCAGCCTTTACTCCTCTGCCCTTTTGTCAATTTTACCTTATAATCCTTTATTAAATGATGGGAGGTGGTGATCAGGACAAAAGTGTTAGGTTCCCATGATTTCTCATTTCATTTATTAATAGTTAATGCTGAATTTTTTTTTaagtttcctctggctctatttatgttactttttgcgataagaacacttaacataagtattctctcctcttggcaattttttttttttttcctgtgttgcccaggctgacctccaactcctgggcccaagcaatcctgcctcagcctgccaagtagctaggactacaggcgttcaccactgcgcccgCAAAGtttttttgttgtttttttttttAAGTTGGTACTCACAAATCACTACCTCTGTTATATTGACAAGCTCTATTTCCTATTCTTTGTATCTGTTAAGTCACATCTGTGTAAACATTGAGCTCACCTTTTATATATTAACCTCTAGAATTAATGGGCCTATGTGGTTTTTTTTCAGTCTTATAGCTGGTGTTCTGTAAAAGATTTGTCCAATAAACGACTTAATGAATGATACATCAGTCAGATTTTAGGAAGGCAGTCAATTATGGATATTTTAATGTTGGAAGAGGCCTTAATGATCAAATCTCACCCTTTCTGCTTCTGAAGTATGAAAATCTAGTCTTTTTAGGACTGGACACAAGGAAAATAATCTCTAAACTATTGACTAAATTCCAGTGAGAGTATGAATGAAGAACAACTAGATATTAATGTCAATCATTTAAGATTAATGGGCATGCAATTAAGTCTCCATTTAAGATTAATGGGCATGCAATGAAGTCTCCAGCAGACAATCAGATGTTGTTGGATGTCTAGATTATATAGGTTTAGGTTGAAGTTATAAAATAAAATAAAATTCATTTTCCACTGGAACTCTATGACATTCAGTGGAGTGGTGGAAAGTTAACCTCTTATACATTATAGATAATTCTAAGACAGCACACAAACTTATCAATAAAGCCATCTCCTTGTGGGCCTTACCATCTTCATCAGATTTAGACCCTTAAAAAACAAGTAAATATGCACTTTTAAAATGCAATCAAAAGACTGGTGGTTAAGCTTGTAAAACCAGAACATCTTTTGGCATTCCACTAAGTATATATTGTAAATTTAATGAACAATCAAGGTTCACAATAGGAAGTTGTCTTTTTTTGCCTTCCATTCTGTGAGATTTGACAGATGGTGACAATAAGAAAATGAGCTGATTGTAATTACTCTCTGTGTGTTTTTTTATTGCTAGCtatcattaccagttagaattaacattaattacaattaacaataaTTTTAGGTATGGAATGTTATGATTACCTAAAGAGATgtctctacctaatgagctcaagtgatcctcccacctcagcctaccaagtagccaggaccacaggcaagtgcaccaccatgactggctagttttgttttttggtttttggtttttggtttttggttttttttttttggttGGTTGGttgttttttacaggcggggtctcactatattgtccaggctagAAGAATTTTCTAATGGTCTATTACACCTCCCGTTTTGGCAAGTAAATTCAGAATAATTTTAGGTTCTTTTGTTATTCAGTAGTTTTGCAGACTTAAAAGTGTAAATTTAGAATTAGAAGATGAAGCTATAGTAGTAAGAATCTCAAGCTGAAGGGCTTTGGGGAGCCAAAGCAGCATATTAGAGCATaggcttgaacttaaatctcagctcagtcacctgcaggactttaggcaccagtgatttcacccttctgagcctgtttctttattcgtaaaatgattataataattctttcacagcgttgtgaggattaagtgaaatgtgttaaatgcctactacagtaggtgctcagatatttatttttattTTTTTATTATGCACATTGTTTTTCCTGCCTTTTTATGGCTGTCTAAAGTCTAGGGAAAAGGGAAGACTGGTTAATGATGAGTAGAAAAAACTTGTAAGCTAATCATTCACTGACTTATTTTCCTTCCATTTTCTGGTTTTTAAAATTAGCCACACCACAGGAAACCCACATTTTTAGATGGAAAGAGCAAGAAAATTGTGTCAGTGCTCTTAGTTATTTTCATCTTAATGGTATAGTGAAAAGACATTGACTTGAGATGATACTAAGGAAGCTTTGGCTCACTCTCACTTGAAGAGGGGATCTTGGTGTTGTAGTACTTGGACTGTACAAATGTTTTACTGACTTTTCTTACTGCTGTAAAGGAATCAGGCAGTTGGGTATTGATATGTTATTTGGTGCTCTCATTCATGGCAAAGGATTTGATAAATAAAAGTTCTTTAAACACTAAAGCAAAATCAAATGAGCAAAACTAAGGATGAAATGTAATATTCATCAGAACAAGGATCACTGAGAAAAAATATTCAGAAACAACTTTAATAAAACCTGAATTGAAATAACTGCA

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