Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SEPTIN8P1
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:13705280-13705802  UCSC
Coordinates (T2T) chr8:13971862-13972384  UCSC
Coordinates (hg19) chr8:13562789-13563311  UCSC
Strand +
Parental Sequence NM_001098813.2
Parental seq. overlap 459 bp
Parental seq. overlap (%) 10.4%
Genomic Region Intergenic
Retrocopy Summary SEPTIN8P1, located on chr8:13705280-13705802, is a retrocopy of the parental gene SEPTIN8. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SEPTIN8
Full Name septin 8
Also known as SEP2|SEPT8
Coordinate chr5:132750819-132778216
Strand -
Gene summary This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SEPT8P1
Bonobo Pan paniscus SEPTIN8P1
Gorilla Gorilla gorilla SEPTIN8P1
Orangutan Pongo abelii SEPT8P1
Gibbon Nomascus leucogenys SEPTIN8P1
Green monkey Chlorocebus sabaeus SEPT8P1
Rhesus Macaca mulatta SEPTIN8P1
Golden snub-nosed monkey Rhinopithecus roxellana SEPTIN8P1
Marmoset Callithrix jacchus SEPTIN8P1
Crab-eating macaque Macaca fascicularis Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SEPTIN8P1
CACAGAGCTGGAGCTGAAAGAGAAGGAAAGGGAGCTCCACGAGGAGTTTGAGCACCTGAAGCGGGTCCACCAGGAGGGAGAAGTGCAAGGTGGTGGAAAACCACTAGGAACTGGAGGAGGAGACCAATGCTTTCAGCTGACTGAAGGCCGCGGTAGAGGCATTGCAGTCGCAGGCTTTGCAGTTTCACCTTGCAGCAGCCCCTGTGGCAGGCAAGGACAAGAATCAACACATGTGCACTTACATGTCAAGAGTGGACTTTAGACTTTCATGTGTTCAGTTGCTTGAGTTACACCTTGTGACTCTTCTCTCATAACACGGTGTGAGGACAGACTGGGAGCTGGTACAGATTCCAGTGTTTAACAGCCTTGCTTTCCTCTACCCCACCCCAGGTCCAGGTTTCCCTGGGCCTGGCGGGTCACCCCCCTCTATGCAAACACATAAAAGCCATAAATGCTGGAATGCAAAACTGATGAGGTTTCTTCTTCAGAACCAGTGTTTGTTCTCCCATTTACAGTGTCACTA
>NM_001098813.2
ATCCTCTTTGCACAATGGTGGAACCATTAAGACGTTGTCCCAAGCCCTTGGGACAGGCAGGGTGATGGACACTTGCAATCTGACGCCTTGACCGTCGAGCTCCGCTTTTCTATTGCAGGAATCCCAGCCTAAACTGCGCATCCTGCTCGTTGGTTGCACAAGGAGCCGAAGGCTGGTCCCTTGCCCGGGAAGGCCGCCTGGCCGGACGCGCGGGTCCCGCCGGGGTTCCCGCCTTAGCTCCGGCCGGAGCATCAGGTGGGGCCCAAGACACCCGCAGACTAGGCTGCCGCGGCCTCTCCCGGATCCGACGGGTCTCCCGCAGCTTGTCCACACTCTGAATGCAGAGCCAGAGCCCCGGAGCCTCTCCCTGGGCGGCCATGTGGGTTTCGACAGCCTCCCCGACCAGCTGGTCAGCAAGTCGGTCACTCAGGGCTTCAGCTTCAACATCCTCTGTGTGGGGGAGACCGGCATTGGCAAATCCACACTGATGAACACACTCTTCAACACGACCTTCGAGACTGAGGAAGCCAGTCACCATGAGGCATGCGTGCGCCTGCGGCCCCAGACCTATGACCTCCAGGAGAGCAACGTGCAGCTCAAGCTGACCATTGTGGATGCCGTGGGCTTTGGGGATCAGATCAATAAGGATGAGAGTTACAGGCCCATAGTTGACTACATCGATGCGCAGTTTGAAAATTATCTGCAGGAGGAGCTGAAGATCCGCCGCTCGCTCTTCGACTACCATGACACAAGGATCCACGTTTGCCTCTACTTCATCACGCCCACAGGGCACTCCCTGAAGTCTCTAGATCTAGTGACCATGAAGAAACTAGACAGCAAGGTGAACATTATTCCCATCATCGCCAAGGCTGACACCATCTCCAAGAGCGAGCTCCACAAGTTCAAGATCAAGATCATGGGCGAGTTGGTCAGCAACGGGGTCCAGATCTACCAGTTCCCCACGGATGATGAGGCTGTTGCAGAGATTAACGCAGTCATGAATGCACATCTGCCCTTTGCCGTGGTGGGCAGCACCGAGGAGGTGAAGGTGGGGAACAAGCTGGTCCGAGCACGGCAGTACCCCTGGGGAGTGGTGCAGGTGGAGAATGAGAATCACTGCGACTTCGTGAAGCTGCGGGAGATGTTGATCCGGGTGAACATGGAAGACCTCCGCGAGCAGACCCACAGCCGGCACTACGAGCTCTACCGGCGCTGCAAGTTGGAGGAGATGGGCTTTCAGGACAGCGATGGTGACAGCCAGCCCTTCAGCCTACAAGAGACATACGAGGCCAAGAGGAAGGAGTTCCTAAGTGAGCTGCAGAGGAAGGAGGAAGAGATGAGGCAGATGTTTGTCAACAAAGTGAAGGAGACAGAGCTGGAGCTGAAGGAGAAGGAAAGGGAGCTCCATGAGAAGTTTGAGCACCTGAAGCGGGTCCACCAGGAGGAGAAGCGCAAGGTGGAGGAAAAGCGCCGGGAACTGGAGGAGGAGACCAACGCCTTCAATCGCCGGAAGGCTGCGGTGGAGGCCCTGCAGTCGCAGGCCTTGCACGCCACCTCGCAGCAGCCCCTGAGGAAGGACAAGGACAAGAAGAATTAACGCACGCACAGACTTACATGTCAAGAGTGGACTTTAGACTTTCATGTGTTAAGTTGCTTGAGTTACACCTTGTGACCCTTCTCCCATAACATGGTGTGAGGACGGACTGGGAGCCGGTACAGACTCCAGTGTTTACAGCCTTGCTTTCCTCCCACCGACCCTGGCCCCAGGCTGCCCCGGGCCTGGCGGGCCACCCCTCTCTATGCAAACACGTAAAAGCCATGAATGCTGGAATCCAAAACTGACGAGGTTTATTTTTTTCAGAGCCAGTGGCTGGTCTTCCATTTACAGTGTCACTATTCCCTGACGGAGCTGTTATGTGCCGCTCTAGCGAAGGCCCCAGCCGGGATGCTAGGCCTAATTGTTCAGCGTGGAGATGGCAACTCACGTGGTGCCCTAGGTGCAGCTGCGTGGTCTGGTATACATGCTGCAAAATTCACCCAGTTCCCCTCATTTTAATTTTTCTAACCTACAGCTTAATTTTAATAACTTTAAAACACTTCTAAATATTTATTTTGGCACCAGCGTCAAGACAAATAATATCCTCTCCCATTATTTTCATAAGTAACACAGATTCCCTGATTTTTAAAAACTAAAAATACAGCTAAACCTTTCTTATGTATAAAGTATGCCTATCATATACAGGGAGAGGTGGGTAATAAACTTCCTGTAATGACAGTGTTTGGCATTTCTTTATGGATGGAATTGGAACATGAACAAGACCATGTCCAGCGTTTTTACTGTGAATGTAAATGGAACAGCAGCCCAAAGCTGTTGTCTGTGCCCCAGAGGTGCTACCTGTAGACAGGGACCAACTCCATGTGTGTGTGTTAAGTGTTTGACTCCAATTAAGACTCCCAAGCAAATCCTGCATATTCCAAATGTAAAGAGTACTCAGTGGGAAAAAGGTTGTTACCTCAAAGTCATTGCTTCTTTCCTGGCTGGGTCACAGGGTGAAGAGATGAAGGTGTCTGATGTATATAGACAATTAGGGAAAAATGAGCGGCAAAGGAGCTTTCCCCTTCAGCTGCACTCTAAAGGGGAACATTTTAAGGAAGTACTAGCAGCTTTGACTCTTCTATGCTCCTGTTGGTTTACAAGCCACCAAGAATGTCAGTGTTGAGAATACGGCCTGGTAAAATGGGAGATGTAAAATGACTAAATGAAAGGAAGGGTAGTTTTAATGTTGAAGCACCgtgctgggcactggagctacccagaggaatgcacaacgctcccctcaaggagctcacagtctagCCTACTCCCTGGCTGGAAGCCTCAGGAAGACGTGCTAATTTATTGTGGAATTGGTAGTTTGCTTTTCATGCCCCTGTCTTCCTTCTCATGACCATTTCCCCCTTTCTGTCTGGCTTGCATTATTGATTTCCAGGACCAAGTCCTGGCTTCCTCCTGCCTTCCTGAGATGATGTTCTGCTCAGGGAGAAGTGGAGGGGTGAGCTGTGTGTGTCCACCGAGGCACGGCCAGGAAGAGGCAGCCTTTACCTGTGAGGGGCTCCATGCTCCAGCAGCAGAGCAGGTTCTAGTGACAATTCAACTTTTTATGCTATGACcaggggtggatctaaattttatggggctgaaagcttgaattatttagaaagacttctttaagaaaaacaatgttaatataaaattaggtacagggtcttggaaggggccctgaagattaagcttccttagcgtcacaataagtccgtatctgGTTGCAATTGAAAACTGATGCTTCAGTGAGGGTATCTAAAAAGGTAAACTGGCATATCCAGGGCAAATGTGGGCTGCCAATGGCTCATCTCTAGGGTAATTTTATGTCTGAAAGTGTATGCAGTTGGGTCAGAGCATGACCTTTAAGATAGCCTCTCTCAGCTAACATATTTATGAAGATGAGGCCTGGTGACCCAGCAGGTTCATTGGATACATAAGAAATGAGAATTCCTGGTTCATGGGCCAACCTAGGACTCTGGAGTATGCAGACTTGGCCATTCGTCCATTGTGGCCTGCGGGTCGCACCCCAGGCATACTGAAAGGCCATACTCGTGGCTGGCTGCCTGCGGGCCTAAGCCTTCCCAGGATCTTCAGGACACTTGACAGACTTGTGTTTTCTGGTCTGAGCTGCCTCCACAGGTCCCTCCAGCAAGCCTCACTGCACCTCTCCCCTGCTGTTTGTGTTTGGAATTTTGTCTTCTTTAGCTGAGACCAAATTAAACCTTGGTGCATAAAGTGAGCTTAAAACTTGCCACTGTTTAGTAAGTTAGCCCCCATAGAATGTGACCCTGTCTGCAGAGTCTCATTTACCCCTCTTTTTCTCATTGTCATTTGTTGGCTTTATTAGGGCTGTCTTACAGGATCATGTTGGCATTTACTATCATGTCTTTATCATAAACCATGTTTGTTTGAGGTAGAagaatcaccatataattcgttgcccaaattgggactattgagagagaaaggggatgctattaattacaccagatcaaaaggcataaaccagacctgtcccaggccgatgtggaaatatgttctttctaGTTGTGGGTACCCTGATCTAGGTGGTTTGTAATTGTGCATTACTGACTGCATATGTTTGTGTATGTGTAAATGTGGGCTCCCTGTTAAGTGGGGCTCATGGATACGAGGCCTGAGGAAGTGTGGCTTGCTAGTCTGTTACGTTAACATGCTTTTCTAAAATTGCTTCACGTGTTAATTCATTTACTCCTGCATTCATTGACTGTTTTTGTTCTTTTCCATTCACTTTGTACTTATTTTTTTCATTAAATTTTGCATTTATTTTGA

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