Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name IGF2BP2P3
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:99231316-99234459  UCSC
Coordinates (T2T) chr8:100356326-100359469  UCSC
Coordinates (hg19) chr8:100243544-100246687  UCSC
Strand -
Parental Sequence NM_006548.6
Parental seq. overlap 2230 bp
Parental seq. overlap (%) 45.8%
Genomic Region Intragenic (VPS13B)
Retrocopy Summary IGF2BP2P3, located on chr8:99231316-99234459, is a retrocopy of the parental gene IGF2BP2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name IGF2BP2
Full Name insulin like growth factor 2 mRNA binding protein 2
Also known as IMP-2|IMP2|VICKZ2
Coordinate chr3:185643130-185825046
Strand -
Gene summary This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes IGF2BP2P3
Bonobo Pan paniscus IGF2BP2P3
Gorilla Gorilla gorilla IGF2BP2P3
Orangutan Pongo abelii IGF2BP2P3
Gibbon Nomascus leucogenys IGF2BP2P3
Green monkey Chlorocebus sabaeus IGF2BP2P1
Crab-eating macaque Macaca fascicularis IGF2BP2P3
Rhesus Macaca mulatta IGF2BP2P3
Baboon Papio anubis IGF2BP2P2
Golden snub-nosed monkey Rhinopithecus roxellana IGF2BP2P3
Marmoset Callithrix jacchus IGF2BP2P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>IGF2BP2P3
TATTGGAGATGCCGTGAATTTTAATAGGGTATGTGCCATTAGGGCTTCTTGCACTAAAGGATGAACATGTACTGGTTTATGTGAGCAAGCCGTTATACCACCAGACTGCAACACCAGTTTCCTCTACTGCAAACAGTGTTCTGTGACAAAGAAAACACGCAACACCACCCTCGCCCCCGCCCAAGGAAAGCAGTGCTTTGAGTATCCCAACACACAAAAGGAACAAAAGCAAAACACACACGTCAGCCTCAACTTACGCTTGGTTACTCAAAAGAACAAGAGTCAATGGTACTTGTCCTAGCATTTTGGAAGAAGAAAACAGGAACCCACCAAACCAATCAATCAACCAAACAAAGAAAAAATTCCACAATGAAAGAATGTATTTTGTCTTTTTGCATTTTGGTGTATAAGCCATCAATATTCAGCAAAATTATTTCTTTCTTTTTTAAAAAAATGTGAAGGAAAGTAGCAATTTATACAAGGTTGTTGGCCCAGGGCGTTAAATTTACCGATTTTATAAATGAGAAAAACACACAGAAAAAGCTACCTCAGGTGTTTTTTGCCTCAGCACCTTGCTCTTGTGTTTCTCTTAGAGATTTTGTAAAACTGATAGTTGGAGCATTTATTTTCTTAATAAAAATGAGTTGGAAAAAAAATAAGATATCAACAACCAGCCTGGAGAAGGTGAGAGTCCAATTGTGCAACAACTGTTCTGAATTGTCTTCTGCTAGCCAAGAACCTATATGGCCTTCTTTTAGACAAACCTTGAAAACATTTATTAGGTAAAGTGGAATTGCATGGGAAAATCATGGAAGTTGATTACTCGGTCTCTAAAAAGCTAAGGAACAGGAAAATTCAGATTTGAAACATACCTCCTCACCTGCAGTGGGCGATGTTGGATGCACCTTTGGCTCAACACGGGATAGTGGAGAATGTGGAACAAGTCAACACAGACACAGAAACTGCTGTTGTCAATGTCACATATGCAACAAGGGAAGAAGCAAAATAGCCATGGAGGAGCTAAGCGGGCATCAGTTTGAGAACTATTCCTTCAAGATTTCCTACATCCTGGATGAAGAGGTGAGCTCCCCCTTTACCCCCTCAGCGAGCCCAGGGTGGGGACCACTCTTCCGGGAGCAAGGTCACGCCCTGGGGGCTCTTCTCAGGCCGGACAGACTGATTTCCCGCTGCGGATCCAACCCAGTTTGTTGGTGCCATGGTCTGAAAGGAGGGCTTGACCATAGTGAACATCACTGAGCAGACCCAGTCCCGGGTAGACATCCATAGAAAAGAGAACTCTGGAGCTGCAGAGAAGCTTGTCACCATCCATGCCACCCCAGAGGGGACTTCTGAAGCATGCCACACGATTCTTGAAAGCATGCAGAAAGAGGCAGATGAGACCAAACTAGCCGAAGAGATTCCTCTGAAAATCGTGGCCCACAATGGCTTGTTTGGAAGACTGATTGGAAAAGAAGGCAGAAATGTGAAGAAAAATGAACATGAAACAGGGACCAAGATAACAATCTCATCCTTGCAGGATTTGAGCATATGCAACCCGGAAAGAACCATCACTGTGAAGGGCACAGTGGAGGCCTATGCCAGTGCTGAGATGGAGATTATGAAGAAGCTGCGTGAGGCCTTTGAAAATGATATGCTGGCTGTTAATACCCACTCCAGATACTTTCTCCAGCCTGTACCCCCATCACCAGTTTGGCCCGTTCCCGCATCAGCATTCTTATCAAGAGCAGGAGATTGTGAATCTCTTCATCCCAACCCAGGCTGTGGGTACCATCATCGGGAAGAAAGGGGCACACATCAAACAGCTGGCAAGACTCGCCAGAGCCTCCATCAAGGCCCAGGGACGGATCTTCGGGAAACTAAAAGAAGAAAACTTCTTTAACCCCAAAGAAGAAGTGAAGCTGGAAGCCCATATCAGAGTGCTCTCTTCCACAGCTGGCCGGGTGATTGGCAAAGGTGGCAAGACTGTGAATGAACTGCATAACTTAACTAGTGCAGAAATCATTGTGCCTCGTGACCAAACGCCCGATGAAAATGAGGAAGTGATCATCAGAATTATCGGGCACTTCTTTGCTAGCCAGACTGCACAGCGCAGTATCAGGGAAACTGTACAAGAGGTGAAGCAGCAGGAGTAGAAATACCCTCAGGGAGTCGCCTCACAGCGCAGCAAGTGAGGCCTCCCACAGGCATCAGCAAAACAACAGATGAATGGAGCCCTTCCAACACCTGACAAAATGAGACCAAACACAGCCAGCCAGATCGGAAGCAAACCAAAGACCATCTGAGGAATGAGAAGTCTGCGGAGGCGGCCAGGGACTCTGCAGAGGCCCTGAGAATCCCAGGGGCCAAGGAGGCGGGGGAAGGTCAGCCAGGTTTGCCAGAACCTCCGGGCCCTGCCTCCTACCTCCCAGGACTTCTGCAGCTTCAGCAATCCACTTCACCATCCACTCAGATCTCTCCTTAACTCCCACAATGCTGTACCTTTTGGTTGAAGTAACATAGGTGAACGTGTTCAAAGCCATGCAAAATGCACACCCTTTTTTGTGGCAAATCTCTGTACATGTGTGCACATATTAGAAGGGGACGATGGTAAGATACGTGGCCTGCGGGTTACGCAGGGTGCCTGCAGCGGTAATATGTTTTAGAAATAACATATCAAATAACTCAACTAATTCCAATTTTTAATCAACTATTAATTTTTTTTTCTTTTTAAAGAGAAAGCAGGCTTTTCTAGACTTTAAAGTCTTTCTTTGGGAGGTTCACGGTGTAGAGAGGAGCTTCGAGGTGACCTACACAAAATTCACCCAGAGGGAAATCTTGTCGGAAGGACACTCACAGCAATTATGGATCATCTGTGTATATCAACAGGAGGGATACCATCTCCTTGAAAAGGAAACTCTGTCACTCCTCATGCCTGTCTAGCTTATACATCCATTTCTCTTTGCTTCATGGGTTTTAAACTGGTTTTTCGCATACTGCTATATAATt
>NM_006548.6
gaggagagacgagggcagcggaggaggcgaggagCGCCGGGTACCGGGCCGGGGGAGCCGCGGGCTCTCGGGGAAGAGACGGATGATGAACAAGCTTTACATCGGGAACCTGAGCCCCGCCGTCACCGCCGACGACCTCCGGCAGCTCTTTGGGGACAGGAAGCTGCCCCTGGCGGGACAGGTCCTGCTGAAGTCCGGCTACGCCTTCGTGGACTACCCCGACCAGAACTGGGCCATCCGCGCCATCGAGACCCTCTCGGGTAAAGTGGAATTGCATGGGAAAATCATGGAAGTTGATTACTCAGTCTCTAAAAAGCTAAGGAGCAGGAAAATTCAGATTCGAAACATCCCTCCTCACCTGCAGTGGGAGGTGTTGGATGGACTTTTGGCTCAATATGGGACAGTGGAGAATGTGGAACAAGTCAACACAGACACAGAAACCGCCGTTGTCAACGTCACATATGCAACAAGAGAAGAAGCAAAAATAGCCATGGAGAAGCTAAGCGGGCATCAGTTTGAGAACTACTCCTTCAAGATTTCCTACATCCCGGATGAAGAGGTGAGCTCCCCTTCGCCCCCTCAGCGAGCCCAGCGTGGGGACCACTCTTCCCGGGAGCAAGGCCACGCCCCTGGGGGCACTTCTCAGGCCAGACAGATTGATTTCCCGCTGCGGATCCTGGTCCCCACCCAGTTTGTTGGTGCCATCATCGGAAAGGAGGGCTTGACCATAAAGAACATCACTAAGCAGACCCAGTCCCGGGTAGATATCCATAGAAAAGAGAACTCTGGAGCTGCAGAGAAGCCTGTCACCATCCATGCCACCCCAGAGGGGACTTCTGAAGCATGCCGCATGATTCTTGAAATCATGCAGAAAGAGGCAGATGAGACCAAACTAGCCGAAGAGATTCCTCTGAAAATCTTGGCACACAATGGCTTGGTTGGAAGACTGATTGGAAAAGAAGGCAGAAATTTGAAGAAAATTGAACATGAAACAGGGACCAAGATAACAATCTCATCTTTGCAGGATTTGAGCATATACAACCCGGAAAGAACCATCACTGTGAAGGGCACAGTTGAGGCCTGTGCCAGTGCTGAGATAGAGATTATGAAGAAGCTGCGTGAGGCCTTTGAAAATGATATGCTGGCTGTTAACCAACAAGCCAATCTGATCCCAGGGTTGAACCTCAGCGCACTTGGCATCTTTTCAACAGGACTGTCCGTGCTATCTCCACCAGCAGGGCCCCGCGGAGCTCCCCCCGCTGCCCCCTACCACCCCTTCACTACCCACTCCGGATACTTCTCCAGCCTGTACCCCCATCACCAGTTTGGCCCGTTCCCGCATCATCACTCTTATCCAGAGCAGGAGATTGTGAATCTCTTCATCCCAACCCAGGCTGTGGGCGCCATCATCGGGAAGAAGGGGGCACACATCAAACAGCTGGCGAGATTCGCCGGAGCCTCTATCAAGATTGCCCCTGCGGAAGGCCCAGACGTCAGCGAAAGGATGGTCATCATCACCGGGCCACCGGAAGCCCAGTTCAAGGCCCAGGGACGGATCTTTGGGAAACTGAAAGAGGAAAACTTCTTTAACCCCAAAGAAGAAGTGAAGCTGGAAGCGCATATCAGAGTGCCCTCTTCCACAGCTGGCCGGGTGATTGGCAAAGGTGGCAAGACCGTGAACGAACTGCAGAACTTAACCAGTGCAGAAGTCATCGTGCCTCGTGACCAAACGCCAGATGAAAATGAGGAAGTGATCGTCAGAATTATCGGGCACTTCTTTGCTAGCCAGACTGCACAGCGCAAGATCAGGGAAATTGTACAACAGGTGAAGCAGCAGGAGCAGAAATACCCTCAGGGAGTCGCCTCACAGCGCAGCAAGTGAGGCTCCCACAGGCACCAGCAAAACAACGGATGAATGTAGCCCTTCCAACACCTGACAGAATGAGACCAAACGCAGCCAGCCAGATCGGGAGCAAACCAAAGACCATCTGAGGAATGAGAAGTCTGCGGAGGCGGCCAGGGACTCTGCCGAGGCCCTGAGAACCCCAGGGGCCGAGGAGGGGCGGGGAAGGTCAGCCAGGTTTGCCAGAACCACCGAGCCCCGCCTCCCGCCCCCCAGGGCTTCTGCAGGCTTCAGCCATCCACTTCACCATCCACTCGGATCTCTCCTGAACTCCCACGACGCTATCCCTTTTAGTTGAACTAACATAGGTGAACGTGTTCAAAGCCAAGCAAAATGCACACCCTTTTTCTGTGGCAAATCGTCTCTGTACATGTGTGTACATATTAGAAAGGGAAGATGTTAAGATATGTGGCCTGTGGGTTACACAGGGTGCCTGCAGCGGTAATATATTTTAGAAATAATATATCAAATAACTCAACTAACTCCAATTTTTAATCAATTATTAATTTTTTTTTCTTTTTAAAGAGAAAGCAGGCTTTTCTAGACTTTAAAGAATAAAGTCTTTGGGAGGTCTCACGGTGTAGAGAGGAGCTTTGAGGCCACCCGCACAAAATTCACCCAGAGGGAAATCTCGTCGGAAGGACACTCACGGCAGTTCTGGATCACCTGTGTATGTCAACAGAAGGGATACCGTCTCCTTGAAGAGGAAACTCTGTCACTCCTCATGCCTGTCTAGCTCATACACCCATTTCTCTTTGCTTCACAGGTTTTAAACTGGTTTTTTGCATACTGCTATATAATtctctgtctctctctgtttatctctcccctccctcccctccccttcttctccatctcCATTCTTTTGAATTTCCTCATCCCTCCATCTCAATCCCGTATCTACGCACCCCCCCCCCCCCAGGCAAAGCAGTGCTCTGAGTATCACATCACACAAAAGGAACAAAAGCGAAACACACAAACCAGCCTCAACTTACACTTGGTTACTCAAAAGAACAAGAGTCAATGGTACTTGTCCTAGCGTTTTGGAAGAGGAAAACAGGaacccaccaaaccaaccaatcaaccaaacaaAGAAAAAATTCCACAATGAAAGAATGTATTTTGTCTTTTTGCATTTTGGTGTATAAGCCATCAATATTCAGCAAAATGATTCCTTTCTTTAAAAAAAAAAAATGTGGAGGAAAGTAGAAATTTACCAAGGTTGTTGGCCCAGGGCGTTAAATTCACAGATTTTTTTAACGAGAAAAACACACAGAAGAAGCTACCTCAGGTGTTTTTACCTCAGCACCTTGCTCTTGTGTTTCCCTTAGAGATTTTGTAAAGCTGATAGTTGGAGCATTTTTTTATTTTTTTAATAAAAATGAGTTGGAAAAAAAATAAGATATCAACTGCCAGCCTGGAGAAGGTGACAGTCCAAGTGTGCAACAGCTGTTCTGAATTGTCTTCCGCTAGCCAAGAACCTATATGGCCTTCTTTTGGACAAACCTTGAAAATGTTTATTTAAAAAAAAAAAAGATGACAAAGAAAAACAGAGAGAGAGAATATTGGAGATGTCCTGAATTTTAATAGGGTACGCGCCATTAGGGCTTTTTGCGCTAAAGGATGAACATGTACTGGTTTATGTGGACAAGCCATTATACCACCAGACTGCAATGCCAGTTTCCTCTACTGCAAACAGTGTTCTGTGACaaaaaaaaaaaaaaaaaaaagaaaaaaaaagaaaaaacagaaaTATATCCAGCTAACAAGATCCTGGTGTCTTGGTGTTTTATTTTACTAGGCATTGCCTCATCCCAGGTGTCAGCTGAGTCCTAGCTCTGAGGGACCTGGGCAGACAGGCGGTAGGTGTGACCTGGATCCACACAGCTACTCTGAGAAAGCTGGTTTTGCCCAGGAAAGTCTTTGGGAGAAGCTAAACTAGATcggtggtcaaagtgtagtccccagaccagcagcatcagctatcatctgggaacttgttagaaatgtagattcttggggtccaccttgaatcagaaatcctgggggtgaggcccagcaaccttttcagcaaggcctctgggtgattgctgtgcgcactgaagtttccgaaccTCGGAGCTAGAGGGATGGATCGACTGCATGTCAAGCTAGAGAAGACCAGTCTATCCTTAAGGAACTGCAAGCCTGGCCAGGCAAAGCTGCTTTTTAAGTGGAGGAAAGGGGGAGGATAATATGCCCGGCAGTTCCGGGAAGAGGCACTTCACGCCTCCACGGGAAGCTCACTAGTAAGTGcaggcatacctcaggaacgtcgcaggttcagttccagaccaccacagtaaagcgaactttgcaataaaatgagtcatacacgttt

Publications

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