Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name UFM1P3
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:100164724-100165518  UCSC
Coordinates (T2T) chr8:101289505-101290299  UCSC
Coordinates (hg19) chr8:101176952-101177746  UCSC
Strand -
Parental Sequence NM_016617.4
Parental seq. overlap 721 bp
Parental seq. overlap (%) 22.7%
Genomic Region Intragenic (SPAG1)
Retrocopy Summary UFM1P3, located on chr8:100164724-100165518, is a retrocopy of the parental gene UFM1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name UFM1
Full Name ubiquitin fold modifier 1
Also known as BM-002|C13orf20|HLD14
Coordinate chr13:38349851-38363619
Strand +
Gene summary UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M; MIM 603173) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Dec 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes UFM1P2
Bonobo Pan paniscus UFM1P2
Gorilla Gorilla gorilla UFM1P2
Orangutan Pongo abelii UFM1P3
Gibbon Nomascus leucogenys UFM1P1
Green monkey Chlorocebus sabaeus UFM1P1
Crab-eating macaque Macaca fascicularis UFM1P1
Rhesus Macaca mulatta UFM1P1
Baboon Papio anubis UFM1P1
Golden snub-nosed monkey Rhinopithecus roxellana UFM1P2
Marmoset Callithrix jacchus UFM1P4
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>UFM1P3
CCGCGGAGTTGGCGTGGGTTCTGGGTTCCTCCCGGCGCCACCATGTCAAAGGTTTCCTTTAAGATCACTCTGAGGTCTGACCCGCGGCTGGCGTACAAAGTACTCTGTTCCTGAAAGTACACCTTTCACAGCAGTCTTACAGTTTGCAACAGAAGAATTTCAAGTTCCTGCTGCAAGAAGTGCAATTATTACCAATGATGGAATAGGAAAAAATCCTGCACAGACCTGCTGGAAATGTTTTTCTAAAACATGGTTCAGAACTGCGAATTATTCCTAGAGTCGTGATGGAAGTTGTTAATATCGGCTGCTTGGAACATACAATTACCTTTCAGAATAAATATTGGTATTTTTTGTTGCTGTAAAATTGAAATCAGGCATTTAACACACTATGAAAACACCAAGAGTCAATGAATAATGAGACTCATCTGTCCCTGTTTGTTGTCTGTACTCTTCATGTGAAGAGGGAATTCATATGAATTAAGGGTAATAGTGTCACAGAAGATTGCTACCTCACACACAAACAGGTAGTTCATTTGGGGTGAATGGATTCTCCAACTATTTTATAACTGGGAGCTTCTGATAATTTTTTGGAAAACATTTGAAACATTAAAACTTACTGAATCTTACATATTTGTCTGAGTTAAAAATATAAAAAGAATTATGGATCATGGATGGTAATTTGCTTGATAGCATCTGGTTTGCAGACTCATAGTTTGATTTTTAATTAAATATATAGCTTATGATGAAGTCAATAAACATATCAATGAATAGTTAACTATATTAAATTTTTATCAg
>NM_016617.4
AGCACACTAGAGGAAGTCGTGCTACCCCCGCGGAGTTGTCGTGTGTTCTGGATTCATTCCGGCACCACCATGTCGAAGGTTTCCTTTAAGATCACGCTGACGTCGGACCCACGGCTGCCGTACAAAGTACTCAGTGTTCCTGAAAGTACACCTTTCACAGCAGTCTTAAAGTTTGCAGCAGAAGAATTTAAAGTTCCTGCTGCAACAAGTGCAATTATTACCAATGATGGAATAGGAATAAATCCTGCACAGACTGCTGGAAATGTTTTTCTAAAACATGGTTCAGAACTGCGGATTATTCCTAGAGATCGTGTTGGAAGTTGTTAATATCTGCTACTTGGAACATACGATTGCCTTTCAGAATAAATATTGGTATTTTTTGTTGTTGTAAAATTGAAATCAGGCATTTAACATACTATGAAAACACCAGGAGTCAATGATTAATGAAAGGTGACTCATCTGTCCCTTTTTGTTGTCCATACTCTTCCTATGAAGAGGGAATGCGTATGAATTAAGGCTACTACTGTCACAGAAGATCATAGTCTTTGATGCTACCTCACAACACAAACAGGTAGTTCGTTGGGGGCAAATGAATTAGCCAACTGTTAACTGGAAGCTTTTGATAATTTTTTTTTTTAGAACAATTTGGAACATTAAAATTTACTGAATCGTATATATTCATCTGAGATAAAAATATAAAAAGAATTATGGACCCTGGATGGCAATTTGCTTGATAGCATCTGATTTGCAGACTCATAATTTGATTTTTAATTAAATATATAGGTTGTGATGAAGTGAATAGACATATCAGTGAACAGTTAACTATATTAAATTTTTATCATTTACTTTTTTTAAGATTCAGACCTCAGTTATATAAATTTCAGTTTAATATCAACCAAAAAATTAAAATTTTAATCTAACCCTTATGTGTATAAATTGGTGTCCCATACCAGCTTTTAATGGTGGACCTATAGAATCCAGTACTTTTAATGGTGGGAATTTACAGTAGAAGCATCCTTTGCTGAGTTATACATTCCTTTATCAATCTCTTTTGATACAACATTTAAAACAAGTAGCTTCAAGAAACCACTGGTGTTTTGAGGATAGTATTTCTAAATAGCATTCAGGAACAGAGTATTATTGCACAGATCTGAAGATCAAAAAAAAGCTCAAGGAAATACAGATCGGAAGTGCTGATGAGTTATATTTATTGAAAACCCAACTTTTAAGGAAGTGCTAAGATCAGTCACCCATGTGAATAAGAAGCCAGGAAAGGAAAGATGGGGAAGCCCAGATCACCAGGCTTCTATTAAGGAGGAAAGCAACAGAGGAAACAGTGAAGGGGAACAGAAGGGGGTAGCAAAGTGTTACAGAAAAGCGGACTGGATAGACAAAACTGCAGAAGGTGTATGTTGGGGAGAACTGAAAGGGAAAACAAAATACTTGACATAGTCTTAAGTAGAAGAAGGCAGTTAGAGAAAACAAAGTATCTACTGGCCTTGTCAACATACAGACTTCAAAATACCCCTTATGAGAATCCAAAGAATGATGTGTGTAAGGGAAGATTTTATTTGCCCTTCCGGAAGAAATCAGTATCTATGCAAATCTTGAAAGACGAAATCAAAGCCCATTAATGATTCAGAATCAGTGCTTGACCTCCTGTATTCTGAATGGTGAACTCTGGAAGCAGGGATTGTGTCTGGCTCTTTTTAGAGCTGGAAATGTAGTGGCTTTCATTAAATACTTGCTGTAAAGTCTTTCTAAGACCAATTATTATCTTAGCATGTTTCAGTATCTTCTCTATCATAGGCCCTAAGTTCATTGGGGGAAAAAAAATAAGAAGATTCAACAGAATCAGCATTTGAAGTGTACCATTGGTAGTTGTTTATGAAATTACCAGATATTCATAAATGTGACAAATGAACAGCAGGATTATGAATTATCAAAGGAAAAAGTATTTGCTGAGGTGAAAAAATCTGATGTTTGAGGAAGtttttatttttatttatttgttttgtttttttttttttGAGGCAGACTCTCTGTCGCCAGGCttctcctgcctcagcctcacgagtagctgggactacaggcatgcaccaccacgcccagctaatttttgtatttttagcagagacagggAGGAAGTTTTTATTTTTATAAACAAAATCTGATGTTCAGAGGCCCCGTTTCTTACAATAAATGTTGAGTCTTAGTTAAGCAGGAATTTATGAACACCCATTTCCTGACTTTTTGCTTTAATTTAGATTTTTCTCCATCCTGTTTCTAGCACAAAAATTTGCCTGCTGTGTTACAAAAATAAATTTATGTTGTCCTGTGCCATAAAGTGATATATTTAATATTTTTATTCTTTGGTTTTGAACATTGTAAGTTCCTAAAAACATTTTATTAAACAAGTAGACATTTTGTTATTAAAAAAATGTGATCTGTAATTTCTTTGTGCAGAATGATTTGAAGTATTGTATTCAGTTTACATGCGTTATTGGTTTATAATTAATATCTAATGAAAATACATGTTGTTATATTGTAAACCATATTGTCTGTTCTTATTATTAGAGCTCTTAATCAGCACACCTTTTGAGTCAGTATATAATACATGTAGTAAAGAAAAAAAGGGCAAAGATGATTAATGACCATAAGTCAGAGAAATTAGTTTATagtcatctgccacagacatagtagtgatgtttcgtccaacaacagaccgcatatatgaccgtggtcccatattactatatttttactgtgctttatctatgtttggatacacaagtacttaccatcattttacagttgtttacagtattaggtacagtaacatgctctacaggtttgtagcctaggagcaataggccataccaaatagcctaagtttgtagtaggtgacatcaactaggtttgtacaagtacattctgatgttcacatagtgacaaaattgcctaaggaagcatttctcagaatttgttcctgtgattcagtgatacataacAGTACTTGCAAATGCCTGTCCATTTTACAGACGGaaaaaaaaaaaaaaaaaGTTGAGAAGAAAATGGGGTTATTGTAACTGGCTAGGTTGGTAggttccaaacctgggtgataacagagtcgcctaggaaattaaaaatacagatttttggaaacca

Publications

PMID - Link Title