Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NRBF2P4
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:107982973-107984766  UCSC
Coordinates (T2T) chr8:109111473-109113266  UCSC
Coordinates (hg19) chr8:108995201-108996994  UCSC
Strand +
Parental Sequence NM_030759.5
Parental seq. overlap 1729 bp
Parental seq. overlap (%) 95.3%
Genomic Region Intragenic (RSPO2)
Retrocopy Summary NRBF2P4, located on chr8:107982973-107984766, is a retrocopy of the parental gene NRBF2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NRBF2
Full Name nuclear receptor binding factor 2
Also known as COPR|COPR1|COPR2|NRBF-2
Coordinate chr10:63133325-63155029
Strand +
Gene summary Involved in autophagy. Located in cytoplasm. Colocalizes with phosphatidylinositol 3-kinase complex, class III. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NRBF2P3
Bonobo Pan paniscus NRBF2P3
Gorilla Gorilla gorilla NRBF2P4
Orangutan Pongo abelii NRBF2P2
Gibbon Nomascus leucogenys NRBF2P4
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NRBF2P4
gGCTCCCTCAGCGCCTACGACTGGCTCCTGGGGTGCAGAGAGGGGCCACAGTCTCTGCGGCTGTGTCACGCTCCCCTGCAGTCCCCTCCATGTTCCCTGGCACCACTACTCCCCTTCCTAAGGCCGCCGCTTACCCCAGGGTCTATGGAAGTAATGAAGGACCCCTCAACCTGGCTCATCAACAGAGCAGATGAGCAGACCGTTTATTAGCTGTAGGCAAATACGAAGAGGCTATTTCTTGTCACAAAAAGGCTGCAGCGTATCTTTCTGAAGCTATGAAGCTGACACAGTCTGAGCAGGCTCATCTTTCACTGGAATTGCAAAGGGATAGCCATATGAAACAGCTCCTCCTCATCCAAGAGAGATGGAAAAGGGCCCAGGGTGAAGCAAGATTGAAAGCCCAGCAGAACACAGACAAGGATGTAGCTGCCCATCTTCAGGCATCTCACAAACCCTCTGTAGAGGATGCAGAGGGCCAGAGTCCCCTTTCTCAGAAGTACAGCCCTTCCACAGAGAAATGTCTGCCTGAGATTCAGGGGATCTTTGACAGGGATCCAGACACACTACTATATTTACTTCAGCAAAAGAGTGAGCCAGCAGAGCCATGTATTGGAAGTAAAGCCCCAAAAGACGATAAAACAATTATAGAGGAGCAGGCAACCAAAATTGCAGATTTGAAGAGGCATGTGGAATTCCTTGTGGCAGAGAATTAAAGATTAAGGGAAGAAAATAACAACTAAAGGCTGAAAAGGCCAGACTTCTAAAAGGTCCAATAGAAAAGGAGCTGGATGTAGATGCTGATTTTGTAGAAACATCAGAGTTATGGAGCTTGCCACCACATTCAGAAACTGCTACAGCCTCCTCAACCTGGCAGAAGTTTGCAGCAAATACTGGGAAAGCCAAGGACATTCCTGTCTTCCGCCCTTGGATTTTCCATCTACAGAACTTCCTCTTATGGAGCTCTCTGAGGATATTCTGAAAGGATTTATGAATAATTGAAATAGAAGGCCACCAAAAGGGGAAAAGAGGAAATAATACAGTAATCGTTAATCCAGCAAAAAGAAAAGGGAAAACCACATAGAAGGGTCATCCCGGAAATGCTTCATCTGGTGGACTGTGGGAGCAGAGGCATTGCCAGGACTTGGGAAACAGTCACTGTGAAATGCGCAGCATATCTCATTCACTCACTTGAGCTAATGATTCTGACTTGGCAGACGCTAAACTCATGGAGGTTCAGTTTCTCCTGATCCAAACCAAATGGCTACCTGGAATAATTTCTTCCAAGCAACAGTTATTTTTCTTATCTTCAGGTTTAAAATGTATAAAAGTTATGTGTAATTAATCTATAATGCCATAAATGATAATGCAAAACCTAAATAATATGGTGGCCGGAGGGGCTGCTTTATATTTGAAACATGCTTTCTATCATGCATTAACTGTATGCACTTTGTTAATGCACATTTTGTTTGTTTAAGGTAAGATCCACACCCTTCTAGATGAAACTATATGTGCCACACTTTGCACTACTCATAATGATAACCTCAAGACTATCAGAAGAAATATTTAAATTTCCATTTTATGAAGAAAGGAACCAAATTATTATGCTTTTTTAAACAAATTACCAGTTTACATAATTAATCAGGGTGCGTTTCAAGTTCTAACTTTGTTTATTGTATAATGCATCATTTGAAAATACCAAGGAGGAAATACCCTTTGTTTTTAATGATGCAAGAGTGGAAGTAATGCTAGTTGGTGGTATTTGATTGTAAGAAATCAATAAAGTAATTATGTTTT
>NM_030759.5
GCTCCTTCAGCGCCTATCGCTGGCTCTTGGGGCGCAGAGAGGGGCCGCAGTCTCCGCGGCTGCGTCGAGCTCCCTTGCAGTCCCCTCCATGTTCCCCGGCGCCACTACTCCCCTTCCTAAGGCCGCCGCTTACCCCGGGGTCTATGGAAGTAATGGAAGGACCCCTCAACCTGGCTCATCAACAGAGCAGACGAGCAGACCGTTTATTAGCTGCAGGCAAATACGAAGAGGCTATTTCTTGTCACAAAAAGGCTGCAGCATATCTTTCTGAAGCCATGAAGCTGACACAGTCAGAGCAGGCTCATCTTTCACTGGAATTGCAAAGGGATAGCCATATGAAACAGCTCCTCCTCATCCAAGAGAGATGGAAAAGGGCCCAGCGTGAAGAAAGATTGAAAGCCCAGCAGAACACAGACAAGGATGCAGCTGCCCATCTTCAGACATCTCACAAACCCTCTGCAGAGGATGCAGAGGGCCAGAGTCCCCTTTCTCAGAAGTACAGCCCTTCCACAGAGAAATGCCTGCCTGAGATTCAGGGGATCTTTGACAGGGATCCAGACACACTACTTTATTTACTTCAGCAAAAGAGTGAGCCAGCAGAGCCATGTATTGGAAGCAAAGCCCCAAAAGATGATAAAACAATTATAGAGGAGCAGGCAACCAAAATTGCAGATTTGAAGAGGCATGTGGAATTCCTTGTGGCTGAGAATGAAAGATTAAGGAAAGAAAATAAACAACTAAAGGCTGAAAAGGCCAGACTTCTAAAAGGTCCAATAGAAAAGGAGCTGGATGTAGATGCTGATTTTGTAGAAACGTCAGAGTTATGGAGCTTGCCACCACATGCAGAAACTGCTACAGCCTCCTCAACCTGGCAGAAGTTCGCAGCAAATACTGGGAAAGCCAAGGACATTCCAATCCCCAATCTTCCTCCCTTGGATTTTCCATCTCCAGAACTTCCTCTTATGGAGCTCTCTGAGGATATTCTGAAAGGATTTATGAATAATTAAAATGGAAGGCCACAGAAAAGGGGAAAAGAGGAAATAATACAGTAATCGTTAATCCAGCAAAAAGAAATGAAAAGGGAAAACCACATAGAAGGGTAATCCCGGAAATGCTTCATCTGGTGGACTGTGGGAGCAGAGGCATTGCCAGGACTTGGGAAACAGTCACTGTGAAATGCGCTGCGTATCTCATTCACTCACTTCAGCTAATGATTCCGACTTGGCAGACGCTAAACTCATGGAGGTTCGGTTTCTCCTGATACAAACCAAATGGCTACCTGGAAGAATTTCTTTCAAGCAACAGTTATTTTTCTTATCTTCAGGGTTAAAATGTATAAAAGTTATGTGTAATTAATCTATAATGCCATAAATGATAATGCAAAACCTAAATAATATGGTGGCCGGAGGGGCTGCCTTATATTTGAAACATGCTTTCTATCATGCATTGACTGTATGCATTTTGTTAATGCACATTCTGTTTGTTTAAGGTGTGTAAGATACACACCCTTCTAGATGAAACTATATGTGCCACACTTTGCACTACTCATAATGATAACCTCAAGACTATCAGAAGAAATATTTAAATTTCCATTTTATGAAGAAAGGAACCAAATTATTATGCTTTTTAAAACAAATTACCAGTTTACATAATTAATCAGGGTGCATTTTAAGTTCTAACTTCGTTTATTGTATAATGCATCATTTGAAAATACCAAGGAGGAAATACCCTTTGTTTTTAATGATGCAAGAGTGGACGTAATGCTAGTTGGCAGTATTTTATTGTAAGAAATCAATAAAGTAATTGTGTTTTA

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