RCPedia: Rtcs

Summary

Retrocopy Name	CDC42P3	Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr8:142995827-142996742 UCSC
Coordinates (T2T)	chr8:144139804-144140719 UCSC
Coordinates (hg19)	chr8:144077244-144078159 UCSC
Strand	+
Parental Sequence	NM_001791.4
Parental seq. overlap	863 bp
Parental seq. overlap (%)	8.2%
Genomic Region	Intergenic
Retrocopy Summary	CDC42P3, located on chr8:142995827-142996742, is a retrocopy of the parental gene CDC42. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	CDC42
Full Name	cell division cycle 42
Also known as	CDC42Hs\|G25K\|TKS
Coordinate	chr1:22052709-22101360
Strand	+
Gene summary	The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	CDC42P5
Bonobo	Pan paniscus	CDC42P5
Orangutan	Pongo abelii	CDC42P5
Gibbon	Nomascus leucogenys	CDC42P4
Gorilla	Gorilla gorilla	Without Homology
Green monkey	Chlorocebus sabaeus	Without Homology
Crab-eating macaque	Macaca fascicularis	Without Homology
Rhesus	Macaca mulatta	Without Homology
Baboon	Papio anubis	Without Homology
Golden snub-nosed monkey	Rhinopithecus roxellana	Without Homology
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>CDC42P3
aGTGCTGCTAATGCCCCAGTGAAGAAGCTGAGGTCAACATCAGATTTGAAATATTTAAAGTGGATACAAACTTATTTCAGCAATGCAGACAATTAAGTGTGTTTTTGTGGGCAATGGTGCTGTTGGTAAAACATGTCTCCTGATATCCTACACAACAAACAAATTTCCATCAAAATATGTACCAACTGTTTTTGACAACTATGCAGTCACTGTTATGATTGGTGGAGAAACATATACTCTTGGACTTTTTGATACTGCAGGGCAAGACGATGATGACAGATTATGACCGCTGAGTTATCTACAAACAGATGTATTTCCAGTCTGTTTTTCAGTGGTCTCTCCATCTTCATTTGAAAATGTGAAAGGAAAGTGGGTGTCTAAGATAACTCACCACTGTCCAAAGACTCATTTCTTGCTTGTTGGGACCCTAATTCATCTCAGAGATGACCCCTCTACTATTGAGAAACTTGCCAAGAACAAACAGAAGCCCACCACTCCAGAGACTGCTGAAAAGCTGATCCGTGACCTGAAGGCTGTCAGGTATGTGGTGTGTTCTGCACTCACACAGAAAGGCCTAAGGAATGTATTTGATGAAGCAATATTGGCTTCCCTGGAGCCTCCAGAACTGAAGAAGAGCCACAGGTGTGTGCTGCTAGGAACATCTCTCCAGAGCCCTTTCTGCACAGCTGGTGTCAGCATCATACTAAAAGCAATGTTTAACTCAAACTAAAGATTAAAAATTAAAATTCGTTTTTGCAATAATGACAAATGTCCTGCACCTACCCACATGCACTCGTGTGAGACAAGGTCCATAGGTATGGCCCCCTCTTCCCCCTCCCAGTACTAGTTAATTTTGAGTAATTGCGTATTGTCAGAAAAGTGATTAGTACAAGTTTTTGTTTTGTTGCTTCAAAA

>NM_001791.4
GCAGTGCTGCCAACGCCCCGGTGGAGAAGCTGAGGTCATCATCAGATTTGAAATATTTAAAGTGGATACAAAACTATTTCAGCAATGCAGACAATTAAGTGTGTTGTTGTGGGCGATGGTGCTGTTGGTAAAACATGTCTCCTGATATCCTACACAACAAACAAATTTCCATCGGAATATGTACCGACTGTTTTTGACAACTATGCAGTCACAGTTATGATTGGTGGAGAACCATATACTCTTGGACTTTTTGATACTGCAGGGCAAGAGGATTATGACAGATTACGACCGCTGAGTTATCCACAAACAGATGTATTTCTAGTCTGTTTTTCAGTGGTCTCTCCATCTTCATTTGAAAACGTGAAAGAAAAGTGGGTGCCTGAGATAACTCACCACTGTCCAAAGACTCCTTTCTTGCTTGTTGGGACTCAAATTGATCTCAGAGATGACCCCTCTACTATTGAGAAACTTGCCAAGAACAAACAGAAGCCTATCACTCCAGAGACTGCTGAAAAGCTGGCCCGTGACCTGAAGGCTGTCAAGTATGTGGAGTGTTCTGCACTTACACAGAAAGGCCTAAAGAATGTATTTGACGAAGCAATATTGGCTGCCCTGGAGCCTCCAGAACCGAAGAAGAGCCGCAGGTGTGTGCTGCTATGAACATCTCTCCAGAGCCCTTTCTGCACAGCTGGTGTCGGCATCATACTAAAAGCAATGTTTAAATCAAACTAAAGATTAAAAATTAAAATTCGTTTTTGCAATAATGACAAATGCCCTGCACCTACCCACATGCACTCGTGTGAGACAAGGCCCATAGGTATGGCCCCCCCCTTCCCCCTCCCAGTACTAGTTAATTTTGAGTAATTGTATTGTCAGAAAAGTGATTAGTACTATTTTTTTTTGTTGTTTCAAAAAAAAAAtttttgtgtgtgtgtgttttttttttttttttttttgttgtttAAAAGCAAGGCATGCTTGTGGATGACTCTGTAACAGACTAATTGGAATTGTTGAAGCTGCTCCCTGGTTCCACTCTGGAGAGTAATCTGGGACATCTTAGTGTTTTGTTTTGTTTTTTTCCCTCCTCTTTTTTTTGGGGGGGAGTGTGTGTGGGGTTTGTTTTTTAGTCTTGTTTTTTTAATTCATTAACCAGTGGTTAGCCCTTAAGGGGAGGAGGACGGATTGATTCCACATTCCACTTCCTAGATCTAGTTTAGAAAACATGTTCCCCATCTGGTGCTCTTAGGAAGGAGTATAGTAAATGCCTCATTTAATAACATACTCCTTTTTGAAAGTTGCCTTTTCTCTCCACCCTTGAGTAGATCCAGTATTTGATGAAACTCATGAAAGTGGGTGGAGCCCATCTTGCCCCTCCTCTTTTCTAGGACGCACTATATGTGACTGTGACTTTCAAGGACATTTGTTTGCCATTTGCTGATTTTTTTGGGAAGTTAATTTCTAACTTCTTTCACTGATAAATGAAGAAAAGTATTGCACCTTTGAAATGCACCAAATGAATTGAGTTTGTAATTAAAAAAATTTTTTTCCCTTTCAGTCATTGTCTTATATGCTTAGCATAGATTTGCAGCTCAGTAGTATATGGTGTTCCTAGAATGCAGCTGAAGACCTGTTATGTAGAGGAAATACGAGGGGTGGTGCTAGAAGACAGACATCTGTGGAATGATTCACATCCTCTCAAGTTAGGAGGATGGAGGCCTGCTTCATTAAGAAGCTGGGGGTAGGGTGGGGGTGGGGAGAACACTTAACAACATGGGGACCAGTCAGGGGAATCCCCTTATTTCTGTTTTGCATATGAGGAACCCTAGAGCAGCCAGGTGAGGCTCTCTAGTTTAATAAAAATCATGGAAAGACTCTTAATGCAGACTCTTCTTAAGTGTTAATAGGGATTTTTTCAGCTTATTTTGGTTGCAGTTTCCAATTTTTAAAAATGTTGAGGTAATCTTTCCCACCTTCCCAAACCTAATTCTTGTAGATGCATTAGTGTTGAACCAATGCTTTCTCATGTCTCAATTCTTTGTATATGCATTCTTTTCAGATGTATTAAACAAACAAAAACCCTTCACAAGCCAGCCTGAGGGTTGTTATTTTCCCTCCGTCTCTTACTTTTCAGATATTGAGGAGTGGGAATTTGACTCTTGATAACATCAATTTCTAACAAACTTTGGGATAAAATTTTAAAGCTTTATTATTTTTATTTTCTGGCATTTTAGTTTGAGATAATATTTAGCCCTCTATATGTTCAGGTTTGTGCTTTCTCCTCTAAGTTTGACCCTTCCCTTAAATACCAAGTAGGTCCATAATAATTCTTAGTGAAGCAGTGTTCAGGAAGCTCACTGCTCATGGTGGAAGGAAATGTCAGTGTACCTTTAATCCATAGATCATTGAAAAGCAGCTCATTTTCCCCCAAGTTTTCTGCATCAGTGGTTCTCCAActggagtgcagcttgaacaatgtgatttttaagttttccaggcatttctaaaatgtagccaagtttgggaatcacCACACCTAGTTGGTTATCTCAAACTACTACTATCAGAATACAGGTTCTGTGCTGCGAATCTGAATATGGGATACATTTTCTTTAGGTAGCAAGAAAGGTTTATTTACCTTTAGGACATTATACTGATCTGCATGAGAATCTTAGAAACTAAGAACCCTTAAAATCAGTTAAGGTTGGTACACTGTGGCCTCATTTTGATAGTTCTCTGCATGGAGTCATGTTTGGCATGATTTGCATACTGTGCTAGAATTAAGCTGGGTTGGTTGAGAAGGGGTTAGGAAGAGGCAGATGTAAGCTTTAACAGTTCTAACCAAGAAATGCATCTTATTTATTCCTTGTTGACTATACTAGGGAGAGATACCTGGATCATGTGATACCCTGGAAAGCAGGGACATATGTATCCTTAGTGTAGTCAGGGGCGTATAGGTCCTTGACTATTGCTATATCTTTGTCCTAAAGCAATGCTTGACATGATATGGCTCTAGAAGTAGTCATTGGATGGGTATATTATTTTATAAATGAGTAAGTGAAATAAAGCAGGTCATACAGTTGTGTCAACGAATTATCCGTGTATCAGAAGAACAAGGATGATGGGGATTGATTGAAGCTAATGTTTTCTTAAATATTTTCAGATTGATTTCTGCATGTCAGAAGAACTTGGGTAGCAAGTGGATGCAGCTTAGGTTTTCCATTTAAATATTGTTTTCTATTTGACGTAACAAACTTGCTTATAGTCGTGGCTTAGAAGGTGAGTGATATTCTCCAGGGAGTATGATTTAGAGGCTGGAAAGGGTTATTGAAAATAGTCCTTACAGGCTTAGTTTGTGTCAGAATTTATAGTATTTAATACGATGTTAATATATTATTGCTATTTATAAGTGTTTTACTGAACATCCTAGAAATAGAtttttttttttttttttttttgagacggagtctcgctctgtcgcccaggctggagtgcagtggcgcgatctcggctcactgcaagctccgcctcccgggttcacgccattctcctgcctcagcctcccgagtagctgggactaccggcgcccgctaccacgcccggctaattttttgtatttttagtagagacggggtttcaccgtgttagccagaatggtctcgatctcctgacctcgtgatccgcccgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcgcccggccAGAAATAGATTTTATAGTTAAAGCGATGTTCTTCAAGCTGGACTTTATGCCACAAGGGGAGTGTATTCTAAAGGGGAAGAAAAGGATTGTGGTTTAAAAGAACAATTGTAATATTTCCTTCATTCTGAGGTGTATTTTTCTCACATTTTCATATTGTAATTAGGATACCTGTTAACATTGGTGTACATTTAATGTAGTAGTACTTTTTCTCCTTTTGCCCTGCAAGTTGTCACTAAATTTGTGCTATCATAATTGTTACCTTCATAGAATGCTTAAATAGTGGTACTTCTTTGACTTGTTAGGTTTGGACTATTTTCCTTTTCTTCTTCCATTTGTGAGGTAAATTAGTGGTTATTTTGGTGCTGGGTGCTAAGAAACTCGCAAAACAAGGGCCCTGCTCAAGAAGGATTGAAACTTAGTCCTTGCTGGGTACAAATTTAGAAATTTGTTATATAACTGTGGGGCAAGGGACAACATTTCACCAGGAAGTAGCAACTCCATCATCTTTCAGGAAGGGCTGATGGTTAGGGCATCTCTGAATGATTATTGGAGGGAAGTGGCTTTATGTCACACTTGTTTTCTGTAAGTCTTACTCTGTATCTACCCGACTTCAGATCATGGTGATTTAATTACATGGCCCAATCATGTTTTCTTTCCAGGGCTGCTTGAATGCTTGAATACttttttttttgagatggagtctcgttctgtcgcccaggctggagtgcagtggtgcaatctcggctcattgcaagctccgcctcccgggttcacaccattctcctgcctcagcctcccgagtagccaggactacaggcatgtgccaccatgcctggctaatgttttgtatttttagtagagatagggtttcaccatgttagccaggatggtctcgatctcctgacctcgtgatccgcccgccttggcctcccaaagtgctaggattacaggcgtgagccaccgcgcctggccAGAATGAATACTTTTAATTACTACTATGAGTCTTTTTTCAAAGTGCCTCCACCTTAAAAAAAATTCCTTATTTTATTCACTTGCCAGAATAATGTTGCATTTGAACCATGCCAACGGTAGCTTATTAAAACAGCATTTATTTTTCTCATTCATGGGTCAGCTGAACTTGTCTCTAGCCTTCAGATTGGGCTCAGGTGGGCTTTGTGTTTGTCATTCTGGAGCCTAGTTCCAGAGAGCAGTGGCTGCTTGAGTGTGGACTTGCTTATGGTGGGCCAAAGAGGGGCAAGGGAAAGCGCATTTACACTTTCTCGTATTCCATTGCCCAGAGATGGCATATAGCCGATCCCAAGTCAGTGCTATTCATTCATTTTTTTAAAAAAatttatttatttatttatttatttatttTCagacggggtcttgcactgttgcccgggctggagtgcagtggtggcatctccgctcactgcaacctccacctcccaggttcacatgattctcctgcctcagcctcctgagtagctgggattacaggtgtctgccactgcgcccggctaattttttgtatttttaagggagactgggtgtcactatgttggccagacagatctcaaactcctgacctcctgatccgccctcctcagcctcccaaagtgctgggattataggcatgagtcactgcgcccggccTATTCATTCATTCTTACAGTGAATTAGTAAATTCAACAAATAGGTTTTTTTAAAGCAATTAAGGCACTGAGGATATACAGAGAGTAAAATAGATGTCTCCTGACTTCTACTTGGAATTTTCTTTCCCTTACAGTTTTGATAGCTGCTTTCTCTTGAATAACTATGTCATCTCTTTCCACTTTGCATTGCTCCCAAGAGAGTAATGTAAAAGTTTTATCTGTGCATGCATATTCATGACACATTCATTTGTCATTATTTATCAAAAACCTGTTCCCTTCCCTGGCACTGGAGACATTGGAGAATGACAGTCTCAAGCAGTGCAGAGATGTAAGCAGGCAGAGGTAAGGACTTTGGTCTCAATAGCCTACAGGGTGCTTCATCCACTCACTGTATTCTGTGTGCCTGTGCCGCGGTGCAGGTGGTCAGTTGGAACCCCTGATGGGTATCTgggccactgcccaggccacacagagcctttgtgcaaattagaaaaggcccttccAAAGATACTTTATGAACGACTTGTAATAATTTAGTGATTTTATTTTCCAAAGcaaggcatttggttgctacctgctagaactgttacagtaaatacacagatctattttgtgagcaaatagtactgccttggatgtggtacccttgtgcagtgcacaacttggacaGTTCATACACAATGTTGTATTGAGATGATTGTTATTCTACATTGTATTTATTTAGATAGTGGGATTGAAAATAGGCTAAGATGGAGAACTGGGTGGGGAACAATTTGTAATCCTTTTTAGTTCATATGTCACAATCACAGAATTgagactagctagtttaaatccctgcatcttgcacatggtgaggaaaggtgaggacatttagatgacctttgcctgtcaccacacagctgtatggtagcagagctgggcgtgaaacctgcattcctggcctctccttttgtgGTGCTTACAGTGCTGTGTTAGGTCCAGTTTTACCTCTTAAATCTGTATTATTACttttttttcgagaccagatcttactctgtcgcccaggctggagtgcagtggcgtgatctcggcttgctgcaatctctgcaattctcatgcctcagcctcccaagtagctgggactacaggcgtgagccaccgtgcctggctaatttttgtatttttagtagagatggggtttcaccatgttggccaggctggtcttgaactcctgacctcaggtgatccgcccgttgcggcctccctaagtgctgggattataggcgtgagccactgcgcccggccTGAAATGTGTATTCTTAAGTCCGCCTTTCAAAGTTGAGTACTGCATTCTTGCGGCTCTACCTAAGTTTCTCCTAGAATCTCCCTGCACTTCTTGTTTTGCTGCCATCAGGTAATTTGTGCATTAGAACTAGCTTGGAACAGAATGGGTAAACTTCTGTGAAGTTAGACACTTGCCTCTTAGAGGCATATCCAGTGAGTCTTTAAAGCCCTACGTTATAGAAAAATGTGAAGTATGTCTAATAAAGGAGTACAGTGGAAGGTTTAAAAGCACATTGCTGATTAGTGGGGTCAGGATGGGAGGAGAGCCCTGATTTTAATGCAGTGTCATAGTCTCATAGGTGATTTCCCCAAAAGCAAATAAATGCTCGATGGATTTTGGGTCCACCATGCATCTCTGAAGTAGAAGTGACAGATTTTCAAGGCTAAGGTAAGTATAGCATTTTCTCAACCCTATTACAATAGAGCACAGGATCATAACTGTTCTGTTTGCTCTGATGCGTCCCGCAGAGCAGTGCTTTTTCTCGGTGTGAACTGTGGATCACTTGTCTCAGTCATCAGGATTCCTGGACCCTGTAGGATTTACTCTCAATCTTTAGGGGTAGAGACTAGGAGCCTACATTTTGAACAAGCATCTTTTTATTTTGATGAAGTTTGCATTATTACTCCTAACAACGTGCCCTTTGGCAGGTAGCTTCCACTTTTCTGGCCTCATTATCTGTAAAATTGCATACTTAGTTATCATTGAGGTCTCAAATGCAGTTCGGGTTCCTGGTTGGTGAACAATTAGATGGGAAGGCTGAAAAAAAAAATActcctgagattctgaatctgtaagtatgcaatgggacctgagaatcaatctaatttctaaaagattcccagatagaactttgttgagctatgtttagggaccaGTGCACACCTTGGTGATAGAACCTTTTTGAAACTTTGAAAAAGTTAAAAGGGTTCTGTGTAATGTTACCTAAGAAGCTTATTTTTAAAAAAGGAAAGCAGTGCTTAGGGCCATATTGTTTTGAAATAGGATCTGAGCACCATTTAAATTTTTATAAATTATTTTTTAGAGGCATCACTTCTTTAAAGCCCATCAGATTAATGTGCCATTGGTTTGAAAACCATGACATGAGATGATTTCTTAAGGTTTTATTTGTGTCAGACATGAATTTTAGAGTATTTCTGGGCTATAGGTCATTACAGCTTTACTTAtttattttttggagacagggtctcactctgtcacccaggctggagtgcagtgtcgtggtcttgggtcactgcatccttgacctccccagctcaagcgatcctcccgcctcagcctcccgagtagaaggtactacaggtgtgtgacaccacgcctggctcatttttgcattttgtgtagagagggggttttgccattttacccaggctggtctcgaactcctgagctgatcctcccacctcggcctcccaacgtgctgggattacaggcattagccactgtgcccagcTGGGTATGGATTTCTGAGTGGAGGGAATGTGAACAAAGGAGGGCCCAGGCATGTTTGCAGAGTGGCTGGGGGCCCTGCTTCACCACGGCATAGGGACGGGTGCAGTAGGAAGAAAGGTAGCCTCAAGGCCCCCATAAATAAATTGGTGCATTAAGGAAGGAATATTAATCACATCCAGGAGGGCTCTGCCCTAACTGCTGAGAATCATAAAAGAAATGGGGACATATTCTGGCGAAATAACAGCTTTGttaattgagctcttactgtgtgcctttgcactgtgttaagcacatggtgttatcacacttgctactcacaacagctctgaggttgatagtacaggtatcttctttttatggagcaggactctgagacATCATAATTGCTTGGTATATGCAGCCAGAGTTGGAAATCCTATCTGTCTGATTTTGGAAACTGTGTGCTTACCATTACATATCTTATGTGGAAATAAAATGTATATGATTAATTACAAAGCTGAAAATCGTAGTTGAAGCATCATATAGTGCACAGGGCAAGCAAAGCAGCATAAAAGGCTTCATCTGTAAGGGTAGGTTTGTTGGGTAGGAGCTTTTTGGGGGAGGTGACTTTAGGATCAGTTGTAGCATGAGAGAATATGACACCTTCTTCCTTTAGAGGATCTAAAGGTGTAGCTTTAGAGGATTGTAGGGTGCCTTTGCCCATTGTGTCATTTGGTCCTTCTTAAAATttgagtgtttattctctacatggcactcttttaagcctttgtgtgaattaactcagtcttctcagcaatcccccattttttcatatgtggaaactgaggcatgttatgatacaaagcttgtccaagaattcagagctagcttgtccaagaattcagagctagtaagtgagggaactgggatttgaatttaagcagtctgtctctagagtctgctcAGCTGGCCtttttttctttcttcttcttcttcttctttttttttttttttGTATAATAGGCCTGTGAGTTGGGAAGAGCAGGGTTTGTTTGGTGAGAAAGTTGCACCTTAGTGAATACCCAAGGTCTGAGGGAGGCTTGGAGCCAGCTCTGCAACCTGGCTCCCTTCTTTCATTAGCTTGACCCAAGCACAGGGAGATGACTGGGGCTCTGCCTTCATCTTCTCTGCAAACGGTCAGGGATACTCATGCAGTTTTTGAGTTTAAGTAGTAAACTCCTAAACTTCAAGTCATGTTTGTATTAGTGatttcacttgacctcagtacaactctgtaaaagaggcagggatggatgatgtcatttgtcaaatggtaaaactgaggcGAAACAACTTGGCATTGTTGGTGTTGTGCGAAGTACATGCATAGGCTTtggatttgagtttggctctgccactaacttgatctatgtcttcaggcaagtaacttaaatgctctgagtgttgcattctctgtgaagtggaaatagctgtactttgcccaagagttgtgagagtgacatgaattgctatatgtgaggttcttagcatagtgcctggcaagtagaaggtactcaTCTGTGAATGGGGTAGATAGCAGCTGTCTTCATCACTGTCATCATTGTTGGCTCACATCAAATCAGGACCAGAAAACCCTGTTGACTTCTGGGTCTTAAACTGCTGTATCAGTGAGGGGCTTCCTCCTCATACTCATTGCCAGGAGTAGAGTAAGGCTTTTAATTTCATCTCTAACCAACTCTGATAGGGCTGGAAATGTGTATGGAGTTCCAGACCCACCATGGGGCCCCAGTGCTAGCTTCTTAGCCCTCCTTTGTAAGGTTTGCACTAGTTTGATGGGAGAGGGATTTTTTTTGTCTTGATTCTGAAGCTCTTAAAGAAATGCTCCTTTTTCTCCATAACTTGAGGATTTCACAATTGTATTGGAATTATTGGTGTTAAGGAGTTAGGTCCATCTCTTGGCAGCTTGTGAAGGGTGGGCAGGCACCTGTGAATTCTTCACTGGCTTCTTGTAAGAATGACTTTACTGGAGGGTGCTGAGTTTGTGATTATCTCCTCTGCTGCTAGAAAACTCCGTGAACCCTGGTACATATAGCGTGATAAATCAAGTCCTGTTTTTGCTCCTAACTTGCATTATGGTGTTTGATACTATATCTTCATTTCTCCCATGGTAGTAATAACACTGTTGgaaagagctctcagttggaagttgaagatccaggttctagttgaggcaccagagtttccttgggcaagttgccatacctttttgggccttggtttcctcatctcaataaaatgagTTTCTGTTC

>NM_001791.4 

GCAGTGCTGCCAACGCCCCGGTGGAGAAGCTGAGGTCATCATCAGATTTGAAATATTTAAAGTGGATACAAAACTATTTCAGCAATGCAGACAATTAAGTGTGTTGTTGTGGGCGATGGTGCTGTTGGTAAAACATGTCTCCTGATATCCTACACAACAAACAAATTTCCATCGGAATATGTACCGACTGTTTTTGACAACTATGCAGTCACAGTTATGATTGGTGGAGAACCATATACTCTTGGACTTTTTGATACTGCAGGGCAAGAGGATTATGACAGATTACGACCGCTGAGTTATCCACAAACAGATGTATTTCTAGTCTGTTTTTCAGTGGTCTCTCCATCTTCATTTGAAAACGTGAAAGAAAAGTGGGTGCCTGAGATAACTCACCACTGTCCAAAGACTCCTTTCTTGCTTGTTGGGACTCAAATTGATCTCAGAGATGACCCCTCTACTATTGAGAAACTTGCCAAGAACAAACAGAAGCCTATCACTCCAGAGACTGCTGAAAAGCTGGCCCGTGACCTGAAGGCTGTCAAGTATGTGGAGTGTTCTGCACTTACACAGAAAGGCCTAAAGAATGTATTTGACGAAGCAATATTGGCTGCCCTGGAGCCTCCAGAACCGAAGAAGAGCCGCAGGTGTGTGCTGCTATGAACATCTCTCCAGAGCCCTTTCTGCACAGCTGGTGTCGGCATCATACTAAAAGCAATGTTTAAATCAAACTAAAGATTAAAAATTAAAATTCGTTTTTGCAATAATGACAAATGCCCTGCACCTACCCACATGCACTCGTGTGAGACAAGGCCCATAGGTATGGCCCCCCCCTTCCCCCTCCCAGTACTAGTTAATTTTGAGTAATTGTATTGTCAGAAAAGTGATTAGTACTATTTTTTTTTGTTGTTTCAAAAAAAAAAtttttgtgtgtgtgtgttttttttttttttttttttgttgtttAAAAGCAAGGCATGCTTGTGGATGACTCTGTAACAGACTAATTGGAATTGTTGAAGCTGCTCCCTGGTTCCACTCTGGAGAGTAATCTGGGACATCTTAGTGTTTTGTTTTGTTTTTTTCCCTCCTCTTTTTTTTGGGGGGGAGTGTGTGTGGGGTTTGTTTTTTAGTCTTGTTTTTTTAATTCATTAACCAGTGGTTAGCCCTTAAGGGGAGGAGGACGGATTGATTCCACATTCCACTTCCTAGATCTAGTTTAGAAAACATGTTCCCCATCTGGTGCTCTTAGGAAGGAGTATAGTAAATGCCTCATTTAATAACATACTCCTTTTTGAAAGTTGCCTTTTCTCTCCACCCTTGAGTAGATCCAGTATTTGATGAAACTCATGAAAGTGGGTGGAGCCCATCTTGCCCCTCCTCTTTTCTAGGACGCACTATATGTGACTGTGACTTTCAAGGACATTTGTTTGCCATTTGCTGATTTTTTTGGGAAGTTAATTTCTAACTTCTTTCACTGATAAATGAAGAAAAGTATTGCACCTTTGAAATGCACCAAATGAATTGAGTTTGTAATTAAAAAAATTTTTTTCCCTTTCAGTCATTGTCTTATATGCTTAGCATAGATTTGCAGCTCAGTAGTATATGGTGTTCCTAGAATGCAGCTGAAGACCTGTTATGTAGAGGAAATACGAGGGGTGGTGCTAGAAGACAGACATCTGTGGAATGATTCACATCCTCTCAAGTTAGGAGGATGGAGGCCTGCTTCATTAAGAAGCTGGGGGTAGGGTGGGGGTGGGGAGAACACTTAACAACATGGGGACCAGTCAGGGGAATCCCCTTATTTCTGTTTTGCATATGAGGAACCCTAGAGCAGCCAGGTGAGGCTCTCTAGTTTAATAAAAATCATGGAAAGACTCTTAATGCAGACTCTTCTTAAGTGTTAATAGGGATTTTTTCAGCTTATTTTGGTTGCAGTTTCCAATTTTTAAAAATGTTGAGGTAATCTTTCCCACCTTCCCAAACCTAATTCTTGTAGATGCATTAGTGTTGAACCAATGCTTTCTCATGTCTCAATTCTTTGTATATGCATTCTTTTCAGATGTATTAAACAAACAAAAACCCTTCACAAGCCAGCCTGAGGGTTGTTATTTTCCCTCCGTCTCTTACTTTTCAGATATTGAGGAGTGGGAATTTGACTCTTGATAACATCAATTTCTAACAAACTTTGGGATAAAATTTTAAAGCTTTATTATTTTTATTTTCTGGCATTTTAGTTTGAGATAATATTTAGCCCTCTATATGTTCAGGTTTGTGCTTTCTCCTCTAAGTTTGACCCTTCCCTTAAATACCAAGTAGGTCCATAATAATTCTTAGTGAAGCAGTGTTCAGGAAGCTCACTGCTCATGGTGGAAGGAAATGTCAGTGTACCTTTAATCCATAGATCATTGAAAAGCAGCTCATTTTCCCCCAAGTTTTCTGCATCAGTGGTTCTCCAActggagtgcagcttgaacaatgtgatttttaagttttccaggcatttctaaaatgtagccaagtttgggaatcacCACACCTAGTTGGTTATCTCAAACTACTACTATCAGAATACAGGTTCTGTGCTGCGAATCTGAATATGGGATACATTTTCTTTAGGTAGCAAGAAAGGTTTATTTACCTTTAGGACATTATACTGATCTGCATGAGAATCTTAGAAACTAAGAACCCTTAAAATCAGTTAAGGTTGGTACACTGTGGCCTCATTTTGATAGTTCTCTGCATGGAGTCATGTTTGGCATGATTTGCATACTGTGCTAGAATTAAGCTGGGTTGGTTGAGAAGGGGTTAGGAAGAGGCAGATGTAAGCTTTAACAGTTCTAACCAAGAAATGCATCTTATTTATTCCTTGTTGACTATACTAGGGAGAGATACCTGGATCATGTGATACCCTGGAAAGCAGGGACATATGTATCCTTAGTGTAGTCAGGGGCGTATAGGTCCTTGACTATTGCTATATCTTTGTCCTAAAGCAATGCTTGACATGATATGGCTCTAGAAGTAGTCATTGGATGGGTATATTATTTTATAAATGAGTAAGTGAAATAAAGCAGGTCATACAGTTGTGTCAACGAATTATCCGTGTATCAGAAGAACAAGGATGATGGGGATTGATTGAAGCTAATGTTTTCTTAAATATTTTCAGATTGATTTCTGCATGTCAGAAGAACTTGGGTAGCAAGTGGATGCAGCTTAGGTTTTCCATTTAAATATTGTTTTCTATTTGACGTAACAAACTTGCTTATAGTCGTGGCTTAGAAGGTGAGTGATATTCTCCAGGGAGTATGATTTAGAGGCTGGAAAGGGTTATTGAAAATAGTCCTTACAGGCTTAGTTTGTGTCAGAATTTATAGTATTTAATACGATGTTAATATATTATTGCTATTTATAAGTGTTTTACTGAACATCCTAGAAATAGAtttttttttttttttttttttgagacggagtctcgctctgtcgcccaggctggagtgcagtggcgcgatctcggctcactgcaagctccgcctcccgggttcacgccattctcctgcctcagcctcccgagtagctgggactaccggcgcccgctaccacgcccggctaattttttgtatttttagtagagacggggtttcaccgtgttagccagaatggtctcgatctcctgacctcgtgatccgcccgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcgcccggccAGAAATAGATTTTATAGTTAAAGCGATGTTCTTCAAGCTGGACTTTATGCCACAAGGGGAGTGTATTCTAAAGGGGAAGAAAAGGATTGTGGTTTAAAAGAACAATTGTAATATTTCCTTCATTCTGAGGTGTATTTTTCTCACATTTTCATATTGTAATTAGGATACCTGTTAACATTGGTGTACATTTAATGTAGTAGTACTTTTTCTCCTTTTGCCCTGCAAGTTGTCACTAAATTTGTGCTATCATAATTGTTACCTTCATAGAATGCTTAAATAGTGGTACTTCTTTGACTTGTTAGGTTTGGACTATTTTCCTTTTCTTCTTCCATTTGTGAGGTAAATTAGTGGTTATTTTGGTGCTGGGTGCTAAGAAACTCGCAAAACAAGGGCCCTGCTCAAGAAGGATTGAAACTTAGTCCTTGCTGGGTACAAATTTAGAAATTTGTTATATAACTGTGGGGCAAGGGACAACATTTCACCAGGAAGTAGCAACTCCATCATCTTTCAGGAAGGGCTGATGGTTAGGGCATCTCTGAATGATTATTGGAGGGAAGTGGCTTTATGTCACACTTGTTTTCTGTAAGTCTTACTCTGTATCTACCCGACTTCAGATCATGGTGATTTAATTACATGGCCCAATCATGTTTTCTTTCCAGGGCTGCTTGAATGCTTGAATACttttttttttgagatggagtctcgttctgtcgcccaggctggagtgcagtggtgcaatctcggctcattgcaagctccgcctcccgggttcacaccattctcctgcctcagcctcccgagtagccaggactacaggcatgtgccaccatgcctggctaatgttttgtatttttagtagagatagggtttcaccatgttagccaggatggtctcgatctcctgacctcgtgatccgcccgccttggcctcccaaagtgctaggattacaggcgtgagccaccgcgcctggccAGAATGAATACTTTTAATTACTACTATGAGTCTTTTTTCAAAGTGCCTCCACCTTAAAAAAAATTCCTTATTTTATTCACTTGCCAGAATAATGTTGCATTTGAACCATGCCAACGGTAGCTTATTAAAACAGCATTTATTTTTCTCATTCATGGGTCAGCTGAACTTGTCTCTAGCCTTCAGATTGGGCTCAGGTGGGCTTTGTGTTTGTCATTCTGGAGCCTAGTTCCAGAGAGCAGTGGCTGCTTGAGTGTGGACTTGCTTATGGTGGGCCAAAGAGGGGCAAGGGAAAGCGCATTTACACTTTCTCGTATTCCATTGCCCAGAGATGGCATATAGCCGATCCCAAGTCAGTGCTATTCATTCATTTTTTTAAAAAAatttatttatttatttatttatttatttTCagacggggtcttgcactgttgcccgggctggagtgcagtggtggcatctccgctcactgcaacctccacctcccaggttcacatgattctcctgcctcagcctcctgagtagctgggattacaggtgtctgccactgcgcccggctaattttttgtatttttaagggagactgggtgtcactatgttggccagacagatctcaaactcctgacctcctgatccgccctcctcagcctcccaaagtgctgggattataggcatgagtcactgcgcccggccTATTCATTCATTCTTACAGTGAATTAGTAAATTCAACAAATAGGTTTTTTTAAAGCAATTAAGGCACTGAGGATATACAGAGAGTAAAATAGATGTCTCCTGACTTCTACTTGGAATTTTCTTTCCCTTACAGTTTTGATAGCTGCTTTCTCTTGAATAACTATGTCATCTCTTTCCACTTTGCATTGCTCCCAAGAGAGTAATGTAAAAGTTTTATCTGTGCATGCATATTCATGACACATTCATTTGTCATTATTTATCAAAAACCTGTTCCCTTCCCTGGCACTGGAGACATTGGAGAATGACAGTCTCAAGCAGTGCAGAGATGTAAGCAGGCAGAGGTAAGGACTTTGGTCTCAATAGCCTACAGGGTGCTTCATCCACTCACTGTATTCTGTGTGCCTGTGCCGCGGTGCAGGTGGTCAGTTGGAACCCCTGATGGGTATCTgggccactgcccaggccacacagagcctttgtgcaaattagaaaaggcccttccAAAGATACTTTATGAACGACTTGTAATAATTTAGTGATTTTATTTTCCAAAGcaaggcatttggttgctacctgctagaactgttacagtaaatacacagatctattttgtgagcaaatagtactgccttggatgtggtacccttgtgcagtgcacaacttggacaGTTCATACACAATGTTGTATTGAGATGATTGTTATTCTACATTGTATTTATTTAGATAGTGGGATTGAAAATAGGCTAAGATGGAGAACTGGGTGGGGAACAATTTGTAATCCTTTTTAGTTCATATGTCACAATCACAGAATTgagactagctagtttaaatccctgcatcttgcacatggtgaggaaaggtgaggacatttagatgacctttgcctgtcaccacacagctgtatggtagcagagctgggcgtgaaacctgcattcctggcctctccttttgtgGTGCTTACAGTGCTGTGTTAGGTCCAGTTTTACCTCTTAAATCTGTATTATTACttttttttcgagaccagatcttactctgtcgcccaggctggagtgcagtggcgtgatctcggcttgctgcaatctctgcaattctcatgcctcagcctcccaagtagctgggactacaggcgtgagccaccgtgcctggctaatttttgtatttttagtagagatggggtttcaccatgttggccaggctggtcttgaactcctgacctcaggtgatccgcccgttgcggcctccctaagtgctgggattataggcgtgagccactgcgcccggccTGAAATGTGTATTCTTAAGTCCGCCTTTCAAAGTTGAGTACTGCATTCTTGCGGCTCTACCTAAGTTTCTCCTAGAATCTCCCTGCACTTCTTGTTTTGCTGCCATCAGGTAATTTGTGCATTAGAACTAGCTTGGAACAGAATGGGTAAACTTCTGTGAAGTTAGACACTTGCCTCTTAGAGGCATATCCAGTGAGTCTTTAAAGCCCTACGTTATAGAAAAATGTGAAGTATGTCTAATAAAGGAGTACAGTGGAAGGTTTAAAAGCACATTGCTGATTAGTGGGGTCAGGATGGGAGGAGAGCCCTGATTTTAATGCAGTGTCATAGTCTCATAGGTGATTTCCCCAAAAGCAAATAAATGCTCGATGGATTTTGGGTCCACCATGCATCTCTGAAGTAGAAGTGACAGATTTTCAAGGCTAAGGTAAGTATAGCATTTTCTCAACCCTATTACAATAGAGCACAGGATCATAACTGTTCTGTTTGCTCTGATGCGTCCCGCAGAGCAGTGCTTTTTCTCGGTGTGAACTGTGGATCACTTGTCTCAGTCATCAGGATTCCTGGACCCTGTAGGATTTACTCTCAATCTTTAGGGGTAGAGACTAGGAGCCTACATTTTGAACAAGCATCTTTTTATTTTGATGAAGTTTGCATTATTACTCCTAACAACGTGCCCTTTGGCAGGTAGCTTCCACTTTTCTGGCCTCATTATCTGTAAAATTGCATACTTAGTTATCATTGAGGTCTCAAATGCAGTTCGGGTTCCTGGTTGGTGAACAATTAGATGGGAAGGCTGAAAAAAAAAATActcctgagattctgaatctgtaagtatgcaatgggacctgagaatcaatctaatttctaaaagattcccagatagaactttgttgagctatgtttagggaccaGTGCACACCTTGGTGATAGAACCTTTTTGAAACTTTGAAAAAGTTAAAAGGGTTCTGTGTAATGTTACCTAAGAAGCTTATTTTTAAAAAAGGAAAGCAGTGCTTAGGGCCATATTGTTTTGAAATAGGATCTGAGCACCATTTAAATTTTTATAAATTATTTTTTAGAGGCATCACTTCTTTAAAGCCCATCAGATTAATGTGCCATTGGTTTGAAAACCATGACATGAGATGATTTCTTAAGGTTTTATTTGTGTCAGACATGAATTTTAGAGTATTTCTGGGCTATAGGTCATTACAGCTTTACTTAtttattttttggagacagggtctcactctgtcacccaggctggagtgcagtgtcgtggtcttgggtcactgcatccttgacctccccagctcaagcgatcctcccgcctcagcctcccgagtagaaggtactacaggtgtgtgacaccacgcctggctcatttttgcattttgtgtagagagggggttttgccattttacccaggctggtctcgaactcctgagctgatcctcccacctcggcctcccaacgtgctgggattacaggcattagccactgtgcccagcTGGGTATGGATTTCTGAGTGGAGGGAATGTGAACAAAGGAGGGCCCAGGCATGTTTGCAGAGTGGCTGGGGGCCCTGCTTCACCACGGCATAGGGACGGGTGCAGTAGGAAGAAAGGTAGCCTCAAGGCCCCCATAAATAAATTGGTGCATTAAGGAAGGAATATTAATCACATCCAGGAGGGCTCTGCCCTAACTGCTGAGAATCATAAAAGAAATGGGGACATATTCTGGCGAAATAACAGCTTTGttaattgagctcttactgtgtgcctttgcactgtgttaagcacatggtgttatcacacttgctactcacaacagctctgaggttgatagtacaggtatcttctttttatggagcaggactctgagacATCATAATTGCTTGGTATATGCAGCCAGAGTTGGAAATCCTATCTGTCTGATTTTGGAAACTGTGTGCTTACCATTACATATCTTATGTGGAAATAAAATGTATATGATTAATTACAAAGCTGAAAATCGTAGTTGAAGCATCATATAGTGCACAGGGCAAGCAAAGCAGCATAAAAGGCTTCATCTGTAAGGGTAGGTTTGTTGGGTAGGAGCTTTTTGGGGGAGGTGACTTTAGGATCAGTTGTAGCATGAGAGAATATGACACCTTCTTCCTTTAGAGGATCTAAAGGTGTAGCTTTAGAGGATTGTAGGGTGCCTTTGCCCATTGTGTCATTTGGTCCTTCTTAAAATttgagtgtttattctctacatggcactcttttaagcctttgtgtgaattaactcagtcttctcagcaatcccccattttttcatatgtggaaactgaggcatgttatgatacaaagcttgtccaagaattcagagctagcttgtccaagaattcagagctagtaagtgagggaactgggatttgaatttaagcagtctgtctctagagtctgctcAGCTGGCCtttttttctttcttcttcttcttcttctttttttttttttttGTATAATAGGCCTGTGAGTTGGGAAGAGCAGGGTTTGTTTGGTGAGAAAGTTGCACCTTAGTGAATACCCAAGGTCTGAGGGAGGCTTGGAGCCAGCTCTGCAACCTGGCTCCCTTCTTTCATTAGCTTGACCCAAGCACAGGGAGATGACTGGGGCTCTGCCTTCATCTTCTCTGCAAACGGTCAGGGATACTCATGCAGTTTTTGAGTTTAAGTAGTAAACTCCTAAACTTCAAGTCATGTTTGTATTAGTGatttcacttgacctcagtacaactctgtaaaagaggcagggatggatgatgtcatttgtcaaatggtaaaactgaggcGAAACAACTTGGCATTGTTGGTGTTGTGCGAAGTACATGCATAGGCTTtggatttgagtttggctctgccactaacttgatctatgtcttcaggcaagtaacttaaatgctctgagtgttgcattctctgtgaagtggaaatagctgtactttgcccaagagttgtgagagtgacatgaattgctatatgtgaggttcttagcatagtgcctggcaagtagaaggtactcaTCTGTGAATGGGGTAGATAGCAGCTGTCTTCATCACTGTCATCATTGTTGGCTCACATCAAATCAGGACCAGAAAACCCTGTTGACTTCTGGGTCTTAAACTGCTGTATCAGTGAGGGGCTTCCTCCTCATACTCATTGCCAGGAGTAGAGTAAGGCTTTTAATTTCATCTCTAACCAACTCTGATAGGGCTGGAAATGTGTATGGAGTTCCAGACCCACCATGGGGCCCCAGTGCTAGCTTCTTAGCCCTCCTTTGTAAGGTTTGCACTAGTTTGATGGGAGAGGGATTTTTTTTGTCTTGATTCTGAAGCTCTTAAAGAAATGCTCCTTTTTCTCCATAACTTGAGGATTTCACAATTGTATTGGAATTATTGGTGTTAAGGAGTTAGGTCCATCTCTTGGCAGCTTGTGAAGGGTGGGCAGGCACCTGTGAATTCTTCACTGGCTTCTTGTAAGAATGACTTTACTGGAGGGTGCTGAGTTTGTGATTATCTCCTCTGCTGCTAGAAAACTCCGTGAACCCTGGTACATATAGCGTGATAAATCAAGTCCTGTTTTTGCTCCTAACTTGCATTATGGTGTTTGATACTATATCTTCATTTCTCCCATGGTAGTAATAACACTGTTGgaaagagctctcagttggaagttgaagatccaggttctagttgaggcaccagagtttccttgggcaagttgccatacctttttgggccttggtttcctcatctcaataaaatgagTTTCTGTTC

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