Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CHRAC1P2
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:73511320-73511648  UCSC
Coordinates (T2T) chr8:73941239-73941567  UCSC
Coordinates (hg19) chr8:74423555-74423883  UCSC
Strand -
Parental Sequence NM_017444.6
Parental seq. overlap 270 bp
Parental seq. overlap (%) 10.9%
Genomic Region Intragenic (STAU2)
Retrocopy Summary CHRAC1P2, located on chr8:73511320-73511648, is a retrocopy of the parental gene CHRAC1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CHRAC1
Full Name chromatin accessibility complex subunit 1
Also known as CHARC1|CHARC15|CHRAC-1|CHRAC-15|CHRAC15|YCL1
Coordinate chr8:140511322-140517154
Strand +
Gene summary CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CHRAC1P2
Bonobo Pan paniscus CHRAC1P2
Gorilla Gorilla gorilla CHRAC1P2
Orangutan Pongo abelii CHRAC1P2
Mouse lemur Microcebus murinus CHRAC1P1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CHRAC1P2
GGACGTGGTTGTGGGCAAAGACAAGTGCAGGGAGCAGTGGCTTCTCTTGCTGTCCCTGTCCCACATCTGGTCATCATGAAGAGTTCTCCCATGGTGTTGTGCATCAACCTCGAGGTGCTCCTGGCCAAGGCCACACAACTCTTTGTTAAGTCTCTAACCATCTATTCCTACGGTCATGGCAGTAGAAAGAAGAAAGCACTAACAGTAATTTAGCAAATACAGCAGAGGAATCAGAAATTTTTCAGTTTCTTGAAGGTGTATTATTGCCAAAGAAGGTTTCCACTAGTAAATACCTGAAAGTTCTTAAAGAGGAAAGGAGGGAAGAAGAA
>NM_017444.6
CTCACGGAGCTCGTAGTTTCCCGGACGGGCCGCTCCCGGCCTCGCGGCCTCGCCTCCCCACACTACAACTCCCACGGGGCAGCGGGCGCGGCTCCCCGTACCCACCAGCTGGCCGGGCAGGGCAGCCACTTCGCGGTCGGGCCCGCCGGCTGCGGGCACCCGCGCGACGGGCGGGAAGATGGCGGACGTGGTCGTGGGTAAAGACAAGGGCGGGGAGCAGCGGCTCATCTCGCTGCCTCTATCCCGCATCCGGGTCATCATGAAGAGCTCCCCCGAGGTGTCCAGCATCAACCAGGAGGCGTTGGTGCTCACGGCCAAGGCCACGGAGCTCTTTGTTCAATGCCTAGCCACCTATTCCTACAGACACGGCAGTGGAAAGGAAAAGAAAGTACTGACTTACAGTGATTTAGCAAACACTGCACAGCAATCAGAAACTTTTCAGTTTCTTGCAGATATATTACCAAAGAAGATTTTAGCTAGTAAATACCTGAAAATGCTTAAAGAGGAAAAGAGGGAAGAAgatgaggagaatgacaatgataatgaaagtgaccatgatGAAGCTGACTCCTAAACCAAAAGTGCTTTAAAAACCAGCCTGGCGAGGACAGCCCTGGACCCACTCCACTGTCTCTAAGTAAACACAGCACTGCCCGCTTTTAGCGTCTTCACTTCTTCACAGAGTTCCAGTGTGTGGTATTCTTTCGAGGTATTCTTTCCAGGCCGAGATTGAGCACCTCATGTACCTACGCCACAGACAGCCAGAGGGAAAGCGACCCAGACAGCAGCCCCTCCTCGACAGGCCCACCCTGCAGCTCAGGCACCAAGAAAACAGCCGATACTGGCAGCCATTGCAGCTCCAAACTGCAGAGGCAAGGCCAATTTTAACTTTTCAATTTACAGTCGATTTTGAAGAGCTTCTACATATCGGTTATGTAAATTCATATATGTATATTTTGGAATCAGTTCTTATAAACAGCTCGATTCAGTTTTAGCTAAATTTATAGTTTAGGTAGTATGTTACATTTGAATTTTTGTCTTAAGAAAAGTTGACTGTTCAGATATTTTTCTACTGTAAAGAAATATACTTTTCTATTAAAGATCTGTACATATTTTTACAGTAAAATGCTTTATGGAACTAGTTTTAGAGCCCTCTATGGCTTTAAGGCCTTGCTTACTGCCTGCAAATTTTGAGAAATTTAAAAATAAGCATTCTAACACTTTTATTCCCACAGAAAAATTCCAAGTCAAATTATCAAATCAAATACAAAAATAAGTCTTACCTCTTGTATAAGCATGTTGTACTAAAAAAAAATTTTGAAACATTTTGTATATTGGAGATCTCTCTCATCTTACTGTTCTTTGCTTTAAATTCCTGGCACTTCTTTTTACTGTCTATAAGAGAAAACCTATCATAAGCCCAATTTTTTTTTTCCACTTAGGGTAAATGTTTGGCTCCTCTCAtttcattatctttttttttttttttttaaagacagattctcactcagttgcccaggctggattgcggtggcgctgtctcagctcactgcaacctccgcctcccaggttcaagtgattctcctgcctcatcctcctgagtagctgggattacaggcgtgtgccaccatgcccaacctatttttgtattttttagtagagacggggttcaccatgttggccaggcttgtctcaaactcctaacctcaactgatccacctgcctcagcctcccaaagtgccgccgggattacaggcgtgagccaccatgcctggccTTCATTATCTCTTTTTTAAAAATGAAAAAGTTtataatttacattcagtaaaatcaccctttttagtgtctagtctgtgaattttgacaaatgcatggttttgtaaccaatcgataggacagttctgccacccaggacattcccctctgttcctctgttcctctcttctcctgccccctagcaaccactggtgttttctgtccctcttgttcattgacatttattttaaaataaaatattttaaaatctactttttggtgtacagttctgagttttggcaaatgcagtcaagtcactaccaccaccacaattaacagctatatcaccctccagtaaattccctgtggtcagctccttccccaccttttaccgtggcaaccgtcaagctattctctgtccctataccaggtgtcatcaaatttttttctggaaagggccatgcagtaaatagttcaagctttgtgggcttttatagtctctgttgctgctgctgaactcagctgttgtagcacgaaagcagccaggtaattactagatgaaggaatgcaggtggctgtgtttcaatagagctttatttctgcaaactgaaacttgagttttgtgtaattttcatgtgtcatgaaatactgttttctccaaccatttaataatgtaaatacttgctagcttatgtgccattaaaaaatgacttgatttggcttaca

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