Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZBED5P1
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:105264205-105264497  UCSC
Coordinates (T2T) chr8:106391685-106391977  UCSC
Coordinates (hg19) chr8:106276433-106276725  UCSC
Strand -
Parental Sequence NM_021211.4
Parental seq. overlap 254 bp
Parental seq. overlap (%) 9.3%
Genomic Region Intergenic
Retrocopy Summary ZBED5P1, located on chr8:105264205-105264497, is a retrocopy of the parental gene ZBED5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZBED5
Full Name zinc finger BED-type containing 5
Also known as Buster1
Coordinate chr11:10852706-10858053
Strand -
Gene summary This gene is unusual in that its coding sequence is mostly derived from Charlie-like DNA transposon; however, it does not appear to be an active DNA transposon as it is not flanked by terminal inverted repeats. The encoded protein is conserved among the mammalian Laurasiatheria branch. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ZBED5P1
Bonobo Pan paniscus ZBED5P1
Gorilla Gorilla gorilla ZBED5P1
Orangutan Pongo abelii ZBED5P1
Gibbon Nomascus leucogenys ZBED5P1
Green monkey Chlorocebus sabaeus LOC103240189P1
Golden snub-nosed monkey Rhinopithecus roxellana ZBED5P1
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ZBED5P1
GCCAGCAGTGAATCGGATCTCTATGGAGGCAGCAGAGGTGATATCCCTGAACAGAGAGCATCACTCTGTCCTTGAATCCTTTTTTCCTCTATTTTGTTTTTTATTATTCCCCCCCTCTTCCCTGCCTCCAGTCTATGATGACTGACTCTTGACCCTGTTCAGGCCTCGGTGAAGGCTTTTGGTTGCTCTCCTTCCCACCCCATCCCTTAATTTTATTCTTTTGAAGAGTCTGCATTTCAAGCTGCCAAGGTGAAGAGAGTGATTACAAAAGGGAGTCCTCCTCATTTCAGCTC
>NM_021211.4
AGACCGGCGACCGCGCCAGCCGCGAATCGGATCTCTATGGAGATGGCCTAGGCGATATCCCTGAGCTGAGAGCATCACCCTGTCCCCGAATCCTTCTTTCCTCTCTGTTTTGTTTTTCATTCCCCTCCCTCTCTCCCCTCCCCCTCCAGTCCACGACGACTGGCTGTTGACCCTGTTCAGGCCTCGGTGAAGGCTTTTGGTTACTCCCCTTCCCACCCCATCCCTTAATTTTATTCTTTTGAAGAGTGCATTTCAAGCTGCCAAGGTGGAGAGAGGGATTACAGAAAGGAGAACACCTTATTTCAGcttttatttttatgtgataatctacctttaagaaaaggtgtaccatacctgagagcaccaggaagtcgcatgagagatcacctgatacatgaacgtatgatgttccatctgcgcattgatgaataggcagcatttacaaattaactgatgtgttgctgtatatcatctctttgatgattgctcctcttctttgtatcctgtcttataatttcaacacatttgcgatactcaatgtctattctaaattaaccatgttttgtaccacaaactcattgcccatggatctgttgctgaaacaaggaagtcttaaacaagaagtggaatctttctgttatcagattgtgtctgaatcaaatgatcagaaggttggaatattacaaagtgaagataagcagttgcaaccttcagtttctaaaaaatcagaaggtgagctttccagggtcaaaTTTATATCCAATTCCAACAAAATAACATTTAGTAAAAAACCAAAaagaagaaaatatgatgaaagttatttgtcttttggatttacttacttcggaaatagagatgcacctcatgctcagtgtgtattatgtaagaaaattttatcaaatagctctttagcccctagtaagcttcgaagacatttggaaactaaacatgctgcatataaagacaaagacataagctttttcaagcaacatctcgattcacctgaaaataataaacccccaacacctaaaattgtgaatacagataatgaaagtgctacagaagcatcatacaatgtaagttaccatatagcgctgagtggagaggctcatactattggagaattgcttatcaaaccttgtgcaaaagatgtagtgatgcggatgtttgatgaacaatatagtaaaaaaatagatgcagtacagctatcaaacagtactgttgcacgtcgaattaaggatctagctgctgacattgaagaagagcttgtttgtagactgaaaatttgcgatgggttttcactgcaactagatgaatcagctgatgtttcaggacttgctgtgctgcttgtgtttgttcgttataggtttaataagtctattgaggaagacctactcctgtgtgaatctttgcaaagtaatgctaccggtgaagaaatattcaactgtatcaacagttttatgcagaaacatgaaattgaatgggaaaaatgtgttgatgtttgtagtgatgcttctagggcagtggatgggaaaattgccgaagctgtcaccttaataaaatatgtggctcccgaaagcaccagtagtcactgcctattatacagacatgcactggcagttaaaataatgcctacatctctaaaaaatgtgctagaccaggcagtacaaatcatcaattatattaaagctcgaccacatcaatccagactattaaaaattttatgtgaggaaatgggtgctcagcacacagcacttcttctaaatacagaggtgaggtggctttctcgaggtaaagttcttgtaagactttttgaacttcgtcgtgaacttttggttttcatggattctgcttttcgactatctgattgtttaacaaattcatcttggctgctaagacttgcatatcttgcagatatttttactaaattaaatgaagttaatttgtcaatgcaaggaaaaaatgtgaccgtttttacagtatttgataaaatgtcgtcattgttaagaaaattggaattttgggcctcatctgtagaagaagaaaactttgattgttttcctacactcagtgattttttgactgaaattaattctacagttgataaagatatttgcagtgccattgtgcagcacctaaggggtttgcgcgctactctgttaaaatactttcctgtaacaaatgacaataatgcttgggttagaaatccatttacagttactgttaaaccagcttcattagtagcacgggactatgagagcctgattgatttaacatctgattctcaagtgaagcaaaattttagtgaactttcactaaatgatttttggagtagcctaattcaggaatacccaagcattgcaaggcgtgcagtgcgtgtacttcttccttttgctacaatgcacctgtgtgaaacggggttttcatattacgctgcaacaaaaacaaaatataggaaaagacttgatgctgcacctcatatgcgaatccgacttagcaatattacacctaatattaagcggatatgtgataaaaagacacaaaaacactgttctcattaaaATTGGAGGAGTTTGCATGTCTCATGATAACCAAATGTAAGATGAAAATAAAAGATGATTTACTTCATCTCTGGTATTTGGGGGATTTAAATAAAATGATTCCATTTTTTTATACTATTTAGATTTTAAGAAGGCTAAAGAATCAAACGTTTTAAACA

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