Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name EPDR1P1
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:25141424-25141807  UCSC
Coordinates (T2T) chr8:25420288-25420671  UCSC
Coordinates (hg19) chr8:24998939-24999322  UCSC
Strand -
Parental Sequence NM_017549.5
Parental seq. overlap 331 bp
Parental seq. overlap (%) 13.2%
Genomic Region Intergenic
Retrocopy Summary EPDR1P1, located on chr8:25141424-25141807, is a retrocopy of the parental gene EPDR1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name EPDR1
Full Name ependymin related 1
Also known as EPDR|MERP-1|MERP1|UCC1
Coordinate chr7:37920640-37951936
Strand +
Gene summary The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Aug 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes EPDR1P1
Bonobo Pan paniscus EPDR1P1
Gorilla Gorilla gorilla EPDR1P1
Orangutan Pongo abelii EPDR1P1
Gibbon Nomascus leucogenys EPDR1P1
Green monkey Chlorocebus sabaeus EPDR1P1
Crab-eating macaque Macaca fascicularis EPDR1P1
Rhesus Macaca mulatta EPDR1P1
Baboon Papio anubis EPDR1P1
Golden snub-nosed monkey Rhinopithecus roxellana EPDR1P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>EPDR1P1
CCCTGCAAGAGATTATTTGAATATATTTTGCTCCGTAAGGATGGAGTGATGTTTCAGACTGAGAAAGCTACCAAGCAGTGCTCAAAGATGACTCTGACAGAGCCCTAGGAGCCTCCTGACATTCCACAGAACTCCACCTTTGAAGATCAATACTCTACTGGGGGCCCCCAGGTGCAGACCACTGTCCAGGTGTCATCGGACAGAAAGTCAGCCAGATCCTAGGAAATCTGGATTGGCATCTATACAGTCAAGGATTGTTGCCCTGTCCGGGAAGCATTTATCAAAAATTACAGTGTGATATTGTCCGTGTGATTTTTTGACACATGGCTGGGCTTTAAAGATCCCTTGGTGTTTACCCCTCCGAGCACATGCCAGATGGCCCAG
>NM_017549.5
agtgaaaaccgaagcggcagaaggcagtggcagcaggcagtggcagcaggcagtgGCCCAGGCAGAAATAGCTCCCGCGCGATTCACTGGAGCCTTCCCCGGGCCCTGGTCCCGGCTACCGGGACTCGCGCGTCCGGATCTCAAAAGCGGCAGAGGCCACCGAAGGGACAGGAAGCACTTTGGTCCAGACCACACTCCCGGCACAGTGCGGAAAGAGCCGGCGGGAGCCACTCTGATCCCGGACGCCTCAGCGCCCCCTTGGGCTTGGGCTTGCCCTCGGGCCGGGGAAGGCTGACCGCGATGCCAGGACGCGCTCCCCTCCGCACCGTCCCGGGCGCCCTGGGTGCCTGGCTGCTGGGCGGCCTCTGGGCCTGGACCCTGTGCGGCCTGTGCAGCCTGGGGGCGGTGGGAGCCCCGCGCCCGTGCCAGGCGCCGCAGCAGTGGGAGGGGCGCCAGGTTATGTACCAGCAAAGTAGCGGGCGCAACAGCCGCGCCCTGCTCTCCTACGACGGGCTCAACCAGCGCGTGCGGGTGCTGGACGAGAGGAAGGCGCTGATCCCCTGCAAGAGATTATTTGAATATATTTTGCTGTATAAGGATGGAGTGATGTTTCAGATTGACCAAGCCACCAAGCAGTGCTCAAAGATGACCCTGACACAGCCCTGGGATCCTCTTGACATTCCTCAAAACTCCACCTTTGAAGACCAGTACTCCATCGGGGGGCCTCAGGAGCAGATCACCGTCCAGGAGTGGTCGGACAGAAAGTCAGCTAGATCCTATGAAACCTGGATTGGCATCTATACAGTCAAGGATTGCTATCCTGTCCAGGAAACCTTTACCATAAACTACAGTGTGATATTGTCTACGCGGTTTTTTGACATCCAGCTGGGTATTAAAGACCCCTCGGTGTTTACCCCTCCAAGCACGTGCCAGATGGCCCAACTGGAGAAGATGAGCGAAGACTGCTCCTGGTGAGCCTGTGCATAGGGAAGCGGCAGCATCGGATGTCAGCCCCCTGCGGCCCCAGCTGGAGATGGATATGAGACTAGTCAAGATGTGAATGCTAATTGGAGAGAAATATAATTTTAGGAAGATGCACATTGATGTGGGGTTTTGATGTGTCTGATTTTGACTACTCAAGCTCTGTTTACAGAAGAAAATTGAATGGCGAGGGTGTGGCCATATGAACTGACTAGATGGCTAATATGGACACTTTGGGTATTTCTAATGCCTGTTCAGGGCTGGTTTTCTGCATGCACGGGTATACACATAATGCAGTGCCATGCACATAGGGAAGGGTCAGTAAGAGAAGTTTGCCTTGGCAGCAagtatttattgttgacattattcagaattagtgataataaaaagcagagtgattttggtcaattttattattaattcttaaattccctgcagagaatgccccctttattgctgcaccagggttggcattgctcccactgagccctactcCACCCTGTCCCTGCACTCCCTTGGTTGCCAAAAAAATGATAACTTAAATCCCTTCCAGACTTAAGAATTTTATGGCATGGCCCAATTGATATAAACATTTAGAAGGAAATGAAAAGCTAAAATAGGAAGTAATTATTCCTCTAAAGAAACATTTTGAGCAAGGCAGTTTAGAGAATCCTAATGTCTACACTGGCATAGCACGAGCCATGTAAGCTTCTTTTTTTTCTATGCAAGAGTATTGATGTATGTGCTGAATCTTCACAGACTTGTCAATACACAGGCAGTATTCTAAAATAGCACTGAACAGGGAGTCAGGAGACTATTGTCTCCTAAACCCAGGACTAGAGTTCCCTcgtactgtcactcctttggtcattaaatgcactgggcttgcccgcactttggccttcctagaacactgcttcataacctctctgtctgacttctgcatctccttccaggtcagctcattcacaagagttgctcccaagcctggatgagttgcaccttgcatcttgagcatgcatttctcacaataattattaagctgtgtgataatttctgctttcaggacactcatccattatcttggctgtgagctccttgggtacgggtaccttgtatgtttacttttatatccctagcacaaagcaagtgcctggcacatagtcagtgccctaagtattcgtagagtgaagaatGCCAGCCTCTCTTGTCCCTGGTTTCCTTATGTGTTGAATGTGGTTGAGTTTGTCCATTGCTAGGGAGAGACTTCCAGTAATAAAATTTACTATTCTAGATGCTTCTACTGTTATGTTTTATCTGCCCATTTATCTTTCTTAGTTACCAGGAGAAATGTGTGACACCTATATTATAATGAAAACAATCTCATTACTTATAGTTTATCTATATTAAACAAATTTAATTGCATTTTAAAGCATTCTTTGATACTGTTGCTTTTGCAATAAATATGGATAATCTTGGTTATAAGGGAGTTAAAACAATGCTGTAATAAATAAAGTGcttcatgtgatcaaaa

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