Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NDUFA5P2
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:104566073-104566984  UCSC
Coordinates (T2T) chr8:105693518-105694429  UCSC
Coordinates (hg19) chr8:105578301-105579212  UCSC
Strand +
Parental Sequence NM_005000.5
Parental seq. overlap 804 bp
Parental seq. overlap (%) 14.6%
Genomic Region Intragenic (LRP12)
Retrocopy Summary NDUFA5P2, located on chr8:104566073-104566984, is a retrocopy of the parental gene NDUFA5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NDUFA5
Full Name NADH:ubiquinone oxidoreductase subunit A5
Also known as B13|CI-13KD-B|CI-13kB|NUFM|UQOR13
Coordinate chr7:123536997-123601611
Strand -
Gene summary This nuclear gene encodes a conserved protein that comprises the B13 subunit of complex I of the mitochondrial respiratory chain. The encoded protein localizes to the inner mitochondrial membrane, where it is thought to aid in the transfer of electrons from NADH to ubiquinone. Alternative splicing results in multiple transcript variants. There are numerous pseudogenes of this gene on chromosomes 1, 3, 6, 8, 9, 11, 12, and 16. [provided by RefSeq, Apr 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NDUFA5P5
Bonobo Pan paniscus NDUFA5P5
Gorilla Gorilla gorilla NDUFA5P5
Orangutan Pongo abelii NDUFA5P6
Gibbon Nomascus leucogenys NDUFA5P9
Green monkey Chlorocebus sabaeus NDUFA5P2
Golden snub-nosed monkey Rhinopithecus roxellana NDUFA5P5
Marmoset Callithrix jacchus NDUFA5P11
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NDUFA5P2
TGTTGGCACTGTCATAGTGGGTGTGCTGAAGACCACTGGCCTTGTGGGATTGGCTATATGCAAGAGTCCATAAGAGAGGCTGAGAATATTGTACACAAAGATTCTTGATGTTCTTGAGCAAATCCCTGAAAATGCAGCACATAGAAAGTATACAGAACAGATTACAAATGAGAAGCTGGCTATAGTTAAAGTAGAACCAGATGTTAAAAAATTAGGAGACCAACATTAAGGTGATCAAGTAGAAGAGGTGATTCCTCAGGTTGAAGATTAACTAAGTCTGGTGAGGAAAATGACGCAGTGAAAACCATGGGAGCCTTAGGGGAAGAGCCTCCTGCCAATCAGTGGAAATGGCCAATACAATTACTAAATGCCTTTGGTGGGTTGATAGGAAATTGATTTAATATTCTGTTATATTAAGAGTGTGTCCATACTATTGACATTTTATAATCAAGAGAAGTGATATACAAAATATTTAGGAGACTTTTAAAAATTAGTGATTATGGTAATATGGTCTTGTGAATCAACTTGTGATTTGTAAAGTACTCACACAAATTATTTCAAAGATGTTATTTCTTTGAACAGAGAGGTTGTGGGAAGATCTGACAATTAGAAAAATTCCTACAGCTCTTTAATGCAGAGGCCATAATCAAAAAGTAGAGTTTCCTTAGTAGTATCTTCAATACGTTATTTAATTTTTTATTGTCCCAAAGAAGAAAAGGCCCTTAATTATTATTGTTTAAACAAAGTTATAGATCACTGTTTGATGTAAATAATAAGAGTGAATATTTTCAAATATAAAATAGCACAAGCGGCTGGTGATAAAATGTGAAATTATGGGTAACCTCCTTGGCTGTGATCTTATGTATGTAAAGCAAAATGTAAATATATAATTATATACTGATTACAAAATCC
>NM_005000.5
GTCACCGAGTCGTTGGCGCTGTCATGGCGGGTGTGCTGAAGAAGACCACTGGCCTTGTGGGATTGGCTGTGTGCAATACTCCTCACGAGAGGCTAAGAATATTGTACACAAAGATTCTTGATGTTCTTGAGGAAATCCCTAAAAATGCAGCATATAGAAAGTATACAGAACAGATTACAAATGAGAAGCTGGCTATGGTTAAAGCGGAACCAGATGTTAAAAAATTAGAAGACCAACTTCAAGGCGGTCAATTAGAAGAGGTGATTCTTCAGGCTGAACATGAACTAAATCTGGCAAGAAAAATGAGGGAATGGAAACTATGGGAGCCATTAGTGGAAGAGCCTCCTGCCGATCAGTGGAAATGGCCAATATAATTATTAAGTGACTTTGGTGTGTTCATGGGAAACTGATGTAATTAAATATTCTGTTATATTAAGAGCGTGTTCTTATTACTGACATTTTGTAATCAAGAAAAGTGATATAGAAAATATGTAGGAGACTGTTAAAATTGGTGATTATGGTAATATGGTCATGTGAATCAATTTTTGATTTATAAAGTACTCACACAAGTTGTTTCAAAGATGATATTTCTGTGAACAGAGAGGCCATGGGAAGATTTGAAAATTATTAAAGAAAAATTCCTACAGATTTTCAATGCAGAGACCATAATCAAAAAGTAAACTTTCTTTAGTAGTATGTTCAATACATCATTTAATTTTTTAAGTTATCCTGAAGAAGGAAAGGTCCTTAATTATTATAGTCTAAACAAATTTATAGATTACTGTTTGAAGTAAATAATACGAGTGAATATTTTCAAATGTGATAAAATAGCACAAGTGGCTGGTGATAAAATTTGAAATTATGGTTAACCTCAGCTGTGATCTTATGTATGTAAAGTGAAATTTAAATAGATAATTATAGGTTGATTACAAAATCCATAGTGTCattttattttagtcattattgaattataccatttactctgttttcttatagtcttaattttattatattttgttgttactgtattatatttGAAAACCTTCAAATTAGAATACATTGTACAGTTAAAGAAATTGACTTGGTACTTAAAAGAAAGATTTCCCATTGCATACAGGTTATTGGAGAAATTTTCCTTTTGTTGCATTTGTGGAAGTTAGTTTTCTGGCCCGTGGCCTTTAATTTTCTTAATCAACCTAATTACATCAGGATAGAGGTAGAGTTTCTGTAAAAGAAGAGACATTAAGAGTTCCTGAAATTTATATCTGGCATACGGATAGGCTTATATTCAAAACATCTTAGTCATACGACCATAAATTAAAAGTGGAGTCACTAAATAGTTTGCAGTACGTTTCTAATATAAGTGTAGGTGGGTATCAAAACAAGACAAATGCTGTTCAGGGAAAGAAGTTGGCAAGCTTAAGGTTAAACAAAAATAAAATTACATGTGTTTTCGCCTTCCTAGCTCCCTGTCATTCCTAAATACTTGGTTAAATTTAACGTGGTATCTCTTTCCTTCATAGATAGTACTATACTCTTGTGGGGTTTTGTGTATACgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgCACGCGCATGCGCACATTTGCTCAGAATGAGAAAAAAATGGTATTTTTCCTTCTTTCCAGTATATTTCTCCCCTCATAGAGCTGTAACATGAATACTAAATAAATATTAAATAAGGTGGATTCTTAGAGGTTAGAGTGCAAGAAGGCTCCTTCTGGTGGGGAAGTGTTAGAGGgggagttagaagcccagggtttctcattctcatggttctagtgttgttaactcaatgactacattgaggcaagtttggcctgtttctcagaatggcctatttctaatgctgcaaaagaaatagaatatgatttataacaacattttcagttctaaacatttcttgaatatataatATATTTATTAAAACATGATGCTGAAGTGTGTTTGCATGGGTACTTTCAAGGTAATTTTCTAGCCAACCATTATTTTTCAGGTCCTTTGGACAACACAGAAACAAAGATGGCTTGCTGTGTTTTTGTCATATTTTCAGTCCCGTATCTGCCATGATTCTTGGGCATCTTTTATGTTTCACCAACAGTGTTACTGAACTTTTTTGCTAAAAGGGGACCTTACTGGTGTTTGCATTAGAAATGCTAGTTGCAGAATAATAGTCATTGTAAAAATAATATTATAACaataatagctaatgtttgttgagactttaatatgaatgtcaggcactatcataagtacctgactaatttcactcattaaacctgcactacaaccctaagagtgatactacaaattatcttcattttccagataagaaaCCAGAACCCTACGTGAGTAGTTTTCCCCTGCAATTATGCAACTTGGGGCCTtggggacactgaaaccaagagatgatttaataacaaatccaaggtcacatagctagtaagatgtgaagctgaagtttgaacccaggcagtctggttctagaactgatgctcctGTTATATTATTATTTATGAATATGCTTGGGATGTTGTGACTTCTTCCTGTGCTGTATGGGCTGTACCAAATGAAACTAGATCCTGCTCTCTTTACCTTTTCTGTCAAAATTATCTGTAAAGAACAAATATGAGCAGAAGTAGTAAACGATTTCATTTTCTGCAAAGAGCTGCATATAGGTTATAGGCAGATTATGTTAATGGGATAGGTATCTAAAAGGTATTGCAATTTGGTCATTGGTTCTTTCTCCTGTCTCAATTGCTCACAGAACTTTACACCTGATCGTTTTTACTCCTTCAGTCTTTTCCCAGTTGCTTCCTATAAACATCCAGGTTAAGTCTCCTGATCACTTTGCAAATGATTCTTTTATTCAGAGATCTTCAGTGTTTTGAGTGGCTACTAAACTAATTTTAATAATTTTCAGAATGGCCTATTTCAGTTCTCCCATGGGTTTCATTCTAGTTAATCATCATACTGCAGATACTTCAAAAGAAAGAGAAGCTAATCAATTTGAGCTTTGCTAAGAAAGAAGAAATGGCAACAAAGTTGATGCCCCCTTTCTCCCACACTGGGACTTAGTGCAGACGATTCCAATTTCTTGGCATTCTTTCCTTTGGGATGAAAATGGCTTATATTTAGGATAACTATAGGATAATTTATCATTCCACTTGGAATGATTTTGAGTGAAaataattacataaggataacagatgtacaccatgactgtcctgggcaaacaagatataggggggcaccctaCTGGAGTAAGGCTCAGGTCTCAAGGTTGCCATCTTTCCCACACCAGTAGGATCAACTAGTCTGTCATTGGAATAGAATGAATTGATGCCAGCAGTAGTAGTCATCATGTGCAATCAGGCCTCAAGTTTTATTGTATCCTTTCACTCTCCCTCATTCTCCCCTCCCCCTCCTTTTCCCTCAGAATTGGGGGATGGAAGAAAAGAGAGCTTATATTTTATTGTCAATTTTCTAATCACATTCAGAGGAGCGAAGCTAATTAAGCCAATAACAATGTTTATGAATGTATCTTTTTTAAAAGGGAGATGACAATATATAGGAAAATTCCCACATGTAGGCTAATAGCAGCTTTTTCTTTTTCCTCCCATCCTCTATGATTATGTAAACATACAGAAGTCTAACACCCTACACAAGTGTATTGTGGGGTATGGGATTAAGTACCAAATTGCTGAACATATCACTAGTATTTTGGATTTGCTGAGTGCAGTCTTCCCATTAAAACTAAGTGTTCAGTAGGGAggcgtggtggctcacacctataatcccactactttgggaggccgaggtgggtggatcacttgaggtcaaaagttcgaggccagcctggccaatatggtgaaaccccgtctctactaaaaacaaaaaCAAAAACTAAGTGTTCAGTGAGATTGTAGCCTATGCTACAACAATAGTAATGCCAATTGTTTTAGAGAAAAGTAAATGAGAGGCTACCAGTTGTGTTTAGAGGAGGTCGACGTTTTATTTTAGACAAAATTCACAGGAAATCACAGTGGGAATGTGATAAGGGGTTTGAATGATTGATGGGGACAGGAAGAATTCATTTGAGAGACTAGAGATGAGTCAGTATTCTAGATCGTGAAGTAAAATAGTGAGTCATGTAGTGACTTAGCATGGGTTATCCTTAAATCCCAGTGTCTTaagtgtattttttattcatactgcatgtctaaggagggttggcaaggagtgctcatagacccacaaggaatccaggctgagtgtggcaccatcaacatatatttccatgaccatagtggtggtggggaattggaacatggtaaattacacataggAATAAAAAAAAAGAAACAACCAAGGTTAAATTTTTTTTTGACTGTGCCACAAAATTTATGAATTGAACTTGCCATGCATCACTAATAATTTTCAAATTGGTCTTTAGGTTTACATTAGCAGCTAATTTTTTGTGGTACACTTAAATGTAATTTATGATTGGCATCTGTATATAATTAAATGAAAAGCATTGCAAAGATTTCTATTTTGGTATTTCTCATGATCTTCAATTTTTTTTTAGGTGAATCTATTAGGTTTTCTAAAGATAACTATTTTTTTTTTTTTACAAAATATTGGCATTTTAATCTCTCTATAACTGGAGGGTGAATTATTTTTCACCAGAGTAAAAcaggtccaaagtcccttatctaaattcctaatttcaaaaatctctgaaaacaaagttttttcataactcatttggcaacaaaccccacctgaattacatgaggctatttgtggtatttatcgcacttcaatgtgaatatgaatatattttgccacagatgtatcaatatatttgattctaaactgcttcctcagaccctcttaatgtgttacataatgtaaagtatatgcccatatttcctttcaaaaatctgaaaaattgtgaatatcaaacacatctgtcttaaaaggtttcagaaaagggacaatagacctATATTTCCATTCTCTTAACAAGTTCACAAAGTGGTATTATGATCCAAATTTAATCTAAATAATTTCCAAAACAAAAATTTTCAGGTCCTTAGTTTTCTAAATTATTTTAATATTAAAAATATTCATTATTCATTTTAACCTGTAGTAACAACAGGAGATACTTTGAAATGCTTGATTTTATCAAGCCACTAGGTGGCATCTTTGTAAAAATAAAAGCACATCAAAAGAAATGTTTATTACATAAATAAATGCTGAGATGAATAAAGGTAGATGTTTCATGAGAAATACGAAGTCGTTTGGTGGAATAAATCCTGAGAAAATGCATAGATTTATCATGAAAAGGAAAATGGAAAATGGTATTGTAAAATTACTCTTTCACTTTTGGAATTGAGAAGCTTTTTCCTATTGGTTGTTTTCATTAAGTTTGAATATAAATTTATTATGTAACCAAA

Publications

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