Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DNAJC8P3
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:141967418-141968810  UCSC
Coordinates (T2T) chr8:143104406-143105798  UCSC
Coordinates (hg19) chr8:143048779-143050171  UCSC
Strand -
Parental Sequence NM_014280.3_2
Parental seq. overlap 1229 bp
Parental seq. overlap (%) 69%
Genomic Region Intergenic
Retrocopy Summary DNAJC8P3, located on chr8:141967418-141968810, is a retrocopy of the parental gene DNAJC8. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DNAJC8
Full Name DnaJ heat shock protein family (Hsp40) member C8
Also known as HSPC331|SPF31
Coordinate chr1:28200278-28233029
Strand -
Gene summary Enables Hsp70 protein binding activity. Located in cytosol; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DNAJC8P2
Bonobo Pan paniscus DNAJC8P2
Gorilla Gorilla gorilla DNAJC8P2
Orangutan Pongo abelii DNAJC8P3
Gibbon Nomascus leucogenys DNAJC8P3
Green monkey Chlorocebus sabaeus DNAJC8P2
Crab-eating macaque Macaca fascicularis DNAJC8P6
Rhesus Macaca mulatta DNAJC8P6
Golden snub-nosed monkey Rhinopithecus roxellana DNAJC8P4
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DNAJC8P3
TGAGGTGAAACAAATAGAGAAGAGAGACTTGGTTCTAACATCCAAAAATCGGATTGGAAGGCCGAACGTCCTGGTTCCTCTTACTTCAATTTGAACCCGTCTGAGGTTCTTCAGATAGATCCTGAAGTTACAGATGAGAATATAAAAAAGAGGCTTTAGCAGTTATCCATATTGGTGCATCCTGACAAAATTCGAGATGATGCTAACAGCACAAACAGCTTTTGAAGCTGTGGACAAAGCTTGCAAGTTGCTACTGGATCAGGAGCAAAAGAAGAAGGTCCTGGATGTAATTCAGGCAGGAAAGGAATACGTGGAACGCAGTGTGAAAGAGTGAAAAAAACAATTAAAGAAGGAAGGAGAACCTACGAGTTTAGCAGAGGCTGATTCTGAGCTGTTCAAACAAGCTGTATGTATACAGACAATGAAACGCTTTGCTGAGCAGGAAATTAAAAGGAAAGAGAAAGAAGCCAAAGAGATGCATGAAAGGAAACGACAAAGGGAAGAAGACACTGAAGCTCAAGAAAAAGCCAAATGAGAAAGAAAGCGGCAGAAAAACTTTGAAGAAAGTCGTGATGGTCATGTGGACAGCTGGCGAAACTTCCAAGCCAATACAAAGGGGAAGAAAGAGAATAAAAACCAGACCTTCCTGAGACAACCAAAAGTAAAAATGGAGCCGTGTGAATGACCACCCAGGGTCACAGGCACAGAACCTTCGCCCTGCTGTCTCCCCTCCTGCTTTGAAGACTCATTCTTCCCTCCCACTTCCACCCCAACATAGAATAGTATTTGCTTTTTAGTCCTTTTTGTTTTCAATACAATCTAATATCGAACAGAGTAATTCTTTTGTGCACTGAGATGAGGGGCTTGGTTTAAACAAAAGACCTTTCCCTCTCCCTGCCCCGAGAACCTCCAGGATTAGAGGGTGCTGCCTCCTCTTCCCACAGCCTGTAACTTAATGTTCTTTTCTTCACTGAATTGTGATGGTTAGAAATTTCGTGGATAGCTGTGGAAATCATCCAATTAAACATATTGCTTAAAATGACATTGCTGTGACTTCAGAGACAAGCCTGGAAGGGGCACCTTAGGAAGCCGCTTTGCTTCAGTTACTCACCTGGGTGTTCCAGGTGAGACAGGGAACACTGTGAGCACACAGAGCAGGCACCTGCTGCCCTGATGCCCTGTGGTGTTCGGCACGTGCCCTCCCGTCTACTGACCAATCAGCATGGCATGAGGCCCATGCCGCCCAAACCTTTCACTTTCCAAAGAGCTAGTCATCCTCCACCTTGTACCATGGTGTCCTAGCCTGTCTGCATTTGTTAGTGGTAATATTCTTTATGTGTAATAATTTTTTATACCCT
>NM_014280.3_2
AGAAGGGTCACGTGGTGGCTGGGCCGGGGAAATGGCGGCTTCAGGAGAGAGCGGGACTTCAGGCGGCGGAGGCAGCACCGAGGAAGCATTTATGACCTTCTACAGTGAGGTGAAACAAATAGAGAAGAGAGACTCGGTTCTAACTTCGAAAAATCAGATTGAAAGACTGACCCGTCCTGGTTCCTCTTACTTCAATTTGAACCCATTTGAGGTTCTTCAGATAGATCCTGAAGTTACAGATGAAGAAATAAAAAAGAGGTTTCGGCAGTTATCCATCTTGGTGCATCCTGACAAAAATCAAGATGATGCTGACAGAGCACAAAAGGCTTTTGAAGCTGTGGACAAAGCTTACAAGTTGCTACTGGATCAGGAGCAAAAGAAGAGGGCCCTGGATGTAATTCAGGCAGGAAAAGAATACGTGGAACACACTGTGAAAGAGCGAAAAAAACAATTAAAGAAGGAAGGAAAACCTACAATTGTAGAGGAGGATGATCCTGAGCTGTTCAAACAAGCTGTATATAAACAGACAATGAAACTCTTTGCAGAGCTGGAAATTAAAAGGAAAGAGAGAGAAGCCAAAGAGATGCATGAAAGGAAACGACAAAGGGAAGAAGAGATTGAAGCTCAAGAAAAAGCCAAACGGGAAAGAGAGTGGCAGAAAAACTTTGAGGAAAGTCGAGATGGTCGTGTGGACAGCTGGCGAAACTTCCAAGCCAATACGAAGGGGAAGAAAGAGAAGAAAAATCGGACCTTCCTGAGACCACCGAAAGTAAAAATGGAGCAACGTGAGTGACCGCCCAAGGTCACAGGCACAGAACCTTTCCCCTGCTATCTCCCTTCCTGCTTCGAAGGACTCATTCTTTCCTCCCACTTCCACCCCAACATAGAGTAGTATTTGCTTTTTAGTCCATTTTGTTTTCAATACGATTTAATATCGATCAGAGTAATTCTTTTGTACATTGAAATGAGGGGCTTGGTTTAAAAAAAGACCTTTCCCTCTCCCTGCCCCTAGAACAACCAGTATTAGAAGGTGCCACCATTGGTGCTGCCTTCTCTTCCCACAGCCTGTAACTCAGTGTTTTGTACTTCACTGAATTGTGATGGTTAGAAACTTCGTGGATAGTTTGTGGAAATCATCCAATTAAACATACTGCTTAAAACAGTGTTGCTGTGACTTCAGAGACAAGCCTGGAAGGGGCACCTTAGGAAGCCCCTTCGCTTCAGTTGCTCGCTTCTGGGTGTGCTCCCTTCGAAGGCCCAGATAAGACAGGGAACACTTGTGAGCACACAGAGCAGCATCTGATGCCCTGTGGTGTTTGGCATGTGCCCCCTGTCTACTGACCAATCAGTGTGGCATGAGGCCCACGCCACCCAAACCTTTCACTTTCCAAAGAGCTAGCCGTCCTCCACCCAGTACCATGTCCTAGCCTGTCTGCATTTGTTAGTGGTAATATTCTTTATGTATAATAAATTTTTATACCCAAGCCATTGATGTACTTTTCCTTGTACTCTCCCTTGTGGGTCCCTTGTCTGGCTTGGCTGAACCCCAAAATGCTTTGGGGTTGGACAGacctggctgaaccttagtttcttcatctatgaaatgggaatatgaattactgcagcagcttttagggcagatttgccatggcatatacaaggtaactaccatagtgcTCCTTGGGTATTGCCAATATCCTATTATTTCTGtgtaaaatgaagatactgattgttttgaggattaaatgaagtaatatatgaaa

Publications

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