Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SRPK2P2
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:62864196-62866761  UCSC
Coordinates (T2T) chr8:63288633-63291195  UCSC
Coordinates (hg19) chr8:63776755-63779320  UCSC
Strand +
Parental Sequence NM_001350739.2
Parental seq. overlap 2376 bp
Parental seq. overlap (%) 62.9%
Genomic Region Intragenic (NKAIN3)
Retrocopy Summary SRPK2P2, located on chr8:62864196-62866761, is a retrocopy of the parental gene SRPK2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SRPK2
Full Name SRSF protein kinase 2
Also known as SFRSK2
Coordinate chr7:105113601-105399363
Strand -
Gene summary Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including nucleic acid metabolic process; peptidyl-serine phosphorylation; and regulation of viral genome replication. Located in chromatin; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SRPK2P2
Bonobo Pan paniscus SRPK2P2
Gorilla Gorilla gorilla SRPK2P2
Orangutan Pongo abelii SRPK2P2
Gibbon Nomascus leucogenys SRPK2P2
Green monkey Chlorocebus sabaeus SRPK2P1
Crab-eating macaque Macaca fascicularis SRPK2P2
Rhesus Macaca mulatta SRPK2P2
Baboon Papio anubis SRPK2P2
Golden snub-nosed monkey Rhinopithecus roxellana SRPK2P2
Marmoset Callithrix jacchus SRPK2P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SRPK2P2
CGGATGGCGAATACTGCGCAGAAGTGAAACTAAAAACAGCAGGATTAGAGGAGGCGGCCGAGGCAGACGGCAAAGGACAATGCTGAAGCTGAGGACCAGGAAGAGAAAGAAGACCCTGAGAAAGAAAACATTGAGAAAGAAGATGATGTAGATCAGGAACTTGCGAACATAGACCCTACGTGGATAGAATCACCTAAAACCAATGGCCATCTTGAAAATGGCCCATTCTTACTGGAGCAGCAACTGGACGATGAAGAGGATAATGAAGAAGACCGCCCAAATACTGAGGAATATAATCTTGATGAGCCAAATGCAGAAAGTGATTACACATATAACAGCTCCTATGAACAATTCAATAGTGAATTGCCAAATGTATGGCATAAAATTCCCGAGTCACAGTTTCCAGAGTTTTCCACCTCGTTGTTTTCTGGATCCTTAGAACCTGTGGCCTGCAGCTCTGTGCTTTCTGAGGGATCACCACTTACTGACAGAAGCAGGACGGTTTCAGCCTCCAGTACTGGGGATTTGCCAAAAGCAAAAACCCGGGAGGCTGACTTGTTGATGAATCCCCTGGATACACGGAATGCAGATAAAATTAGAGTAGAAATTGCTGACCTGGGAAATGCTTGTTGGGCGCATAAACACTTCACGGAAGACATCCAGATGAGTCAATACCGTTCCATAGAGGTTTTAATAGGAGAGGGATACAGCACCCCTGCGGACATCTGGAGCGCGGCGTGTATGGCATTTGAGCTGGCAATGGGCGATTATTTGTTTGAACCACATTCTGGGGAAGACTATTCCAGAGACGAAGATCACATAGCATTGATCATTGAACTGCTGGGGAGAGTCCGGTTTACTGACCGTTTTCTTCTGGAAAAAAATACGCTATGTTGGGGAAATATTTCGAGGAGTTTTTCACCAGAAAAGGAGAACTGCGACATCACCAAGCTGAAACCCTGGTGCCCTTTTGATGTACTTGTGGAGAAGTATGGCTGGCCCCATGAAGATGCTGCATAGTTTACAGATTTCCTGATCCCGATGTTAGAAATGGTTCCAGAAAAAACGATCCTCAGCTGGCGAATGCCTTCAGCATCCTTGGTTGAATTCTTACCAAATTCTACCAATACTGCATTCTGAGCTAGCAAGTGTTCCCAGAGCGTTGGACATAAACGGTGACTCTCATTCTTTAACAGGATTACAAGTGAGCTGGCTTCATCCTCAGACATTTATTTTGCTTTGAAGTACTGTTGTTTGACATTTTGCTTTTTGTGCACTCTGATCCTGGGGAAGAGCAGTCTTTTGACTTCCCTTAGTGGTTTACTGACCGTTTTCTTCTGGAAACAATAACGTGTCTCTAAGCATTGTTTCTTGTGTTGTGTGACATGCAAATGTCATTTTTTTAATGAGAAATACTTTCCCCTTTGTGTTTTGGCAGGGTTTGTGACTATCTATTTATGAAAAATAAATTTTAGCTGAGTACTATATTATTGATAACCTTAAGAAATTATCAAGTTGGAACCAAGAAATAGCAAGGAAATATGCAATGTTATCTTCTGGCAAAGGGACATCATTCCTGTATTATAGTGTATGTAAACACACACTGTAAATGTTACTTTCCATTAAACATGGGAGGGGGGCTCAAATTTCAGAAAAGCTACCAAGTCTTGAGTTCTATGTAGCATATGTTGCATGTAGCCGACTTTAACTGCTTCTAGGAGTTGTGCAAGCTTTTCATTCCATAACAGTCCTTTCACATTGGATTTTTAAAAAAGTGGCTCCGGGTTGTAAGATATCATTCTCTATGTGGCACTTTAAAGGAAGAAAAAATAGGCTTCTCATTCTAAAATATGCATAATAATTTAGCAGTCCCATTTGTATTTTTGCATATTTTTAAAAGTATTTTTAAAGAAAAAGAGGGATTTCACTTTAAAAATGTAAAGGCTTAGTACCATGTCATAATGCCTCCTCTGGGCACTGTAACTTAAGCTCCACATAGATTAAATTGGAAAAGAGAAATGTGTTCATTGTGTCGAATGAAAAAATACATATATTTTCGAAAAAGCATGATCATGCTTGTCTAGAACACAAGGTATGGTATATACAATTTGCAGTGCAGTGGGCAGAATTCTCCTCACAGCTCAAAGGTAACAGTGATCATATTCATTCCGTAGGTAGCTTTATGTGTGGCTACAACAAATTTTAGCAGCTTTTTTATTGTCTTTCCATGAAATGAAGTTGAGAAAATGATTTTCCCTTTGCAAGTTGCACACAGTTTTGTTTATGCATTTCCTTAAAATTAATTGTAGAATCCAAGACACAAACCACAGGTGGCAATACAATTTTAGAATGTAACATATAGAGGTATATTTAGCCTGTTTTAGAAGTCAGTGGATTCAATGTCTTTTTACTTTAAATTTTACATTAATTAAGGTGCCTCATTTTTTACTTTGTCCATTAACATTTATCCATATGCCTTTGCAATAACTAGATTGTGAAAAGCTAACAAGTGTTGTAACAATAATCCATTGTTTGAGGTGTTTGCGGTTGTCTTAAAAATTAAAGT
>NM_001350739.2
AGGCCTGATGCCTCTGGAGCTTTTTCCCTTTATAGCACCATTGAATCCCAGTCCTAACAGAAGTACTGCGAATCTTGTGGCCTCATTCTGAACAAAAGGGATTAGAGAAGAAAAATCTCTTGATATAAGGCTTGAAAGCAAGGGCAGGCAATCTTGGTTGTGAATATTTTCTGATTTTTCCAGAAATCAAGCAGAAGATTGAGCTGCTGATGTCAGTTAACTCTGAGAAGTCGTCCTCTTCAGAAAGGCCGGAGCCTCAACAGAAAGCTCCTTTAGTTcctcctcctccaccgccaccaccaccaccaccgccaccTTTGCCAGACCCCACACCCCCGGAGCCAGAGGAGGAGATCCTGGGATCAGATGATGAGGAGCAAGAGGACCCTGCGGACTACTGCAAAGGTGGATATCATCCAGTGAAAATTGGAGACCTCTTCAATGGCCGGTATCATGTTATTAGAAAGCTTGGATGGGGGCACTTCTCTACTGTCTGGCTGTGCTGGGATATGCAGGGGAAAAGATTTGTTGCAATGAAAGTTGTAAAAAGTGCCCAGCATTATACGGAGACAGCCTTGGATGAAATAAAATTGCTCAAATGTGTTCGAGAAAGTGATCCCAGTGACCCAAACAAAGACATGGTGGTCCAGCTCATTGACGACTTCAAGATTTCAGGCATGAATGGGATACATGTCTGCATGGTCTTCGAAGTACTTGGCCACCATCTCCTCAAGTGGATCATCAAATCCAACTATCAAGGCCTCCCAGTACGTTGTGTGAAGAGTATCATTCGACAGGTCCTTCAAGGGTTAGATTACTTACACAGTAAGTGCAAGATCATTCATACTGACATAAAGCCGGAAAATATCTTGATGTGTGTGGATGATGCATATGTGAGAAGAATGGCAGCTGAGGCCACTGAGTGGCAGAAAGCAGGTGCTCCTCCTCCTTCAGGGTCTGCAGTGAGTACGGCTCCACAGCAGAAACCTATAGGAAAAATATCTaaaaacaaaaagaaaaaactgaaaaagaaacagaaGAGGCAGGCTGAGTTATTGGAGAAGCGCCTGCAGGAGATAGAAGAATTGGAGCGAGAAGCTGAAAGGAAAATAATAGAAGAAAACATCACCTCAGCTGCACCTTCCAATGACCAGGATGGCGAATACTGCCCAGAGGTGAAACTAAAAACAACAGGATTAGAGGAGGCGGCTGAGGCAGAGACTGCAAAGGACAATGgtgaagctgaggaccaggaagagaaagaagatgctgagaaagaaaacattgaaaaagatgaagatgaTGTAGATCAGGAACTTGCGAACATAGACCCTACGTGGATAGAATCACCTAAAACCAATGGCCATATTGAGAATGGCCCATTCTCACTGGAGCAGCAACTGGACGATGAAGATGATGATGAAGAAGACTGCCCAAATCCTGAGGAATATAATCTTGATGAGCCAAATGCAGAAAGTGATTACACATATAGCAGCTCCTATGAACAATTCAATGGTGAATTGCCAAATGGACGACATAAAATTCCCGAGTCACAGTTCCCAGAGTTTTCCACCTCGTTGTTCTCTGGATCCTTAGAACCTGTGGCCTGCGGCTCTGTGCTTTCTGAGGGATCACCACTTACTGAGCAAGAGGAGAGCAGTCCATCCCATGACAGAAGCAGAACGGTTTCAGCCTCCAGTACTGGGGATTTGCCAAAAGCAAAAACCCGGGCAGCTGACTTGTTGGTGAATCCCCTGGATCCGCGGAATGCAGATAAAATTAGAGTAAAAATTGCTGACCTGGGAAATGCTTGTTGGGTGCATAAACACTTCACGGAAGACATCCAGACGCGTCAGTACCGCTCCATAGAGGTTTTAATAGGAGCGGGGTACAGCACCCCTGCGGACATCTGGAGCACGGCGTGTATGGCATTTGAGCTGGCAACGGGAGATTATTTGTTTGAACCACATTCTGGGGAAGACTATTCCAGAGACGAAGATCACATAGCATTGATCATTGAACTGCTGGGGAAAGTCCCTCGAAAATACGCTATGTTGGGGAAATACTCCAAGGAGTTTTTCACCAGAAAAGGAGAACTGCGACACATCACCAAGCTGAAGCCCTGGAGCCTCTTTGATGTACTTGTGGAAAAGTATGGCTGGCCCCATGAAGATGCTGCACAGTTTACAGATTTCCTGATCCCGATGTTAGAAATGGTTCCAGAAAAACGAGCCTCAGCTGGCGAATGCCTTCGGCATCCTTGGTTGAATTCTTAGCAAATTCTACCAATATTGCATTCTGAGCTAGCAAATGTTCCCAGTACATTGGACCTAAACGGTGACTCTCATTCTTTAACAGGATTACAAGTGAGCTGGCTTCATCCTCAGACCTTTATTTTGCTTTGAGGTACTGTTGTTTGACATTTTGCTTTTTGTGCACTGTGATCCTGGGGAAGGGTAGTCTTTTGTCTTCAGCTAAGTAGTTTACTGACCATTTTCTTCTGGAAACAATAACATGTCTCTAAGCATTGTTTCTTGTGTTGTGTGACATTCAAATGTCATTTTTTTGAATGAAAAATACTTTCCCCTTTGTGTTTTGGCAGGTTTTGTAACTATTTATGAAGAAATATTTTAGCTGAGTACTATATAATTTACAATCTTAAGAAATTATCAAGTTGGAACCAAGAAATAGCAAGGAAATGTACAATTTTATCTTCTGGCAAAGGGACATCATTCCTGTATTATAGTGTATGTAAATGCACCCTGTAAATGTTACTTTCCATTAAATATGGGAGGGGGACTCAAATTTCAGAAAAGCTACCAAGTCTTGAGTGCTTTGTAGCCTATGTTGCATGTAGCGGACTTTAACTGCTCCAAGGAGTTGTGCAAACTTTTCATTCCATAACAGTCTTTTCACATTGGATTTTAAACAAAGTGGCTCTGGGTTATAAGATGTCATTCTCTATATGGCACTTTAAAGGAAGAAAAGATATGTTTCTCATTCTAAAATATGCATTATAATTTAGCAGTCCCATTTGTGATTTTGCATATTTTTAAAAGTACTTTTAAAGAAGAGCAATTTCCCTTTAAAAATGTGATGGCTCAGTACCATGTCATGTTGCCTCCTCTGGGCGCTGTAAGTTAAGCTCTACATAGATTAAATTGGAGAAACGTGTTAATTGTGTGGAATGAAAAAATACATATATTTTTGGAAAAGCATGATCATGCTTGTCTAGAACACAAGGTATGGTATATACAATTTGCAGTGCAGTGGGCAGAATACTTCTCACAGCTCAAAGATAACAGTGATCACATTCATTCCATAGGTAGCTTTACGTGTGGCTACAACAAATTTTACTAGCTTTTTCATTGTCTTTCCATGAAACGAAGTTGAGAAAATGATTTTCCCTTTGCAGGTTGCACACAGTTTTGTTTATGCATTTCCTTAAAATTAATTGTAGACTCCAGGATACAAACCATAGTAGGCAATACAATTTTAGAATGTAATATATAGAGGTATATTTAGCCTCTTTTAGAAGTCAGTGGATTGAATGTCTTTTTATTTTAAATTTTACATTCATTAAGGTGCCTCGTTTTTGACTTTGTCCATTAACATTTATCCATATGCCTTTGCAATAACTAGATTGTGAAAAGCTAACAAGTGTTGTAACAATAATCCATTGTTTGAGGTGCTTGCAGTTGTCTTAAAAATTAAAGTGTTTTGGTTTTTTTTTTTCCAGA

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