Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RSL24D1P14
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:5071292-5072920  UCSC
Coordinates (T2T) chr8:4824078-4825711  UCSC
Coordinates (hg19) chr8:4928814-4930442  UCSC
Strand -
Parental Sequence NM_016304.3
Parental seq. overlap 1248 bp
Parental seq. overlap (%) 58.2%
Genomic Region Intergenic
Retrocopy Summary RSL24D1P14, located on chr8:5071292-5072920, is a retrocopy of the parental gene RSL24D1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RSL24D1
Full Name ribosomal L24 domain containing 1
Also known as C15orf15|HRP-L30-iso|L30|RLP24|RPL24|RPL24L|TVAS3
Coordinate chr15:55180806-55196941
Strand -
Gene summary This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the biogenesis of the 60S ribosomal subunit. The precise function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals and has multiple pseudogenes. [provided by RefSeq, Jul 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RSL24D1P6
Bonobo Pan paniscus RSL24D1P7
Gorilla Gorilla gorilla RSL24D1P7
Orangutan Pongo abelii RSL24D1P6
Gibbon Nomascus leucogenys RSL24D1P4
Green monkey Chlorocebus sabaeus RSL24D1P8
Crab-eating macaque Macaca fascicularis RSL24D1P10
Rhesus Macaca mulatta RSL24D1P10
Baboon Papio anubis LOC101012615P9
Golden snub-nosed monkey Rhinopithecus roxellana RSL24D1P13
Marmoset Callithrix jacchus RSL24D1P13
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RSL24D1P14
ACTTCCTCTCAAGCTTGGCATTTGGTTGGTGGGGACCCAGGCGTGTTCAACATGCTTATCGAGAAGTATTATTTCCGTTCGGGGCCCATCTACCCTGGCCATGGCATGATGTTCGTCTGCAGTGATTGCAAGCTGTTCAGATTTTGTCAAGCTTAGTGTTATAAGAAACTTTAAAAAGAAGTGCAATCCTCGCAAAGTTGGTGGACCAAAGCATTTCGGAAAGCAGCTGGTAAAGATCTTACAGTGGATAATTCATTTGAATTTGCAAGACGTAGAATCTGAAAAACCTATCAAATACCAGCGAGAGCTATGGAATAAATCTATGGATGCAATGAAGAGAGTTGAAGAGATCAAACAGAAAAGCCAAGCTAAATTTATAATGAACAGATGGAAGAAAAATAAAGAGCTACAGAAAGTTTAGGATATCAAAGAAGTCAAGCAAAACATCCATCTTCTCCAAACCCCTCTTGCAGGCAAATGGTAACAGGTGGAAGAGAAAATGGTACAGCAGTTACAAAAGGATGTGGAGATAGAAGATGTTTCTTACAAATCTCTGAAAATGCCCTTTGGAGACTTGGAACTGGTAAATTATTAAATTTACCAGTTTACTAAACTTTCACTAAACCACTTGCACTAACAAAGACTATTCTAGGAATGTGAAGGATACATTTTTTTGTAAATGAAATGAGATAAGATCATCCAAAATGAAATTGCTACATGTCTACTATGGGAATAGATTCCATATTCCATATTTTGAATTAGACGAAGTTTTGTTTATTTAAAAATAATCAAATTGTGTTTAGTCAGATGATTATCTTCTAAAGTTAAAAAACTTTATTTTTTACATAAGGTCACTTAAATGAAAAGTGATTACAATATATGTCTCCTACATTGCCATGTACAAAACATCAGATATTACGGGTGTTAGATTGCATTTCAGTGTTAAATCTTCACTGATAGATGTACTTATCTATCAGTACATCTGATACTTATGATTTAAGTAAATCATAAAAATTCTACTTATCACTATAGAAATGAATTGTGGATGTAAAATTGTTATGTCATTTGGATAACGGCACTGGCATCATTTGTATAATAACTAATGGCAAAAATTCATGGCTAGTGATGTATAAAATAAAATCTTCTTTGCAGTAAAATATTCCCTTTATTAATGTTGTAGAAGGGAGGATACAACAAGGAATTAACAATTTGTATGACAGCGTCAAATATTATTTTGATTTTAGTATTTCCTGTTTTGGTTTATTTGCAGCTTAGAAGAGCATAATGACATTGTTTGATGAAGCCTCATTATGCTGGACTGTTTTGACCTGGTTTAACCCTTCTGATAGGGAGTTGTGGATGTTGGGGTGAGAACTGAATAATCTTTGCCTGGAGTGACATTACACTCTAGAATTTCCACTTTGGAGAATATTCAGTTCTAACTTGTGATTTCTGGTGGAACCAACTTTATTTTTCCAGCCTAGCAATGATCTAGAAGCAGAGGAATCCCAGTGCCTTTTAAAAGTTATTATGTGGTTTTTCTTTTAGAAAGCATCTGTTTTTAGAAAGTAGAATTTATGGGTAAAACACCTGTTCATTATTTGCACATAAAATCATTTAAAAAGTAAA
>NM_016304.3
ACTTCCTCTCAAGCTTGGCGTTTGTTTGGTGGGGTTACACGCGGGTTCAACATGCGTATCGAAAAGTGTTATTTCTGTTCGGGGCCCATCTATCCTGGACACGGCATGATGTTCGTCCGCAACGATTGCAAGGTGTTCAGATTTTGCAAATCTAAATGTCATAAAAACTTTAAAAAGAAGCGCAATCCTCGCAAAGTTAGGTGGACCAAAGCATTCCGGAAAGCAGCTGGTAAAGAGCTTACAGTGGATAATTCATTTGAATTTGAAAAACGTAGAAATGAACCTATCAAATACCAGCGAGAGCTATGGAATAAAACTATTGATGCGATGAAGAGAGTTGAAGAAATCAAACAGAAGCGCCAAGCTAAATTTATAATGAACAGATTGAAGAAAAATAAAGAGCTACAGAAAGTTCAGGATATCAAAGAAGTCAAGCAAAACATCCATCTTATCCGAGCCCCTCTTGCAGGCAAAGGGAAACAGTTGGAAGAGAAAATGGTACAGCAGTTACAAGAGGATGTGGACATGGAAGATGCTCCTTAAAAATCTCTGTAACCATTTCTTTTATGTACATTTGAAAATGCCCTTTGGATACTTGGAACTGCTAAATTATTTTATTTTTTACATAAGGTCACTTAAATGAAAAGCGATTAAAAGACATCTTTCCTGCATTGCCATCTACATAATATCAGATATTACGGATGTTAGATTGCATCTCAGTGTTAAATCTTTACTGATAGATGTACTTAAGTAAATCATGAAAATTCTACTTGTAACTATAGAAGTGAATTGTGGACGTAAAATGGTTGTGCTATTTGGATAATGGCACTAGGCAGCATTTGTATAGTAACTAATGGCAAAAATTCATGGCTAGTGATGTATAAAATAAAATATTCTTTGCAGTAAAATATTCCCTTTGTTAATGTTATAGAAGGGGGGATACAAAAAGGAACTAACAATTTGTATGGCAGTGTCAGATATTTTTATTTTAGTATTTCCTGTTTTGGTTTATTTGCATCTTAGAAGAGCATAATGACATTGTTTGATGAAGCCTAATTATGCTGGACTGTTTTGACCTGGTTTAACCCTTCTGATAGGTAGTTGTGGATGCTGGGGATGAGAACTGAATAATCTTTGCCTGGAGTGACACTACACTCTAGAATTTCCACTTTGGAGAATACTCAGTTCCAACTTGTGATTCCTGATAGAACAGACTTTACTTTTCTAGCCCAGCATTGATCTAGAAGCAGAGGAATCCCAGCGCCTTTTAAAAGTTGTTATGTGGTTTTCTTTTAAAAAGCTCCTGTTTTTGGAAAGTAGAATTTATGGGTACAACGTATGTTCATTATTTGTACATAAAATAAAACCATTTAAAAAGTAATGCTGATATTTATTCTTTAAAGGCACTAAACAAAGATATGAAATATTGATGACCTGGAAGAAGAAATCTTCCTCCACACATCCCATTTAAGTAGGAGATACATTTAATTAAAGAGAAATAGATACTTAATACTTAATGTTTTGTGTTTTTACATTGTTTACAGTTTTAAGTATGTTAAATACATTAAGTAACGATCAGTTTGCATAATGGTTTTTTTAGGGTAGAGTTTAAAATCAGTAATTCTTAGCCTTACATAATTATAAAGTAATGGCTCATTTTTTGTTTCAGTATTAGATAGTAAAACTAAGGCTGTAGACCAGTCCCTGGACCAAGTGTTAGGAGACCTGAGTTCCAATGTGGTTTTGCCTGGGTATTCTTATTTGTAAATAATATTATTGATTGAAGATTAGGGGAAATGATACATGTGAGGAAAGACATTTGTAAAATTTCTTGGGTTTTTACTACATACCGTATTCATTTTTTAAAGAAATAAACATTTTGAAAGTTA

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