Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name REXO1L8P
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:85642791-85643987  UCSC
Coordinates (T2T) chr8:86081557-86082753  UCSC
Coordinates (hg19) chr8:86555020-86556216  UCSC
Strand -
Parental Sequence NM_020695.4
Parental seq. overlap 997 bp
Parental seq. overlap (%) 21.6%
Genomic Region Intergenic
Retrocopy Summary REXO1L8P, located on chr8:85642791-85643987, is a retrocopy of the parental gene REXO1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name REXO1
Full Name RNA exonuclease 1 homolog
Also known as ELOABP1|EloA-BP1|REX1|TCEB3BP1
Coordinate chr19:1815248-1848676
Strand -
Gene summary Predicted to enable exonuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Orangutan Pongo abelii REXO1P1
Crab-eating macaque Macaca fascicularis REXO1P1
Rhesus Macaca mulatta REXO1P1
Baboon Papio anubis REXO1P1
Golden snub-nosed monkey Rhinopithecus roxellana REXO1P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>REXO1L8P
GGGATGGCATGCAAGACCACCGCCACCATCAGCTCTAAGCGAATCGTCCGTCGTCCATCCTTACCGAGTTTGAAGAAACCCATTATCCTCCGAAGCTCTGGGTGCCAAGTCCCCACCGTCCTCCGCCGAGGCTATCTCCAACTGTTCACCGAAGAGTGTCTCAAGTTCTGCGCCTCCAAGCAGGAGGCCGAGGAGAAGGCGCTGAACGAGGAGAAGGTGGCCTACGACTGCAGCCCCAACAAGAACAGGTACCTGAACGTGGTCCTGAACACCCTCAAGAGACTGAAGGGCCTGACCCCCAGCTCCATGCCCGGCCTCAGCAGGGCCGCCCTGTACAGCCGCCTCCAGGAGTTCCTGCTCACCCAGGACCAGCTCAAGGAGAACGGCTACCCCTTCCCGCACCCCGAGCGGCCCGGAGGCGCCGTCCTCTTCACTGGCCAGGGGAAGGGGCCCGGCGACTCCTCCTGCAGGGTCTGCTGCCGTTGTGGCACCGAGTACCTGGTGTCCTCCTCGGGCCGCTGTGTACGCGACCAGTTGTGTTATTATCACTGGGGGCGGGTCCGCTCGAGCCAGGTGGCTGGAGGCCGGGTTAGCCAGTACACCTGCTGTGCAGCTGCTCCTGGCTCTGTGGGCTGCCAGGTGGCAAAGCAGCACGTGCGGGACGGCCGCAAGGAGAGCCTCGATGGCTTCGTGGAGACCTTCAAGAAAGAGTTGTCCAGAGACGCTTATCCAGGAATCTACGCCTTGGACTGTGAGATGTGCTACACCACGCATGGCCTAGAGCTGACCCGCGTCACCGTGGTGGACGCCGACATGCGAGTGGTGTACGACACCTTCGTCAAGCCCGACAACGAGATCGTGGACTACAACACCAGGTTTTCCGGAGTCACCGAGGCCGACGTCGCCAAGACGAGCATCACGTTGCCCCAAGTCCAAGCCATCCTGCTGAGCTTTTTCAGCGCCCAAACCATCCTCATCGGGCACAGCCTGGAGAGCGACCTGCTGGCCCTGAAGCTCATCCACAGCACCGTGGTGGACACGGCCGTGCTCTTCCCGCACTACCTGGGTTTCCCCTACAAGCGCTCCCTCAGGAATCTCGCGGCCGACTACCTGGCACAGATCATCCAGAACAGCCAGGACGGCCACAACTCCAGCGAGGACGCAAACGCCTGCCTGCAGCTGGTGATGTGGAAGGTC
>NM_020695.4
GGGGGCCTCGGAGCAAGATggcggcggcggggtccgtgaggcgcgggcggcggcgaccgcggcgCCAGTGAGGGGGCCCTGGGGCCCGGGCGGCTCCGGGCCGGGGCCCCGCCGCGGGACGGACCATGCTACGCTCCACTGGCTTCTTCCGGGCCATTGACTGCCCCTATTGGTCTGGGGCGCCCGGGGGGCCCTGCCGGCGGCCCTACTGCCACTTCCGGCACCGCGGGGCCCGGGGCTCCGGCGCGCCCGGTGACGGCGGAGAGGCGCCCCCCGCAGCAGGGCTGGGTTACGACCCCTACAACCCTGAGCTGCCCAAGCCCCCCGCGCAGAGGGAGAATGGCACCCTGGGCCTGGGGGAGGAGCCGCGCCCGGATGTGCTGGAGTTGGAGCTGGTCAACCAGGCCATCGAGGCCGTGCGCAGTGAGGTGGAGCTGGAGCAGCGGCGCTACCGGGAGCTGCTGGAGACGACCCGTGAGCACCGCTCCGCCGAGGCCCCCGCCCTGGCGCCCCGCGGCCCCAACGCCAGCCCCACTGTGGGCCCGGACGAGGATGCCTTCCCACTGGCCTTCGACTACAGCCCCGGCAGCCACGGCCTATTAAGCCCTGATGCCGGCTACCAGCCCACCCCACTGGCCGCCCCTGCCGAGCCGGGCAGCAAGTACTCGCTGGCGTCCCTGGACAGGGGTCAGGGCAGAGGTGGAGGGGGTGGCGGTGCCCTGGAATACGTCCCCAAGGCTGTGAGCCAGCCCCGGCGGCACAGCCGCCCCGTTCCCAGTGGCAAGTACGTGGTGGACAACTCCAGGCCACCCACAGACCTGGAGTATGACCCTCTCTCCAACTACTCGGCCCGGCACCTCAGCAGGGCCAGCTCCCGGGATGAGCGGGCCGCCAAGCGGCCCCGGGGCTCCCGCGGCAGTGAGCCCTACACACCTGCTCCCAAGAAGCTCTGTGACCCCTTTGGCAGTTGCGATGCAAGGTTCTCAGACTCAGAAGATGAGGCCGCCACGGTCCCAGGTAACGAGCCCACCACGGCCAGCACCCCCAAAGCCAGGGCCGACCCTGAGATCAAGGCCACCGGGCAGCCACCCTCCAAAGAGGGCCTGGAGGCCGAGGGGGGCGGCCTGCGGGAGACCAAGGAGACGGCCGTGCAGTGCGACGTGGGGGACCTccagccgcccccagccaagcccgcctccccagcccaggtccagtccTCACAGGATGGGGGCTGCCCCAAGGAGGGAAAACCCAAGAAGAAAAAAACCGGGGCCCCACCTGCCCCCAGCTGcaaagacggggcccaggggaaggacaagaccaaggacaagggccgaggGCGGCCTGTGGAGAAGCCCCGTGCGGACAAGAAGGGCCCGCAGGCCAGCAGCCCCCGGCGCAAGGCAGAGCGGCCGGAAGGGACCAAGAAGAAGCCATCTTCGGCCACTCCTGTGGCCACCTCAGGGAAAGGGAGGCCTGACCGGCCAGCGCGGCGGCCGAGCCCCACAAGCGGGGACTCCCGACCGGCGGCCGGCAGAGGCCCACCCCGCCCCCTCCAGCTGCCCGACAGGAAGAGCACCAAGGCCCCGTCGGGGAAGCTAGTGGAGCGGAAAGCCCGCTCACTAGACGAGGGCGCCTCCCAGGACGCCCCCAAGCTGAAGAAGCGGGCCCTGAGCCACGCCGACCTCTTTGGGGACGAGAGTGAGGACGAGGCCGCAGGGCCAGGGGTGCCGAGCGTGTGGCCCTCTGCCCTccccagcctcagctcggactcagactccgactcagactccagcctGGGCTTCCCGGAGGCGCAGGGGCCGCCCAAGCGGCTCAAGGCCTCCCCGCCCCCCTCCCCCGCCCCAtcctcctcctcctcctcctcctcctccacctccAGCGCGGGGGCGGATGTGGACTACTCGGCCCTGGAGAAGGAGGTGGACTTTGACTCCGACCCCATGGAGGAGTGCCTGCGGATCTTCAACGAGTCCACCAGCGTCAAGACGGAGGACAGAGGCCGGCTGGCCCGGCAGCCCCCCAAGGAAGAGAAGAGTGAGGAGAAGGGGCTTTCGGGTCTGACCACTCTGTTCCCCGGGCAGAAGAGGAGGATCTCCCACCTTTCCAAGCAAGGCCAGGAGGTGGAGCCCCCGAGGAGGGGTCCCGCGGTGCCCCCGGCCCGGCCCCCGACGGCGCAGGAGGTGTGCTACCTGCGGGCCCAGCAGGCGCAGAGGGCATCGGCGAGCTTGCTGCAGGCCCCCGCCAGGCTGGCAGAGAAGTCGCCCTCCGTCCACATTTCCGCCCCTGGCGAGAAGAGGAGGATCGCCCACATCCCCAACCCCCGCCTGGCTGCAGCCCCCACAGGTGCCAAGAGGACCCTTGCGGCCAGCGGCAGCCAGTCCTCCAACGGCCCTGAGCCAGGTGGCCAGCAGCTGAAAACACGCACATTGTCGGGGATGGCGTCCAAGACTACCACCACCATCATCCCTAAGCGAATCGCCCACAGTCCATCCTTACAGAGTTTAAAGAAACCCATTATCCCCAAAGAGTTTGGGGGCAAAGTCCCCACCGTCATCCGCCAGCGCTATCTCAACCTGTTCATCGAGGAGTGTCTCAAGTTCTGTACCTCCAACCAGGAGGCCATAGAGAAGGCACTGAACGAGGAGAAGGTGGCCTATGACCGCAGCCCCAGCAAGAACATCTACCTGAATGTGGCCGTGAACACCCTCAAGAAGCTCAGGGGCCTGGCCCCCAGCGCTGTGCCCGGCCTCAGCAAAACCAGTGGCCGCAGGGTTGTGTCCCACGAGGTGGTGTTGGGGGGCAGGTTGGCCGCCAAGACCAGCTTCTCGCTCAGCCGTCCAAGCAGCCCCCGGGTGGAGGACCTGAAAGGGGCTGCCCTGTACAGCCGCCTCAGGGAGTACCTGCTCACCCAGGACCAGCTCAAGGAGAACGGCTACCCCTTCCCGCACCCAGAGCGGCCCGGGGGCGCAATCATCTTCACAGCTGAGGAGAAGAGGCCCAAGGACTCTTCCTGCAGGACCTGCTGCCGCTGTGGCACCGAGTACCTCGTGTCCTCTTCAGGCCGCTGCATCCGGGACGAGGAGTGTTATTACCACTGGGGACGGCTGCGCCGGAACCGGGTGGCCGGAGGCTGGGAGACCCAGTACATGTGCTGCTCGGCTGCCGCCGGCTCTGTCGGCTGCCAAGTCGCAAAGCAACACGTGCAGGATGGCCGGAAGGAGCGCCTTGAGGGCTTCGTGAAGACCTTTGAGAAAGAGCTCTCAGGAGACACCCACCCGGGGATCTACGCCCTGGACTGCGAGATGTCCTACACCACATATGGCCTGGAGCTGACGCGCGTCACGGTGGTCGACACGGACGTGCACGTGGTTTATGACACCTTCGTGAAGCCTGACAACGAGATCGTGGACTACAACACCAGGTTTTCGGGGGTGACGGAGGCTGACCTTGCCGACACAAGTGTCACGCTGCGTGACGTCCAGGCCGTTCTGCTGAGCATGTTCAGCGCTGACACCATCCTCATCGGACACAGCCTGGAGAGCGACCTCCTGGCCCTGAAGGTCATCCACAGCACCGTGGTGGACACGTCTGTGCTCTTCCCCCACCGCCTGGGCCTCCCCTACAAGCGGTCCCTGCGGAACCTCATGGCCGACTACCTCAGACAGATCATCCAGGACAATGTGGATGGGCACAGCTCCAGCGAGGACGCCGGCGCCTGCATGCACCTGGTGATCTGGAAGGTTCGAGAAGACGCCAAGACCAAGCGATGACGCCTGCCCGCCTCCCACCCGCCTCTCCTGCCGTCCCGCTGGTCCTTAGCCCCATGCCTCTTCCAAAACAGTGCAATAAATCTCCGGTAACCCGTCCACCTGGCCGAGGCAGCCCAGAGCAGCGGGATGAGCTGGCGGCCAGAGAACgcccagcccagcccacccccgctcacgtcctgccgcacccctccgccggtccccaccctctgccccccagcccTCTGGCGTCTCTAGAAACTGCTGCTGATGGAGACCAGGACAGAGCCCGCCCCCACCCGGCCCGCAGCCCCTCCTGCCCCTCCTGCCAGGCCCTCCCTCCCGGGTGGTGGCCGGCACCTCTGCTCCTCACGTGGGTCGCGGGGCGGGCTTGTCCCAGGTTTGTTTGAGACAGTCTTtttttattttgtattgttatttttattatttttAATTTAAACCTGATGACTTGCACAGCATCTTTCCCACCGGGAAGAGCGGGCCTGCTGCCTTCCCTCCTGCGGGGTGGGGGTGGGACAGACCCCAGTGGGGGCCAGGGCCACACTCAGCGCAGTGTGGGCTGGACCCGCCTCTGTGCTCCAGGGGCTGGCCGGTCTTCGGGGGCGCCGGCTTCCACCACTCGCCGCCCCACCCCTGCACTCCGTGACCTCTGAGAACCCAGCTGGCCCCTCGTTAGCCCCAGGGTCTGCCGTCTAGAGGGAGCCCACCGGCCTCCGGACACTGTCTTCCCGCTAGAGCCCCGTCCTCCTCTGCGGGGCTCTCCGGACCCCCTTCCCCCTCACCTCCAGGCAGGGACAGAATAAATGTTTGTATGGATTTTA

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