Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CPP
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:91157282-91159966  UCSC
Coordinates (T2T) chr8:92282219-92284903  UCSC
Coordinates (hg19) chr8:92169510-92172194  UCSC
Strand +
Parental Sequence XM_017005735.2
Parental seq. overlap 2404 bp
Parental seq. overlap (%) 51.9%
Genomic Region Intragenic (LRRC69)
Retrocopy Summary CPP, located on chr8:91157282-91159966, is a retrocopy of the parental gene CP. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CP
Full Name ceruloplasmin
Also known as AB073614|CP-2
Coordinate chr3:149162410-149222008
Strand -
Gene summary The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CPP1
Bonobo Pan paniscus CPP1
Gorilla Gorilla gorilla CPP1
Orangutan Pongo abelii CPP1
Gibbon Nomascus leucogenys CPP1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CPP
GGTGTGCCTCCTTCAGCTTCCCATGTGGCACCCACAGAAACATTCACCTATGAATGGACTGTCCCCAAAGAAGTAGGACCCACTAATGCAGATCCTGTATGTCTAGCTAAGATGTATTATTCTGCTGTGGATCCCACTAAAGATATATTCACTGGGCTTATTGGGCCAATGAAAATATGCAAGAAAGGAAGTTTACATGCAAATTGGAGACAGAAAGATGTAGACAAGGAGTTCTATTTGTTTCCTATAGTATTTAATGAGAATGAGGGTTTACTCCTGGAAGATAATATCAGAATGTTTACAACTGCACCTGATCAGGTGGATAAGGCAGATGAAGACTTTCAGGAATCTAATAAAATGCACTGGACTTTTAATGTTGAATGCCTTACAGCTAGCTGATCATTACACAGGCGGCATGAAGCAAAAATATACTGTGAACCAATGCAGGTGGCAGTCTGAGGATTCCACCTTCTACCTGGGAGAGAGGACATACTATATCGCAGCAGTGGAAGTGGAATGGGATTATTCCCCACAAAGGGAGTGGGAAAAGGAGCTGCATCATTTACAAGAGCAGAATGTTTCAAATGCATTTTTAGATAAGGGAGAGTTTTACATAGGCTCAAAGTACAAGAAAGTTGTGTATCGGCAGTATACTGATTGCACGTTCCGTATTCCAGTGGAGAGAAAAGCTGAAGAAGAACATCTGGGAATTCTAGGTCTACAACTTCATGCAGATGTTGGAGACAAAGTCAAAATTATCTTTAAAAACATGACCACAAGGCCCTACTCAATACATGCCCATGGGGTACAAACGGAGAGTTCTACATTTATTCCAGCATTACCAGGTGAAACTCTCACTTACCTATGGAAAATCCCAGAAAGATCTGGAGCTGGAACAGAGGATTCTGCTTGTATTCCATGGGCTTACTATTCAACTGTGGATCAAGTTAAGGATCTCTACAGTGGATTAATTGGCCCCCTGATTGTTTGTCGAAGACATTACTTGAAAGTATTCAATCCCAGAAAGAAACTGGAATTTACCCTTCTGTTTCTAGTTTTTGATGAGAATGAATCTTGGTATTTAGATGACAACATCAAAACAAACTCTGATCACCCCAAGAAAGTAAACAAAGATGATGAGGAATTCATAGAAAGCAATAAAATGCATGCTGTTAATGGAAGAATGTTTGGAAACCCACAAGGCCTCACAATGCACATGGGAGATGAAGCCAATGGGCGATGAAATAGACTTACACACTGTACATTTTCACGGCCATAGCTTCTAATACAAGCACAGGGGTGTTTATAGTTCTGATGTCTTTGACATTTTCCCTGGAACATACCAAACCCTAGAAATGTTTCCAAGAACACCTGGAATTTGGTTACTCCACTGCCATGTGACTGACCACATTCATGCTGGAATGGAAACCACTTACATTGTTCTACAAAATGAAGACACCAAGTCTGGCTGAATGAAATACATTGGTGATAAGTGGAAAAAAGAGAAAAACCAATGATTCATAACAATGTATGTGAAAGTGTAAAATAGAATGTTACTTTGGAATGACTATAAACATTGAAAGAAGACTGGAAACATACAACTTTGTGCATTTGTGGGGGAAAACTATTAATTTTTTGCAAATGGAAACATCAACAGACTATATAATGATACATGACTGACACTTGTACACTAGGTAATAAAATTGATTCCTACAGTCTAATCATATCACCACTATTAGGGTTTTATAAAACTGCATTTAAAAAAAGATCTATGACCAGATATTCTCCTGTGTGCTCCTCAAAGGAACACTATTAAGGTTCATTGAAATGTTTTCAATCATTGCCTTCCCATTGATCCTTCTAACATGCTGTTGACATCACACCTAATATTCAGAGGGAATGGGCAAGGTATGAGGGAAGGTCTGAGTTTTGTGAACCCCTGAAGGGATGGTCTAAAGGACGTTATCTGGAACTGGAGAAAAGCAGAGTTGAGATACAATTCTATAGATTAAATCCTGGTAAGGATAAACATTGCCATTAGAAGAAAAGCTTCAAAATAGACCTGTGGCAGATGTCACATAAGTAGAATTTCTGCCAAGCCTTAACTGCATTCAGAGGATAATATCAATGAACTAAACTTGAACTAAAAATTTTTTAAACAAAAAGTTATAAATGAAGACACATGGTTGTGAATACAATGACATATTTCTTTATTTTCACATACACTCTAGCTGAAAGAGCAAGAGTACACATCAACAAAAAAATGGGAACAAGGCTTTGGCTGAAAAAAACATGCATTTGACAAATCATGTTAATAGCTAGACAAGAAGAAAGTTAGCTTTGTAAACTACTTCATTTGATTCAGAGAAATAGAGCATGAGTTTTCTTAAAGTAAAAAGAAAAGGAACAAAGAAAATGAGGTTTGAAATTTTTTACCATGGCAAAATATTAACATCTTTCTCAAAAACATAGAGAAATCTGGAAAAATCAAGAAGATAAAATTCTGGACCAGTTAGTGACATTCTTTCAAGCATACTTGTAAAATGTTTCCTTAGAGTGTTCTTGGGATGAAAATGATTGTCATGTCTCCAACAACAGTGAACTGATGTTGTTCCTTGGAATAAAAGTCAATCCCCACCTT
>XM_017005735.2
ATTTTCAGTCAGAGAAGCCTGGCAACCAAGAACTGTTTTTTTGGTGGTTTACGAGAACTTAACTGAATTGGAAAATATTTGCTTTAATGAAACAATTTACTCTTGTGCAACACTAAATTGTGTCAATCAAGCAAATAAGGAAGAAAGTCTTATTTATAAAATTGCCTGCTCCTGATTTTACTTCATTTCTTCTCAGGCTCCAAGAAGGGGAAAAAAATGAAGATTTTGATACTTGGTATTTTTCTGTTTTTATGTAGTACCCCAGCCTGGGCGAAAGAAAAGCATTATTACATTGGAATTATTGAAACGACTTGGGATTATGCCTCTGACCATGGGGAAAAGAAACTTATTTCTGTTGACACGGAACATTCCAATATCTATCTTCAAAATGGCCCAGATAGAATTGGGAGACTATATAAGAAGGCCCTTTATCTTCAGTACACAGATGAAACCTTTAGGACAACTATAGAAAAACCGGTCTGGCTTGGGTTTTTAGGCCCTATTATCAAAGCTGAAACTGGAGATAAAGTTTATGTACACTTAAAAAACCTTGCCTCTAGGCCCTACACCTTTCATTCACATGGAATAACTTACTATAAGGAACATGAGGGGGCCATCTACCCTGATAACACCACAGATTTTCAAAGAGCAGATGACAAAGTATATCCAGGAGAGCAGTATACATACATGTTGCTTGCCACTGAAGAACAAAGTCCTGGGGAAGGAGATGGCAATTGTGTGACTAGGATTTACCATTCCCACATTGATGCTCCAAAAGATATTGCCTCAGGACTCATCGGACCTTTAATAATCTGTAAAAAAGATTCTCTAGATAAAGAAAAAGAAAAACATATTGACCGAGAATTTGTGGTGATGTTTTCTGTGGTGGATGAAAATTTCAGCTGGTACCTAGAAGACAACATTAAAACCTACTGCTCAGAACCAGAGAAAGTTGACAAAGACAACGAAGACTTCCAGGAGAGTAACAGAATGTATTCTGTGAATGGATACACTTTTGGAAGTCTCCCAGGACTCTCCATGTGTGCTGAAGACAGAGTAAAATGGTACCTTTTTGGTATGGGTAATGAAGTTGATGTGCACGCAGCTTTCTTTCACGGGCAAGCACTGACTAACAAGAACTACCGTATTGACACAATCAACCTCTTTCCTGCTACCCTGTTTGATGCTTATATGGTGGCCCAGAACCCTGGAGAATGGATGCTCAGCTGTCAGAATCTAAACCATCTGAAAGCCGGTTTGCAAGCCTTTTTCCAGGTCCAGGAGTGTAACAAGTCTTCATCAAAGGATAATATCCGTGGGAAGCATGTTAGACACTACTACATTGCCGCTGAGGAAATCATCTGGAACTATGCTCCCTCTGGTATAGACATCTTCACTAAAGAAAACTTAACAGCACCTGGAAGTGACTCAGCGGTGTTTTTTGAACAAGGTACCACAAGAATTGGAGGCTCTTATAAAAAGCTGGTTTATCGTGAGTACACAGATGCCTCCTTCACAAATCGAAAGGAGAGAGGCCCTGAAGAAGAGCATCTTGGCATCCTGGGTCCTGTCATTTGGGCAGAGGTGGGAGACACCATCAGAGTAACCTTCCATAACAAAGGAGCATATCCCCTCAGTATTGAGCCGATTGGGGTGAGATTCAATAAGAACAACGAGGGCACATACTATTCCCCAAATTACAACCCCCAGAGCAGAAGTGTGCCTCCTTCAGCCTCCCATGTGGCACCCACAGAAACATTCACCTATGAATGGACTGTCCCCAAAGAAGTAGGACCCACTAATGCAGATCCTGTGTGTCTAGCTAAGATGTATTATTCTGCTGTGGAACCCACTAAAGATATATTCACTGGGCTTATTGGGCCAATGAAAATATGCAAGAAAGGAAGTTTACATGCAAATGGGAGACAGAAAGATGTAGACAAGGAATTCTATTTGTTTCCTACAGTATTTGATGAGAATGAGAGTTTACTCCTGGAAGATAATATTAGAATGTTTACAACTGCACCTGATCAGGTGGATAAGGAAGATGAAGACTTTCAGGAATCTAATAAAATGCACTCCATGAATGGATTCATGTATGGGAATCAGCCGGGTCTCACTATGTGCAAAGGAGATTCGGTCGTGTGGTACTTATTCAGCGCCGGAAATGAGGCCGATGTACATGGAATATACTTTTCAGGAAACACATATCTGTGGAGAGGAGAACGGAGAGACACAGCAAACCTCTTCCCTCAAACAAGTCTTACGCTCCACATGTGGCCTGACACAGAGGGGACTTTTAATGTTGAATGCCTTACAACTGATCATTACACAGGCGGCATGAAGCAAAAATATACTGTGAACCAATGCAGGCGGCAGTCTGAGGATTCCACCTTCTACCTGGGAGAGAGGACATACTATATCGCAGCAGTGGAGGTGGAATGGGATTATTCCCCACAAAGGGAGTGGGAAAAGGAGCTGCATCATTTACAAGAGCAGAATGTTTCAAATGCATTTTTAGATAAGGGAGAGTTTTACATAGGCTCAAAGTACAAGAAAGTTGTGTATCGGCAGTATACTGATAGCACATTCCGTGTTCCAGTGGAGAGAAAAGCTGAAGAAGAACATCTGGGAATTCTAGGTCCACAACTTCATGCAGATGTTGGAGACAAAGTCAAAATTATCTTTAAAAACATGGCCACAAGGCCCTACTCAATACATGCCCATGGGGTACAAACAGAGAGTTCTACAGTTACTCCAACATTACCAGGTGAAACTCTCACTTACGTATGGAAAATCCCAGAAAGATCTGGAGCTGGAACAGAGGATTCTGCTTGTATTCCATGGGCTTATTATTCAACTGTGGATCAAGTTAAGGACCTCTACAGTGGATTAATTGGCCCCCTGATTGTTTGTCGAAGACCTTACTTGAAAGTATTCAATCCCAGAAGGAAACTGGAATTTGCCCTTCTGTTTCTAGTTTTTGATGAGAATGAATCTTGGTACTTAGATGACAACATCAAAACATACTCTGATCACCCCGAGAAAGTAAACAAAGATGATGAGGAATTCATAGAAAGCAATAAAATGCATGCTATTAATGGAAGAATGTTTGGAAACCTACAAGGCCTCACAATGCACGTGGGAGATGAAGTCAACTGGTATCTGATGGGAATGGGCAATGAAATAGACTTACACACTGTACATTTTCACGGCCATAGCTTCCAATACAAGACACCAAATCTGGCTGAATGAAATAAATTGGTGATAAGTGGAAAAAAGAGAAAAACCAATGATTCATAACAATGTATGTGAAAGTGTAAAATAGAATGTTACTTTGGAATGACTATAAACATTAAAAGAAGACTGGAAGCATACAACTTTGTACATTTGTGGGGGAAAACTATTAATTTTTTGCAAATGGAAAGATCAACAGACTATATAATGATACATGACTGACACTTGTACACTAGGTAATAAAACTGATTCATACAGTCTAATGATATCACCGCTGTTAGGGTTTTATAAAACTGCATTTAAAAAAAGATCTATGACCAGATATTCTCCTGGGTGCTCCTCAAAGGAACACTATTAAGGTTCATTGAAATGTTTTCAATCATTGCCTTCCCATTGATCCTTCTAACATGCTGTTGACATCACACCTAATATTCAGAGGGAATGGGCAAGGTATGAGGGAAGGAAATAAaaaataaaataaataaaatagaatgacacaaaTTTGAGTTTTGTGAACCCCTGAACAGATGGTCTTAAGGACGTTATCTGGAACTGGAGAAAAGCAGAGTTGAGAGACAATTCTATAGATTAAATCCTGGTAAGGACAAACATTGCCATTAGAAGAAAAGCTTCAAAATAGACCTGTGGCAGATGTCACATGAGTAGAATTTCTGCCCAGCCTTAACTGCATTCAGAGGATAATATCAATGAACTAAACTTGAACTAAAAATTTTTTAAACAAAAAGTTATAAATGAAGACACATGGTTGTGAATACAATGATGTATTTCTTTATTTTCACATACACTCTAGCTAAAAGAGCAAGAGTACACATCAACAAAAATGGAAACAAGGCTTTGGCTGAAAAAAACATGCATTTGACAAATCATGTTAATAGCTAGACAAGAAGAAAGTTAGCTTTGTAAACTTCTACTTCATTTGATTCAGAGAAACAGAGCATGAGTTTTCTTAAAAGTAACAAGAAAAGGAACAAAAAAAATGAGGTTTGAAATCTTTTACCATGGCAAAACATTAACATCTTTCTCAAAAACATAGAGAAATCTGGAAAAATCAAGAAGATAAAATTCTGGACCAGTTAGTGACATTCTTTCAAGCATACTTGTAAAATGTTTCCTTAAAGTGTTCTTGGGATGAAAATGATTGTCATGTCTCCAACAACAGTGAACTGATGTTGTTCCTTGGAATAAAAGTCAATCCCCACCTTAAAAAA

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