Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SERF2P6
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:114491511-114492013  UCSC
Coordinates (T2T) chr9:126683904-126684406  UCSC
Coordinates (hg19) chr9:117253791-117254293  UCSC
Strand +
Parental Sequence NM_001018108.4
Parental seq. overlap 454 bp
Parental seq. overlap (%) 17.8%
Genomic Region Intragenic (WHRN)
Retrocopy Summary SERF2P6, located on chr9:114491511-114492013, is a retrocopy of the parental gene SERF2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SERF2
Full Name small EDRK-rich factor 2
Also known as 4F5REL|FAM2C|H4F5REL|HsT17089
Coordinate chr15:43777086-43796089
Strand +
Gene summary Involved in protein destabilization. Predicted to be located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SERF2P6
Bonobo Pan paniscus SERF2P6
Gorilla Gorilla gorilla SERF2P6
Orangutan Pongo abelii SERF2P6
Gibbon Nomascus leucogenys SERF2P3
Green monkey Chlorocebus sabaeus SERF2P2
Crab-eating macaque Macaca fascicularis SERF2P6
Rhesus Macaca mulatta SERF2P6
Baboon Papio anubis SERF2P6
Golden snub-nosed monkey Rhinopithecus roxellana SERF2P9
Marmoset Callithrix jacchus SERF2P2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SERF2P6
GGACAGAATGAGGGGATGCAACGGAGGCAGGTCGGAGCCGCTGCCATCACCATGACCTGTGGTAACCAGCAAGAGCTCCCCACCAGAAGAGTATGAAAAAGCAGAGCGCGCCTCGGTTAAGGGAAAGCACCAAGATGACAGGCTTTTTGCCGCCACCCGCAAGCAGAGGGACTTGGAGATCATGCAGCAGAAGGAGAAAAAGGCAAACGAGAAGCAGCAGGAACCCAAGTAGCTTTGTGCTTCGTGTCCAACCCTCCCGCCCTTTGCCTGAGTGCCTGGAGCCAGTCCCACCATGCCCACGTCTCCTCCTGCAGGGCCCACAAGTCCCAGCCCTGATGGCTTCCCTTTGCCCTGAGTCTGCAGCGGGTCCCTTTTGTGCTTCCTTCCCCCATCAGGTGGCCTCTCTCCTCCTGGGTCACTCCCGGGGTGACAAGGTTACCCCTTCCCAGTGTTTTTTATTCCTGTGGCGCTCACCCCAAAGTATTAAAAGTAGCTTTGTAATT
>NM_001018108.4
AACGTCCGACAGAACGAGGGGACGTAACGGAGGCAGGTTGGAGCCGCTGCCGTCGCCATGACCCGCGGTAACCAGCGTGAGCTCGCCCGCCAGAAGAATATGAAAAAGCAGAGCGACTCGGTTAAGGGAAAGCGCCGAGATGACGGGCTTTCTGCTGCCGCCCGCAAGCAGAGGGACTCGGAGATCATGCAGCAGAAGCAGAAAAAGGCAAACGAGAAGAAGGAGGAACCCAAGTAGCTTTGTGGCTTCGTGTCCAACCCTCTTGCCCTTCGCCTGTGTGCCTGGAGCCAGTCCCACCACGCTCGCGTTTCCTCCTGTAGTGCTCACAGGTCCCAGCACCGATGGCATTCCCTTTGCCCTGAGTCTGCAGCGGGTCCCTTTTGTGCTTCCTTCCCCTCAGGTAGCCTCTCTCCCCCTGGGCCACTCCCGGGGGTGAGGGGGTTACCCCTTCCCAGTGTTTTTTATTCCTGTGGGGCTCACCCCAAAGTATTAAAAGTAGCTTTGTAATTCCTTGAGCGCCTGGTTTGACTGGGGACTTGGGGGGATGGGGTTGGAAGAATGACTGCCCTTTCCCACCAAAAAAGGGAGAACTCTTTAGATTCAGATTGTGGGTATGTAGACTTAATAAGTGAAACATCACAGAAGAAGCCTTTATTATACAATGACAACCAAACAAGTACTCCGGATATGCAGTAGAGGAATCCTCTAAGAACCATAGAGACTTCTTTTCTGTGATTTTTGTTCCCCACCCTTGAACACCATCTCTAGGATGGAGTTGGCCTAAGAGTGAATGCTGCAAGATCTGTGTTTATGCCTCTTTTCCTCATTCTTCCTCAGTTTGTTCGTCTGCTTGAAAGTTGGCCAAAAAATCCTGCTGCTCACCGACTTCCCGTGGTCAGCTGCTGTCAAGCGTTCACTTTCTCTTCTGTCATTCCTCATGGAATGAGGGTGGTTTTGTCTTCCCGCTTCCCTTGACCTCAAAATCAGGATTAAAACCTGGGGTAGCCTCTGTGCTCCTTTCTTCTATGCCCTGGTTTGTTCTGTGGTTCTGGGCTTCTTATATCCGTGTGCCCAGGGCTGAACTCCTTATTTTCCTTTCTCCAAGGGCAGAGCCGAGTCTTCAGTCCCTGTTGGTCTTTCCCCACCCCCACTTCCAGCCCAAGAGCCAGGAAAGGGCTGGTGCCACACTGTCTGCTGGGATCAGCGGTGGTTCTTTGAGCTGCTGATTTGGGTGTTAGGCTCTTGAGCTGGGATGCAGATGTAACAGTAGCTCCAGTGAGTCAGACACTCTGCCCAGCACATTAGACTGTGTTTGACCACTTCTTCCAGTTCATAGTATTGACTTCAGCCCAAACGGAGATAACTCCCTGTGTGTCCTTGAGGTATTGAGCTGGGCTGGACAGCTCCCCTTGAGCCAACTCTAGGAGTACAATGTCAGGGGAACCCCAGTTTGTGAAAAGGACTTAGACTGGAGGATATTTGTTATCTGGGGATATGATGCGGTGGCGGCGGCGCCTCAAGATAAGGGGCTGGGGTTTCTGGGTGGGGGGCCAACAGAGTGGTGCCAGTAACAGCCCCAGATAGAGGAGTACGCAGGCCCAGCATGAGGCAACCTTGACCCAGAAGGTGGCCCAGCTACCCTTGATGAAGGTCTTTTCCAGTTCTGCTCCCTCATAGCTGTGTAACCAAAGGCTCTGGTTAGAGAATATGAAGGGCCTTAGCTTTTAGACCTGTTCTACCTCCTCACCAAATATAATGGCAGACCCATGTGTGTCTGGAATGGCCTTGAATTGCTCTTTCCTTAAAATAGCTAGCTCTTCAGGAGAGTATCTAAGGCCCACTCCATCTTACCTGAACCAGTTGGTAAGGGTAACCATGACATAGAGTGAGGCAAGGAAGAAGACGAAGTGGAAGGCAGAATAGTTGTAGGAAAGATGCTGGACTTGGACTGGAGGAGCTGGAGGGGTTTCTTGGTCAGCTGGCCTCGCAGCCCCACCCCTTTGCCCTGGAGAGAGGAAATGGCTGCTGGGAGCAGAGCTGCTGAAACACCTCTTCCCCTCTCCCCCAACTACCTTTGTTAAGGCTCTTGAGGGTTCTTATGGCACTCCACAGAGATCTACCACTTCTTATGGTTCCTCACTTGGCACTCACCTTTGTCTGCCTCCACTGTTTCAGGGCAGCAGAAACACAGTGAGGGCTTCTGCAAAACAGAACGCAGGTTTTGGAATGGTCTTAAAAGATGTGAGGGTGTTAATCTAGGAAACTTCCCCCGTGAAAAGATtggtctagtattaaaaagtggaggcacacctgggttcaaattctagctccagcatataagtggctgtgcagactttggtaagatgtttaatcttttgtgcctcgatttctccatttgtaaaatggagcaaatacctacctcacagggttgttgtgagggttaaattaaatgagattatgtaaaagtatctagcacagttgcctagcacattgtgggtactcaataaaaggtaacAGCAGCTATAATCTGAGCATTCTGGGTA

Publications

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