Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name CLTAP1
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:15688632-15689590  UCSC
Coordinates (T2T) chr8:15954884-15955842  UCSC
Coordinates (hg19) chr8:15546141-15547099  UCSC
Strand -
Parental Sequence NM_001833.4
Parental seq. overlap 770 bp
Parental seq. overlap (%) 70.6%
Genomic Region Intragenic (TUSC3)
Retrocopy Summary CLTAP1, located on chr8:15688632-15689590, is a retrocopy of the parental gene CLTA. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CLTA
Full Name clathrin light chain A
Also known as LCA
Coordinate chr9:36190855-36212059
Strand +
Gene summary Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, May 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CLTAP1
Gorilla Gorilla gorilla CLTAP1
Orangutan Pongo abelii CLTAP1
Gibbon Nomascus leucogenys CLTAP1
Green monkey Chlorocebus sabaeus CLTAP1
Crab-eating macaque Macaca fascicularis CLTAP1
Rhesus Macaca mulatta CLTAP1
Baboon Papio anubis CLTAP1
Golden snub-nosed monkey Rhinopithecus roxellana CLTAP1
Marmoset Callithrix jacchus CLTAP1
Opossum Monodelphis domestica CLTAP8
Bonobo Pan paniscus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CLTAP1
GAAATCTCCTAACAGCAGCCTCAACGTGTGCTTTTGTGCGTTATTCTGAGAATAAATTTCTATTTCAAACAGTTGGTGTCTGTGTCGTTAAATTGCACGACATGGCTGAGCAACATCCCTTCGGTGTCCCTGCTGGCACCCCTGGGGATCCTGTCCTGGGGAACGGAGTGGCTGGCGCCAGTGAAGAAGACCCAGCTGCGGCCTTCTTGGCACTGCAAGAGAGCAAGACTATGGGTATCAAGAACAACAAGGTCGCCTTCGACATCCTGGATGGTGTCACCCCCAGGCCCCAGCCACAAGGTGAACAGCTGGGAGTCCAGATGCTGTTGACGGAGTGATGATGGTGACTACTACCAGGAAAGTAATGGTCCAAGAGACAATTATGCAGCTATTTCACAAGTGGATCGATTCCCATCCAGCCTGAAAATATATGCAGATGCAAAGAAGAGAAAATGGAATGCTTAGCAGCCCTTGCTGCTTATTCTCCGAAGCAAGAAGCAGAGTGGAAAGAAAAAGCGATAAATGAGCTAGAAGAATGGCGTGCAAGACAAGACGAGCAGCTACAGAAAAGAAAGGCAAACTACAGGGCAGAAGATTTTGTAAATGACATTGACGAGTCATCCCCCTGCACTGGGTGGTAACAGGTGGCCCGGTTGTTTGACTGTAACCCCAAGTCAGCAAGCAGGGCAAAGAGGTCTCCTGTATGCACTCAGTCCTCAACTCCCTCAAGCAGGCGACCCCTGGTGCACTGACAAACCGCTCCTGGAAACACTACATCTGCAGTATCTTAATCCTACCTAGTGAAATTCTACAAAGTAACTGGATTAATTACGCTGAGTTCTTTTGGACCAAACTTTTTTGTGTTTAGAGCTGATCATTGTTTGTGATTGCACGTTTCCTTCAACTGTGTCCTCCCTGGCATACAg
>NM_001833.4
CCGCTTTACCCGTCTCCCTCCTGGCGCTTGTCCTCCTCTCCCAGTCGGCACCACAGCGGTGGCTGCCGGGCGTGGTGTCGGTGGGTCGGTTGGTTTTTGTCTCACCGTTGGTGTCCGTGCCGTTCAGTTGCCCGCCATGGCTGAGCTGGATCCGTTCGGCGCCCCTGCCGGCGCCCCTGGCGGTCCCGCGCTGGGGAACGGAGTGGCCGGCGCCGGCGAAGAAGACCCGGCTGCGGCCTTCTTGGCGCAGCAAGAGAGCGAGATTGCGGGCATCGAGAACGACGAGGCCTTCGCCATCCTGGACGGCGGCGCCCCCGGGCCCCAGCCGCACGGCGAGCCGCCGGGGGGTCCGGATGCTGTTGATGGAGTAATGAATGGTGAATACTACCAGGAAAGTAATGGTCCAACAGACAGTTATGCAGCTATTTCACAAGTGGATCGATTGCAGTCAGAGCCTGAAAGTATCCGTAAATGGAGAGAAGAACAAATGGAACGCTTGGAAGCCCTTGATGCCAATTCTCGGAAGCAAGAAGCAGAGTGGAAAGAAAAGGCAATAAAGGAGCTAGAAGAATGGTATGCAAGACAGGACGAGCAGCTACAGAAAACAAAAGCAAACAACAGGGCAGCAGAAGAAGCCTTTGTAAATGACATTGACGAGTCGTCCCCAGGCACTGAGTGGGAACGGGTGGCCCGGCTGTGTGACTTTAACCCCAAGTCTAGCAAGCAGGCCAAAGATGTCTCCCGCATGCGCTCAGTCCTCATCTCCCTCAAGCAGGCCCCGCTGGTGCACTGAAGAGCCACCCTGTGGAAACACTACATCTGCAATATCTTAATCCTACTCAGTGAAGCTCTTCACAGTCATTGGATTAATTATGTTGAGTTCTTTTGGACCAAACCTTTTTGTCTTTAGAGTTGTTCATTGTTTGTGATTGCATGTTTCCTTCCTTCAACTGTGTTCTCCCTGGCATTCAGagaggagggagaggaggaagaggaaggggagggaagCTTCCCAAGAGTAGCCTCAACCTGTGCTTCTGTGCATTATTCTGAGAATAAATTTCTGTTTCAAACTGTA

Publications

PMID - Link Title