Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name AK3P2
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:143055222-143057835  UCSC
Coordinates (T2T) chr8:144199246-144201858  UCSC
Coordinates (hg19) chr8:144136639-144139252  UCSC
Strand -
Parental Sequence NM_001199855.2
Parental seq. overlap 1966 bp
Parental seq. overlap (%) 47.8%
Genomic Region Intergenic
Retrocopy Summary AK3P2, located on chr8:143055222-143057835, is a retrocopy of the parental gene AK3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AK3
Full Name adenylate kinase 3
Also known as AK3L1|AK6|AKL3L|AKL3L1|FIX
Coordinate chr9:4709556-4742043
Strand -
Gene summary The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes AK3P4
Bonobo Pan paniscus AK3P4
Gibbon Nomascus leucogenys AK3P4
Green monkey Chlorocebus sabaeus AK3P1
Rhesus Macaca mulatta AK3P3
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>AK3P2
TAGTAAAAAAGAGACTAAAGGCTTATAAAGCCAAACAAAGCCAGTCCCGGAATATTACCAGAAAAAAGGGGGTGTTGGAAACATTCTCCGGAACAGAAACCAACAAGATTTGGCCCTATATATACACTTTCCTACCAACTAAAGTTGCACAAACAAGCCAGAAAACTTCAGTTACTCCATGAGGAGAAATGTGTGTAACTATTAACAGGAAGATGGGCAAACCTCCTAGTCCCTGCATTTAGAAGCACTTTTCCTAAGACTTCCAATATGTATGAATTCTTTGAAAACTATATTACTTTTATTTCTACTGATTTTATTCTGGATACTAAGGATGTGCCAGATGAGTCAGATACTAAGATTCATCCTTTGAAATCATCTAGTGTGTTTTATGCAGTTATCCTCAAAAATATCAGCGATGCCTGAACTTTTAAAACATCTGTTAAAGCAAAATTAAACGAGCATTTTGTAGTAATCTCACTTTTTGTTCAGTTAATAAGTGGTTGATAAAGTTTCCATATTTTTCTGGAAAAGTTAAAAAAAGTTACATGTCATTTGGGGAAAATATGTAATCAGAAATTTTTGCATAGATTCATTCCAAAAAAAAGGCATTTCTAGCCTTTTTGTGGAACATGGTGAGACATTATATAAATTCCAGAAAGAAAACAACTGGATTTACAGATTTATTGTAAGACACAAATTCACTTCTGCCTTTACAGTAAGAAATGTATGTGCTAACCATATATGCTGTATTTATTTTGTTGTTAAGCATACTTTCAGTTTGCTCAGAATTTTCAATTTGCTATAAAAATGTATCAATTAGCATATAGAAAAATATTACTTTAAGATGACTTGTTTCTTTTGAAAATACATATATATTCGGGGTTATGATTTATGTCAGAAATTGACATCATAAGTCCTTGGACAAGCACCAAAGTTGAATGAATTTTCAACAAAATGGAATTAAAGTCTATATGTTTCCCGATGTGACTCAGGTTGATAAATGTGTTTTAGGATCTAGTTGCCGGTTTCTCTTTTCGATCCAAATGTATGATCTACCCTGATAAATAACAAGTGATAGTGCCACCCCCACCACCAAAAACAGAAAAGAAAAAAGAGGAAACCCGCGGCACTGTGTAAATAAAGTAGGCTCACTGTGTCATGAGTAAACAGATGAGGCACGCCTGGGAAATGCTCCCTTGGCATAAATAGCAATCAATCATAATTAGTAAACAGGTGTGCCAATAAAAAGAATTTATGTGACAGGTTAACAAGGACCAGGAAAGTGAGTGAGTTTCCTGAAGGAGTTCTTTGTTCCTGATCAGAGAACTCGATACCTGTTAGCATTCACTGCCGCCTTACTGTAAGGAGAAAGAACTCTATTGGCGTCGTCTAAGCAGCCATTTAAAAATTGGAATCTACAGTGATTCCTGAGTGGGCAGCAAGGGTGGCTGCTGATGTGCTGTGTGGTCTGGGAGAAGTGGAGGAAAAGCCCGATGGCGTCTTTCACGGCGTATTTACTCTTCCTTTACTTGATGCCAAGTCAAATGAAACAAGCGCTCGTACAAGCTGTTATTAATTGCCTTTAAAAATCTGGTCCGTTTTTTTCCAGGTACTTAAAATACCAGTGCCAGTAAGTGGTTCTTACGTATTTTGGGGGGAAATTTTTATTTTTCTTTTCTTCTGATATTTTAAAAATTCATTGATCTTTCAAGATGAGCCAAGGTTTTTTAAAAGAATGACAGTAAACACTTCATTCTTTACAAAACTTTCTATAATGCCTTATTTGAATGTTAATCGTATGTGCTTTCTAAAAATGTTGTGAACTGCCAAACTTATGGATTCTCACTAGGTTATCAGGCATACATTAGTCTTTATCAGAATAAAATGAAATGTCATTACTGTGGCTATTACTTTGTCCTTGGTCCTTCCCAGGGCCTGCTCCGCCCCAGCTTCCTTCCTGCTGCCTGATGTCTCAATGGCTTCTGAATGACTGTGTTCTAATAAATGATCTTAACTCATTCAGCATGAGGATGATAAACCAGAGACGGTTATCAAGAGACTAAAGGCAGAGCCGAAAAGTCTCACCCAGTCTAGCTGTTGATGGTTTTTCAAGAACACATCCACAGGCAGAAGCCCTAGATAGAGCTGATCAGATCGACACAGTGATTAAGCTGAATGTGCCCTTTGAGGTCATTAAACAACGCCTTACTGCTTGCTGGATTCATCCCGCCAGCGGCTGAGTCTTCAACATTGAATt
>NM_001199855.2
GAGTGGGCGCCAGGTGGAGGTGGGGCCAGGGTTGTCAAGGGAGCACGAAAGGGGTCGCGGTGTGTCCGGCAAGGACTGGAAATTGGCGTGTTAGCCAAGGCTTTCATTGACCAAGGGAAACTCATCCCAGATGATGTCATGACTCGGCTGGCCCTTCATGAGCTGAAAAATCTCACCCAGTATAGCTGGCTGTTGGATGGTTTTCCAAGGACACTTCCACAGGCAGAAGCCCTAGATAGAGCTTATCAGATCGACACAGTGATTAACCTGAATGTGCCCTTTGAGGTCATTAAACAACGCCTTACTGCTCGCTGGATTCATCCCGCCAGTGGCCGAGTCTATAACATTGAATTCAACCCTCCCAAAACTGTGGGCATTGATGACCTGACTGGGGAGCCTCTCATTCAGCGTGAGGATGATAAACCAGAGACGGTTATCAAGAGACTAAAGGCTTATGAAGACCAAACAAAGCCAGTCCTGGAATATTACCAGAAAAAAGGGGTGCTGGAAACATTCTCCGGAACAGAAACCAACAAGATTTGGCCCTATGTATATGCTTTCCTACAAACTAAAGTTCCACAAAGAAGCCAGAAAGCTTCAGTTACTCCATGAGGAGAAATGTGTGTAACTATTAATAGTAAGATGGGCAAACCTCCTAGTCCTTGCATTTAGAAGCTGCTTTTCCTAAGACTTCTAGTATGTATGAATTCTTTGAAAATTATATTACTTTTATTTCTACTGATTTTATTTTGGATACTAAGGATGTGCCAAATGATTCGGATACTAAGATGCATCGTTTGAAATCATCTAGTGTGTTGTATGCAGTTATCCTCAAAAACATCAGCGATGTCTGAACCTTTAAAACATCTGTTAGAGCAAAATTAAAAGAGCATTTGGTAGTAATCTAACTTTTTGTTCAGTTAATAAGTGGTTGATAAAGTTTCCATATTTTTCTGGAAAAGTTAAAAAAAGTTACATGTCATTTGGAGAAAATACGTAATCAGAAATTTGTGCATAGATTGATGCCAAAAAAGACATTTCCAGCATTGTGGAACATGGTGAGACACTATATAAAATTCCAGAAAGAAAGCAACTGGATTTACAGATTTATTGTGAGACACAAATTCACTGCTGCCTTTACACTAAGAAATGTATATGTTAACCATATATGCTGTATTTATTTTGTCGTTAAGCATACTTTCAGTTTACTCAGAATTTTCAATTTGCTATAAAGATGTATCAATTAGCATATAGAAAAATATTACTTTAAGATGACTTGTTTCCTTTGAAAATACCTGTGTACTGAGGGTTATGATTTGTGTCAAAAATTGACATAAGTGCTTTTACAAGCACCAAAGTTGAATGAATTTTCAACAAAATGTAATTAAAGTCTATGTTTTCAGTTATGACTCAGGTTAAGAAATGTGTTTTAGGATCTACTTGCTGGTTTTTCTTTTTGATCCAAATGTGTGATCTGCCCTGATAAATAACAAGTTATAGTACCATCTCCCCCGCCAATAAAAAAGAGAAGAAAAAAGAGAAACCCGTGGCACTATGTAAATAAAGTAAGCATACTTTGTTGTTAGTAAATAGATGAGGCATGCCTGGGAAATGCTCCCTTGGCATAAATAGCAATCAATCATAATTAGTAAACAGGTGTACCAATAAAAAGAATTTACATGATAGGTTAACAAGGACCAGGAAAGTGAGTTTCCTGAAGGAGTTCTTTGTTCCTGATCAAAGAAATTGATACCTGTTAGCATTCACTGCCACCATATTTTAAGGAGAAAGAACTCTATTGGTGTCGTCTGAGCAGCCATTTAAAAATTGGAATCTAAAGGATGGTTGCTGATGTACTGTGTGGTCTGGTAGAAGTGGGGAAATATGAGAGATGGAGGAAAAACTTGATTATGTCTTCCATGGCATATTTACTCTTACTTTACTTCGTGCCAAATCAAATGAAACAAGCCGTCTTACAAGTCGTTATTGCCTTTAAAAATCTGTTCCGTTTTTTTCCCAGGTACTTAAAATACAAGTGCCAGTAAGTGGTTCTTATGTGTTTTGGGGGGAAAATTTTATTTCCCTTTTCTTCTGATATTTAAAAAATTCATCGATCTTTCAAGATGAACCAAGGTTTTTTAAAAGAAATATAGGAAACACTTCATTCTTTATAAAACTTTCTATAATGCCTTATTTGAATGTTAATCTTATGTGCTTTCTAAAAAATGTTGTGAAATACCAAACTTATGGATTATCACTAGGTTATCAAGCATATATTAGTCTTTATCAGAATAAAATGAAATTTCATAACTGTGGCTATTACTTTGTTCTTGGTCCTTCACAGGGCCTGCTCCATCCCACCTTCCTTTCTGCTGCCTGATGTCTCAATGGCTTCTGAATGACTGTTCTAATAAATGATCTTAAAACAGTCCATAGGCTGGTTTCAGTTTATGCAATACTTCATCTCCTGCTATGGTAGCCATACCGGCCTTCATAATACCCTTAGGGGATTTGGAAATCAAAGTGAGCAGTGGAAGAACATGGCTATGAGAATTAAGACTCTTATTTCCTGTGACCATTCCCTCCCCACCCGCAAACACTTAGCCCAAAGTTTTGCACATACATTCATTACTTTAGGAATGAATATGACTGTAATACAACttttttctttatttttttttagacagggcctcactctgttgcccagactagagtgcagtggcataattgggtcactgtaacgttgaactcctgggctcacgcaattcttctacctcagcctcccaagtagctgaaactacaggtatgtaccaccatgcctggctaattttatttttttgtagagacggcgtctcgatatgttgcccaggctagtctcctggcctcaaacagtcttcctgattcagcttcccaagtgctgagattacaggtgtaagccactgcccccACCCAAAAAAATAATTCTGTAATGACCATCATTAAGATTTATGTACCACATGGAAATACATGTATGGAGCTGAATGCCATGGCTAGGAGAAACTACTATACTTTTGTTAAAAGCCAATGAGAggccgggcgcggtggctcacgcctgtaatcccagcactttgggaggccgaggcgggcggatcacgaggtcaggagatcgagaccatcctggctaacacggtgaaaccccgtctctactaaaaatacaaaaaaaaaaaaaaaaaattagccgggcatggtggcgggcgcctgtagtcccagctactcgggaggttgaggcaggagaatggtgtgaatccgggaggcggaggttgcagtgagctgagatcgtgccactgcactccagcctgggcgacagagggagactccgtctcaaaaaaaaaaGCCAGGGAGAACAGCACCTCAACTGATTTATTTTATAGAGTAAAAGTTATTTTGCTATACCTTTTGTAAGCAGCGTGTACTGTGGGAAATGCAAACTAGCAGTTGTTAGCACCATCCAGAAATTTCTGTCAGTTCCATTTCAAATAGTTTAAATACTGGCTCAAATCTCTAAACCCCACCCTATGGCTACTTTTCCCCCAGCTATATATAATGGCATTCTAGCAAGATATTTTGGATCCTCATAACTTGTGACAAAACTGCCCTATACTAACAACAAATCATTGTAATTATAGATCTCAAATTATGTTAAATTGCTATAGTTGCAACCAACAGCAAGAATTTGTATTTTAGAATATGTTGTGTCTTCTCATTGACCAaaaaataaaaataaaaataaaaataaaTCCTCAGGCCCTGATAAACTGTAGAAATAGCTTTTCTATCTTTGCAGTTAAAGATTTTCATCTTGGAAGTTATGGTTAAAAAATTTTTAAACAGTTAAAATAGTGTAGCTGTGCTTAAAGCTTCTGGTAAAAGCCAGTATGCTTTGTAGAGCCCTTATCCCCCTCCTGCTTTTTATTTGTTTTTAGCTCACTAAATAATATAAACACTGATTTTTCCATATATAGCACTGAATAAACTGTCATGCCTAAGTGTAAA

Publications

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