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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name AHCYP2
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Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:120720599-120722120  UCSC
Coordinates (T2T) chr9:132916755-132918274  UCSC
Coordinates (hg19) chr9:123482877-123484398  UCSC
Strand +
Parental Sequence NM_000687.4
Parental seq. overlap 1340 bp
Parental seq. overlap (%) 62.1%
Genomic Region Intergenic
Retrocopy Summary AHCYP2, located on chr9:120720599-120722120, is a retrocopy of the parental gene AHCY. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AHCY
Full Name adenosylhomocysteinase
Also known as SAHH|adoHcyase
Coordinate chr20:34235012-34311976
Strand -
Gene summary S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes AHCYP4
Bonobo Pan paniscus AHCYP5
Gorilla Gorilla gorilla AHCYP5
Orangutan Pongo abelii AHCYP5
Gibbon Nomascus leucogenys AHCYP3
Green monkey Chlorocebus sabaeus AHCYP5
Crab-eating macaque Macaca fascicularis AHCYP9
Rhesus Macaca mulatta AHCYP8
Baboon Papio anubis AHCYP6
Golden snub-nosed monkey Rhinopithecus roxellana AHCYP9
Marmoset Callithrix jacchus AHCYP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Related Sequence

>AHCYP2
ACTGCCCACCCAGTGCCTGTCCCCAGACTATGGCCCAGCCCCCTTTGCCCTTGTCCATCAAAGGTGCCGCCAGCATGTCTGACAAACTGCCCTACAAAGTTGCTGACATCGGCCTGGCCACCTGGGGACACAAGGCCCTAGACATTGTGGAGAATGGATGCCGGGTTTGATGGGCATGCAGGAGCTTTACTCGGCCTCCAGGCCACTGAAGGGTGCCTGCATTGCTGACTGCCTGCAAATAACTGTGGAGACGGCCATCCTCATTGAGACCCTTTTCTCCCTGGGTGTTCAGGAGCAGTGGTCTAGCTGCAGCATCTTCTCCACCCAGGAACATGCAGTGGCTGTCTTTGCCGAGGCTGGCATGCCAGTGTTCACCTGGAAGGGCAAAATGAAAGAGGGGTACCCGTGGTGCATTGAACAGACACTGTACTTCAAGGACGGGCCCCTCAACATGATTCTGGATGATGGGGGTGACCTTACCAACCTCATCCACACCAAGTACGTACCCACAGCTCATGTCGGGCATCTGAGGCATCTCTGAGGAGACCAAAACCGGGGTCCACAACCTACACAAGATGATGGCCAGTGCAATCCTGAAGGTGCCTACCATCAACGTCAATGACTCCGTCACCAAGAGCAAAATTTGACAACCTCTATGGCTGCCAGGAGTCCCTTATAGATGGCACCAAGTGGACCAAGACGTGATGATTGCCAGCAAGGTAGCAGTGGTAGCAGGCTATGGTGGTGTGGGCAAGGGCTGTGCCCAGGCCTTGCAGGGTTTTGGGGCCTGCATAATCATCACCGAGACTGACCCCATCAGTGCACTGCAGGCTGCCATGGAAGGCTATGAGGTGACCACCATGGACGAGGCCTGTCAGGAGGGCAACATCTTTGTCACCACCACAACCTGTGTCAATATCATCCTTGGCCGGCACTTTGAGCAGATGAAGGATGATGCCATCTTATGTAATACTGAACAATTTGACGTGGAGATCGATGTCAGGTGCCTCAACAACAATGCTGTGGAGAAGGCAAACATCAAGCCCAGGCGGACTGGTACTGGCTGAAGAATGGGTGCCACATCATCGTGCTGGCTGAGGGTTGGCTGGTCAACCTGGGCTGTGCTATGGGCCGCCCCAGCTTTGTGGGGAGTAACTCCTTCAACCAGGTGATGGTGCAGATTGCGCTGTGGACCCACCCAGACAAGTACCCCATTGGGGTTCACTTCCTGCCCAAGAAGCTGGATGAGGCAGTGGCTGAGGCGCCCCCCTGGGCAAGATGAACGTGAAATTGACCAAGCTAACTGAGAAGCAAGCCCAGTAGCTGAGCACGTCCCGTGATGGCCCCTTCAAGCCGGATCACTACTGCTGCTGAGAGTCAGGCCTGCCCTTCACTTTCCAGCTGCTGTCCTTGCTCAGGCCCCGCCTCTTCTCCCTAAGAGCAAATGGCACCAACTTTGTGATTGGTTGGTTAGTGTCCCCCATCGATGGGGCTGGTCACTCAGTTTTTGGCCTCTGCTGCA
>NM_000687.4
CCCTGCTCGGCGCTGCCCGCCCAGTTCCTGTTCCCAGACTGAGGCCCAGCCCCCTTCGCCCGTTTCCATCACGAGTGCCGCCAGCATGTCTGACAAACTGCCCTACAAAGTCGCCGACATCGGCCTGGCTGCCTGGGGACGCAAGGCCCTGGACATTGCTGAGAACGAGATGCCGGGCCTGATGCGTATGCGGGAGCGGTACTCGGCCTCCAAGCCACTGAAGGGCGCCCGCATCGCTGGCTGCCTGCACATGACCGTGGAGACGGCCGTCCTCATTGAGACCCTCGTCACCCTGGGTGCTGAGGTGCAGTGGTCCAGCTGCAACATCTTCTCCACCCAGGACCATGCGGCGGCTGCCATTGCCAAGGCTGGCATTCCGGTGTATGCCTGGAAGGGCGAAACGGACGAGGAGTACCTGTGGTGCATTGAGCAGACCCTGTACTTCAAGGACGGGCCCCTCAACATGATTCTGGACGACGGGGGCGACCTCACCAACCTCATCCACACCAAGTACCCGCAGCTTCTGCCAGGCATCCGAGGCATCTCTGAGGAGACCACGACTGGGGTCCACAACCTCTACAAGATGATGGCCAATGGGATCCTCAAGGTGCCTGCCATCAATGTCAATGACTCCGTCACCAAGAGCAAGTTTGACAACCTCTATGGCTGCCGGGAGTCCCTCATAGATGGCATCAAGCGGGCCACAGATGTGATGATTGCCGGCAAGGTAGCGGTGGTAGCAGGCTATGGTGATGTGGGCAAGGGCTGTGCCCAGGCCCTGCGGGGTTTCGGAGCCCGCGTCATCATCACCGAGATTGACCCCATCAACGCACTGCAGGCTGCCATGGAGGGCTATGAGGTGACCACCATGGATGAGGCCTGTCAGGAGGGCAACATCTTTGTCACCACCACAGGCTGTATTGACATCATCCTTGGCCGGCACTTTGAGCAGATGAAGGATGATGCCATTGTGTGTAACATTGGACACTTTGACGTGGAGATCGATGTCAAGTGGCTCAACGAGAACGCCGTGGAGAAGGTGAACATCAAGCCGCAGGTGGACCGGTATCGGTTGAAGAATGGGCGCCGCATCATCCTGCTGGCCGAGGGTCGGCTGGTCAACCTGGGTTGTGCCATGGGCCACCCCAGCTTCGTGATGAGTAACTCCTTCACCAACCAGGTGATGGCGCAGATCGAGCTGTGGACCCATCCAGACAAGTACCCCGTTGGGGTTCATTTCCTGCCCAAGAAGCTGGATGAGGCAGTGGCTGAAGCCCACCTGGGCAAGCTGAATGTGAAGTTGACCAAGCTAACTGAGAAGCAAGCCCAGTACCTGGGCATGTCCTGTGATGGCCCCTTCAAGCCGGATCACTACCGCTACTGAGAGCCAGGTCTGCGTTTCACCCTCCAGCTGCTGTCCTTGCCCAGGCCCCACCTCTCCTCCCTAAGAGCTAATGGCACCAACTTTGTGATTGGTTTGTCAGTGTCCCCCATCGACTCTCTGGGGCTGATCACTTAGTTTTTGGCCTCTGCTGCAGCCGTCATACTGTTCCAAATGTGGCAGCGGGAACAGAGTACCCTCTTCAAGCCCCGGTCATGATGGAGGTCCCAGCCACAGGGAACCATGAGCTCAGTGGTCTTGGAACAGCTCACTAAGTCAGTCCTTCCTTAGCCTGGAAGTCAGTAGTGGAGTCACAAAGCCCATGTGTTTTGCCATCTAGGCCTTCACCTGGTCTGTGGACTTATACCTGTGTGCTTGGTTTACAGGTCCAGTGGTTCTTCAGCCCATGACAGATGAGAAGGGGCTATATTGAAGGGCAAAGAGGAACTGTTGTTTGAATTTTCCTGAGAGCCTGGCTTAGTGCTGGGCCTTCTCTTAAACCTCATTACAATGAGGTTAGTACTTTTAGTCCCTGTTTTACAGGGGTTAGAATAGACTGTTAAGGGGCAACTGAGAAAGAACAGAGAAGTGACAGCTAGGGGTTGAGAGGGGCCAGAAAAACATGAATGCAGGCAGATTTCGTGAAATCTGCCACCACTTTATAACCAGATGGTTCCTTTCACAACCCTGGGTCAAAAAGAGAATAATTTGGCCTATAATGTTAAAAGAAAGCAGGAAGGTGGGTAAATAAAAATCTTGGTGCCTGGAA

Publications

PMID - Link Title
No publications available for this retrocopy